Humulenone

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    19888-05-2

  • Properties

  • Applications

    Humulenone (CAS 19888-05-2) is a hop-derived sesquiterpene ketone formed via oxidation of essential-oil constituents; applications include flavor and fragrance design to impart herbal, woody, spicy, hoppy facets; creation of beer-like aroma for non-alcoholic beverages and flavor replicas; brewing science as a marker of hop aging and oxidation to monitor aroma stability and optimize dry-hopping, storage, and packaging; use as a GC-MS/LC-MS reference standard for profiling and quantifying hop oil oxidation products; natural product and chemical biology research to probe potential bioactivities of sesquiterpene ketones and as a scaffold for screening; education and quality control across the hop supply chain; formulation studies such as encapsulation and antioxidant systems to preserve aroma; with application-specific safety assessment and regulatory compliance required in the target market.

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IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Plectranthus barbatus (Brazil) 2a leaf Plectranthus barbatus Andr. (Coleus barbatus), fam. Lamiaceae (Labiatae) 10.0%
Plectranthus barbatus (Brazil) 2c root Plectranthus barbatus Andr. (Coleus barbatus), fam. Lamiaceae (Labiatae) 0.9%