Hydroxypropyl Methacrylate

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  • Identifiers

    CAS number
    27813-02-1

    Molecular formula
    C7H12O3

    SMILES
    CC(CO)OC(=O)C(=C)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 57.05%
    Caramellic 52.26%
    Buttery 42.39%
    Sweet 39.0%
    Creamy 31.24%
    Ethereal 30.88%
    Milky 27.27%
    Nutty 27.24%
    Burnt 26.12%
    Pungent 25.32%

     

    Flavor
    Fruity 71.0%
    Sweet 32.89%
    Creamy 32.09%
    Berry 28.52%
    Caramel 26.53%
    Buttery 25.53%
    Grape 23.18%
    Tropical 22.84%
    Butter 21.99%
    Dried berry 21.41%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.2

    pKa est.
    8.41 (weak base)

    Molecular weight
    144.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Melting point expt.

    • -89 °C

    Boiling point

    • Boiling point: 87 °C @ 0.67 kPa; Specific gravity: 1.028 @ 25 °C /2-Hydroxypropyl methacrylate/
    • Boiling point: 96 °C @ 1.3 kPa /2-Hydroxypropyl methacrylate/

    Flash point

    • 88.72 ˚C est.
    • 250 °F (USCG, 1999)
    • 250 °F (open cup)
    • 121 °C (Cleveland open cup)

    Solubility expt.

    • Limited solubility in water, sol in common organic solvents

  • Synonyms

    • Rocryl 410
    • 1,2-Propanediol, monomethacrylate
    • UKW89XAX2X
    • 1,2-Propanediol, 2-methyl, monomethacrylate
    • Methacrylic acid, monoester with 1,2-propanediol
    • 2-Propenoic acid, 2-methyl-, 2-hydroxymethylethyl ester
    • RefChem:923164
    • DTXSID5027936
    • DTXCID301778493
    • 248-666-3
    • 2-Propenoic acid, 2-methyl-, monoester with 1,2-propanediol
    • 27813-02-1
    • HPMA
    • Hydroxypropyl Methacrylate
    • Propylene glycol monomethacrylate
    • 2-Hydroxy-1-methylethyl methacrylate
    • 4664-49-7
    • 1-hydroxypropan-2-yl 2-methylprop-2-enoate
    • 1-hydroxypropan-2-yl methacrylate
    • 1-methyl-2-hydroxyethyl methacrylate
    • BC693EJ6V3
    • UNII-BC693EJ6V3
    • HSDB 597
    • EINECS 225-109-2
    • EINECS 248-666-3
    • UNII-UKW89XAX2X
    • Methacrylic acid, ester with 1,2-propanediol
    • Methacrylic acid, monoester with propane-1,2-diol
    • SCHEMBL204713
    • SCHEMBL377956
    • 1-hydroxy-2-propyl methacrylate
    • SCHEMBL10439985
    • DTXSID40867417
    • 2-hydroxy-1-methylethylmethacrylat
    • 2-Propenoic acid, 2-methyl-, 2-hydroxy-1-methylethyl ester
    • 2-(METHACRYLOYLOXY)PROPANOL
    • PROPANEDIOL, 2-METHACRYLATE
    • MFCD03703414
    • 2-HYDROXYISOPROPYL METHACRYLATE
    • AKOS006276999
    • 1,2-PROPANEDIOL, 2-METHACRYLATE
    • MSK161937-1000B
    • AS-62553
    • .BETA.-HYDROXYISOPROPYL METHACRYLATE
    • NS00001362
    • 1-oxidanylpropan-2-yl 2-methylprop-2-enoate
    • 2-Hydroxy-1-methylethyl 2-methyl-2-propenoate
    • D93504
    • EC 248-666-3
    • A819200
    • (2-hydroxy-1-methyl-ethyl) 2-methylprop-2-enoate
    • 2-methyl-2-propenoic acid 1-hydroxypropan-2-yl ester
    • Q27274591
    • METHACRYLIC ACID, 2-HYDROXY-1-METHYLETHYL ESTER
    • Hydroxypropyl methacrylate Solution in Acetone, 1000ug/mL
    • 4664-49-7

  • Applications

    Hydroxypropyl Methacrylate (CAS 27813-02-1) is a reactive vinyl monomer used to synthesize acrylic and polyacrylate resins with hydroxyl functionality. In industry, it is commonly employed as a comonomer or reactive diluent in coatings and UV-curable inks to improve adhesion and crosslinking, as a functional monomer in specialty adhesives to enhance bonding to diverse substrates, as a building block for hydrophilic or crosslinkable acrylic polymers used in coatings and electronics encapsulants, and as a component in plastics and packaging resins to tailor flexibility and chemical resistance.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 391.39
    methanol 572.87
    isopropanol 343.34
    water 28.92
    ethyl acetate 141.55
    n-propanol 304.24
    acetone 368.29
    n-butanol 258.05
    acetonitrile 233.73
    DMF 583.28
    toluene 47.91
    isobutanol 241.28
    1,4-dioxane 378.62
    methyl acetate 222.16
    THF 362.97
    2-butanone 273.65
    n-pentanol 239.25
    sec-butanol 341.83
    n-hexane 15.57
    ethylene glycol 208.81
    NMP 470.76
    cyclohexane 20.01
    DMSO 586.26
    n-butyl acetate 157.02
    n-octanol 147.81
    chloroform 285.43
    n-propyl acetate 133.49
    acetic acid 372.74
    dichloromethane 399.7
    cyclohexanone 287.08
    propylene glycol 217.97
    isopropyl acetate 94.82
    DMAc 574.75
    2-ethoxyethanol 376.17
    isopentanol 231.41
    n-heptane 16.74
    ethyl formate 213.64
    1,2-dichloroethane 224.07
    n-hexanol 197.12
    2-methoxyethanol 500.83
    isobutyl acetate 86.72
    tetrachloromethane 38.67
    n-pentyl acetate 108.31
    transcutol 438.94
    n-heptanol 125.77
    ethylbenzene 63.74
    MIBK 117.93
    2-propoxyethanol 288.72
    tert-butanol 419.09
    MTBE 229.61
    2-butoxyethanol 196.57
    propionic acid 249.08
    o-xylene 75.23
    formic acid 225.95
    diethyl ether 132.57
    m-xylene 54.93
    p-xylene 87.65
    chlorobenzene 91.49
    dimethyl carbonate 72.15
    n-octane 11.25
    formamide 256.25
    cyclopentanone 345.79
    2-pentanone 173.29
    anisole 158.71
    cyclopentyl methyl ether 144.22
    gamma-butyrolactone 388.6
    1-methoxy-2-propanol 329.37
    pyridine 184.75
    3-pentanone 128.29
    furfural 386.11
    n-dodecane 13.25
    diethylene glycol 260.08
    diisopropyl ether 45.11
    tert-amyl alcohol 401.66
    acetylacetone 195.92
    n-hexadecane 14.03
    acetophenone 188.56
    methyl propionate 142.13
    isopentyl acetate 154.46
    trichloroethylene 349.01
    n-nonanol 123.01
    cyclohexanol 194.98
    benzyl alcohol 184.43
    2-ethylhexanol 125.32
    isooctanol 107.44
    dipropyl ether 83.71
    1,2-dichlorobenzene 106.66
    ethyl lactate 114.67
    propylene carbonate 231.25
    n-methylformamide 300.62
    2-pentanol 188.11
    n-pentane 17.38
    1-propoxy-2-propanol 205.4
    1-methoxy-2-propyl acetate 143.4
    2-(2-methoxypropoxy) propanol 214.9
    mesitylene 43.74
    ε-caprolactone 265.91
    p-cymene 58.28
    epichlorohydrin 390.22
    1,1,1-trichloroethane 141.3
    2-aminoethanol 282.68
    morpholine-4-carbaldehyde 448.68
    sulfolane 505.74
    2,2,4-trimethylpentane 20.05
    2-methyltetrahydrofuran 285.64
    n-hexyl acetate 168.39
    isooctane 12.91
    2-(2-butoxyethoxy)ethanol 244.94
    sec-butyl acetate 87.17
    tert-butyl acetate 123.55
    decalin 20.24
    glycerin 274.67
    diglyme 392.25
    acrylic acid 238.91
    isopropyl myristate 75.7
    n-butyric acid 238.85
    acetyl acetate 96.56
    di(2-ethylhexyl) phthalate 95.18
    ethyl propionate 105.29
    nitromethane 503.11
    1,2-diethoxyethane 154.91
    benzonitrile 168.68
    trioctyl phosphate 78.06
    1-bromopropane 115.4
    gamma-valerolactone 431.09
    n-decanol 98.74
    triethyl phosphate 72.38
    4-methyl-2-pentanol 108.99
    propionitrile 161.3
    vinylene carbonate 226.11
    1,1,2-trichlorotrifluoroethane 314.66
    DMS 110.4
    cumene 61.7
    2-octanol 100.36
    2-hexanone 162.28
    octyl acetate 109.63
    limonene 80.55
    1,2-dimethoxyethane 456.18
    ethyl orthosilicate 65.97
    tributyl phosphate 85.14
    diacetone alcohol 214.86
    N,N-dimethylaniline 140.26
    acrylonitrile 225.77
    aniline 108.56
    1,3-propanediol 299.68
    bromobenzene 77.69
    dibromomethane 220.7
    1,1,2,2-tetrachloroethane 297.21
    2-methyl-cyclohexyl acetate 125.0
    tetrabutyl urea 115.28
    diisobutyl methanol 76.24
    2-phenylethanol 150.61
    styrene 68.06
    dioctyl adipate 124.16
    dimethyl sulfate 151.94
    ethyl butyrate 120.93
    methyl lactate 129.94
    butyl lactate 118.75
    diethyl carbonate 85.56
    propanediol butyl ether 206.58
    triethyl orthoformate 83.6
    p-tert-butyltoluene 56.34
    methyl 4-tert-butylbenzoate 178.13
    morpholine 369.23
    tert-butylamine 236.41
    n-dodecanol 79.04
    dimethoxymethane 241.05
    ethylene carbonate 169.53
    cyrene 222.7
    2-ethoxyethyl acetate 139.88
    2-ethylhexyl acetate 108.67
    1,2,4-trichlorobenzene 143.87
    4-methylpyridine 204.42
    dibutyl ether 93.11
    2,6-dimethyl-4-heptanol 76.24
    DEF 249.15
    dimethyl isosorbide 265.22
    tetrachloroethylene 186.0
    eugenol 186.15
    triacetin 172.05
    span 80 179.06
    1,4-butanediol 202.13
    1,1-dichloroethane 190.34
    2-methyl-1-pentanol 229.73
    methyl formate 267.81
    2-methyl-1-butanol 232.87
    n-decane 18.3
    butyronitrile 171.8
    3,7-dimethyl-1-octanol 138.55
    1-chlorooctane 69.25
    1-chlorotetradecane 32.91
    n-nonane 17.07
    undecane 15.14
    tert-butylcyclohexane 22.09
    cyclooctane 9.66
    cyclopentanol 245.29
    tetrahydropyran 222.71
    tert-amyl methyl ether 189.67
    2,5,8-trioxanonane 308.8
    1-hexene 57.22
    2-isopropoxyethanol 255.9
    2,2,2-trifluoroethanol 147.16
    methyl butyrate 178.88

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction