Hydroxyethyl cetyldimonium phosphate

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  • Identifiers

    CAS number
    85563-48-0

    Molecular formula
    C20H46NO5P

    SMILES
    CCCCCCCCCCCCCCCC[N+](C)(C)CCO.OP(=O)(O)[O-]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 71.4%
    Fatty 49.84%
    Oily 44.6%
    Floral 30.28%
    Fresh 28.76%
    Sweet 28.16%
    Clean 27.77%
    Fruity 26.19%
    Woody 23.45%
    Balsamic 22.46%

     

    Flavor
    Waxy 38.89%
    Mild 34.34%
    Bland 31.74%
    Delicate 23.76%
    Slightly waxy 23.12%
    Faint 22.09%
    Leathery 21.47%
    Oily 21.39%
    Bay oil 21.26%
    Fatty 21.12%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.03 (neutral)

    Molecular weight
    411.6 g/mol

    Flash point

    • 73.76 ˚C est.

  • Synonyms

    • Luviquat mono CP
    • 85563-48-0
    • Hydroxyethyl cetyldimonium phosphate
    • Hexadecyl(2-hydroxyethyl)dimethylammonium dihydrogen phosphate
    • 9G05UO431K
    • EINECS 287-619-1
    • Cetyl dimethyl hydroxyethyl ammonium phosphate
    • BINA QAT 44C
    • 1-Hexadecanaminium, N-(2-hydroxyethyl)-N,N-dimethyl-, phosphate (1:1) (salt)
    • DTXSID5074682
    • 1-Hexadecanaminium, N-(2-hydroxyethyl)-N,N-dimethyl-, phosphate (1:1)
    • CETYL DIMETHYL HYDROXYETHYL AMMONIUM DIHYDROGENPHOSPHATE
    • HEXADECYL(2-HYDROXYETHYL)DIMETHYL AMMONIUM DIHYDROGEN PHOSPHATE
    • RefChem:789468
    • DTXCID9048487
    • HYDROXYETHYL CETYLDIMONIUM PHOSPHATE [INCI]
    • UNII-9G05UO431K
    • HEXADECYL(2-HYDROXYETHYL)DIMETHYLAMMONIU
    • dihydrogen phosphate;hexadecyl-(2-hydroxyethyl)-dimethylazanium
    • SCHEMBL140729
    • orb1985804
    • SGZVXLFVBKDMJH-UHFFFAOYSA-M
    • AKOS027321237
    • Q27272510
    • N-(2-Hydroxyethyl)-N,N-dimethylhexadecan-1-aminium dihydrogen phosphate
    • N-(2-Hydroxyethyl)-N,N-dimethylhexadecan-1-aminium dihydrogenphosphate
    • 85563-48-0

  • Applications

    Hydroxyethyl cetyldimonium phosphate (CAS 85563-48-0) is typically used as a cationic surfactant and conditioning agent in cosmetics and personal care, providing slip, conditioning, and detangling benefits in hair and skin care formulations. It also serves as a surfactant and mild conditioning additive in household cleaning products, helping to emulsify soils and improve the feel of fabrics in laundry formulations. In textile and fabric care applications, it functions as a fabric softener and antistatic additive in detergents and fabric finishes. In coatings and inks, it can act as a surfactant, wetting agent, and stabilizer to improve dispersion and surface quality. In polymer and plastics processing, it acts as a cationic modifier or processing aid and may contribute as an antistatic additive in certain polymer systems. In agricultural formulations, it may be used as an adjuvant to improve spray wetting, adhesion, and dispersion of active ingredients. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 306.29
    methanol 247.52
    isopropanol 377.35
    water 0.18
    ethyl acetate 758.41
    n-propanol 469.53
    acetone 465.31
    n-butanol 595.52
    acetonitrile 159.25
    DMF 450.13
    toluene 258.89
    isobutanol 476.74
    1,4-dioxane 923.44
    methyl acetate 425.55
    THF 1615.85
    2-butanone 585.59
    n-pentanol 335.23
    sec-butanol 497.0
    n-hexane 209.54
    ethylene glycol 22.73
    NMP 826.37
    cyclohexane 1074.5
    DMSO 656.48
    n-butyl acetate 939.9
    n-octanol 299.56
    chloroform 1818.15
    n-propyl acetate 873.36
    acetic acid 364.29
    dichloromethane 1486.21
    cyclohexanone 1763.28
    propylene glycol 71.66
    isopropyl acetate 725.0
    DMAc 630.66
    2-ethoxyethanol 510.29
    isopentanol 613.6
    n-heptane 356.39
    ethyl formate 388.38
    1,2-dichloroethane 1090.2
    n-hexanol 392.41
    2-methoxyethanol 565.14
    isobutyl acetate 609.49
    tetrachloromethane 667.33
    n-pentyl acetate 1022.72
    transcutol 1611.37
    n-heptanol 369.84
    ethylbenzene 200.1
    MIBK 659.12
    2-propoxyethanol 563.09
    tert-butanol 681.3
    MTBE 807.64
    2-butoxyethanol 682.68
    propionic acid 376.66
    o-xylene 264.67
    formic acid 65.78
    diethyl ether 810.31
    m-xylene 227.31
    p-xylene 287.32
    chlorobenzene 381.24
    dimethyl carbonate 134.77
    n-octane 105.31
    formamide 103.15
    cyclopentanone 1230.17
    2-pentanone 748.6
    anisole 291.67
    cyclopentyl methyl ether 1222.12
    gamma-butyrolactone 1155.7
    1-methoxy-2-propanol 587.72
    pyridine 575.34
    3-pentanone 635.15
    furfural 706.7
    n-dodecane 35.32
    diethylene glycol 209.86
    diisopropyl ether 399.68
    tert-amyl alcohol 688.33
    acetylacetone 638.09
    n-hexadecane 43.15
    acetophenone 367.11
    methyl propionate 500.21
    isopentyl acetate 853.14
    trichloroethylene 1533.17
    n-nonanol 294.58
    cyclohexanol 1087.22
    benzyl alcohol 226.94
    2-ethylhexanol 458.93
    isooctanol 424.99
    dipropyl ether 1006.17
    1,2-dichlorobenzene 451.4
    ethyl lactate 298.85
    propylene carbonate 713.38
    n-methylformamide 216.15
    2-pentanol 527.61
    n-pentane 202.21
    1-propoxy-2-propanol 726.84
    1-methoxy-2-propyl acetate 637.81
    2-(2-methoxypropoxy) propanol 345.19
    mesitylene 204.31
    ε-caprolactone 1422.24
    p-cymene 252.51
    epichlorohydrin 1191.47
    1,1,1-trichloroethane 1303.17
    2-aminoethanol 103.96
    morpholine-4-carbaldehyde 793.35
    sulfolane 1541.38
    2,2,4-trimethylpentane 153.56
    2-methyltetrahydrofuran 1439.56
    n-hexyl acetate 808.17
    isooctane 89.26
    2-(2-butoxyethoxy)ethanol 570.04
    sec-butyl acetate 699.38
    tert-butyl acetate 907.21
    decalin 189.44
    glycerin 105.29
    diglyme 1389.51
    acrylic acid 204.12
    isopropyl myristate 285.15
    n-butyric acid 958.61
    acetyl acetate 428.27
    di(2-ethylhexyl) phthalate 179.08
    ethyl propionate 705.74
    nitromethane 527.05
    1,2-diethoxyethane 936.94
    benzonitrile 294.81
    trioctyl phosphate 172.58
    1-bromopropane 864.24
    gamma-valerolactone 1547.51
    n-decanol 183.52
    triethyl phosphate 370.16
    4-methyl-2-pentanol 359.01
    propionitrile 274.96
    vinylene carbonate 532.13
    1,1,2-trichlorotrifluoroethane 971.24
    DMS 332.08
    cumene 171.47
    2-octanol 309.7
    2-hexanone 645.05
    octyl acetate 324.05
    limonene 519.57
    1,2-dimethoxyethane 1098.55
    ethyl orthosilicate 429.74
    tributyl phosphate 226.21
    diacetone alcohol 721.05
    N,N-dimethylaniline 246.46
    acrylonitrile 210.32
    aniline 286.83
    1,3-propanediol 275.84
    bromobenzene 427.35
    dibromomethane 1133.08
    1,1,2,2-tetrachloroethane 1764.8
    2-methyl-cyclohexyl acetate 608.6
    tetrabutyl urea 292.54
    diisobutyl methanol 356.39
    2-phenylethanol 239.98
    styrene 193.06
    dioctyl adipate 368.5
    dimethyl sulfate 276.24
    ethyl butyrate 895.05
    methyl lactate 207.44
    butyl lactate 581.37
    diethyl carbonate 423.42
    propanediol butyl ether 397.27
    triethyl orthoformate 760.53
    p-tert-butyltoluene 238.61
    methyl 4-tert-butylbenzoate 474.72
    morpholine 1233.19
    tert-butylamine 553.99
    n-dodecanol 127.01
    dimethoxymethane 442.67
    ethylene carbonate 603.68
    cyrene 343.77
    2-ethoxyethyl acetate 825.85
    2-ethylhexyl acetate 767.53
    1,2,4-trichlorobenzene 513.2
    4-methylpyridine 517.71
    dibutyl ether 757.04
    2,6-dimethyl-4-heptanol 356.39
    DEF 835.92
    dimethyl isosorbide 665.89
    tetrachloroethylene 1343.61
    eugenol 328.18
    triacetin 657.63
    span 80 401.12
    1,4-butanediol 101.74
    1,1-dichloroethane 991.12
    2-methyl-1-pentanol 369.63
    methyl formate 162.56
    2-methyl-1-butanol 562.73
    n-decane 99.02
    butyronitrile 444.48
    3,7-dimethyl-1-octanol 336.59
    1-chlorooctane 348.24
    1-chlorotetradecane 94.67
    n-nonane 107.83
    undecane 53.87
    tert-butylcyclohexane 155.39
    cyclooctane 248.85
    cyclopentanol 836.73
    tetrahydropyran 1862.06
    tert-amyl methyl ether 696.85
    2,5,8-trioxanonane 632.29
    1-hexene 360.87
    2-isopropoxyethanol 480.66
    2,2,2-trifluoroethanol 186.15
    methyl butyrate 979.95

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction