Henicosan-11-ol

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  • Identifiers

    CAS number
    3381-26-8

    Molecular formula
    C21H44O

    SMILES
    CCCCCCCCCCC(CCCCCCCCCC)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Waxy 64.75%
    Fatty 62.24%
    Oily 61.45%
    Fruity 48.35%
    Floral 39.87%
    Citrus 30.13%
    Fresh 29.26%
    Clean 26.94%
    Coconut 24.63%
    Soapy 24.35%

     

    Flavor
    Waxy 50.05%
    Fatty 34.69%
    Mild 33.26%
    Fat 29.68%
    Bland 27.86%
    Alkane 27.55%
    Flower 25.33%
    Slightly waxy 24.7%
    Delicate 24.41%
    Oily 24.2%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.7

    pKa est.
    7.38 (neutral)

    Molecular weight
    312.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    385°C

    Flash point

    • 169.37 ˚C est.

  • Synonyms

    • 11-Heneicosanol
    • Henicosan-11-ol
    • 3381-26-8
    • EINECS 222-184-3
    • DTXSID90187470
    • NSC 158433
    • RefChem:783523
    • DTXCID00109961
    • 222-184-3
    • 11-Henicosanol
    • MFCD00026547
    • Di-n-decyl carbinol
    • heneicosan-11-ol
    • 11-Henicosanol #
    • 11-hydroxyhenicosane
    • NSC158433
    • 11-hydroxyheneicosane
    • SCHEMBL631940
    • CHEBI:197501
    • STL386381
    • AKOS025250458
    • FH35769
    • HY-W282663
    • NSC-158433
    • AS-86810
    • SY337802
    • DB-048497
    • CS-0327724
    • NS00029549
    • F71783
    • F727164
    • 3381-26-8

  • Applications

    Henicosan-11-ol (CAS 3381-26-8) is a long-chain fatty secondary alcohol commonly used as an intermediate and additive in various industrial processes. Practical applications include: serving as a fragrance component in perfumery with potential to act as a scent fixative; acting as an emollient and conditioning ingredient in cosmetics and personal care products; used as a lubricant or processing aid in polymer and plastics processing; incorporated as an additive in coatings, inks, and adhesives to improve workability and lubrication properties; and may function as a solvent or co-solvent in cleaning and industrial formulations, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 107.66
    methanol 58.1
    isopropanol 202.33
    water 0.01
    ethyl acetate 921.17
    n-propanol 182.74
    acetone 482.62
    n-butanol 304.1
    acetonitrile 108.2
    DMF 470.68
    toluene 301.98
    isobutanol 226.7
    1,4-dioxane 786.34
    methyl acetate 408.47
    THF 2374.11
    2-butanone 653.56
    n-pentanol 189.27
    sec-butanol 282.89
    n-hexane 279.16
    ethylene glycol 3.87
    NMP 1119.01
    cyclohexane 1244.98
    DMSO 655.55
    n-butyl acetate 1601.66
    n-octanol 301.43
    chloroform 1434.66
    n-propyl acetate 1153.91
    acetic acid 120.07
    dichloromethane 1384.18
    cyclohexanone 2083.6
    propylene glycol 19.48
    isopropyl acetate 1062.69
    DMAc 790.41
    2-ethoxyethanol 277.43
    isopentanol 431.98
    n-heptane 546.81
    ethyl formate 275.8
    1,2-dichloroethane 1135.82
    n-hexanol 294.34
    2-methoxyethanol 302.45
    isobutyl acetate 866.41
    tetrachloromethane 536.45
    n-pentyl acetate 1555.75
    transcutol 1917.9
    n-heptanol 300.43
    ethylbenzene 264.14
    MIBK 939.76
    2-propoxyethanol 462.92
    tert-butanol 486.79
    MTBE 979.55
    2-butoxyethanol 566.37
    propionic acid 182.14
    o-xylene 307.31
    formic acid 10.77
    diethyl ether 816.98
    m-xylene 271.46
    p-xylene 395.65
    chlorobenzene 495.38
    dimethyl carbonate 136.59
    n-octane 160.85
    formamide 26.73
    cyclopentanone 1779.98
    2-pentanone 916.91
    anisole 466.68
    cyclopentyl methyl ether 1585.81
    gamma-butyrolactone 1433.86
    1-methoxy-2-propanol 416.89
    pyridine 689.65
    3-pentanone 753.2
    furfural 736.52
    n-dodecane 57.79
    diethylene glycol 108.99
    diisopropyl ether 580.97
    tert-amyl alcohol 518.91
    acetylacetone 929.63
    n-hexadecane 74.46
    acetophenone 567.0
    methyl propionate 546.69
    isopentyl acetate 1593.77
    trichloroethylene 1639.1
    n-nonanol 325.28
    cyclohexanol 723.67
    benzyl alcohol 203.49
    2-ethylhexanol 491.19
    isooctanol 376.97
    dipropyl ether 1722.04
    1,2-dichlorobenzene 622.68
    ethyl lactate 274.05
    propylene carbonate 892.64
    n-methylformamide 118.37
    2-pentanol 350.9
    n-pentane 185.02
    1-propoxy-2-propanol 774.16
    1-methoxy-2-propyl acetate 1094.54
    2-(2-methoxypropoxy) propanol 463.03
    mesitylene 261.07
    ε-caprolactone 1647.97
    p-cymene 370.26
    epichlorohydrin 1391.86
    1,1,1-trichloroethane 1585.44
    2-aminoethanol 25.48
    morpholine-4-carbaldehyde 844.27
    sulfolane 2170.76
    2,2,4-trimethylpentane 153.07
    2-methyltetrahydrofuran 1778.91
    n-hexyl acetate 1268.82
    isooctane 113.07
    2-(2-butoxyethoxy)ethanol 654.74
    sec-butyl acetate 1045.08
    tert-butyl acetate 1485.74
    decalin 284.89
    glycerin 33.59
    diglyme 1674.7
    acrylic acid 88.82
    isopropyl myristate 539.6
    n-butyric acid 668.98
    acetyl acetate 518.19
    di(2-ethylhexyl) phthalate 252.52
    ethyl propionate 979.1
    nitromethane 312.09
    1,2-diethoxyethane 1512.53
    benzonitrile 321.95
    trioctyl phosphate 248.9
    1-bromopropane 940.5
    gamma-valerolactone 1774.64
    n-decanol 211.44
    triethyl phosphate 621.86
    4-methyl-2-pentanol 312.72
    propionitrile 209.98
    vinylene carbonate 525.22
    1,1,2-trichlorotrifluoroethane 745.63
    DMS 484.96
    cumene 229.9
    2-octanol 320.6
    2-hexanone 887.42
    octyl acetate 555.37
    limonene 797.21
    1,2-dimethoxyethane 1082.59
    ethyl orthosilicate 680.77
    tributyl phosphate 354.55
    diacetone alcohol 910.44
    N,N-dimethylaniline 385.76
    acrylonitrile 155.17
    aniline 261.91
    1,3-propanediol 97.23
    bromobenzene 638.72
    dibromomethane 1045.66
    1,1,2,2-tetrachloroethane 1801.07
    2-methyl-cyclohexyl acetate 1040.04
    tetrabutyl urea 507.6
    diisobutyl methanol 500.99
    2-phenylethanol 258.97
    styrene 288.34
    dioctyl adipate 675.27
    dimethyl sulfate 317.76
    ethyl butyrate 1624.29
    methyl lactate 165.38
    butyl lactate 709.05
    diethyl carbonate 739.82
    propanediol butyl ether 324.03
    triethyl orthoformate 1294.3
    p-tert-butyltoluene 363.57
    methyl 4-tert-butylbenzoate 715.64
    morpholine 1065.82
    tert-butylamine 414.76
    n-dodecanol 154.19
    dimethoxymethane 485.21
    ethylene carbonate 633.01
    cyrene 397.65
    2-ethoxyethyl acetate 1158.12
    2-ethylhexyl acetate 1414.53
    1,2,4-trichlorobenzene 689.22
    4-methylpyridine 703.83
    dibutyl ether 1388.23
    2,6-dimethyl-4-heptanol 500.99
    DEF 1066.45
    dimethyl isosorbide 1123.78
    tetrachloroethylene 1128.97
    eugenol 427.39
    triacetin 974.2
    span 80 491.53
    1,4-butanediol 33.91
    1,1-dichloroethane 1022.56
    2-methyl-1-pentanol 285.65
    methyl formate 89.77
    2-methyl-1-butanol 339.69
    n-decane 157.32
    butyronitrile 381.89
    3,7-dimethyl-1-octanol 456.04
    1-chlorooctane 532.63
    1-chlorotetradecane 164.21
    n-nonane 169.09
    undecane 87.52
    tert-butylcyclohexane 225.56
    cyclooctane 328.94
    cyclopentanol 591.86
    tetrahydropyran 1904.18
    tert-amyl methyl ether 872.07
    2,5,8-trioxanonane 845.07
    1-hexene 441.28
    2-isopropoxyethanol 324.64
    2,2,2-trifluoroethanol 58.83
    methyl butyrate 1282.5

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction