Heroin

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  • Identifiers

    CAS number
    561-27-3

    Molecular formula
    C21H23NO5

    SMILES
    CC(=O)O[C@H]1C=C[C@H]2[C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)OC(=O)C)CCN3C

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 65.89%
    Fresh 17.88%
    Nutty 17.2%
    Floral 16.41%
    Animal 15.82%
    Milky 15.58%
    Clean 15.41%
    Vanilla 15.3%
    Cooling 14.89%
    Cooked 14.75%

     

    Flavor
    Bitter 90.17%
    Odorless 25.81%
    Bland 24.28%
    Sweet-like 21.61%
    Cedarleaf 20.01%
    Parsley 18.83%
    Lovage 18.56%
    Ripe apricot 18.52%
    Nitrile 18.39%
    Heather 18.34%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.5

    pKa est.
    6.37 (neutral)

    Molecular weight
    369.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 173 °C

    Boiling point

    • 272-274 °C at 1.20E+01 mm Hg
    • BP: 272-274 °C at 12 mm Hg

    Flash point

    • 207.4 ˚C est.

    Solubility expt.

    • 600 mg/L (at 25 °C)
    • In water, 60 mg/L at 25 °C
    • 1 g dissolves in 1,700 mL water
    • 1 g dissolves in: 1.5 mL chloroform; 31 mL alcohol; 100 mL ether
    • Soluble in alkalies; slightly soluble in ammonia or sodium carbonate solution
    • Very soluble in benzene

  • Synonyms

    • HEROIN
    • Diacetylmorphine
    • Diamorphine
    • Acetomorphine
    • 3,6-Diacetylmorphine
    • Diaphorm
    • Eclorion
    • Morphacetin
    • Preza
    • O,O'-Diacetylmorphine
    • Morphine diacetate
    • 561-27-3
    • Acetomorfine
    • Diacetylmorfin
    • Diamorfina
    • Diasetilmorfin
    • Diacephin
    • Heroien
    • Heroiin
    • Herolan
    • Persian
    • Aspron
    • Dooje
    • Dujie
    • Eroina
    • Iroini
    • Stuff
    • Diasetielmorfien
    • Diasetylmorfiimi
    • Diazetylmorphine
    • Amsterdam Marble
    • Diacetyl morphine
    • TNT (narcotic)
    • 3,6-O-Diacetylmorphine
    • Junk
    • Scot
    • HSDB 6473
    • Boy [Street Name]
    • Crap [Street Name]
    • Scag [Street Name]
    • Hairy [Street Name]
    • Harry [Street Name]
    • Horse [Street Name]
    • Noise [Street Name]
    • Rufus [Street Name]
    • Smack [Street Name]
    • 7,8-Dihydro-4,5-alpha-epoxy-17-methylmorphinan-3,6-alpha-diol diacetate
    • Joy powder [Street Name]
    • White stuff [Street Name]
    • Indian Pink [Street Name]
    • Penang Pink [Street Name]
    • EINECS 209-217-7
    • Persian brown [Street Name]
    • Mexican Brown [Street Name]
    • Hairy
    • Harry
    • Diamorphine (BAN)
    • Malaysian Pink [Street Name]
    • White stuff
    • IDS-NH-001
    • DTXSID6046761
    • UNII-70D95007SX
    • CHEBI:27808
    • DIAMORPHINE-
    • IDS-NH-001(SECT.3)
    • Diamorphine (TN)
    • HEROIN [HSDB]
    • 70D95007SX
    • J6.494G
    • JOY POWDER
    • Acetomorphin
    • 7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (ester)
    • DIACETYLMORPHINE [MI]
    • DIAMORPHINE [WHO-DD]
    • (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (ester)
    • DTXCID4026761
    • Smack
    • Boy (Street Name)
    • Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, diacetate (ester)
    • Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, (5alpha,6alpha)-, diacetate (ester)
    • Crap (Street Name)
    • Scag (Street Name)
    • Hairy (Street Name)
    • Harry (Street Name)
    • Horse (Street Name)
    • Noise (Street Name)
    • Rufus (Street Name)
    • Smack (Street Name)
    • Rufus
    • Crap
    • Persian brown
    • Malaysian Pink
    • Mexican Brown
    • White junk
    • Black tar
    • Heroin (Diacetylmorphine)
    • Black tar (Street Name)
    • Black tar [Street Name]
    • Indian Pink
    • Penang Pink
    • 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diyl diacetate
    • Joy powder (Street Name)
    • White junk (Street Name)
    • White junk [Street Name]
    • White stuff (Street Name)
    • Indian Pink (Street Name)
    • Penang Pink (Street Name)
    • Mexican Brown (Street Name)
    • Persian brown (Street Name)
    • [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl] acetate
    • Malaysian Pink (Street Name)
    • Heroin (3,6-Diacetylmorphine)
    • Scag
    • Heroin (1.0 mg/mL in Acetonitrile)
    • (5.alpha.,6.alpha.)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (ester)
    • [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate
    • BOY
    • Black tar [Street Name]
    • White junk [Street Name]
    • Diamorphone
    • Diacetylmorphone
    • DEA No. 9200
    • ((4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro(3,2-e)isoquinolin-7-yl) acetate
    • ((4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro(3,2-e)isoquinoline-7-yl) acetate
    • (1S,5R,13R,14S,17R)-14-(acetyloxy)-4-methyl-12-oxa-4-azapentacyclo(9.6.1.01,13.05,17.07,18)octadeca-7(18),8,10,15-tetraen-10-yl acetate
    • (1S,5R,13R,14S,17R)-14-(acetyloxy)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-10-yl acetate
    • 3-6 Diacetylmorphine
    • Diacetylmorphine (Heroin)

  • Applications

    Heroin (diacetylmorphine) has no widely recognized industrial or consumer applications; legitimate use is limited to tightly regulated medical contexts, such as analgesia for severe pain or in specialized opioid addiction treatment programs under strict supervision, with any other use subject to prohibition and stringent regulation.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.0
    methanol 12.29
    isopropanol 5.07
    water 0.72
    ethyl acetate 31.21
    n-propanol 6.63
    acetone 39.56
    n-butanol 6.92
    acetonitrile 23.24
    DMF 79.39
    toluene 5.44
    isobutanol 5.86
    1,4-dioxane 35.81
    methyl acetate 32.43
    THF 34.97
    2-butanone 28.44
    n-pentanol 6.1
    sec-butanol 3.23
    n-hexane 0.15
    ethylene glycol 10.43
    NMP 97.09
    cyclohexane 0.45
    DMSO 81.46
    n-butyl acetate 21.44
    n-octanol 3.05
    chloroform 116.38
    n-propyl acetate 22.19
    acetic acid 116.89
    dichloromethane 100.0
    cyclohexanone 54.74
    propylene glycol 3.5
    isopropyl acetate 18.68
    DMAc 135.06
    2-ethoxyethanol 31.93
    isopentanol 8.35
    n-heptane 0.15
    ethyl formate 29.97
    1,2-dichloroethane 47.06
    n-hexanol 5.37
    2-methoxyethanol 49.54
    isobutyl acetate 17.49
    tetrachloromethane 9.88
    n-pentyl acetate 15.64
    transcutol 61.87
    n-heptanol 4.79
    ethylbenzene 3.04
    MIBK 15.1
    2-propoxyethanol 46.92
    tert-butanol 5.47
    MTBE 2.73
    2-butoxyethanol 28.7
    propionic acid 25.4
    o-xylene 4.06
    formic acid 83.94
    diethyl ether 5.69
    m-xylene 4.67
    p-xylene 5.13
    chlorobenzene 15.73
    dimethyl carbonate 38.89
    n-octane 0.11
    formamide 92.46
    cyclopentanone 56.83
    2-pentanone 21.79
    anisole 8.92
    cyclopentyl methyl ether 11.25
    gamma-butyrolactone 92.53
    1-methoxy-2-propanol 29.83
    pyridine 37.7
    3-pentanone 20.24
    furfural 86.73
    n-dodecane 0.19
    diethylene glycol 58.31
    diisopropyl ether 1.8
    tert-amyl alcohol 3.71
    acetylacetone 41.98
    n-hexadecane 0.23
    acetophenone 21.61
    methyl propionate 33.12
    isopentyl acetate 20.86
    trichloroethylene 137.76
    n-nonanol 3.87
    cyclohexanol 8.29
    benzyl alcohol 17.81
    2-ethylhexanol 4.51
    isooctanol 4.78
    dipropyl ether 3.85
    1,2-dichlorobenzene 19.37
    ethyl lactate 20.77
    propylene carbonate 50.91
    n-methylformamide 48.9
    2-pentanol 3.23
    n-pentane 0.15
    1-propoxy-2-propanol 22.98
    1-methoxy-2-propyl acetate 34.04
    2-(2-methoxypropoxy) propanol 28.02
    mesitylene 2.78
    ε-caprolactone 52.8
    p-cymene 3.28
    epichlorohydrin 83.6
    1,1,1-trichloroethane 34.08
    2-aminoethanol 10.26
    morpholine-4-carbaldehyde 110.46
    sulfolane 87.6
    2,2,4-trimethylpentane 0.14
    2-methyltetrahydrofuran 15.0
    n-hexyl acetate 14.21
    isooctane 0.12
    2-(2-butoxyethoxy)ethanol 32.13
    sec-butyl acetate 13.96
    tert-butyl acetate 14.91
    decalin 0.39
    glycerin 21.26
    diglyme 58.56
    acrylic acid 38.79
    isopropyl myristate 6.8
    n-butyric acid 38.8
    acetyl acetate 41.52
    di(2-ethylhexyl) phthalate 14.59
    ethyl propionate 19.83
    nitromethane 174.86
    1,2-diethoxyethane 14.88
    benzonitrile 24.69
    trioctyl phosphate 9.35
    1-bromopropane 10.15
    gamma-valerolactone 118.67
    n-decanol 3.0
    triethyl phosphate 14.88
    4-methyl-2-pentanol 3.83
    propionitrile 18.37
    vinylene carbonate 71.27
    1,1,2-trichlorotrifluoroethane 98.98
    DMS 27.92
    cumene 2.56
    2-octanol 2.54
    2-hexanone 16.08
    octyl acetate 9.43
    limonene 3.34
    1,2-dimethoxyethane 41.76
    ethyl orthosilicate 12.43
    tributyl phosphate 11.91
    diacetone alcohol 23.29
    N,N-dimethylaniline 7.01
    acrylonitrile 34.58
    aniline 13.36
    1,3-propanediol 19.69
    bromobenzene 14.37
    dibromomethane 44.39
    1,1,2,2-tetrachloroethane 80.02
    2-methyl-cyclohexyl acetate 17.98
    tetrabutyl urea 16.35
    diisobutyl methanol 2.97
    2-phenylethanol 20.24
    styrene 3.63
    dioctyl adipate 14.47
    dimethyl sulfate 62.55
    ethyl butyrate 16.07
    methyl lactate 29.8
    butyl lactate 19.14
    diethyl carbonate 15.89
    propanediol butyl ether 17.48
    triethyl orthoformate 14.06
    p-tert-butyltoluene 2.63
    methyl 4-tert-butylbenzoate 22.33
    morpholine 34.98
    tert-butylamine 1.84
    n-dodecanol 2.37
    dimethoxymethane 47.72
    ethylene carbonate 58.29
    cyrene 40.03
    2-ethoxyethyl acetate 29.68
    2-ethylhexyl acetate 15.89
    1,2,4-trichlorobenzene 27.56
    4-methylpyridine 30.34
    dibutyl ether 3.36
    2,6-dimethyl-4-heptanol 2.97
    DEF 33.84
    dimethyl isosorbide 43.26
    tetrachloroethylene 56.59
    eugenol 27.84
    triacetin 26.59
    span 80 19.68
    1,4-butanediol 10.04
    1,1-dichloroethane 32.91
    2-methyl-1-pentanol 7.1
    methyl formate 49.17
    2-methyl-1-butanol 6.09
    n-decane 0.26
    butyronitrile 14.6
    3,7-dimethyl-1-octanol 4.34
    1-chlorooctane 1.57
    1-chlorotetradecane 0.94
    n-nonane 0.18
    undecane 0.22
    tert-butylcyclohexane 0.25
    cyclooctane 0.18
    cyclopentanol 9.15
    tetrahydropyran 14.8
    tert-amyl methyl ether 2.88
    2,5,8-trioxanonane 44.68
    1-hexene 0.87
    2-isopropoxyethanol 22.58
    2,2,2-trifluoroethanol 66.77
    methyl butyrate 25.58

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction