Hydrobenzoin, meso-

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  • Identifiers

    CAS number
    579-43-1

    Molecular formula
    C14H14O2

    SMILES
    C1=CC=C(C=C1)[C@H]([C@H](C2=CC=CC=C2)O)O

    Safety labels

  • Odor profile

    Fragrance
    Sweet 53.49%
    Balsamic 51.83%
    Rose 43.76%
    Fruity 37.38%
    Floral 37.15%
    Bitter 31.84%
    Almond 31.4%
    Honey 31.11%
    Spicy 30.94%
    Green 28.38%

     

    Flavor
    Sweet 63.33%
    Fruity 40.17%
    Bitter 33.47%
    Balsam 33.24%
    Rose 30.61%
    Mild 29.8%
    Floral 28.23%
    Odorless 25.5%
    Honey 24.76%
    Powdery 23.18%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.6

    pKa est.
    7.9 (neutral)

    Molecular weight
    214.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    355°C

    Flash point

    • 176.76 ˚C est.

  • Synonyms

    • meso-Hydrobenzoin
    • 579-43-1
    • meso-1,2-Diphenyl-1,2-ethanediol
    • (1R,2S)-1,2-diphenylethane-1,2-diol
    • meso-Stilbene glycol
    • Hydrobenzoin, meso-
    • meso-1,2-Diphenylethylene glycol
    • CO9A49A84I
    • ERYTHRO-HYDROBENZOIN
    • CHEBI:50015
    • HYDROBENZOIN MESO-FORM [MI]
    • NSC 133570
    • NSC-133570
    • 1,2-ETHANEDIOL, 1,2-DIPHENYL-, (1R,2S)-REL-
    • RefChem:788723
    • HYDROBENZOIN MESO-FORM
    • meso1,2Diphenyl1,2ethanediol
    • rel-(1R,2S)-1,2-Diphenyl-1,2-ethanediol
    • MFCD00064253
    • (R,S)-Dihydrobenzoin
    • rel-(1R,2S)-1,2-Diphenylethane-1,2-diol
    • UNII-CO9A49A84I
    • meso-Hydrobenzoin, 99%
    • SCHEMBL915218
    • DTXSID701021446
    • AC8921
    • AKOS016009876
    • erythro-1,2-Diphenylethane-1,2-diol
    • CS-W000210
    • FH32381
    • AC-23165
    • AS-56888
    • SY106437
    • CS-0132196
    • H0816
    • F240403
    • Q27121702
    • 579-43-1

  • Applications

    Hydrobenzoin, meso- (CAS number: 579-43-1) is primarily used as a synthetic intermediate and a diaryl diol building block in organic chemistry. It is commonly employed as a precursor for preparing aryl diol derivatives and for oxidation to the corresponding diketone (benzil) in exploratory workflows. As an aromatic polyol, it can serve as a feedstock for specialty polymers and resins, including polyesters and polyurethanes, contributing rigidity from the diaryl rings. In coatings, inks and adhesive formulations, it can function as a crosslinkable diol component. In pharmaceutical and medicinal chemistry research, it is often evaluated as a bench-scale intermediate for more complex molecules.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.81
    methanol 6.94
    isopropanol 2.94
    water 0.27
    ethyl acetate 13.49
    n-propanol 4.03
    acetone 16.63
    n-butanol 3.79
    acetonitrile 10.03
    DMF 64.96
    toluene 4.49
    isobutanol 2.79
    1,4-dioxane 43.45
    methyl acetate 15.94
    THF 89.26
    2-butanone 15.18
    n-pentanol 4.72
    sec-butanol 3.05
    n-hexane 1.22
    ethylene glycol 3.44
    NMP 38.83
    cyclohexane 2.36
    DMSO 64.69
    n-butyl acetate 12.37
    n-octanol 7.33
    chloroform 26.41
    n-propyl acetate 12.37
    acetic acid 20.29
    dichloromethane 19.2
    cyclohexanone 32.55
    propylene glycol 3.61
    isopropyl acetate 11.96
    DMAc 80.5
    2-ethoxyethanol 15.75
    isopentanol 5.36
    n-heptane 3.36
    ethyl formate 13.06
    1,2-dichloroethane 24.12
    n-hexanol 9.85
    2-methoxyethanol 22.73
    isobutyl acetate 9.63
    tetrachloromethane 3.07
    n-pentyl acetate 12.68
    transcutol 83.14
    n-heptanol 10.01
    ethylbenzene 7.57
    MIBK 13.96
    2-propoxyethanol 20.68
    tert-butanol 9.08
    MTBE 9.1
    2-butoxyethanol 21.32
    propionic acid 12.06
    o-xylene 6.75
    formic acid 7.7
    diethyl ether 8.79
    m-xylene 5.55
    p-xylene 7.34
    chlorobenzene 9.36
    dimethyl carbonate 16.53
    n-octane 2.06
    formamide 22.2
    cyclopentanone 52.92
    2-pentanone 12.86
    anisole 17.88
    cyclopentyl methyl ether 17.54
    gamma-butyrolactone 66.09
    1-methoxy-2-propanol 17.76
    pyridine 27.15
    3-pentanone 12.14
    furfural 50.28
    n-dodecane 1.54
    diethylene glycol 19.19
    diisopropyl ether 5.05
    tert-amyl alcohol 7.12
    acetylacetone 26.43
    n-hexadecane 1.71
    acetophenone 22.42
    methyl propionate 14.14
    isopentyl acetate 14.35
    trichloroethylene 47.71
    n-nonanol 8.56
    cyclohexanol 5.63
    benzyl alcohol 10.86
    2-ethylhexanol 9.34
    isooctanol 9.59
    dipropyl ether 16.39
    1,2-dichlorobenzene 15.42
    ethyl lactate 11.27
    propylene carbonate 38.04
    n-methylformamide 18.77
    2-pentanol 3.34
    n-pentane 0.8
    1-propoxy-2-propanol 16.23
    1-methoxy-2-propyl acetate 20.48
    2-(2-methoxypropoxy) propanol 25.49
    mesitylene 5.95
    ε-caprolactone 28.17
    p-cymene 8.36
    epichlorohydrin 56.39
    1,1,1-trichloroethane 12.67
    2-aminoethanol 5.48
    morpholine-4-carbaldehyde 45.46
    sulfolane 71.07
    2,2,4-trimethylpentane 1.29
    2-methyltetrahydrofuran 22.86
    n-hexyl acetate 15.95
    isooctane 1.23
    2-(2-butoxyethoxy)ethanol 32.98
    sec-butyl acetate 9.95
    tert-butyl acetate 18.56
    decalin 2.64
    glycerin 10.43
    diglyme 75.14
    acrylic acid 14.34
    isopropyl myristate 9.83
    n-butyric acid 16.26
    acetyl acetate 15.23
    di(2-ethylhexyl) phthalate 9.63
    ethyl propionate 13.02
    nitromethane 45.02
    1,2-diethoxyethane 26.09
    benzonitrile 13.51
    trioctyl phosphate 7.69
    1-bromopropane 6.21
    gamma-valerolactone 58.51
    n-decanol 7.13
    triethyl phosphate 13.74
    4-methyl-2-pentanol 5.57
    propionitrile 9.56
    vinylene carbonate 31.96
    1,1,2-trichlorotrifluoroethane 40.12
    DMS 18.8
    cumene 7.42
    2-octanol 6.12
    2-hexanone 12.66
    octyl acetate 10.61
    limonene 10.16
    1,2-dimethoxyethane 49.53
    ethyl orthosilicate 13.55
    tributyl phosphate 8.49
    diacetone alcohol 22.67
    N,N-dimethylaniline 16.17
    acrylonitrile 16.15
    aniline 7.76
    1,3-propanediol 9.07
    bromobenzene 8.25
    dibromomethane 11.09
    1,1,2,2-tetrachloroethane 42.86
    2-methyl-cyclohexyl acetate 17.56
    tetrabutyl urea 12.77
    diisobutyl methanol 9.46
    2-phenylethanol 14.14
    styrene 6.95
    dioctyl adipate 15.36
    dimethyl sulfate 30.63
    ethyl butyrate 15.96
    methyl lactate 13.84
    butyl lactate 13.21
    diethyl carbonate 14.41
    propanediol butyl ether 15.19
    triethyl orthoformate 16.47
    p-tert-butyltoluene 8.27
    methyl 4-tert-butylbenzoate 27.3
    morpholine 30.84
    tert-butylamine 6.05
    n-dodecanol 6.12
    dimethoxymethane 34.05
    ethylene carbonate 25.43
    cyrene 28.25
    2-ethoxyethyl acetate 19.61
    2-ethylhexyl acetate 11.32
    1,2,4-trichlorobenzene 16.73
    4-methylpyridine 13.54
    dibutyl ether 12.88
    2,6-dimethyl-4-heptanol 9.46
    DEF 21.86
    dimethyl isosorbide 49.29
    tetrachloroethylene 30.46
    eugenol 24.2
    triacetin 23.07
    span 80 19.18
    1,4-butanediol 3.83
    1,1-dichloroethane 9.22
    2-methyl-1-pentanol 6.02
    methyl formate 19.17
    2-methyl-1-butanol 3.89
    n-decane 2.45
    butyronitrile 8.21
    3,7-dimethyl-1-octanol 8.69
    1-chlorooctane 7.16
    1-chlorotetradecane 3.7
    n-nonane 2.13
    undecane 1.87
    tert-butylcyclohexane 2.49
    cyclooctane 1.45
    cyclopentanol 7.34
    tetrahydropyran 23.22
    tert-amyl methyl ether 8.8
    2,5,8-trioxanonane 53.57
    1-hexene 3.68
    2-isopropoxyethanol 12.78
    2,2,2-trifluoroethanol 10.71
    methyl butyrate 17.15

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction