Hydroxyethylethylenediaminetriacetic acid

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  • Identifiers

    CAS number
    139-89-9

    Molecular formula
    C10H18N2O7

    SMILES
    C(CN(CC(=O)O)CC(=O)O)N(CCO)CC(=O)O

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 63.3%
    Sweet 40.64%
    Savory 28.21%
    Fishy 23.58%
    Alcoholic 20.68%
    Meaty 18.63%
    Oily 16.0%
    Clean 15.46%
    Milky 14.98%
    Cooked 14.06%

     

    Flavor
    Odorless 69.26%
    Mild 38.24%
    Bland 33.51%
    Bitter 30.28%
    Very mild 25.47%
    Sweet-like 23.73%
    Yeast 23.38%
    Faint 22.06%
    Bay oil 19.63%
    Cultured dairy 19.48%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -6.2

    pKa est.
    4.36 (weak acid)

    Molecular weight
    278.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    507°C

    Melting point expt.

    • 288 °C (hydate)
    • 159 °C

    Flash point

    • 293.86 ˚C est.
    • Flash point: 100 °C (closed cup)

    Solubility expt.

    • Insoluble in most organic solvents
    • In water, 480 g/L at 20 °C
    • SOL IN WATER AND METHANOL

  • Synonyms

    • N-(2-Hydroxyethyl)ethylenediaminetriacetic acid
    • HEDTA
    • Heedta
    • Versenol
    • Versenol 120
    • (2-Hydroxyethyl)ethylenediaminetriacetic acid
    • Hydroxyethylethylenediaminetriacetic acid
    • Caswell No. 487B
    • N-(Hydroxyethyl)ethylenediaminetriacetic acid
    • 2-Hydroxyethylenediamine triacetate
    • HSDB 5651
    • EINECS 205-759-3
    • Glycine, N-[2-[bis(carboxymethyl)amino]ethyl]-N-(2-hydroxyethyl)-
    • EPA Pesticide Chemical Code 039108
    • BRN 1804795
    • UNII-R79J91U341
    • NSC-7341
    • (N-Hydroxyethylethylenedinitrilo)triacetic acid
    • n-Hydroxyethylethylenediamine-n,n',n'-triacetic acid
    • Hydroxyethyl ethylenediamine triacetic acid
    • N-Hydroxyethylethylenedinitrilotriacetic acid
    • N-(beta-Hydroxyethylethylenediamine)-N,N',N'-triacetic acid
    • DTXSID1059737
    • N-Hydroxy-N,N',N'-ethylenediaminetriacetic acid trisodium salt
    • Glycine, N-(2-(bis(carboxymethyl)amino)ethyl)-N-(2-hydroxyethyl)-
    • N-(2-(Bis(carboxymethyl)amino)ethyl)-N-(2-hydroxyethyl)glycine
    • n-{2-[bis(carboxymethyl)amino]ethyl}-n-(2-hydroxyethyl)glycine
    • n-hydroxyethyl ethylenediamine triacetic acid
    • N-(2-Hydroxyethyl)ethylenedinitrilotriacetic acid
    • HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID [HSDB]
    • VERSENOL [MI]
    • N-(.beta.-(Hydroxyethyl)ethylenediamine)-N,N',N'-triacetic acid
    • Trisodium hydroxyethyl ethylenediaminetriacetate
    • Trisodium salt of (hydroxyethyl)ethylenediamine
    • Hampol Crystals
    • HampOL acid
    • Versen01
    • Monaquest ICA120
    • Co-HEDTA
    • Dy-HEDTA
    • TbHED3A
    • Hampol 120
    • HEDTA [INCI]
    • RefChem:147178
    • DTXCID5034858
    • NHydroxyethylenediaminetriacetic acid
    • n(hydroxyethyl)ethylenediaminetriacetic acid
    • (2Hydroxyethyl)ethylenediaminetriacetic acid
    • (NHydroxyethylethylenedinitrilo)triacetic acid
    • N(2Hydroxyethyl)ethylenediaminetriacetic acid
    • Trisodium Nhydroxyethylethylenediaminetriacetate
    • Trisodium (2hydroxyethyl)ethylenediaminetriacetate
    • Trisodium N(hydroxyethyl)ethylenediaminetriacetate
    • Trisodium N(2hydroxyethyl)ethylenediaminetriacetate
    • N'(2Hydroxyethyl)ethylenediamineN,N,N'triacetic acid
    • N(Carboxymethyl)N'(2hydroxyethyl)N,N'ethylenediglycine
    • Trisodium NhydroxyethylethylenediamineN,N',N'triacetate
    • Glycine, N(carboxymethyl)N'(2hydroxyethyl)N,N'ethylenedi
    • N(betaHydroxyethylethylenediamine)N,N',N'triacetic acid
    • NHydroxyethylethylenediaminetriacetic acid trisodium salt
    • Trisodium salt Nhydroxyethylethylenediaminetriacetic acid
    • (2Hydroxyethyl)ethylenediaminetriacetic acid, trisodium salt
    • N(2(Bis(carboxymethyl)amino)ethyl)N(2hydroxyethyl)glycine
    • Trisodium N(2hydroxyethyl)ethylenediamineN,N',N'triacetate
    • Glycine, N(2(bis(carboxymethyl)amino)ethyl)N(2hydroxyethyl)
    • N(Hydroxyethyl)N,N',N'ethylenediaminetriacetic acid trisodium
    • N-(beta-(Hydroxyethyl)ethylenediamine)-N,N',N'-triacetic acid
    • N(2Hydroxyethyl)N,N',N'ethylenediaminetriacetic acid trisodium salt
    • N(Hydroxyethyl)N,N',N'ethylenediaminetriacetic acid trisodium salt
    • Glycine, N(2(bis(carboxymethyl)amino)ethyl)N(2hydroxyethyl), trisodium salt
    • Glycine, N(carboxymethyl)N'(2hydroxyethyl)N,N'ethylenedi, trisodium salt
    • N(2(Bis(carboxymethyl)amino)ethyl)N(2hydroxyethyl)glycine trisodium salt
    • N(Carboxymethyl)N'(2hydroxyethyl)N,N'ethylenediglycine trisodium salt
    • 139-89-9
    • 4-04-00-02449 (Beilstein Handbook Reference)
    • URDCARMUOSMFFI-UHFFFAOYSA-N
    • 150-39-0
    • Detarol
    • CHEL DM acid
    • N-(2-Hydroxyethyl)ethylenediamine-N,N',N'-triacetic acid
    • Hamp-ol acid
    • Oxyethylethylenediaminetriacetic acid
    • N-Hydroxyethylenediaminetriacetic acid
    • Hydroxyethylethylenediaminotriacetic acid
    • (Hydroxyethyl)ethylenediaminetriacetic acid
    • NSC 7341
    • 2-[2-[bis(carboxymethyl)amino]ethyl-(2-hydroxyethyl)amino]acetic acid
    • MFCD00004294
    • 2,2-((2-((Carboxymethyl)(2-hydroxyethyl)amino)ethyl)azanediyl)diacetic acid
    • EDTA-OH
    • N-(Carboxymethyl)-N'-(2-hydroxyethyl)-N,N'-ethylenediglycine
    • 2,2'-((2-((carboxymethyl)(2-hydroxyethyl)amino)ethyl)azanediyl)diacetic acid
    • N'-(2-Hydroxyethyl)ethylenediamine-N,N,N'-triacetic acid
    • Glycine, N-(carboxymethyl)-N'-(2-hydroxyethyl)-N,N'-ethylenedi-
    • R79J91U341
    • 2-({2-[bis(carboxymethyl)amino]ethyl}(2-hydroxyethyl)amino)acetic acid
    • Glycine,N'-ethylenedi-
    • MLS000069405
    • SCHEMBL143335
    • orb1962276
    • WLN: QV1N2Q2N1VQ1VQ
    • CHEMBL1620428
    • Gadoxetate Disodium Impurity 21
    • NSC7341
    • N-Carboxymethyl-N'-(2-hydroxyethyl)-N,N'-ethylenediglycine
    • SBB058251
    • AKOS017345022
    • CS-W014567
    • HY-W013851
    • AC-37697
    • AS-17818
    • SMR000059065
    • SY012052
    • H0243
    • NS00008606
    • ST50308215
    • D70290
    • [(N-Hydroxyethyl)ethylenedinitrilo]triacetic acid
    • EN300-7393828
    • F492380
    • N-(Hydroxyethyl)ethylenediamine-N,N'-triacetic acid
    • N-(2-Hydroxyethyl)ethylenediamine-N,N'-triacetic acid
    • Q23014132
    • N'-(2-Hydroxyethyl)ethylenediamine-N,N'-triacetic acid
    • N-(2-(Hydroxyethyl)ethylenediamine-N,N'-triacetic acid
    • N-(Hydroxyethyl)ethylenediamine-N,N',N'-triacetic acid
    • N-Hydroxy-N,N'-ethylenediaminetriacetic acid trisodium salt
    • 139-89-9

  • Applications

    Hydroxyethylethylenediaminetriacetic acid is employed as a chelating agent to complex multivalent metal ions, helping to sequester calcium and magnesium and inhibit metal-catalyzed degradation in industrial and household cleaning formulations; it is used as a stabilizer and chelating additive in cosmetics and personal care products to improve formulation stability and color retention; in water treatment and cooling/boiler systems, it functions as a corrosion inhibitor and scale-control agent; in polymer/plastics processing, it acts as a chelating and dispersing additive to control trace metal contamination during processing; and in coatings, inks, and related formulations it improves bath stability and pigment dispersion while reducing metal-catalyzed aging.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.08
    methanol 0.92
    isopropanol 0.02
    water 16.55
    ethyl acetate 0.01
    n-propanol 0.06
    acetone 0.01
    n-butanol 0.03
    acetonitrile 0.01
    DMF 8.11
    toluene 0.01
    isobutanol 0.03
    1,4-dioxane 0.01
    methyl acetate 0.02
    THF 0.04
    2-butanone 0.03
    n-pentanol 0.01
    sec-butanol 0.03
    n-hexane 0.0
    ethylene glycol 1.73
    NMP 28.44
    cyclohexane 0.0
    DMSO 13.04
    n-butyl acetate 0.02
    n-octanol 0.01
    chloroform 0.01
    n-propyl acetate 0.01
    acetic acid 0.65
    dichloromethane 0.02
    cyclohexanone 0.1
    propylene glycol 1.11
    isopropyl acetate 0.01
    DMAc 7.47
    2-ethoxyethanol 0.17
    isopentanol 0.02
    n-heptane 0.01
    ethyl formate 0.05
    1,2-dichloroethane 0.02
    n-hexanol 0.03
    2-methoxyethanol 0.98
    isobutyl acetate 0.01
    tetrachloromethane 0.01
    n-pentyl acetate 0.01
    transcutol 0.44
    n-heptanol 0.03
    ethylbenzene 0.01
    MIBK 0.02
    2-propoxyethanol 0.33
    tert-butanol 0.02
    MTBE 0.01
    2-butoxyethanol 0.16
    propionic acid 0.37
    o-xylene 0.05
    formic acid 18.52
    diethyl ether 0.01
    m-xylene 0.03
    p-xylene 0.01
    chlorobenzene 0.01
    dimethyl carbonate 0.14
    n-octane 0.0
    formamide 10.28
    cyclopentanone 0.17
    2-pentanone 0.02
    anisole 0.02
    cyclopentyl methyl ether 0.06
    gamma-butyrolactone 0.41
    1-methoxy-2-propanol 0.54
    pyridine 0.06
    3-pentanone 0.05
    furfural 0.97
    n-dodecane 0.0
    diethylene glycol 1.02
    diisopropyl ether 0.0
    tert-amyl alcohol 0.05
    acetylacetone 0.04
    n-hexadecane 0.0
    acetophenone 0.07
    methyl propionate 0.1
    isopentyl acetate 0.02
    trichloroethylene 0.04
    n-nonanol 0.01
    cyclohexanol 0.05
    benzyl alcohol 0.05
    2-ethylhexanol 0.03
    isooctanol 0.02
    dipropyl ether 0.03
    1,2-dichlorobenzene 0.01
    ethyl lactate 0.17
    propylene carbonate 0.15
    n-methylformamide 3.0
    2-pentanol 0.02
    n-pentane 0.0
    1-propoxy-2-propanol 0.26
    1-methoxy-2-propyl acetate 0.12
    2-(2-methoxypropoxy) propanol 0.31
    mesitylene 0.02
    ε-caprolactone 0.16
    p-cymene 0.03
    epichlorohydrin 0.08
    1,1,1-trichloroethane 0.01
    2-aminoethanol 1.75
    morpholine-4-carbaldehyde 3.01
    sulfolane 7.05
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 0.02
    n-hexyl acetate 0.02
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 0.21
    sec-butyl acetate 0.01
    tert-butyl acetate 0.02
    decalin 0.0
    glycerin 9.79
    diglyme 0.36
    acrylic acid 1.1
    isopropyl myristate 0.01
    n-butyric acid 0.16
    acetyl acetate 0.01
    di(2-ethylhexyl) phthalate 0.03
    ethyl propionate 0.03
    nitromethane 0.47
    1,2-diethoxyethane 0.01
    benzonitrile 0.02
    trioctyl phosphate 0.03
    1-bromopropane 0.01
    gamma-valerolactone 0.69
    n-decanol 0.01
    triethyl phosphate 0.1
    4-methyl-2-pentanol 0.01
    propionitrile 0.02
    vinylene carbonate 0.21
    1,1,2-trichlorotrifluoroethane 1.83
    DMS 0.06
    cumene 0.01
    2-octanol 0.01
    2-hexanone 0.01
    octyl acetate 0.01
    limonene 0.04
    1,2-dimethoxyethane 0.09
    ethyl orthosilicate 0.08
    tributyl phosphate 0.04
    diacetone alcohol 0.17
    N,N-dimethylaniline 0.08
    acrylonitrile 0.07
    aniline 0.05
    1,3-propanediol 0.41
    bromobenzene 0.0
    dibromomethane 0.01
    1,1,2,2-tetrachloroethane 0.05
    2-methyl-cyclohexyl acetate 0.05
    tetrabutyl urea 0.1
    diisobutyl methanol 0.02
    2-phenylethanol 0.05
    styrene 0.01
    dioctyl adipate 0.02
    dimethyl sulfate 1.42
    ethyl butyrate 0.04
    methyl lactate 1.01
    butyl lactate 0.14
    diethyl carbonate 0.03
    propanediol butyl ether 0.28
    triethyl orthoformate 0.06
    p-tert-butyltoluene 0.03
    methyl 4-tert-butylbenzoate 0.19
    morpholine 0.05
    tert-butylamine 0.01
    n-dodecanol 0.01
    dimethoxymethane 0.3
    ethylene carbonate 0.08
    cyrene 1.08
    2-ethoxyethyl acetate 0.02
    2-ethylhexyl acetate 0.02
    1,2,4-trichlorobenzene 0.02
    4-methylpyridine 0.05
    dibutyl ether 0.01
    2,6-dimethyl-4-heptanol 0.02
    DEF 0.37
    dimethyl isosorbide 0.63
    tetrachloroethylene 0.06
    eugenol 0.21
    triacetin 0.08
    span 80 0.22
    1,4-butanediol 0.1
    1,1-dichloroethane 0.0
    2-methyl-1-pentanol 0.01
    methyl formate 0.78
    2-methyl-1-butanol 0.04
    n-decane 0.0
    butyronitrile 0.01
    3,7-dimethyl-1-octanol 0.01
    1-chlorooctane 0.0
    1-chlorotetradecane 0.0
    n-nonane 0.0
    undecane 0.0
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 0.05
    tetrahydropyran 0.01
    tert-amyl methyl ether 0.02
    2,5,8-trioxanonane 0.31
    1-hexene 0.01
    2-isopropoxyethanol 0.05
    2,2,2-trifluoroethanol 0.86
    methyl butyrate 0.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction