Helium

Overview IFRA Request a quote

  • Identifiers

    CAS number
    7440-59-7

    Molecular formula
    He

    SMILES
    [He]

    Safety labels

    Compressed Gas
    Compressed Gas

  • Odor profile

  • Properties

    pKa est.
    9.87 (weak base)

    Molecular weight
    4.0026 g/mol

    Melting point expt.

    • -272.2
    • No triple point
    • -272.2 °C

    Boiling point

    • -269
    • -268.928 °C
    • -268.9 °C

    Flash point

    • -88.3 ˚C est.

    Solubility expt.

    • 1.5mg/L
    • Very slightly soluble in water: at 0 °C, 0.97 mL/100 mL; at 50 °C, 1.08 mL/100 mL
    • Insoluble in ethanol
    • In water, 2.50 mg/L at 21 °C
    • 2.5 mg/L @ 21C (exp)
    • Solubility in water, ml/100ml at 20 °C: 0.86

  • Synonyms

    • HELIUM
    • Atomic helium
    • Helium-4
    • 7440-59-7
    • p-Helium
    • O-Helium
    • Helium (USP)
    • Helium 4
    • Helium [USP]
    • INS NO.939
    • E939
    • INS-939
    • 206GF3GB41
    • E-939
    • He
    • DTXSID7036402
    • CHEBI:30217
    • CHEBI:33681
    • 71086-78-7
    • CHEBI:30218
    • CHEBI:30219
    • RefChem:5878
    • HELIUM, USP
    • DTXCID5016402
    • CHEBI:30220
    • CHEBI:33315
    • 231-168-5
    • 275-187-7
    • helio
    • helium atom
    • [He]
    • helium(0)
    • EINECS 275-187-7
    • HSDB 553
    • EINECS 231-168-5
    • UN1046
    • UN1963
    • Helium element
    • UNII-206GF3GB41
    • Element Helium
    • Element:Helium
    • Element-He
    • Element:He
    • Helium (atomic)
    • Helium (element)
    • He (element)
    • Helium, compressed
    • Hydridohelium(1+) ion
    • HELIUM [VANDF]
    • HELIUM [HSDB]
    • HELIUM [FCC]
    • HELIUM [WHO-DD]
    • HELIUM [MI]
    • HELIUM [MART.]
    • HELIUM [GREEN BOOK]
    • Helium, compressed [UN1046] [Nonflammable gas]
    • SCHEMBL16770
    • HELIUM [EP MONOGRAPH]
    • HELIUM [USP MONOGRAPH]
    • Helium, >=99.995%
    • Helium, >=99.999%
    • CHEMBL1796997
    • SWQJXJOGLNCZEY-UHFFFAOYSA-N
    • DTXSID801018818
    • DB09155
    • Helium, Messer(R) CANGas, 99.999%
    • Q560
    • E 939
    • NS00076386
    • D04420
    • Helium, refrigerated liquid (cryogenic liquid)
    • Helium, compressed [UN1046] [Nonflammable gas]
    • Helium, refrigerated liquid (cryogenic liquid) [UN1963] [Nonflammable gas]
    • 7440-59-7

  • Applications

    Helium (CAS 7440-59-7) is widely used as a cryogenic cooling medium and an inert purge gas across industries, notably cooling superconducting magnets in MRI and NMR systems; enabling helium leak testing and inert purging in electronics, vacuum systems, and manufacturing lines; serving as a shielding gas for welding and metal fabrication (often in mixtures with other gases); acting as a carrier gas for gas chromatography and as a purge/blanketing gas in electronics and fiber-optic fabrication; and used to inflate balloons and other light-air applications. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 14.29
    methanol 18.82
    isopropanol 10.19
    water 1.12
    ethyl acetate 2.8
    n-propanol 9.43
    acetone 7.06
    n-butanol 7.89
    acetonitrile 5.36
    DMF 17.71
    toluene 0.7
    isobutanol 6.68
    1,4-dioxane 7.8
    methyl acetate 4.02
    THF 8.98
    2-butanone 4.38
    n-pentanol 5.02
    sec-butanol 7.59
    n-hexane 0.63
    ethylene glycol 8.32
    NMP 11.59
    cyclohexane 0.46
    DMSO 17.3
    n-butyl acetate 2.88
    n-octanol 3.21
    chloroform 3.7
    n-propyl acetate 2.02
    acetic acid 13.42
    dichloromethane 3.27
    cyclohexanone 5.08
    propylene glycol 7.66
    isopropyl acetate 1.84
    DMAc 9.88
    2-ethoxyethanol 6.76
    isopentanol 6.09
    n-heptane 0.5
    ethyl formate 2.79
    1,2-dichloroethane 2.41
    n-hexanol 5.86
    2-methoxyethanol 12.37
    isobutyl acetate 1.39
    tetrachloromethane 0.88
    n-pentyl acetate 2.0
    transcutol 17.07
    n-heptanol 2.98
    ethylbenzene 0.7
    MIBK 2.55
    2-propoxyethanol 7.65
    tert-butanol 11.34
    MTBE 4.65
    2-butoxyethanol 4.77
    propionic acid 8.11
    o-xylene 0.98
    formic acid 9.02
    diethyl ether 3.7
    m-xylene 0.92
    p-xylene 0.99
    chlorobenzene 1.32
    dimethyl carbonate 1.57
    n-octane 0.24
    formamide 7.92
    cyclopentanone 6.76
    2-pentanone 3.36
    anisole 2.12
    cyclopentyl methyl ether 3.63
    gamma-butyrolactone 8.38
    1-methoxy-2-propanol 8.21
    pyridine 3.33
    3-pentanone 2.4
    furfural 6.42
    n-dodecane 0.25
    diethylene glycol 7.95
    diisopropyl ether 1.11
    tert-amyl alcohol 7.94
    acetylacetone 3.29
    n-hexadecane 0.26
    acetophenone 2.16
    methyl propionate 3.01
    isopentyl acetate 2.63
    trichloroethylene 4.11
    n-nonanol 2.54
    cyclohexanol 4.48
    benzyl alcohol 2.35
    2-ethylhexanol 2.81
    isooctanol 2.36
    dipropyl ether 2.29
    1,2-dichlorobenzene 1.5
    ethyl lactate 2.04
    propylene carbonate 4.24
    n-methylformamide 8.28
    2-pentanol 4.93
    n-pentane 0.66
    1-propoxy-2-propanol 5.41
    1-methoxy-2-propyl acetate 3.05
    2-(2-methoxypropoxy) propanol 4.67
    mesitylene 0.76
    ε-caprolactone 4.57
    p-cymene 0.88
    epichlorohydrin 5.84
    1,1,1-trichloroethane 2.0
    2-aminoethanol 11.1
    morpholine-4-carbaldehyde 8.61
    sulfolane 10.31
    2,2,4-trimethylpentane 0.48
    2-methyltetrahydrofuran 6.09
    n-hexyl acetate 3.36
    isooctane 0.38
    2-(2-butoxyethoxy)ethanol 6.14
    sec-butyl acetate 1.42
    tert-butyl acetate 2.56
    decalin 0.36
    glycerin 9.13
    diglyme 8.9
    acrylic acid 7.51
    isopropyl myristate 1.37
    n-butyric acid 6.48
    acetyl acetate 1.82
    di(2-ethylhexyl) phthalate 1.62
    ethyl propionate 1.76
    nitromethane 11.15
    1,2-diethoxyethane 3.49
    benzonitrile 2.48
    trioctyl phosphate 1.39
    1-bromopropane 1.71
    gamma-valerolactone 7.37
    n-decanol 1.91
    triethyl phosphate 1.37
    4-methyl-2-pentanol 2.93
    propionitrile 3.88
    vinylene carbonate 3.43
    1,1,2-trichlorotrifluoroethane 5.78
    DMS 2.3
    cumene 0.76
    2-octanol 2.04
    2-hexanone 2.54
    octyl acetate 1.84
    limonene 1.37
    1,2-dimethoxyethane 7.72
    ethyl orthosilicate 1.37
    tributyl phosphate 1.56
    diacetone alcohol 4.85
    N,N-dimethylaniline 1.89
    acrylonitrile 4.87
    aniline 2.18
    1,3-propanediol 10.18
    bromobenzene 0.95
    dibromomethane 2.18
    1,1,2,2-tetrachloroethane 3.77
    2-methyl-cyclohexyl acetate 1.96
    tetrabutyl urea 2.16
    diisobutyl methanol 1.75
    2-phenylethanol 2.7
    styrene 0.77
    dioctyl adipate 1.98
    dimethyl sulfate 3.01
    ethyl butyrate 1.93
    methyl lactate 3.15
    butyl lactate 2.33
    diethyl carbonate 1.51
    propanediol butyl ether 5.36
    triethyl orthoformate 1.67
    p-tert-butyltoluene 0.9
    methyl 4-tert-butylbenzoate 2.82
    morpholine 8.82
    tert-butylamine 6.47
    n-dodecanol 1.49
    dimethoxymethane 5.35
    ethylene carbonate 2.72
    cyrene 3.73
    2-ethoxyethyl acetate 2.64
    2-ethylhexyl acetate 1.97
    1,2,4-trichlorobenzene 1.95
    4-methylpyridine 3.13
    dibutyl ether 2.15
    2,6-dimethyl-4-heptanol 1.75
    DEF 4.91
    dimethyl isosorbide 5.13
    tetrachloroethylene 2.62
    eugenol 3.29
    triacetin 2.94
    span 80 4.0
    1,4-butanediol 4.72
    1,1-dichloroethane 2.39
    2-methyl-1-pentanol 4.32
    methyl formate 4.83
    2-methyl-1-butanol 5.76
    n-decane 0.36
    butyronitrile 3.83
    3,7-dimethyl-1-octanol 2.69
    1-chlorooctane 1.31
    1-chlorotetradecane 0.57
    n-nonane 0.36
    undecane 0.29
    tert-butylcyclohexane 0.44
    cyclooctane 0.18
    cyclopentanol 6.05
    tetrahydropyran 5.57
    tert-amyl methyl ether 3.59
    2,5,8-trioxanonane 6.58
    1-hexene 1.75
    2-isopropoxyethanol 4.55
    2,2,2-trifluoroethanol 4.27
    methyl butyrate 2.55

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction