Hexyldecyl myristoyl methylaminopropionate

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  • Identifiers

    CAS number
    645337-39-9

    Molecular formula
    C34H67NO3

    SMILES
    CCCCCCCCCCCCCC(=O)N(C)CCC(=O)OCC(CCCCCC)CCCCCCCC

    Safety labels

  • Odor profile

    Fragrance
    Waxy 56.5%
    Fatty 43.44%
    Oily 42.34%
    Woody 33.82%
    Odorless 30.04%
    Fresh 25.77%
    Herbal 23.73%
    Milky 23.6%
    Savory 22.67%
    Balsamic 22.38%

     

    Flavor
    Bland 38.34%
    Mild 35.89%
    Waxy 33.74%
    Oily 31.25%
    Fatty 30.64%
    Faint 30.55%
    Odorless 25.97%
    Slightly waxy 23.83%
    Fat 22.53%
    Delicate 22.07%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    13.3

    pKa est.
    8.62 (weak base)

    Molecular weight
    537.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    554°C

    Flash point

    • 233.37 ˚C est.

  • Synonyms

    • Amiter MA-HD
    • Hexyldecyl myristoyl methylaminopropionate
    • 1959TW0O9A
    • 645337-39-9
    • AMIEMA MA-HD
    • beta-Alanine, N-methyl-N-(1-oxotetradecyl)-, 2-hexyldecyl ester
    • RefChem:1086684
    • UNII-1959TW0O9A
    • SCHEMBL3899231
    • N-myristoyl-N-methyl-beta-alanine 2-hexyldecyl ester
    • Q27252072
    • (+/-)-HEXYLDECYL MYRISTOYL METHYLAMINOPROPIONATE
    • HEXYLDECYL MYRISTOYL METHYLAMINOPROPIONATE, (+/-)-
    • .BETA.-ALANINE, N-METHYL-N-(1-OXOTETRADECYL)-, 2-HEXYLDECYL ESTER
    • 645337-39-9

  • Applications

    Hexyldecyl myristoyl methylaminopropionate (CAS 645337-39-9) is typically used in cosmetic and personal care formulations as an emollient and conditioning agent, leveraging its long-chain fatty acyl groups to impart slip and a soft skin feel. It can function as a surfactant or co-emulsifier in cleansers and personal care products, helping to stabilize oil-in-water dispersions. In polymer and coating formulations, it may act as a lubricant or processing aid to improve the handling of viscous blends. It may also serve as an intermediate or specialty chemical in the synthesis of other cosmetic actives or detergent components, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 17.13
    methanol 22.55
    isopropanol 17.52
    water 0.35
    ethyl acetate 232.77
    n-propanol 29.8
    acetone 129.45
    n-butanol 31.51
    acetonitrile 53.68
    DMF 203.71
    toluene 110.91
    isobutanol 31.26
    1,4-dioxane 173.95
    methyl acetate 157.19
    THF 421.65
    2-butanone 198.59
    n-pentanol 31.88
    sec-butanol 40.93
    n-hexane 15.32
    ethylene glycol 2.79
    NMP 894.55
    cyclohexane 61.98
    DMSO 195.99
    n-butyl acetate 160.98
    n-octanol 41.56
    chloroform 826.08
    n-propyl acetate 219.36
    acetic acid 113.44
    dichloromethane 860.29
    cyclohexanone 615.8
    propylene glycol 7.92
    isopropyl acetate 199.93
    DMAc 646.26
    2-ethoxyethanol 77.75
    isopentanol 42.01
    n-heptane 11.31
    ethyl formate 100.02
    1,2-dichloroethane 468.22
    n-hexanol 25.07
    2-methoxyethanol 70.51
    isobutyl acetate 134.64
    tetrachloromethane 200.99
    n-pentyl acetate 309.13
    transcutol 429.07
    n-heptanol 40.01
    ethylbenzene 68.58
    MIBK 150.02
    2-propoxyethanol 73.55
    tert-butanol 35.47
    MTBE 99.06
    2-butoxyethanol 127.33
    propionic acid 94.83
    o-xylene 106.51
    formic acid 30.46
    diethyl ether 79.88
    m-xylene 79.24
    p-xylene 104.62
    chlorobenzene 225.11
    dimethyl carbonate 91.68
    n-octane 6.35
    formamide 56.09
    cyclopentanone 598.0
    2-pentanone 183.89
    anisole 131.57
    cyclopentyl methyl ether 263.39
    gamma-butyrolactone 642.99
    1-methoxy-2-propanol 79.08
    pyridine 279.24
    3-pentanone 198.58
    furfural 463.72
    n-dodecane 3.46
    diethylene glycol 28.68
    diisopropyl ether 44.27
    tert-amyl alcohol 71.67
    acetylacetone 312.78
    n-hexadecane 4.26
    acetophenone 222.87
    methyl propionate 191.21
    isopentyl acetate 167.7
    trichloroethylene 947.73
    n-nonanol 45.09
    cyclohexanol 110.42
    benzyl alcohol 77.43
    2-ethylhexanol 37.2
    isooctanol 47.48
    dipropyl ether 78.39
    1,2-dichlorobenzene 320.37
    ethyl lactate 85.95
    propylene carbonate 400.34
    n-methylformamide 85.35
    2-pentanol 32.46
    n-pentane 10.43
    1-propoxy-2-propanol 85.76
    1-methoxy-2-propyl acetate 193.7
    2-(2-methoxypropoxy) propanol 123.45
    mesitylene 56.57
    ε-caprolactone 623.11
    p-cymene 48.82
    epichlorohydrin 583.48
    1,1,1-trichloroethane 613.29
    2-aminoethanol 11.09
    morpholine-4-carbaldehyde 413.11
    sulfolane 1000.05
    2,2,4-trimethylpentane 15.87
    2-methyltetrahydrofuran 357.39
    n-hexyl acetate 250.2
    isooctane 5.73
    2-(2-butoxyethoxy)ethanol 145.91
    sec-butyl acetate 182.28
    tert-butyl acetate 259.69
    decalin 26.36
    glycerin 17.7
    diglyme 417.19
    acrylic acid 78.59
    isopropyl myristate 65.14
    n-butyric acid 188.79
    acetyl acetate 207.66
    di(2-ethylhexyl) phthalate 74.78
    ethyl propionate 211.43
    nitromethane 286.21
    1,2-diethoxyethane 183.63
    benzonitrile 115.44
    trioctyl phosphate 47.34
    1-bromopropane 202.18
    gamma-valerolactone 787.45
    n-decanol 26.35
    triethyl phosphate 128.49
    4-methyl-2-pentanol 27.72
    propionitrile 61.17
    vinylene carbonate 327.01
    1,1,2-trichlorotrifluoroethane 439.78
    DMS 177.23
    cumene 48.45
    2-octanol 38.79
    2-hexanone 172.33
    octyl acetate 89.49
    limonene 82.4
    1,2-dimethoxyethane 206.29
    ethyl orthosilicate 120.22
    tributyl phosphate 70.48
    diacetone alcohol 185.84
    N,N-dimethylaniline 103.74
    acrylonitrile 74.64
    aniline 97.17
    1,3-propanediol 21.94
    bromobenzene 281.98
    dibromomethane 465.42
    1,1,2,2-tetrachloroethane 854.37
    2-methyl-cyclohexyl acetate 175.48
    tetrabutyl urea 105.04
    diisobutyl methanol 28.21
    2-phenylethanol 60.1
    styrene 83.63
    dioctyl adipate 135.56
    dimethyl sulfate 246.65
    ethyl butyrate 196.37
    methyl lactate 84.26
    butyl lactate 182.57
    diethyl carbonate 122.08
    propanediol butyl ether 89.8
    triethyl orthoformate 166.14
    p-tert-butyltoluene 43.14
    methyl 4-tert-butylbenzoate 242.16
    morpholine 227.67
    tert-butylamine 27.25
    n-dodecanol 16.72
    dimethoxymethane 123.61
    ethylene carbonate 279.98
    cyrene 182.7
    2-ethoxyethyl acetate 361.12
    2-ethylhexyl acetate 158.65
    1,2,4-trichlorobenzene 416.26
    4-methylpyridine 272.99
    dibutyl ether 94.28
    2,6-dimethyl-4-heptanol 28.21
    DEF 313.7
    dimethyl isosorbide 315.83
    tetrachloroethylene 583.01
    eugenol 162.58
    triacetin 362.54
    span 80 119.04
    1,4-butanediol 12.48
    1,1-dichloroethane 359.23
    2-methyl-1-pentanol 48.58
    methyl formate 73.0
    2-methyl-1-butanol 50.5
    n-decane 8.76
    butyronitrile 66.84
    3,7-dimethyl-1-octanol 45.27
    1-chlorooctane 53.0
    1-chlorotetradecane 14.01
    n-nonane 8.1
    undecane 5.05
    tert-butylcyclohexane 17.37
    cyclooctane 18.15
    cyclopentanol 100.63
    tetrahydropyran 260.77
    tert-amyl methyl ether 130.49
    2,5,8-trioxanonane 209.37
    1-hexene 39.71
    2-isopropoxyethanol 73.87
    2,2,2-trifluoroethanol 89.75
    methyl butyrate 285.02

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction