Hydrofluoric Acid

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  • Identifiers

    CAS number
    7664-39-3

    Molecular formula
    FH

    SMILES
    F

    Safety labels

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Odor impact est.
    Low

    Odor threshold

    • Odor Threshold Low: 0.04 [ppm]. Odor threshold from AIHA
    • Odor ... is detectable in air @ 0.5 to 3 ppm.
    • Odor low 0.0333 mg/cu m; Odor high 0.1333 mg/cu m; Irritating concn 4.17 mg/cu m.

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    0.19 (strong acid)

    Molecular weight
    20.0064 g/mol

    Melting point expt.

    • -92.2 °F for 70% solution (ICSC, 2024)
    • -118.4 °F (EPA, 1998)
    • -83.57 °C
    • -83 °C
    • - 69 °C
    • -118 °F

    Boiling point

    • 152 °F at 760 mmHg for 70% solution (ICSC, 2024)
    • 67.1 °F at 760 mmHg (EPA, 1998)
    • 19.51 °C; 2.5 °C at 400 mm Hg; -13.2 °C at 200 mm Hg; -28.2 °C at 100 mm Hg; -45.0 °C at 40 mm Hg; -56.0 °C at 20 mm Hg; -74.7 °C at 5 mm Hg
    • 20 °C
    • 66,4 °C
    • 67 °F

    Flash point

    • 76.52 ˚C est.
    • Not Flammable (EPA, 1998)

    Solubility expt.

    • Miscible (ICSC, 2024)
    • Miscible (NIOSH, 2024)
    • Miscible with water
    • Very soluble in water
    • Very soluble in alcohol, slightly soluble in ether, soluble in many organic solvents
    • Solubility (wt% at 5 °C): 2.54 (benzene); 1.80 (toluene); 1.28 (m-xylene); 0.27 (tetralin)
    • Solubility in water: very good
    • Solubility in water: miscible
    • Miscible

  • Synonyms

    • HYDROFLUORIC ACID
    • Hydrogen fluoride
    • 7664-39-3
    • Fluorhydric acid
    • Hydrofluoride
    • Rubigine
    • Fluorwasserstoff
    • Antisal 2B
    • Hydrofluoricum acidum
    • Fluorowodor
    • Fluorwaterstof
    • Acido fluoridrico
    • Acide fluorhydrique
    • RCRA waste number U134
    • fluoridohydrogen
    • RGL5YE86CZ
    • DTXSID1049641
    • CHEBI:29228
    • fluoric acid
    • NSC-750679
    • Fluohydric Acid
    • Acid, Fluohydric
    • Acid, Fluorhydric
    • Acid, Hydrofluoric
    • Fluoride, Hydrogen
    • Anhydrous hydrogen fluoride
    • Acidum Fluoricum
    • RefChem:6444
    • Aqueous hydrogen fluoride
    • Hydrofluoric acid, anhydrous
    • DTXCID8029600
    • 231-634-8
    • fluorane
    • Hydrogen-fluoride
    • Hydrogen fluoride, anhydrous
    • MFCD00011346
    • 32057-09-3
    • Fluorowodor [Polish]
    • Caswell No. 484
    • Hydrogenfluorid
    • Fluorwaterstof [Dutch]
    • hydrogenfluoride
    • Hydrogen fluoride (HF)
    • Fluorwasserstoff [German]
    • Hydrofluoric acid, ACS reagent, 48%
    • UN 1052 (anhydrous)
    • Acido fluorhidrico
    • Acido fluoridrico [Italian]
    • Acide fluorhydrique [French]
    • Acido fluorhidrico [Spanish]
    • HSDB 546
    • EINECS 231-634-8
    • UNII-RGL5YE86CZ
    • UN1052
    • RCRA waste no. U134
    • Fluorure d'hydrogene anhydre [French]
    • EPA Pesticide Chemical Code 045601
    • Fluorure d'hydrogene anhydre
    • fluoroorganics
    • fluorum
    • Fluoruro de hidrogeno anhidro [Spanish]
    • Fluoruro de hidrogeno anhidro
    • hyrofluoric acid
    • fluorure d'hydrogene
    • fluoroorganic compound
    • organofluorine compound
    • Hydrofluoric acid 70% by weight or more HF
    • SCHEMBL111
    • fluororganische Verbindungen
    • EC 231-634-8
    • Hydrofluoric acid, 55%, CP
    • HYDROFLUORIC ACID [MI]
    • HYDROGEN FLUORIDE [MI]
    • [HF]
    • CHEMBL1232767
    • HYDROFLUORIC ACID [HSDB]
    • CHEBI:37143
    • HYDROFLUORIC ACID [VANDF]
    • Hydrogen fluoride/Hydrofluoric acid (conc 50% or greater)
    • HYDROFLUORIC ACID [MART.]
    • Hydrofluoric acid, AR, >=40%
    • YCKRFDGAMUMZLT-UHFFFAOYSA-N
    • HYDROFLUORIC ACID [WHO-DD]
    • Hydrofluoric acid, LR, 39-43%
    • Hydrofluoric acid, SAJ first grade
    • HYDROFLUORICUM ACIDUM [HPUS]
    • BDBM50499187
    • Hydrofluoric acid, 48% ACS reagent
    • Hydrofluoric acid, JIS special grade
    • NSC750679
    • AKOS024438092
    • DB11072
    • NSC 750679
    • Hydrofluoric acid, technical, 40-45%
    • 37249-79-9
    • FLUORINE, ISOTOPE OFMASS 18, AT.
    • Hydrofluoric acid, technical grade, 68.0%
    • NS00076201
    • Q2468
    • Hydrofluoric acid, with more than 60% strength
    • Hydrofluoric acid, with not more than 60% strength
    • Hydrogen fluoride, anhydrous [UN1052] [Corrosive]
    • Hydrofluoric acid, for ultratrace analysis, 47-51% (T)
    • Hydrofluoric acid, 48 wt. % in H2O, >=99.99% trace metals basis
    • Hydrofluoric acid, electronic grade,49wt. % in H2O,99.99998%metals basis
    • Hydrofluoric acid, puriss. p.a., reag. ISO, reag. Ph. Eur., >=40%
    • Hydrofluoric acid, semiconductor grade VLSI PURANAL(TM) (Honeywell 17601)
    • Hydrofluoric acid, with more than 60% strength [UN1790] [Corrosive]
    • Hydrofluoric acid, with not more than 60% strength [UN1790] [Corrosive]
    • Hydrofluoric acid, p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 48.0-51.0%
    • Hydrofluoric acid, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=48%
    • Hydrofluoric acid, semiconductor grade MOS PURANAL(TM) (Honeywell 17928), 49.5-50.5%
    • Hydrofluoric acid, semiconductor grade PURANAL(TM) (Honeywell 17735), 40-41%
    • 12381-92-9
    • 7664-39-3

  • Applications

    Hydrofluoric Acid (CAS 7664-39-3) is used in glass processing for etching and frosting, enabling decorative and architectural applications; in electronics, it etches silicon dioxide and removes oxide layers during wafer fabrication; for metal finishing, it serves as a highly effective pickling and surface-cleaning agent to remove oxides from stainless steel and aluminum; in inorganic fluoride production, it is a key reagent for making fluoride compounds such as aluminum fluoride and other fluorides used in metal smelting and specialty chemicals; and as a fluorinating reagent in organic synthesis, it is used to introduce fluoride into certain organic substrates and to prepare fluorinated intermediates.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 105.81
    methanol 219.78
    isopropanol 72.43
    water 269.06
    ethyl acetate 10.91
    n-propanol 63.2
    acetone 41.6
    n-butanol 44.13
    acetonitrile 28.48
    DMF 396.22
    toluene 1.77
    isobutanol 40.69
    1,4-dioxane 41.21
    methyl acetate 20.04
    THF 47.41
    2-butanone 19.91
    n-pentanol 24.01
    sec-butanol 43.2
    n-hexane 1.44
    ethylene glycol 155.45
    NMP 135.05
    cyclohexane 1.46
    DMSO 243.68
    n-butyl acetate 6.88
    n-octanol 11.1
    chloroform 5.6
    n-propyl acetate 7.85
    acetic acid 131.14
    dichloromethane 8.69
    cyclohexanone 19.41
    propylene glycol 99.49
    isopropyl acetate 6.77
    DMAc 184.18
    2-ethoxyethanol 61.15
    isopentanol 30.4
    n-heptane 1.77
    ethyl formate 23.31
    1,2-dichloroethane 8.19
    n-hexanol 15.79
    2-methoxyethanol 141.48
    isobutyl acetate 4.2
    tetrachloromethane 2.12
    n-pentyl acetate 6.8
    transcutol 67.31
    n-heptanol 11.62
    ethylbenzene 1.49
    MIBK 8.54
    2-propoxyethanol 39.23
    tert-butanol 77.48
    MTBE 19.71
    2-butoxyethanol 27.59
    propionic acid 60.28
    o-xylene 3.21
    formic acid 199.82
    diethyl ether 13.58
    m-xylene 2.48
    p-xylene 1.91
    chlorobenzene 2.52
    dimethyl carbonate 16.36
    n-octane 0.78
    formamide 174.9
    cyclopentanone 29.28
    2-pentanone 13.98
    anisole 7.66
    cyclopentyl methyl ether 15.09
    gamma-butyrolactone 43.29
    1-methoxy-2-propanol 82.8
    pyridine 17.44
    3-pentanone 10.18
    furfural 44.6
    n-dodecane 0.74
    diethylene glycol 61.11
    diisopropyl ether 3.97
    tert-amyl alcohol 48.09
    acetylacetone 13.4
    n-hexadecane 0.74
    acetophenone 7.81
    methyl propionate 18.3
    isopentyl acetate 6.02
    trichloroethylene 9.32
    n-nonanol 9.33
    cyclohexanol 22.09
    benzyl alcohol 12.39
    2-ethylhexanol 7.53
    isooctanol 8.61
    dipropyl ether 7.82
    1,2-dichlorobenzene 3.02
    ethyl lactate 12.63
    propylene carbonate 18.04
    n-methylformamide 156.59
    2-pentanol 22.69
    n-pentane 2.39
    1-propoxy-2-propanol 24.9
    1-methoxy-2-propyl acetate 10.57
    2-(2-methoxypropoxy) propanol 24.78
    mesitylene 2.38
    ε-caprolactone 19.85
    p-cymene 2.47
    epichlorohydrin 28.43
    1,1,1-trichloroethane 3.38
    2-aminoethanol 149.85
    morpholine-4-carbaldehyde 116.11
    sulfolane 62.3
    2,2,4-trimethylpentane 1.74
    2-methyltetrahydrofuran 24.15
    n-hexyl acetate 9.35
    isooctane 1.23
    2-(2-butoxyethoxy)ethanol 32.64
    sec-butyl acetate 4.35
    tert-butyl acetate 8.05
    decalin 0.9
    glycerin 136.01
    diglyme 54.92
    acrylic acid 74.56
    isopropyl myristate 4.17
    n-butyric acid 35.9
    acetyl acetate 6.03
    di(2-ethylhexyl) phthalate 7.02
    ethyl propionate 7.58
    nitromethane 107.4
    1,2-diethoxyethane 12.06
    benzonitrile 7.96
    trioctyl phosphate 5.61
    1-bromopropane 4.39
    gamma-valerolactone 51.08
    n-decanol 7.29
    triethyl phosphate 5.24
    4-methyl-2-pentanol 11.94
    propionitrile 20.12
    vinylene carbonate 18.34
    1,1,2-trichlorotrifluoroethane 44.28
    DMS 8.74
    cumene 1.78
    2-octanol 7.19
    2-hexanone 8.56
    octyl acetate 6.29
    limonene 4.07
    1,2-dimethoxyethane 69.33
    ethyl orthosilicate 4.99
    tributyl phosphate 5.63
    diacetone alcohol 23.03
    N,N-dimethylaniline 10.02
    acrylonitrile 32.86
    aniline 10.66
    1,3-propanediol 105.34
    bromobenzene 1.48
    dibromomethane 4.82
    1,1,2,2-tetrachloroethane 9.11
    2-methyl-cyclohexyl acetate 5.43
    tetrabutyl urea 10.28
    diisobutyl methanol 5.3
    2-phenylethanol 8.89
    styrene 1.81
    dioctyl adipate 7.28
    dimethyl sulfate 32.57
    ethyl butyrate 6.38
    methyl lactate 31.65
    butyl lactate 11.12
    diethyl carbonate 4.88
    propanediol butyl ether 32.39
    triethyl orthoformate 6.17
    p-tert-butyltoluene 2.62
    methyl 4-tert-butylbenzoate 14.03
    morpholine 64.04
    tert-butylamine 38.37
    n-dodecanol 5.81
    dimethoxymethane 74.42
    ethylene carbonate 14.43
    cyrene 23.96
    2-ethoxyethyl acetate 9.91
    2-ethylhexyl acetate 4.43
    1,2,4-trichlorobenzene 3.92
    4-methylpyridine 14.77
    dibutyl ether 5.59
    2,6-dimethyl-4-heptanol 5.3
    DEF 43.2
    dimethyl isosorbide 24.23
    tetrachloroethylene 7.61
    eugenol 17.48
    triacetin 10.61
    span 80 20.85
    1,4-butanediol 47.5
    1,1-dichloroethane 5.05
    2-methyl-1-pentanol 17.35
    methyl formate 83.66
    2-methyl-1-butanol 30.01
    n-decane 0.99
    butyronitrile 17.31
    3,7-dimethyl-1-octanol 8.27
    1-chlorooctane 2.78
    1-chlorotetradecane 1.52
    n-nonane 0.97
    undecane 0.83
    tert-butylcyclohexane 1.02
    cyclooctane 0.68
    cyclopentanol 35.11
    tetrahydropyran 19.79
    tert-amyl methyl ether 15.07
    2,5,8-trioxanonane 41.12
    1-hexene 3.48
    2-isopropoxyethanol 30.92
    2,2,2-trifluoroethanol 55.79
    methyl butyrate 12.19

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction