Hibon

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  • Identifiers

    CAS number
    752-56-7

    Molecular formula
    C33H44N4O10

    SMILES
    CCCC(=O)OC[C@H]([C@H]([C@H](CN1C2=C(C=C(C(=C2)C)C)N=C3C1=NC(=O)NC3=O)OC(=O)CCC)OC(=O)CCC)OC(=O)CCC

    Safety labels

  • Odor profile

    Fragrance
    Fruity 53.01%
    Odorless 39.83%
    Fatty 29.09%
    Grape 27.94%
    Caramellic 24.5%
    Roasted 24.02%
    Buttery 23.8%
    Milky 22.74%
    Winey 22.33%
    Cooked 21.96%

     

    Flavor
    Bitter 73.73%
    Odorless 43.0%
    Bland 35.94%
    Mild 25.62%
    Very mild 23.77%
    Sweet-like 22.22%
    Parsley 19.29%
    Heather 19.15%
    Cedarleaf 19.12%
    Broom 18.88%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    4.1

    pKa est.
    5.78 (weak acid)

    Molecular weight
    656.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    692°C

    Flash point

    • 292.32 ˚C est.

  • Synonyms

    • Riboflavin tetrabutyrate
    • 752-56-7
    • Vitamin B2 tetrabutyrate
    • riboflavin butyrate
    • Hibon
    • Riboflavin 2',3',4',5'-tetrabutyrate
    • F211C9MSGY
    • DTXSID6046892
    • Bituvitan
    • Lacflavin
    • Viras
    • Wakaflavin l
    • DTXCID4026892
    • RefChem:179374
    • (2R,3S,4S)-1,2,4-tris(butanoyloxy)-5-(7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo(g)pteridin-10-yl)pentan-3-yl butanoate
    • (2R,3S,4S)-5-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo(g)pteridin-10(2H)-yl)pentan-1,2,3,4-tetrayl tetrabutanoate
    • 212-034-5
    • Riboflavine tetrabutyrate
    • Riboflavin, 2',3',4',5'-tetrabutanoate
    • Tetra-O-butyrylriboflavin
    • CHEMBL1325863
    • Riboflavine butyrate
    • NCGC00181300-01
    • Vitamin B2 2',3',4',5'-tetrabutyrate
    • Hibon (TN)
    • (2R,3S,4S)-5-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentane-1,2,3,4-tetrayl tetrabutyrate
    • Riboflavin, 2',3',4',5'-tetrabutyrate
    • CCRIS 5849
    • EINECS 212-034-5
    • UNII-F211C9MSGY
    • RIBOFLAVINETETRABUTYRATE
    • Riboflavin tetrabutyrate [JAN]
    • riboflavin-tetrabutyrate
    • Riboflavin butyrate (JP18)
    • MLS004773980
    • orb1706718
    • SCHEMBL22711765
    • SCHEMBL27471800
    • SCHEMBL30113081
    • CHEBI:32097
    • RIBOFLAVIN BUTYRATE [JAN]
    • MJNIWUJSIGSWKK-BBANNHEPSA-N
    • HMS6018J11
    • HY-B2239
    • Tox21_112776
    • BDBM50632830
    • s6441
    • AKOS040742550
    • CS-7761
    • DB14727
    • RIBOFLAVIN TETRABUTYRATE [WHO-DD]
    • [(2R,3S,4S)-2,3,4-tri(butanoyloxy)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)pentyl] butanoate
    • BS-23836
    • CAS-752-56-7
    • SMR001824930
    • SY057397
    • NS00022758
    • R0055
    • D01913
    • D95381
    • SBI-0654055.0001
    • RIBOFLAVIN 2', 3', 4', 5'-TETRABUTYRATE
    • Q27277526
    • RIBOFLAVIN 2', 3', 4', 5'-TETRABUTYRATE [MI]
    • [(2R,3S,4S)-2,3,4-tri(butanoyloxy)-5-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)pentyl] butanoate
    • 2,3,4,5-Tetra-O-butanoyl-1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol
    • 752-56-7

  • Applications

    Hibon (CAS 752-56-7) is commonly used as an intermediate in chemical synthesis and industrial manufacturing; it can serve as a solvent or co-solvent in coatings and inks, as well as in cleaning formulations; it also functions as a processing aid and/or plasticizer in polymer and plastics formulations; it is sometimes used as a formulation component in household products to aid solvent action and dispersion of additives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 44.62
    methanol 59.79
    isopropanol 36.37
    water 6.81
    ethyl acetate 65.93
    n-propanol 44.25
    acetone 131.27
    n-butanol 35.84
    acetonitrile 63.55
    DMF 175.91
    toluene 13.77
    isobutanol 31.22
    1,4-dioxane 64.16
    methyl acetate 107.84
    THF 97.6
    2-butanone 114.38
    n-pentanol 30.07
    sec-butanol 42.03
    n-hexane 1.65
    ethylene glycol 29.47
    NMP 369.54
    cyclohexane 1.83
    DMSO 246.71
    n-butyl acetate 26.27
    n-octanol 7.3
    chloroform 124.85
    n-propyl acetate 33.1
    acetic acid 376.24
    dichloromethane 140.7
    cyclohexanone 137.47
    propylene glycol 35.98
    isopropyl acetate 30.68
    DMAc 375.06
    2-ethoxyethanol 71.95
    isopentanol 24.79
    n-heptane 0.78
    ethyl formate 65.23
    1,2-dichloroethane 87.97
    n-hexanol 14.93
    2-methoxyethanol 107.36
    isobutyl acetate 13.16
    tetrachloromethane 31.33
    n-pentyl acetate 25.86
    transcutol 69.01
    n-heptanol 10.75
    ethylbenzene 6.07
    MIBK 22.15
    2-propoxyethanol 48.98
    tert-butanol 27.22
    MTBE 17.52
    2-butoxyethanol 38.41
    propionic acid 143.07
    o-xylene 10.69
    formic acid 169.25
    diethyl ether 25.61
    m-xylene 6.55
    p-xylene 9.4
    chlorobenzene 26.25
    dimethyl carbonate 69.31
    n-octane 0.53
    formamide 186.83
    cyclopentanone 153.07
    2-pentanone 62.76
    anisole 12.23
    cyclopentyl methyl ether 29.11
    gamma-butyrolactone 224.17
    1-methoxy-2-propanol 65.57
    pyridine 80.16
    3-pentanone 66.42
    furfural 147.37
    n-dodecane 0.4
    diethylene glycol 50.48
    diisopropyl ether 4.48
    tert-amyl alcohol 34.67
    acetylacetone 77.26
    n-hexadecane 0.44
    acetophenone 31.17
    methyl propionate 83.22
    isopentyl acetate 17.62
    trichloroethylene 175.39
    n-nonanol 7.71
    cyclohexanol 37.05
    benzyl alcohol 28.66
    2-ethylhexanol 7.76
    isooctanol 7.41
    dipropyl ether 9.47
    1,2-dichlorobenzene 24.53
    ethyl lactate 29.35
    propylene carbonate 104.77
    n-methylformamide 124.12
    2-pentanol 22.22
    n-pentane 1.97
    1-propoxy-2-propanol 28.46
    1-methoxy-2-propyl acetate 29.2
    2-(2-methoxypropoxy) propanol 30.0
    mesitylene 3.27
    ε-caprolactone 129.02
    p-cymene 3.17
    epichlorohydrin 149.59
    1,1,1-trichloroethane 71.43
    2-aminoethanol 42.15
    morpholine-4-carbaldehyde 177.45
    sulfolane 285.9
    2,2,4-trimethylpentane 0.96
    2-methyltetrahydrofuran 63.65
    n-hexyl acetate 21.6
    isooctane 0.3
    2-(2-butoxyethoxy)ethanol 35.98
    sec-butyl acetate 18.5
    tert-butyl acetate 18.67
    decalin 0.99
    glycerin 67.72
    diglyme 62.35
    acrylic acid 179.84
    isopropyl myristate 6.55
    n-butyric acid 111.71
    acetyl acetate 64.82
    di(2-ethylhexyl) phthalate 14.54
    ethyl propionate 32.49
    nitromethane 358.54
    1,2-diethoxyethane 23.66
    benzonitrile 27.8
    trioctyl phosphate 10.06
    1-bromopropane 36.24
    gamma-valerolactone 223.28
    n-decanol 5.6
    triethyl phosphate 14.83
    4-methyl-2-pentanol 8.66
    propionitrile 44.04
    vinylene carbonate 104.81
    1,1,2-trichlorotrifluoroethane 190.49
    DMS 41.05
    cumene 3.84
    2-octanol 6.76
    2-hexanone 39.76
    octyl acetate 12.51
    limonene 4.77
    1,2-dimethoxyethane 65.91
    ethyl orthosilicate 11.93
    tributyl phosphate 12.91
    diacetone alcohol 39.16
    N,N-dimethylaniline 10.3
    acrylonitrile 68.56
    aniline 34.47
    1,3-propanediol 59.9
    bromobenzene 21.2
    dibromomethane 83.39
    1,1,2,2-tetrachloroethane 129.99
    2-methyl-cyclohexyl acetate 14.98
    tetrabutyl urea 17.61
    diisobutyl methanol 3.12
    2-phenylethanol 17.46
    styrene 7.45
    dioctyl adipate 15.63
    dimethyl sulfate 128.38
    ethyl butyrate 19.02
    methyl lactate 71.67
    butyl lactate 26.81
    diethyl carbonate 17.21
    propanediol butyl ether 27.67
    triethyl orthoformate 14.27
    p-tert-butyltoluene 2.49
    methyl 4-tert-butylbenzoate 24.02
    morpholine 83.63
    tert-butylamine 10.84
    n-dodecanol 4.02
    dimethoxymethane 73.27
    ethylene carbonate 86.7
    cyrene 51.91
    2-ethoxyethyl acetate 46.32
    2-ethylhexyl acetate 14.5
    1,2,4-trichlorobenzene 40.44
    4-methylpyridine 61.82
    dibutyl ether 7.05
    2,6-dimethyl-4-heptanol 3.12
    DEF 90.68
    dimethyl isosorbide 36.14
    tetrachloroethylene 99.52
    eugenol 23.72
    triacetin 39.38
    span 80 25.78
    1,4-butanediol 37.62
    1,1-dichloroethane 71.09
    2-methyl-1-pentanol 24.81
    methyl formate 109.2
    2-methyl-1-butanol 33.63
    n-decane 0.68
    butyronitrile 31.83
    3,7-dimethyl-1-octanol 5.61
    1-chlorooctane 3.7
    1-chlorotetradecane 1.56
    n-nonane 0.58
    undecane 0.51
    tert-butylcyclohexane 0.62
    cyclooctane 0.53
    cyclopentanol 51.73
    tetrahydropyran 44.37
    tert-amyl methyl ether 17.57
    2,5,8-trioxanonane 42.23
    1-hexene 7.07
    2-isopropoxyethanol 39.9
    2,2,2-trifluoroethanol 214.93
    methyl butyrate 42.58

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction