Hexanediol disalicylate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    62702-44-7

    Molecular formula
    C20H22O6

    SMILES
    C1=CC=C(C(=C1)C(=O)OCCCCCCOC(=O)C2=CC=CC=C2O)O

    Safety labels

  • Odor profile

    Fragrance
    Floral 73.97%
    Sweet 71.65%
    Balsamic 68.41%
    Herbal 46.6%
    Green 38.7%
    Spicy 34.84%
    Fresh 34.04%
    Fruity 30.45%
    Woody 27.47%
    Rose 25.99%

     

    Flavor
    Bitter 47.82%
    Balsam 34.48%
    Herbal 33.12%
    Floral 31.04%
    Odorless 29.38%
    Wintergreen 26.69%
    Faint 26.26%
    Mild 24.12%
    Ethyl benzoate 23.99%
    Bland 22.73%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.7

    pKa est.
    7.28 (neutral)

    Molecular weight
    358.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    466°C

    Flash point

    • 220.05 ˚C est.

  • Synonyms

    • hexanediol disalicylate
    • 1,6-Hexylene disalicylate
    • ORT515V9E1
    • UNII-ORT515V9E1
    • 1,6-Hexanediol bis(2-hydroxybenzoate)
    • Hexanediol disalicylate [INCI]
    • Benzoic acid, 2-hydroxy-, 1,1'-(1,6-hexanediyl) ester
    • 62702-44-7
    • RefChem:201157
    • SCHEMBL15397549
    • SCHEMBL29408707
    • Q27285805
    • 62702-44-7

  • Applications

    Hexanediol disalicylate (CAS 62702-44-7) is used as a fragrance solvent and fixative in perfumery, helping control volatility and longevity of fragrance ingredients; in cosmetics and personal care it acts as an emollient and solvent for active ingredients and colorants, aiding dispersion and skin feel; in coatings and inks it functions as a plasticizer and processing solvent to improve film flexibility and substrate wetting; in adhesives it serves as a processing aid and plasticizer to adjust tack and bond performance; in polymers and plastics formulations it can act as a processing aid or co-solvent to facilitate resin processing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 26.52
    methanol 30.62
    isopropanol 25.35
    water 0.02
    ethyl acetate 45.04
    n-propanol 29.24
    acetone 214.57
    n-butanol 26.63
    acetonitrile 43.56
    DMF 266.72
    toluene 34.47
    isobutanol 18.69
    1,4-dioxane 106.45
    methyl acetate 64.35
    THF 679.49
    2-butanone 143.93
    n-pentanol 19.17
    sec-butanol 33.11
    n-hexane 1.75
    ethylene glycol 3.82
    NMP 342.81
    cyclohexane 5.51
    DMSO 688.72
    n-butyl acetate 24.93
    n-octanol 7.17
    chloroform 205.12
    n-propyl acetate 26.37
    acetic acid 56.17
    dichloromethane 235.45
    cyclohexanone 212.8
    propylene glycol 10.29
    isopropyl acetate 30.33
    DMAc 433.27
    2-ethoxyethanol 41.52
    isopentanol 21.8
    n-heptane 1.04
    ethyl formate 30.91
    1,2-dichloroethane 212.36
    n-hexanol 13.36
    2-methoxyethanol 90.91
    isobutyl acetate 12.69
    tetrachloromethane 13.5
    n-pentyl acetate 18.95
    transcutol 85.96
    n-heptanol 8.87
    ethylbenzene 12.59
    MIBK 37.49
    2-propoxyethanol 42.44
    tert-butanol 36.39
    MTBE 30.83
    2-butoxyethanol 25.54
    propionic acid 36.3
    o-xylene 18.14
    formic acid 17.0
    diethyl ether 32.38
    m-xylene 13.02
    p-xylene 17.87
    chlorobenzene 47.44
    dimethyl carbonate 34.1
    n-octane 0.79
    formamide 54.64
    cyclopentanone 400.42
    2-pentanone 84.76
    anisole 28.7
    cyclopentyl methyl ether 87.38
    gamma-butyrolactone 295.92
    1-methoxy-2-propanol 64.63
    pyridine 137.29
    3-pentanone 76.93
    furfural 140.47
    n-dodecane 0.81
    diethylene glycol 26.29
    diisopropyl ether 6.59
    tert-amyl alcohol 34.87
    acetylacetone 107.34
    n-hexadecane 0.95
    acetophenone 42.08
    methyl propionate 58.96
    isopentyl acetate 22.24
    trichloroethylene 317.58
    n-nonanol 8.19
    cyclohexanol 49.82
    benzyl alcohol 28.59
    2-ethylhexanol 9.47
    isooctanol 7.97
    dipropyl ether 13.2
    1,2-dichlorobenzene 41.58
    ethyl lactate 19.37
    propylene carbonate 87.4
    n-methylformamide 79.25
    2-pentanol 18.19
    n-pentane 1.63
    1-propoxy-2-propanol 27.98
    1-methoxy-2-propyl acetate 37.72
    2-(2-methoxypropoxy) propanol 31.47
    mesitylene 7.38
    ε-caprolactone 120.31
    p-cymene 6.35
    epichlorohydrin 336.47
    1,1,1-trichloroethane 96.75
    2-aminoethanol 12.27
    morpholine-4-carbaldehyde 147.63
    sulfolane 477.11
    2,2,4-trimethylpentane 1.43
    2-methyltetrahydrofuran 186.54
    n-hexyl acetate 22.15
    isooctane 0.72
    2-(2-butoxyethoxy)ethanol 38.11
    sec-butyl acetate 17.7
    tert-butyl acetate 37.4
    decalin 2.65
    glycerin 18.63
    diglyme 83.91
    acrylic acid 34.61
    isopropyl myristate 9.83
    n-butyric acid 47.96
    acetyl acetate 31.37
    di(2-ethylhexyl) phthalate 13.09
    ethyl propionate 27.32
    nitromethane 150.35
    1,2-diethoxyethane 29.07
    benzonitrile 32.25
    trioctyl phosphate 8.91
    1-bromopropane 65.64
    gamma-valerolactone 270.31
    n-decanol 6.33
    triethyl phosphate 16.92
    4-methyl-2-pentanol 9.6
    propionitrile 37.37
    vinylene carbonate 63.68
    1,1,2-trichlorotrifluoroethane 134.23
    DMS 29.55
    cumene 7.09
    2-octanol 6.1
    2-hexanone 42.17
    octyl acetate 12.91
    limonene 11.28
    1,2-dimethoxyethane 96.77
    ethyl orthosilicate 14.96
    tributyl phosphate 11.68
    diacetone alcohol 58.12
    N,N-dimethylaniline 20.92
    acrylonitrile 53.93
    aniline 43.03
    1,3-propanediol 26.34
    bromobenzene 45.45
    dibromomethane 141.78
    1,1,2,2-tetrachloroethane 266.25
    2-methyl-cyclohexyl acetate 22.23
    tetrabutyl urea 21.12
    diisobutyl methanol 6.72
    2-phenylethanol 21.35
    styrene 17.16
    dioctyl adipate 19.98
    dimethyl sulfate 88.56
    ethyl butyrate 21.63
    methyl lactate 37.46
    butyl lactate 18.78
    diethyl carbonate 15.2
    propanediol butyl ether 19.53
    triethyl orthoformate 19.09
    p-tert-butyltoluene 5.88
    methyl 4-tert-butylbenzoate 32.83
    morpholine 156.49
    tert-butylamine 15.97
    n-dodecanol 4.93
    dimethoxymethane 115.39
    ethylene carbonate 53.29
    cyrene 51.47
    2-ethoxyethyl acetate 29.05
    2-ethylhexyl acetate 17.17
    1,2,4-trichlorobenzene 55.35
    4-methylpyridine 92.13
    dibutyl ether 11.97
    2,6-dimethyl-4-heptanol 6.72
    DEF 96.5
    dimethyl isosorbide 69.8
    tetrachloroethylene 126.46
    eugenol 27.15
    triacetin 30.07
    span 80 24.85
    1,4-butanediol 8.96
    1,1-dichloroethane 118.97
    2-methyl-1-pentanol 18.61
    methyl formate 55.12
    2-methyl-1-butanol 24.63
    n-decane 1.32
    butyronitrile 34.16
    3,7-dimethyl-1-octanol 8.37
    1-chlorooctane 6.48
    1-chlorotetradecane 2.95
    n-nonane 1.1
    undecane 1.01
    tert-butylcyclohexane 1.58
    cyclooctane 1.28
    cyclopentanol 77.44
    tetrahydropyran 145.45
    tert-amyl methyl ether 28.88
    2,5,8-trioxanonane 60.36
    1-hexene 9.79
    2-isopropoxyethanol 26.24
    2,2,2-trifluoroethanol 22.83
    methyl butyrate 41.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction