Hexadecyl ethyleneglycol monoether

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  • Identifiers

    CAS number
    2136-71-2

    Molecular formula
    C18H38O2

    SMILES
    CCCCCCCCCCCCCCCCOCCO

  • Odor profile

    Fragrance
    Waxy 67.91%
    Fatty 54.59%
    Oily 49.04%
    Fruity 36.26%
    Clean 30.16%
    Fresh 28.01%
    Sweet 27.84%
    Odorless 27.82%
    Floral 27.74%
    Citrus 25.62%

     

    Flavor
    Waxy 69.0%
    Fatty 49.73%
    Floral 43.24%
    Soapy 41.09%
    Fat 37.88%
    Mild 37.86%
    Oily 36.81%
    Coconut 34.91%
    Clean 33.72%
    Rose 33.08%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.3

    pKa est.
    6.57 (neutral)

    Molecular weight
    286.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    368°C

    Flash point

    • 169.27 ˚C est.

  • Synonyms

    • 2-(Hexadecyloxy)ethanol
    • 2136-71-2
    • Ethylene glycol monohexadecyl ether
    • 2-Hexadecoxyethanol
    • 2-Hexadecyloxyethanol
    • Hexadecyl ethyleneglycol monoether
    • Ethanol, 2-(hexadecyloxy)-
    • 2-(Hexadecyloxy)ethan-1-ol
    • 69364-63-2
    • Ceteth-1
    • 1-(2-Hydroxyethoxy)hexadecane
    • UO15AM5953
    • UNII-UO15AM5953
    • DTXSID00858846
    • ETHYLENE GLYCOL CETYL ETHER
    • EINECS 218-373-5
    • POLYOXYETHYLENE 20 ISOHEXADECYL ETHER
    • Hexadecylglycol
    • 2-(Hexadecyloxy)ethanol; 1-(2-Hydroxyethoxy)hexadecane; 2-Hexadecoxyethanol; Ethylene Glycol Monohexadecyl Ether
    • 1-O-Hexadecylglycol
    • C16E1;Hexadecylglycol
    • 2-(Hexadecyloxy) ethanol
    • CETETH-1 [INCI]
    • SCHEMBL185805
    • DTXCID00809590
    • C16E1
    • MFCD00043350
    • FP-0099
    • HY-W250466
    • BP-29852
    • FH172143
    • CS-0312254
    • NS00006268
    • E82671
    • Q27291163
    • Ethylene glycol monohexadecyl ether, BioXtra, >=99.0% (TLC)
    • 218-373-5

  • Applications

    Hexadecyl ethyleneglycol monoether (CAS 2136-71-2) is a nonionic surfactant and solvent used as a co-solvent or solvent in coatings and inks, aiding wetting and dispersion of components. It also serves as an emulsifier and solubilizer in cosmetics and personal care formulations, helping solubilize oils and fragrances. In cleaning and household products, it functions as a solvent and wetting agent, improving cleaning efficiency and dispersion of soils. In industrial manufacturing, it can act as a processing aid or additive for polymers and adhesives to improve wetting, mixing, and compatibility. Additionally, it may be used as an intermediate or reagent in the synthesis of other chemicals, depending on formulation needs; use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 51.27
    methanol 43.17
    isopropanol 79.62
    water 0.01
    ethyl acetate 333.26
    n-propanol 84.68
    acetone 169.16
    n-butanol 126.03
    acetonitrile 65.25
    DMF 165.63
    toluene 103.42
    isobutanol 98.24
    1,4-dioxane 355.3
    methyl acetate 158.42
    THF 921.39
    2-butanone 238.16
    n-pentanol 93.36
    sec-butanol 111.71
    n-hexane 75.98
    ethylene glycol 4.59
    NMP 429.96
    cyclohexane 414.96
    DMSO 413.84
    n-butyl acetate 537.38
    n-octanol 122.82
    chloroform 759.94
    n-propyl acetate 463.35
    acetic acid 83.57
    dichloromethane 743.43
    cyclohexanone 829.43
    propylene glycol 15.34
    isopropyl acetate 352.07
    DMAc 280.47
    2-ethoxyethanol 181.65
    isopentanol 176.35
    n-heptane 166.36
    ethyl formate 131.0
    1,2-dichloroethane 579.84
    n-hexanol 121.31
    2-methoxyethanol 179.69
    isobutyl acetate 316.71
    tetrachloromethane 246.5
    n-pentyl acetate 580.21
    transcutol 980.21
    n-heptanol 118.05
    ethylbenzene 104.05
    MIBK 331.08
    2-propoxyethanol 221.04
    tert-butanol 195.07
    MTBE 303.96
    2-butoxyethanol 264.23
    propionic acid 94.75
    o-xylene 116.59
    formic acid 11.38
    diethyl ether 277.79
    m-xylene 100.96
    p-xylene 147.35
    chlorobenzene 188.13
    dimethyl carbonate 53.36
    n-octane 49.78
    formamide 24.25
    cyclopentanone 697.29
    2-pentanone 333.54
    anisole 190.72
    cyclopentyl methyl ether 563.6
    gamma-butyrolactone 605.51
    1-methoxy-2-propanol 209.04
    pyridine 290.33
    3-pentanone 264.14
    furfural 398.88
    n-dodecane 20.69
    diethylene glycol 71.73
    diisopropyl ether 176.52
    tert-amyl alcohol 208.07
    acetylacetone 355.99
    n-hexadecane 26.02
    acetophenone 252.33
    methyl propionate 194.7
    isopentyl acetate 493.94
    trichloroethylene 826.44
    n-nonanol 126.15
    cyclohexanol 315.09
    benzyl alcohol 108.36
    2-ethylhexanol 189.8
    isooctanol 147.1
    dipropyl ether 570.67
    1,2-dichlorobenzene 259.43
    ethyl lactate 137.23
    propylene carbonate 364.65
    n-methylformamide 59.76
    2-pentanol 132.2
    n-pentane 56.02
    1-propoxy-2-propanol 327.97
    1-methoxy-2-propyl acetate 380.08
    2-(2-methoxypropoxy) propanol 208.95
    mesitylene 99.05
    ε-caprolactone 667.43
    p-cymene 143.32
    epichlorohydrin 668.58
    1,1,1-trichloroethane 659.51
    2-aminoethanol 21.75
    morpholine-4-carbaldehyde 382.97
    sulfolane 1033.98
    2,2,4-trimethylpentane 50.81
    2-methyltetrahydrofuran 694.7
    n-hexyl acetate 465.03
    isooctane 33.35
    2-(2-butoxyethoxy)ethanol 307.3
    sec-butyl acetate 374.1
    tert-butyl acetate 502.08
    decalin 100.01
    glycerin 29.38
    diglyme 777.85
    acrylic acid 53.21
    isopropyl myristate 175.7
    n-butyric acid 292.5
    acetyl acetate 208.31
    di(2-ethylhexyl) phthalate 103.75
    ethyl propionate 375.7
    nitromethane 190.5
    1,2-diethoxyethane 584.93
    benzonitrile 166.52
    trioctyl phosphate 97.24
    1-bromopropane 402.51
    gamma-valerolactone 794.53
    n-decanol 82.41
    triethyl phosphate 249.46
    4-methyl-2-pentanol 113.23
    propionitrile 100.3
    vinylene carbonate 245.98
    1,1,2-trichlorotrifluoroethane 430.34
    DMS 186.68
    cumene 93.24
    2-octanol 119.18
    2-hexanone 358.64
    octyl acetate 192.5
    limonene 284.23
    1,2-dimethoxyethane 541.1
    ethyl orthosilicate 268.24
    tributyl phosphate 137.41
    diacetone alcohol 369.99
    N,N-dimethylaniline 152.5
    acrylonitrile 85.37
    aniline 105.89
    1,3-propanediol 62.73
    bromobenzene 234.79
    dibromomethane 550.31
    1,1,2,2-tetrachloroethane 927.95
    2-methyl-cyclohexyl acetate 389.46
    tetrabutyl urea 191.41
    diisobutyl methanol 185.58
    2-phenylethanol 121.59
    styrene 112.57
    dioctyl adipate 257.98
    dimethyl sulfate 135.67
    ethyl butyrate 581.54
    methyl lactate 75.62
    butyl lactate 288.99
    diethyl carbonate 275.27
    propanediol butyl ether 167.95
    triethyl orthoformate 472.81
    p-tert-butyltoluene 133.66
    methyl 4-tert-butylbenzoate 298.26
    morpholine 500.07
    tert-butylamine 159.59
    n-dodecanol 59.93
    dimethoxymethane 178.41
    ethylene carbonate 270.08
    cyrene 216.35
    2-ethoxyethyl acetate 463.87
    2-ethylhexyl acetate 453.25
    1,2,4-trichlorobenzene 294.37
    4-methylpyridine 260.86
    dibutyl ether 457.42
    2,6-dimethyl-4-heptanol 185.58
    DEF 383.17
    dimethyl isosorbide 491.16
    tetrachloroethylene 602.48
    eugenol 202.79
    triacetin 416.2
    span 80 220.4
    1,4-butanediol 25.29
    1,1-dichloroethane 449.38
    2-methyl-1-pentanol 128.16
    methyl formate 47.33
    2-methyl-1-butanol 146.88
    n-decane 53.77
    butyronitrile 158.23
    3,7-dimethyl-1-octanol 167.97
    1-chlorooctane 196.76
    1-chlorotetradecane 58.59
    n-nonane 58.16
    undecane 30.58
    tert-butylcyclohexane 74.61
    cyclooctane 107.66
    cyclopentanol 265.97
    tetrahydropyran 766.74
    tert-amyl methyl ether 282.36
    2,5,8-trioxanonane 410.94
    1-hexene 138.04
    2-isopropoxyethanol 181.88
    2,2,2-trifluoroethanol 40.86
    methyl butyrate 501.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction