Indole-3-Butyric Acid

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  • Identifiers

    CAS number
    133-32-4

    Molecular formula
    C12H13NO2

    SMILES
    C1=CC=C2C(=C1)C(=CN2)CCCC(=O)O

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 36.0%
    Animal 35.73%
    Floral 31.5%
    Honey 31.42%
    Grape 29.88%
    Fatty 27.9%
    Cooked 24.88%
    Savory 22.89%
    Meaty 22.87%
    Sweet 22.82%

     

    Flavor
    Odorless 54.75%
    Mild 47.35%
    Sour 34.92%
    Faint 27.64%
    Fruity 26.96%
    Bitter 26.18%
    Sweet 25.4%
    Honey 24.25%
    Waxy 22.96%
    Honeysuckle 22.28%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    6.79 (neutral)

    Molecular weight
    203.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    403°C

    Melting point expt.

    • 124.5 °C

    Flash point

    • 223.61 ˚C est.

    Solubility expt.

    • 250 mg/L (at 20 °C)
    • In benzene: >1000 g/L; in acetone, ethanol, diethyl ether: 30-100 g/L; in chloroform: 0.01-1 g/L
    • In water, 250 mg/L @ 20 °C
    • 0.25 mg/mL at 20 °C

  • Synonyms

    • Indole-3-butyric acid
    • 133-32-4
    • 3-Indolebutyric acid
    • 4-(1H-Indol-3-yl)butanoic acid
    • Indolebutyric acid
    • Hormodin
    • Seradix
    • 1H-INDOLE-3-BUTANOIC ACID
    • Jiffy grow
    • 4-indol-3-ylbutyric acid
    • Indole-3-butanoic acid
    • 4-(3-Indolyl)butyric acid
    • Indolbutyric acid
    • Seradix 2
    • Seradix 3
    • 4-(Indol-3-yl)butyric acid
    • 1H-Indole-3-butyric acid
    • IBA
    • Seradix B 2
    • Seradix B 3
    • Rhizopon AA
    • beta-Indolebutyric acid
    • Butyric acid, 4-(indolyl)-
    • Indol-3,4'-yl butyric acid
    • Caswell No. 499
    • 3-Indolylbutyric acid
    • 3-Indolebutyric acid (IBA)
    • 3-Indolyl-gamma-butyric acid
    • CCRIS 1020
    • 3-Indolebutyricacid
    • HSDB 7214
    • NSC 3130
    • 933-32-4
    • 4-(3-Indolyl)butanoic acid
    • Indole 3-butyric acid
    • Indolyl-3-butyric acid
    • EPA Pesticide Chemical Code 046701
    • CHEBI:33070
    • 3-Indolebutyrate
    • AI3-17434
    • EINECS 205-101-5
    • 4-Indol-3-ylbutyric acid [BSI:ISO]
    • BRN 0171120
    • Kyselina 4-indol-3-ylmaselina
    • Kyselina 4-indol-3-ylmaselina [Czech]
    • 061SKE27JP
    • .beta.-IBA
    • DTXSID8032623
    • 3-Indole butyric acid
    • 4-(1H-Indol-3-yl)butyric acid
    • 4-(1H-Indol-3-yl)-butyric acid
    • NSC-3130
    • 1H-Indole-3-butanoic acid (9CI)
    • MFCD00005664
    • .beta.-Indolebutyric acid
    • INDOLEBUTYRIC ACID [MI]
    • 3-Indolyl-.gamma.-butyric acid
    • DTXCID6012623
    • .gamma.-(3-Indolyl)butyric acid
    • .gamma.-(Indole-3)-butyric acid
    • .gamma.-(Indol-3-yl)butyric acid
    • 5-22-03-00140 (Beilstein Handbook Reference)
    • 4-INDOL-3-YLBUTYRIC ACID [ISO]
    • 4-INDOL-3-YLBUTYRIC ACID [HSDB]
    • 1H-Indole-3-butyrate
    • beta-Indolylbutyric acid
    • 1H-Indole-3-butanoate
    • 4-(3-Indolyl)butyric acid 100 microg/mL in Acetonitrile
    • gamma-(Indol-3-Yl)butyric acid
    • 3IB
    • SR-01000477768
    • 4-indol-3-ylbutanoic acid
    • UNII-061SKE27JP
    • Indolebutyrate
    • Chryzopon
    • Chryzosan
    • Chryzotek
    • Oxyberon
    • Hormex
    • b-Indolebutyrate
    • 3-Iodolebutyrate
    • 3-Indole butyrate
    • beta-Indolebutyrate
    • Indole 3-butyrate
    • Indole-3 Butyrate
    • 3Indolebutyric acid
    • Indolyl-3-butyrate
    • Indole-3-Butrylate
    • b-Indolebutyric acid
    • Indole3butanoic acid
    • 3-indolebutyric-acid
    • 3-Indolybutyric acid
    • betaIndolebutyric acid
    • 1HIndole3butyric acid
    • 4-indol-3-ylbutyrate
    • 1HIndole3butanoic acid
    • Indole-3 Butyric acid
    • Indole-3-Butrylic acid
    • 4-(indolyl)- butyrate
    • Enamine_005659
    • 3Indolylgammabutyric acid
    • 4-(3-Indolyl)butyrate
    • 4(Indol3yl)butyric acid
    • 4-(3-Indole)-butyrate
    • 4-(Indol-3-yl)butyrate
    • Kyselina 4indol3ylmaselina
    • .gamma.-Indolebutyric acid
    • 4-Indol-3-ylbutyric-acid
    • Butyric acid, 4(indolyl)
    • CBKinase1_000084
    • CBKinase1_012484
    • Indol3,4'yl butyric acid
    • 4-(3-Indole)butyric acid
    • 4-(indolyl)- butyric acid
    • 4-(Indol-3)-butyric acid
    • 4-(3-1H-Indolyl)butyrate
    • Oprea1_093618
    • Oprea1_136608
    • SCHEMBL35884
    • 3-Indolebutyric acid, 98%
    • 4-(3-Indole)-butyric acid
    • CBDivE_001082
    • MLS006011821
    • 4-(3-Indolyl)-butyric acid
    • WLN: T56 BMJ D3VQ
    • .gamma.-Indole-3-butyric acid
    • CHEMBL582878
    • gamma-(Indole-3)-butyric acid

  • Applications

    Indole-3-Butyric Acid (CAS 133-32-4) is primarily used in agriculture and horticulture as a plant growth regulator to promote adventitious root formation in cuttings and support the establishment of young plants; it is commonly formulated as a rooting hormone for propagation of ornamentals, fruit trees, and other crops. It is also employed in plant tissue culture media to enhance rooting and regeneration efficiency. In research and development, it serves as a standard auxin analog for studying root development and plant physiology. As an intermediate in organic synthesis, it can be used in the preparation of related auxin compounds for industrial or laboratory use. It may also appear in nursery formulations for propagation services. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.96
    methanol 14.11
    isopropanol 3.26
    water 1.08
    ethyl acetate 2.22
    n-propanol 4.7
    acetone 5.19
    n-butanol 4.47
    acetonitrile 0.49
    DMF 25.62
    toluene 0.12
    isobutanol 5.08
    1,4-dioxane 2.52
    methyl acetate 3.16
    THF 15.25
    2-butanone 7.45
    n-pentanol 8.5
    sec-butanol 5.75
    n-hexane 0.07
    ethylene glycol 19.01
    NMP 47.77
    cyclohexane 0.01
    DMSO 25.5
    n-butyl acetate 6.26
    n-octanol 1.44
    chloroform 0.5
    n-propyl acetate 5.57
    acetic acid 20.82
    dichloromethane 0.54
    cyclohexanone 7.25
    propylene glycol 23.04
    isopropyl acetate 2.81
    DMAc 97.24
    2-ethoxyethanol 76.38
    isopentanol 8.96
    n-heptane 0.05
    ethyl formate 2.96
    1,2-dichloroethane 0.63
    n-hexanol 7.19
    2-methoxyethanol 67.78
    isobutyl acetate 5.19
    tetrachloromethane 0.22
    n-pentyl acetate 4.45
    transcutol 118.29
    n-heptanol 4.06
    ethylbenzene 0.36
    MIBK 6.37
    2-propoxyethanol 49.64
    tert-butanol 8.33
    MTBE 2.91
    2-butoxyethanol 24.83
    propionic acid 10.87
    o-xylene 0.27
    formic acid 46.15
    diethyl ether 0.88
    m-xylene 0.28
    p-xylene 0.64
    chlorobenzene 0.34
    dimethyl carbonate 4.47
    n-octane 0.03
    formamide 65.74
    cyclopentanone 15.77
    2-pentanone 4.65
    anisole 3.31
    cyclopentyl methyl ether 2.72
    gamma-butyrolactone 21.03
    1-methoxy-2-propanol 38.49
    pyridine 1.74
    3-pentanone 3.08
    furfural 24.7
    n-dodecane 0.04
    diethylene glycol 73.15
    diisopropyl ether 0.69
    tert-amyl alcohol 13.53
    acetylacetone 9.99
    n-hexadecane 0.05
    acetophenone 6.85
    methyl propionate 4.02
    isopentyl acetate 9.98
    trichloroethylene 1.81
    n-nonanol 1.9
    cyclohexanol 2.16
    benzyl alcohol 7.32
    2-ethylhexanol 4.24
    isooctanol 4.52
    dipropyl ether 1.71
    1,2-dichlorobenzene 0.8
    ethyl lactate 13.66
    propylene carbonate 10.89
    n-methylformamide 14.15
    2-pentanol 2.95
    n-pentane 0.02
    1-propoxy-2-propanol 25.85
    1-methoxy-2-propyl acetate 15.52
    2-(2-methoxypropoxy) propanol 37.31
    mesitylene 0.29
    ε-caprolactone 11.27
    p-cymene 0.72
    epichlorohydrin 14.19
    1,1,1-trichloroethane 0.48
    2-aminoethanol 32.21
    morpholine-4-carbaldehyde 44.44
    sulfolane 45.48
    2,2,4-trimethylpentane 0.1
    2-methyltetrahydrofuran 6.37
    n-hexyl acetate 4.57
    isooctane 0.07
    2-(2-butoxyethoxy)ethanol 42.69
    sec-butyl acetate 4.79
    tert-butyl acetate 6.75
    decalin 0.08
    glycerin 69.51
    diglyme 54.01
    acrylic acid 13.6
    isopropyl myristate 2.41
    n-butyric acid 10.28
    acetyl acetate 2.09
    di(2-ethylhexyl) phthalate 7.09
    ethyl propionate 4.61
    nitromethane 18.29
    1,2-diethoxyethane 7.89
    benzonitrile 2.1
    trioctyl phosphate 4.08
    1-bromopropane 0.26
    gamma-valerolactone 35.3
    n-decanol 1.61
    triethyl phosphate 6.13
    4-methyl-2-pentanol 4.32
    propionitrile 0.76
    vinylene carbonate 6.84
    1,1,2-trichlorotrifluoroethane 30.44
    DMS 8.81
    cumene 0.64
    2-octanol 1.93
    2-hexanone 8.61
    octyl acetate 3.23
    limonene 0.84
    1,2-dimethoxyethane 38.35
    ethyl orthosilicate 5.64
    tributyl phosphate 5.33
    diacetone alcohol 24.71
    N,N-dimethylaniline 3.46
    acrylonitrile 1.44
    aniline 1.04
    1,3-propanediol 29.95
    bromobenzene 0.22
    dibromomethane 0.27
    1,1,2,2-tetrachloroethane 1.73
    2-methyl-cyclohexyl acetate 7.82
    tetrabutyl urea 8.36
    diisobutyl methanol 2.39
    2-phenylethanol 7.38
    styrene 0.31
    dioctyl adipate 5.77
    dimethyl sulfate 13.98
    ethyl butyrate 5.0
    methyl lactate 16.26
    butyl lactate 13.38
    diethyl carbonate 4.22
    propanediol butyl ether 26.31
    triethyl orthoformate 5.88
    p-tert-butyltoluene 0.66
    methyl 4-tert-butylbenzoate 12.54
    morpholine 5.5
    tert-butylamine 2.08
    n-dodecanol 1.26
    dimethoxymethane 11.19
    ethylene carbonate 4.55
    cyrene 35.26
    2-ethoxyethyl acetate 12.06
    2-ethylhexyl acetate 6.53
    1,2,4-trichlorobenzene 1.27
    4-methylpyridine 1.52
    dibutyl ether 1.32
    2,6-dimethyl-4-heptanol 2.39
    DEF 7.93
    dimethyl isosorbide 43.52
    tetrachloroethylene 1.64
    eugenol 21.93
    triacetin 12.85
    span 80 20.0
    1,4-butanediol 27.6
    1,1-dichloroethane 0.3
    2-methyl-1-pentanol 14.34
    methyl formate 7.34
    2-methyl-1-butanol 9.56
    n-decane 0.06
    butyronitrile 1.12
    3,7-dimethyl-1-octanol 3.02
    1-chlorooctane 0.29
    1-chlorotetradecane 0.2
    n-nonane 0.04
    undecane 0.05
    tert-butylcyclohexane 0.13
    cyclooctane 0.01
    cyclopentanol 4.8
    tetrahydropyran 1.04
    tert-amyl methyl ether 4.46
    2,5,8-trioxanonane 47.12
    1-hexene 0.44
    2-isopropoxyethanol 43.78
    2,2,2-trifluoroethanol 12.69
    methyl butyrate 7.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction