Hydroxystearamide monoethanolamide

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  • Identifiers

    CAS number
    106-15-0

    Molecular formula
    C20H41NO3

    SMILES
    CCCCCCC(CCCCCCCCCCC(=O)NCCO)O

    Safety labels

  • Odor profile

    Fragrance
    Oily 33.98%
    Fresh 32.47%
    Savory 31.31%
    Odorless 30.34%
    Fatty 29.19%
    Fishy 29.13%
    Waxy 29.0%
    Citrus 28.67%
    Cooling 27.66%
    Meaty 26.78%

     

    Flavor
    Fatty 35.57%
    Odorless 34.32%
    Mild 34.05%
    Bland 30.0%
    Waxy 29.54%
    Oily 25.06%
    Faint 23.29%
    Fat 22.63%
    Slightly waxy 22.54%
    Bay oil 22.19%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.4

    pKa est.
    7.27 (neutral)

    Molecular weight
    343.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    491°C

    Flash point

    • 219.35 ˚C est.

  • Synonyms

    • 12-Hydroxy-N-(2-hydroxyethyl)octadecanamide
    • Octadecanamide, 12-hydroxy-N-(2-hydroxyethyl)-
    • Paricin 220
    • 106-15-0
    • Paracin 220
    • Hydroxystearamide MEA
    • Hydroxystearic acid monoethanolamide
    • 12-Hydroxy-N-(2-hydroxyethyl)octadecan-1-amide
    • 12-Hydroxy-N-(2-hydroxyethyl)stearamide
    • hydroxystearamide monoethanolamide
    • Stearamide, 12-hydroxy-N-(2-hydroxyethyl)-
    • EINECS 203-367-7
    • NSC 58333
    • NSC-58333
    • DTXSID10861720
    • HYDROXYSTEARAMIDE MONOETHANOLAMINE
    • n-(2-hydroxyethyl)-12-hydroxystearamide
    • 12-HYDROXY-2-N-(2-HYDROXYETHYL) STEARAMIDE
    • RefChem:789570
    • DTXCID00810606
    • (+-)-HYDROXYSTEARAMIDE MEA
    • HYDROXYSTEARAMIDE MEA [INCI]
    • HYDROXYSTEARAMIDE MEA, (+-)-
    • 3688201800
    • UNII-3688201800
    • NCIOpen2_007940
    • SCHEMBL167984
    • OZSKVMIBRHDIET-UHFFFAOYSA-N
    • NSC58333
    • (+/-)-HYDROXYSTEARAMIDE MEA
    • HYDROXYSTEARAMIDE MEA, (+/-)-
    • DB-277266
    • NS00013765
    • Q27231268
    • 106-15-0

  • Applications

    Hydroxystearamide monoethanolamide (CAS 106-15-0) is commonly used as a thickener and rheology modifier in cosmetic formulations, where it also functions as an emulsifier and conditioning agent in creams and lotions. It is also employed in household and professional cleaning products as a surfactant and foam stabilizer. In coatings and inks, the compound serves as a rheology modifier and thickener for waterborne systems. In polymer and plastics processing, it can act as a processing aid and lubricity additive to improve flow and handling. It may also be used as an intermediate or building block in specialty amide chemistries used in various industrial formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 11.69
    methanol 29.74
    isopropanol 8.42
    water 0.08
    ethyl acetate 18.01
    n-propanol 11.3
    acetone 20.62
    n-butanol 12.97
    acetonitrile 5.07
    DMF 67.58
    toluene 6.51
    isobutanol 10.53
    1,4-dioxane 34.77
    methyl acetate 13.77
    THF 140.53
    2-butanone 22.5
    n-pentanol 13.47
    sec-butanol 11.23
    n-hexane 1.09
    ethylene glycol 2.39
    NMP 162.86
    cyclohexane 4.11
    DMSO 199.59
    n-butyl acetate 34.69
    n-octanol 17.35
    chloroform 54.43
    n-propyl acetate 40.11
    acetic acid 30.74
    dichloromethane 54.28
    cyclohexanone 112.4
    propylene glycol 6.82
    isopropyl acetate 25.89
    DMAc 152.99
    2-ethoxyethanol 45.72
    isopentanol 19.06
    n-heptane 1.44
    ethyl formate 17.37
    1,2-dichloroethane 38.99
    n-hexanol 12.75
    2-methoxyethanol 50.28
    isobutyl acetate 29.7
    tetrachloromethane 12.24
    n-pentyl acetate 56.7
    transcutol 292.06
    n-heptanol 16.38
    ethylbenzene 7.23
    MIBK 34.16
    2-propoxyethanol 45.17
    tert-butanol 21.59
    MTBE 19.83
    2-butoxyethanol 59.6
    propionic acid 19.66
    o-xylene 9.73
    formic acid 13.71
    diethyl ether 8.58
    m-xylene 7.69
    p-xylene 10.29
    chlorobenzene 14.69
    dimethyl carbonate 10.25
    n-octane 0.99
    formamide 20.45
    cyclopentanone 115.08
    2-pentanone 26.39
    anisole 20.74
    cyclopentyl methyl ether 45.86
    gamma-butyrolactone 108.46
    1-methoxy-2-propanol 49.53
    pyridine 31.45
    3-pentanone 20.11
    furfural 97.54
    n-dodecane 0.77
    diethylene glycol 27.48
    diisopropyl ether 6.01
    tert-amyl alcohol 24.36
    acetylacetone 50.89
    n-hexadecane 0.9
    acetophenone 38.35
    methyl propionate 17.86
    isopentyl acetate 42.62
    trichloroethylene 76.4
    n-nonanol 17.45
    cyclohexanol 29.04
    benzyl alcohol 20.32
    2-ethylhexanol 13.79
    isooctanol 17.43
    dipropyl ether 16.76
    1,2-dichlorobenzene 22.44
    ethyl lactate 26.6
    propylene carbonate 65.78
    n-methylformamide 22.48
    2-pentanol 9.61
    n-pentane 0.63
    1-propoxy-2-propanol 44.89
    1-methoxy-2-propyl acetate 51.33
    2-(2-methoxypropoxy) propanol 58.65
    mesitylene 6.88
    ε-caprolactone 101.23
    p-cymene 8.22
    epichlorohydrin 89.6
    1,1,1-trichloroethane 35.64
    2-aminoethanol 9.38
    morpholine-4-carbaldehyde 107.31
    sulfolane 269.88
    2,2,4-trimethylpentane 1.76
    2-methyltetrahydrofuran 63.37
    n-hexyl acetate 54.48
    isooctane 0.95
    2-(2-butoxyethoxy)ethanol 84.92
    sec-butyl acetate 30.85
    tert-butyl acetate 50.15
    decalin 2.96
    glycerin 19.2
    diglyme 185.23
    acrylic acid 16.37
    isopropyl myristate 16.09
    n-butyric acid 44.78
    acetyl acetate 19.79
    di(2-ethylhexyl) phthalate 22.16
    ethyl propionate 26.74
    nitromethane 51.58
    1,2-diethoxyethane 48.7
    benzonitrile 20.78
    trioctyl phosphate 15.65
    1-bromopropane 13.76
    gamma-valerolactone 179.47
    n-decanol 10.56
    triethyl phosphate 27.72
    4-methyl-2-pentanol 10.93
    propionitrile 7.51
    vinylene carbonate 47.53
    1,1,2-trichlorotrifluoroethane 111.9
    DMS 27.53
    cumene 7.35
    2-octanol 12.33
    2-hexanone 35.02
    octyl acetate 21.56
    limonene 13.43
    1,2-dimethoxyethane 98.03
    ethyl orthosilicate 28.92
    tributyl phosphate 21.07
    diacetone alcohol 69.58
    N,N-dimethylaniline 20.52
    acrylonitrile 9.63
    aniline 12.82
    1,3-propanediol 18.4
    bromobenzene 14.89
    dibromomethane 29.31
    1,1,2,2-tetrachloroethane 84.34
    2-methyl-cyclohexyl acetate 41.59
    tetrabutyl urea 33.0
    diisobutyl methanol 11.14
    2-phenylethanol 20.26
    styrene 7.83
    dioctyl adipate 36.05
    dimethyl sulfate 38.23
    ethyl butyrate 36.5
    methyl lactate 22.83
    butyl lactate 54.41
    diethyl carbonate 21.11
    propanediol butyl ether 58.52
    triethyl orthoformate 37.62
    p-tert-butyltoluene 8.39
    methyl 4-tert-butylbenzoate 58.24
    morpholine 60.99
    tert-butylamine 10.61
    n-dodecanol 7.0
    dimethoxymethane 31.95
    ethylene carbonate 40.93
    cyrene 68.49
    2-ethoxyethyl acetate 68.96
    2-ethylhexyl acetate 33.26
    1,2,4-trichlorobenzene 30.72
    4-methylpyridine 28.68
    dibutyl ether 23.43
    2,6-dimethyl-4-heptanol 11.14
    DEF 54.21
    dimethyl isosorbide 116.11
    tetrachloroethylene 58.45
    eugenol 52.91
    triacetin 77.7
    span 80 51.98
    1,4-butanediol 8.26
    1,1-dichloroethane 22.09
    2-methyl-1-pentanol 18.93
    methyl formate 15.27
    2-methyl-1-butanol 16.82
    n-decane 1.7
    butyronitrile 10.56
    3,7-dimethyl-1-octanol 17.73
    1-chlorooctane 11.01
    1-chlorotetradecane 3.03
    n-nonane 1.48
    undecane 1.07
    tert-butylcyclohexane 2.39
    cyclooctane 1.27
    cyclopentanol 29.67
    tetrahydropyran 44.96
    tert-amyl methyl ether 22.5
    2,5,8-trioxanonane 108.73
    1-hexene 4.19
    2-isopropoxyethanol 35.97
    2,2,2-trifluoroethanol 17.83
    methyl butyrate 48.67

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction