Hydroxyethyl Urea

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  • Identifiers

    CAS number
    2078-71-9

    Molecular formula
    C3H8N2O2

    SMILES
    C(CO)NC(=O)N

    Safety labels

  • Odor profile

    Fragrance
    Odorless 63.1%
    Fishy 40.58%
    Savory 32.69%
    Meaty 27.46%
    Sweet 25.76%
    Cheesy 20.68%
    Cooling 18.15%
    Pungent 17.46%
    Ripe 16.95%
    Cooked 16.89%

     

    Flavor
    Odorless 67.64%
    Mild 28.03%
    Sweet-like 22.9%
    Bland 22.27%
    Yeast 21.93%
    Very mild 21.71%
    Sour 21.19%
    Faint 20.86%
    Acidic 20.31%
    Very slight 20.21%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.7

    pKa est.
    8.19 (weak base)

    Molecular weight
    104.11 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    361°C

    Flash point

    • 166.28 ˚C est.

  • Synonyms

    • 2078-71-9
    • (2-Hydroxyethyl)urea
    • Urea, (2-hydroxyethyl)-
    • Monoethanolurea
    • hydroxyethyl urea
    • Monoethylolurea
    • Urea, N-(hydroxyethyl)-
    • 1-Ethanolurea
    • 1320-51-0
    • hydroxyethylurea
    • N-(2-Hydroxyethyl)urea
    • (beta-Hydroxyethyl)urea
    • Urea, (hydroxyethyl)-
    • (Hydroxyethyl)urea
    • N-(beta-Hydroxyethyl)urea
    • HYDROVANCE
    • MBQ7DDQ7AR
    • NSC 1127
    • N-(.beta.-Hydroxyethyl)urea
    • BRN 1098722
    • NSC-1127
    • EINECS 215-304-0
    • EC 215-304-0
    • DTXSID401315038
    • HYDROXYETHYL UREA [WHO-DD]
    • 4-04-00-01545 (Beilstein Handbook Reference)
    • UREA, N-(2-HYDROXYETHYL)-
    • RefChem:789476
    • DTXCID8030217
    • DTXSID4051663
    • HYDROXYETHYL UREA [INCI]
    • 215-304-0
    • 640-848-4
    • 2-Hydroxyethylurea
    • 1-(2-Hydroxyethyl)urea
    • MFCD00059080
    • N-(Hydroxyethyl)-urea
    • UNII-MBQ7DDQ7AR
    • NSC1127
    • n-2-hydroxyethylurea
    • (.beta.-Hydroxyethyl)urea
    • SCHEMBL27663
    • (2-Hydroxyethyl)urea, 95%
    • SCHEMBL1419079
    • SCHEMBL2448290
    • SCHEMBL5263719
    • SCHEMBL31404266
    • CLAHOZSYMRNIPY-UHFFFAOYSA-
    • AKOS001015414
    • CS-W011301
    • AS-10053
    • SY038945
    • H0700
    • NS00007137
    • EN300-266974
    • F319865
    • Q27283827
    • F1019-0075
    • InChI=1/C3H8N2O2/c4-3(7)5-1-2-6/h6H,1-2H2,(H3,4,5,7)
    • 1320-51-0

  • Applications

    Hydroxyethyl Urea (CAS 2078-71-9) is commonly used as a humectant and conditioning agent in cosmetics and personal care, helping to retain moisture and improve skin and hair feel; it is also evaluated for use in household and cleaning products as a moisture-retention additive and stabilizer in formulations; in coatings and inks, it can act as a humectant and process stabilizer to control drying and surface properties; in the plastics and polymer sector, it may serve as a processing aid or intermediate in polymer formulations; and in adhesives, it can function as a moisture-retaining additive or compatibility enhancer to improve bond stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.45
    methanol 32.74
    isopropanol 4.34
    water 604.78
    ethyl acetate 2.19
    n-propanol 5.76
    acetone 5.78
    n-butanol 3.79
    acetonitrile 4.27
    DMF 199.3
    toluene 0.45
    isobutanol 3.43
    1,4-dioxane 5.67
    methyl acetate 2.76
    THF 10.92
    2-butanone 2.48
    n-pentanol 2.21
    sec-butanol 2.99
    n-hexane 0.19
    ethylene glycol 56.63
    NMP 95.74
    cyclohexane 0.17
    DMSO 122.74
    n-butyl acetate 1.83
    n-octanol 1.37
    chloroform 1.44
    n-propyl acetate 1.4
    acetic acid 49.55
    dichloromethane 1.94
    cyclohexanone 6.56
    propylene glycol 37.93
    isopropyl acetate 1.29
    DMAc 91.41
    2-ethoxyethanol 16.8
    isopentanol 2.86
    n-heptane 0.22
    ethyl formate 16.37
    1,2-dichloroethane 1.3
    n-hexanol 2.25
    2-methoxyethanol 49.82
    isobutyl acetate 0.73
    tetrachloromethane 0.86
    n-pentyl acetate 1.42
    transcutol 11.06
    n-heptanol 1.75
    ethylbenzene 0.32
    MIBK 1.46
    2-propoxyethanol 12.46
    tert-butanol 4.74
    MTBE 1.09
    2-butoxyethanol 8.03
    propionic acid 14.13
    o-xylene 0.77
    formic acid 233.37
    diethyl ether 0.75
    m-xylene 0.63
    p-xylene 0.55
    chlorobenzene 0.68
    dimethyl carbonate 4.32
    n-octane 0.11
    formamide 118.41
    cyclopentanone 12.53
    2-pentanone 2.05
    anisole 1.33
    cyclopentyl methyl ether 2.84
    gamma-butyrolactone 22.86
    1-methoxy-2-propanol 18.99
    pyridine 4.11
    3-pentanone 1.55
    furfural 46.83
    n-dodecane 0.08
    diethylene glycol 29.88
    diisopropyl ether 0.3
    tert-amyl alcohol 3.92
    acetylacetone 4.59
    n-hexadecane 0.09
    acetophenone 2.54
    methyl propionate 3.25
    isopentyl acetate 1.65
    trichloroethylene 2.51
    n-nonanol 1.25
    cyclohexanol 2.71
    benzyl alcohol 3.31
    2-ethylhexanol 1.31
    isooctanol 1.33
    dipropyl ether 1.02
    1,2-dichlorobenzene 0.99
    ethyl lactate 5.21
    propylene carbonate 12.53
    n-methylformamide 77.88
    2-pentanol 1.5
    n-pentane 0.16
    1-propoxy-2-propanol 6.85
    1-methoxy-2-propyl acetate 3.63
    2-(2-methoxypropoxy) propanol 7.91
    mesitylene 0.51
    ε-caprolactone 8.11
    p-cymene 0.57
    epichlorohydrin 9.16
    1,1,1-trichloroethane 0.82
    2-aminoethanol 45.68
    morpholine-4-carbaldehyde 63.62
    sulfolane 48.85
    2,2,4-trimethylpentane 0.13
    2-methyltetrahydrofuran 3.67
    n-hexyl acetate 1.71
    isooctane 0.08
    2-(2-butoxyethoxy)ethanol 8.39
    sec-butyl acetate 0.75
    tert-butyl acetate 1.41
    decalin 0.11
    glycerin 98.41
    diglyme 16.49
    acrylic acid 26.39
    isopropyl myristate 0.67
    n-butyric acid 11.99
    acetyl acetate 2.31
    di(2-ethylhexyl) phthalate 2.5
    ethyl propionate 1.54
    nitromethane 51.09
    1,2-diethoxyethane 1.52
    benzonitrile 2.88
    trioctyl phosphate 1.64
    1-bromopropane 0.53
    gamma-valerolactone 34.39
    n-decanol 0.92
    triethyl phosphate 2.02
    4-methyl-2-pentanol 1.09
    propionitrile 2.58
    vinylene carbonate 15.16
    1,1,2-trichlorotrifluoroethane 33.37
    DMS 2.18
    cumene 0.38
    2-octanol 0.97
    2-hexanone 1.22
    octyl acetate 1.1
    limonene 0.73
    1,2-dimethoxyethane 19.69
    ethyl orthosilicate 1.73
    tributyl phosphate 1.8
    diacetone alcohol 5.78
    N,N-dimethylaniline 1.95
    acrylonitrile 6.63
    aniline 2.2
    1,3-propanediol 30.61
    bromobenzene 0.47
    dibromomethane 0.97
    1,1,2,2-tetrachloroethane 2.35
    2-methyl-cyclohexyl acetate 1.72
    tetrabutyl urea 3.34
    diisobutyl methanol 0.91
    2-phenylethanol 2.56
    styrene 0.34
    dioctyl adipate 1.61
    dimethyl sulfate 17.72
    ethyl butyrate 1.85
    methyl lactate 13.93
    butyl lactate 4.39
    diethyl carbonate 1.51
    propanediol butyl ether 10.69
    triethyl orthoformate 1.98
    p-tert-butyltoluene 0.56
    methyl 4-tert-butylbenzoate 4.6
    morpholine 9.38
    tert-butylamine 1.82
    n-dodecanol 0.69
    dimethoxymethane 15.61
    ethylene carbonate 9.55
    cyrene 15.34
    2-ethoxyethyl acetate 2.23
    2-ethylhexyl acetate 1.25
    1,2,4-trichlorobenzene 1.18
    4-methylpyridine 4.64
    dibutyl ether 0.63
    2,6-dimethyl-4-heptanol 0.91
    DEF 10.73
    dimethyl isosorbide 11.6
    tetrachloroethylene 2.24
    eugenol 7.32
    triacetin 3.16
    span 80 6.92
    1,4-butanediol 14.06
    1,1-dichloroethane 0.78
    2-methyl-1-pentanol 2.0
    methyl formate 58.84
    2-methyl-1-butanol 3.14
    n-decane 0.12
    butyronitrile 2.9
    3,7-dimethyl-1-octanol 1.2
    1-chlorooctane 0.32
    1-chlorotetradecane 0.17
    n-nonane 0.12
    undecane 0.09
    tert-butylcyclohexane 0.12
    cyclooctane 0.1
    cyclopentanol 5.97
    tetrahydropyran 1.87
    tert-amyl methyl ether 1.25
    2,5,8-trioxanonane 13.52
    1-hexene 0.37
    2-isopropoxyethanol 6.02
    2,2,2-trifluoroethanol 37.67
    methyl butyrate 3.17

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction