Hexadecyloctaglycol

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  • Identifiers

    CAS number
    5698-39-5

    Molecular formula
    C32H66O9

    SMILES
    CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO

    Safety labels

  • Odor profile

    Fragrance
    Odorless 34.46%
    Alcoholic 32.98%
    Waxy 31.83%
    Oily 25.79%
    Fresh 24.28%
    Sweet 21.01%
    Clean 19.7%
    Ethereal 18.46%
    Fishy 18.31%
    Fruity 17.71%

     

    Flavor
    Waxy 44.83%
    Fatty 36.35%
    Sweet 34.12%
    Green 33.87%
    Mushroom 33.29%
    Oily 31.65%
    Earthy 29.96%
    Fruity 28.69%
    Floral 27.36%
    Mild 26.18%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.2

    pKa est.
    5.64 (weak acid)

    Molecular weight
    594.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    987°C

    Flash point

    • 257.17 ˚C est.

  • Synonyms

    • 5698-39-5
    • Hexadecyloctaglycol
    • DTXSID70394423
    • RefChem:347495
    • DTXCID20345283
    • Octaethylene glycol monohexadecyl ether
    • 3,6,9,12,15,18,21,24-Octaoxatetracontan-1-ol
    • 2-[2-[2-[2-[2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
    • C16E8
    • SCHEMBL61524
    • orb2939422
    • HY-W250171
    • AS-87460
    • DB-214298
    • CS-0256343
    • NS00076721
    • H55444
    • Octaethylene glycol monohexadecyl ether, BioXtra, >=98.0% (GC)
    • 5698-39-5

  • Applications

    Hexadecyloctaglycol, CAS 5698-39-5, is a long-chain glycol ether used primarily as a nonionic surfactant and solvent. In practice it is employed as an emulsifier and co-solvent in personal care and household cleaning formulations; as a solvent and viscosity modifier in coatings, inks, and adhesives; as a plasticizer or compatibility agent in polymer and coating systems; as an emollient solvent in cosmetic products; and as a cleaning/degreasing solvent in industrial cleaning formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.85
    methanol 1.52
    isopropanol 0.63
    water 0.12
    ethyl acetate 11.84
    n-propanol 1.43
    acetone 6.4
    n-butanol 1.34
    acetonitrile 2.96
    DMF 18.98
    toluene 6.78
    isobutanol 1.28
    1,4-dioxane 14.27
    methyl acetate 9.32
    THF 28.3
    2-butanone 10.28
    n-pentanol 1.57
    sec-butanol 1.66
    n-hexane 0.88
    ethylene glycol 0.48
    NMP 99.27
    cyclohexane 4.15
    DMSO 36.54
    n-butyl acetate 10.42
    n-octanol 3.27
    chloroform 54.77
    n-propyl acetate 11.67
    acetic acid 10.49
    dichloromethane 59.83
    cyclohexanone 36.04
    propylene glycol 0.73
    isopropyl acetate 8.95
    DMAc 53.23
    2-ethoxyethanol 6.83
    isopentanol 1.53
    n-heptane 1.78
    ethyl formate 7.22
    1,2-dichloroethane 28.78
    n-hexanol 1.38
    2-methoxyethanol 5.93
    isobutyl acetate 6.73
    tetrachloromethane 12.61
    n-pentyl acetate 17.51
    transcutol 42.33
    n-heptanol 2.75
    ethylbenzene 4.6
    MIBK 5.93
    2-propoxyethanol 6.32
    tert-butanol 1.23
    MTBE 4.12
    2-butoxyethanol 9.95
    propionic acid 7.22
    o-xylene 7.94
    formic acid 4.6
    diethyl ether 3.81
    m-xylene 5.23
    p-xylene 5.75
    chlorobenzene 11.93
    dimethyl carbonate 8.57
    n-octane 0.96
    formamide 7.65
    cyclopentanone 39.73
    2-pentanone 8.33
    anisole 8.87
    cyclopentyl methyl ether 20.46
    gamma-butyrolactone 50.55
    1-methoxy-2-propanol 5.24
    pyridine 19.41
    3-pentanone 12.35
    furfural 45.36
    n-dodecane 0.56
    diethylene glycol 3.19
    diisopropyl ether 2.21
    tert-amyl alcohol 3.09
    acetylacetone 17.95
    n-hexadecane 0.68
    acetophenone 16.91
    methyl propionate 12.41
    isopentyl acetate 10.03
    trichloroethylene 70.01
    n-nonanol 3.75
    cyclohexanol 5.4
    benzyl alcohol 5.75
    2-ethylhexanol 2.8
    isooctanol 2.97
    dipropyl ether 7.51
    1,2-dichlorobenzene 19.8
    ethyl lactate 8.61
    propylene carbonate 28.39
    n-methylformamide 7.99
    2-pentanol 1.31
    n-pentane 0.6
    1-propoxy-2-propanol 7.59
    1-methoxy-2-propyl acetate 15.75
    2-(2-methoxypropoxy) propanol 14.95
    mesitylene 3.97
    ε-caprolactone 41.47
    p-cymene 4.89
    epichlorohydrin 44.2
    1,1,1-trichloroethane 28.82
    2-aminoethanol 1.13
    morpholine-4-carbaldehyde 42.99
    sulfolane 126.31
    2,2,4-trimethylpentane 1.11
    2-methyltetrahydrofuran 20.87
    n-hexyl acetate 14.6
    isooctane 0.38
    2-(2-butoxyethoxy)ethanol 14.7
    sec-butyl acetate 9.47
    tert-butyl acetate 12.51
    decalin 2.71
    glycerin 2.31
    diglyme 44.2
    acrylic acid 8.28
    isopropyl myristate 5.71
    n-butyric acid 9.91
    acetyl acetate 14.98
    di(2-ethylhexyl) phthalate 6.3
    ethyl propionate 13.39
    nitromethane 26.41
    1,2-diethoxyethane 16.18
    benzonitrile 7.99
    trioctyl phosphate 4.53
    1-bromopropane 10.87
    gamma-valerolactone 57.01
    n-decanol 2.36
    triethyl phosphate 17.46
    4-methyl-2-pentanol 1.14
    propionitrile 3.25
    vinylene carbonate 26.9
    1,1,2-trichlorotrifluoroethane 52.91
    DMS 15.29
    cumene 3.76
    2-octanol 2.51
    2-hexanone 8.5
    octyl acetate 7.28
    limonene 8.36
    1,2-dimethoxyethane 17.17
    ethyl orthosilicate 15.94
    tributyl phosphate 6.59
    diacetone alcohol 10.58
    N,N-dimethylaniline 9.82
    acrylonitrile 4.9
    aniline 6.42
    1,3-propanediol 1.46
    bromobenzene 15.99
    dibromomethane 30.42
    1,1,2,2-tetrachloroethane 68.78
    2-methyl-cyclohexyl acetate 15.91
    tetrabutyl urea 11.28
    diisobutyl methanol 2.26
    2-phenylethanol 4.43
    styrene 4.89
    dioctyl adipate 13.47
    dimethyl sulfate 35.93
    ethyl butyrate 16.2
    methyl lactate 8.04
    butyl lactate 12.72
    diethyl carbonate 11.29
    propanediol butyl ether 6.73
    triethyl orthoformate 19.64
    p-tert-butyltoluene 4.49
    methyl 4-tert-butylbenzoate 22.77
    morpholine 16.33
    tert-butylamine 0.98
    n-dodecanol 1.66
    dimethoxymethane 10.18
    ethylene carbonate 21.39
    cyrene 25.43
    2-ethoxyethyl acetate 24.52
    2-ethylhexyl acetate 11.06
    1,2,4-trichlorobenzene 29.13
    4-methylpyridine 14.66
    dibutyl ether 8.26
    2,6-dimethyl-4-heptanol 2.26
    DEF 20.07
    dimethyl isosorbide 39.92
    tetrachloroethylene 42.26
    eugenol 16.14
    triacetin 34.6
    span 80 11.58
    1,4-butanediol 0.98
    1,1-dichloroethane 15.26
    2-methyl-1-pentanol 2.31
    methyl formate 7.59
    2-methyl-1-butanol 2.07
    n-decane 1.34
    butyronitrile 2.84
    3,7-dimethyl-1-octanol 3.35
    1-chlorooctane 5.53
    1-chlorotetradecane 1.8
    n-nonane 1.22
    undecane 0.81
    tert-butylcyclohexane 1.51
    cyclooctane 2.07
    cyclopentanol 6.0
    tetrahydropyran 14.22
    tert-amyl methyl ether 7.36
    2,5,8-trioxanonane 27.14
    1-hexene 1.9
    2-isopropoxyethanol 5.44
    2,2,2-trifluoroethanol 10.32
    methyl butyrate 16.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction