Hydroxypropyl bispalmitamide monoethanolamide

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  • Identifiers

    CAS number
    211184-47-3

    Molecular formula
    C39H78N2O5

    SMILES
    CCCCCCCCCCCCCCCC(=O)N(CCO)CC(CN(CCO)C(=O)CCCCCCCCCCCCCCC)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 43.71%
    Odorless 35.76%
    Oily 33.0%
    Fatty 29.09%
    Woody 28.95%
    Fresh 26.67%
    Savory 26.15%
    Fishy 26.06%
    Animal 23.61%
    Cooling 22.62%

     

    Flavor
    Bland 41.28%
    Odorless 37.2%
    Mild 33.42%
    Faint 25.02%
    Waxy 22.19%
    Slightly waxy 21.7%
    Fatty 21.19%
    Delicate 20.45%
    Bay oil 20.35%
    Sweet-like 19.68%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    11.9

    pKa est.
    9.07 (weak base)

    Molecular weight
    655.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1375°C

    Flash point

    • 305.29 ˚C est.

  • Synonyms

    • 211184-47-3
    • Hydroxypropyl bispalmitamide monoethanolamide
    • Ceramide pc-104
    • EVX7NC9YVE
    • Hydroxypropyl bispalmitamide MEA
    • Hydroxypropyl bispalmitamide monoethanolamine
    • DTXSID20175345
    • Hexadecanamide, N,N'-(2-hydroxy-1,3-propanediyl)bis(N-(2-hydroxyethyl)-
    • Hexadecanamide, N,N'-(2-hydroxy-1,3-propanediyl)bis[N-(2-hydroxyethyl)-
    • RefChem:789546
    • DTXCID9097836
    • HYDROXYPROPYL BISPALMITAMIDE MEA [INCI]
    • 606-708-1
    • UNII-EVX7NC9YVE
    • N,N'-(2-Hydroxypropane-1,3-diyl)bis(N-(2-hydroxyethyl)palmitamide)
    • N-[3-[hexadecanoyl(2-hydroxyethyl)amino]-2-hydroxypropyl]-N-(2-hydroxyethyl)hexadecanamide
    • SCHEMBL5063320
    • MFCD16876359
    • PC 104
    • AC-38208
    • SY311741
    • NS00026789
    • Q27277386
    • 1,3-bis(N-(2-hydroxyethyl)-palmitoylamino)-2-hydroxypropane
    • (1,3-bis-(N-(2-hydroxyethyl)-palmitoyl-amino)-2-hydroxypropane
    • N,N'-(2-Hydroxypropane-1,3-diyl)bis[N-(2-hydroxyethyl)hexadecanamide]
    • N,N inverted exclamation mark -(2-Hydroxypropane-1,3-diyl)bis[N-(2-hydroxyethyl)palmitamide]
    • 211184-47-3

  • Applications

    Hydroxypropyl bispalmitamide monoethanolamide (CAS 211184-47-3) is a nonionic surfactant and emulsifier derivative of palmitic acid, commonly used as an emulsifier, surfactant, and conditioning/softening agent in cosmetics and personal care formulations, where it can function as a mild emollient and help stabilize oil-water emulsions. It is also employed in household cleaning products as a surfactant and wetting agent to improve soil removal and formulation stability. In polymers and plastics processing, it can act as a processing aid and lubricant, enhancing dispersion of oils and improving processing characteristics. In coatings and inks, it serves as an emulsifier/compatibilizer to stabilize emulsions and improve film formation and uniformity. Additionally, it may be used as an additive in adhesives and sealants to improve compatibility and performance of the formulation; its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.06
    methanol 7.6
    isopropanol 3.12
    water 0.44
    ethyl acetate 22.36
    n-propanol 6.07
    acetone 16.85
    n-butanol 5.23
    acetonitrile 6.44
    DMF 55.61
    toluene 9.3
    isobutanol 4.79
    1,4-dioxane 23.93
    methyl acetate 19.78
    THF 56.24
    2-butanone 24.27
    n-pentanol 5.76
    sec-butanol 6.17
    n-hexane 1.17
    ethylene glycol 1.5
    NMP 201.75
    cyclohexane 2.67
    DMSO 57.7
    n-butyl acetate 16.0
    n-octanol 6.46
    chloroform 56.03
    n-propyl acetate 21.4
    acetic acid 30.66
    dichloromethane 57.59
    cyclohexanone 66.25
    propylene glycol 3.09
    isopropyl acetate 17.78
    DMAc 158.47
    2-ethoxyethanol 18.11
    isopentanol 5.06
    n-heptane 1.01
    ethyl formate 17.8
    1,2-dichloroethane 32.76
    n-hexanol 4.11
    2-methoxyethanol 18.65
    isobutyl acetate 11.45
    tetrachloromethane 14.17
    n-pentyl acetate 29.9
    transcutol 75.49
    n-heptanol 6.32
    ethylbenzene 6.49
    MIBK 12.78
    2-propoxyethanol 15.95
    tert-butanol 4.76
    MTBE 8.99
    2-butoxyethanol 24.3
    propionic acid 19.23
    o-xylene 10.54
    formic acid 14.28
    diethyl ether 7.09
    m-xylene 6.87
    p-xylene 8.86
    chlorobenzene 16.52
    dimethyl carbonate 18.69
    n-octane 0.73
    formamide 20.36
    cyclopentanone 77.47
    2-pentanone 19.36
    anisole 12.4
    cyclopentyl methyl ether 28.87
    gamma-butyrolactone 106.39
    1-methoxy-2-propanol 16.06
    pyridine 32.17
    3-pentanone 22.53
    furfural 87.01
    n-dodecane 0.43
    diethylene glycol 8.78
    diisopropyl ether 3.26
    tert-amyl alcohol 8.68
    acetylacetone 34.45
    n-hexadecane 0.49
    acetophenone 26.98
    methyl propionate 26.54
    isopentyl acetate 15.71
    trichloroethylene 73.44
    n-nonanol 6.96
    cyclohexanol 12.15
    benzyl alcohol 11.11
    2-ethylhexanol 4.63
    isooctanol 5.84
    dipropyl ether 8.45
    1,2-dichlorobenzene 22.81
    ethyl lactate 17.13
    propylene carbonate 63.94
    n-methylformamide 24.0
    2-pentanol 4.31
    n-pentane 0.85
    1-propoxy-2-propanol 15.75
    1-methoxy-2-propyl acetate 24.48
    2-(2-methoxypropoxy) propanol 24.71
    mesitylene 4.46
    ε-caprolactone 80.93
    p-cymene 4.71
    epichlorohydrin 68.1
    1,1,1-trichloroethane 38.19
    2-aminoethanol 4.26
    morpholine-4-carbaldehyde 91.36
    sulfolane 203.63
    2,2,4-trimethylpentane 1.08
    2-methyltetrahydrofuran 39.4
    n-hexyl acetate 25.04
    isooctane 0.36
    2-(2-butoxyethoxy)ethanol 28.52
    sec-butyl acetate 16.5
    tert-butyl acetate 20.79
    decalin 1.71
    glycerin 7.59
    diglyme 67.75
    acrylic acid 19.49
    isopropyl myristate 6.97
    n-butyric acid 27.25
    acetyl acetate 22.3
    di(2-ethylhexyl) phthalate 10.93
    ethyl propionate 21.92
    nitromethane 56.31
    1,2-diethoxyethane 22.59
    benzonitrile 13.9
    trioctyl phosphate 7.27
    1-bromopropane 13.3
    gamma-valerolactone 129.55
    n-decanol 4.13
    triethyl phosphate 18.47
    4-methyl-2-pentanol 3.05
    propionitrile 7.64
    vinylene carbonate 55.9
    1,1,2-trichlorotrifluoroethane 79.6
    DMS 25.55
    cumene 4.88
    2-octanol 5.19
    2-hexanone 18.84
    octyl acetate 10.85
    limonene 7.38
    1,2-dimethoxyethane 34.49
    ethyl orthosilicate 16.18
    tributyl phosphate 10.29
    diacetone alcohol 24.03
    N,N-dimethylaniline 12.99
    acrylonitrile 11.08
    aniline 11.69
    1,3-propanediol 6.09
    bromobenzene 16.87
    dibromomethane 29.26
    1,1,2,2-tetrachloroethane 69.14
    2-methyl-cyclohexyl acetate 18.47
    tetrabutyl urea 16.66
    diisobutyl methanol 2.89
    2-phenylethanol 8.7
    styrene 6.91
    dioctyl adipate 16.48
    dimethyl sulfate 59.27
    ethyl butyrate 19.74
    methyl lactate 20.79
    butyl lactate 29.15
    diethyl carbonate 14.7
    propanediol butyl ether 19.78
    triethyl orthoformate 20.17
    p-tert-butyltoluene 4.44
    methyl 4-tert-butylbenzoate 34.21
    morpholine 33.81
    tert-butylamine 2.97
    n-dodecanol 2.64
    dimethoxymethane 23.77
    ethylene carbonate 43.68
    cyrene 39.39
    2-ethoxyethyl acetate 43.96
    2-ethylhexyl acetate 14.44
    1,2,4-trichlorobenzene 32.05
    4-methylpyridine 27.86
    dibutyl ether 9.37
    2,6-dimethyl-4-heptanol 2.89
    DEF 40.48
    dimethyl isosorbide 52.34
    tetrachloroethylene 47.67
    eugenol 27.15
    triacetin 47.27
    span 80 20.15
    1,4-butanediol 3.73
    1,1-dichloroethane 24.14
    2-methyl-1-pentanol 6.81
    methyl formate 20.86
    2-methyl-1-butanol 6.71
    n-decane 1.03
    butyronitrile 7.12
    3,7-dimethyl-1-octanol 5.55
    1-chlorooctane 5.43
    1-chlorotetradecane 1.56
    n-nonane 0.93
    undecane 0.62
    tert-butylcyclohexane 1.18
    cyclooctane 1.02
    cyclopentanol 14.96
    tetrahydropyran 25.65
    tert-amyl methyl ether 12.81
    2,5,8-trioxanonane 38.79
    1-hexene 3.53
    2-isopropoxyethanol 13.44
    2,2,2-trifluoroethanol 24.74
    methyl butyrate 31.15

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction