Guanosine Monophosphate

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  • Identifiers

    CAS number
    85-32-5

    Molecular formula
    C10H14N5O8P

    SMILES
    C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N=C(NC2=O)N

  • Odor profile

    Fragrance
    Odorless 91.02%
    Savory 18.13%
    Bitter 16.98%
    Cooked 14.91%
    Milky 14.15%
    Cooling 13.52%
    Clean 13.23%
    Meaty 11.58%
    Burnt 9.91%
    Dairy 9.84%

     

    Flavor
    Bitter 62.42%
    Odorless 59.41%
    Bland 32.54%
    Very mild 27.68%
    Mild 27.33%
    Sweet-like 24.31%
    Yeast 20.66%
    Nitrile 19.22%
    Formyl 19.03%
    Bread crust 18.93%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    -3.5

    pKa est.
    7.08 (neutral)

    Molecular weight
    363.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    3503°C

    Flash point

    • 412.54 ˚C est.

    Solubility expt.

    • Slightly soluble in water, practically insoluble in ethanol
    • 369 mg/mL

  • Synonyms

    • 5'-Guanylic acid
    • 85-32-5
    • guanosine-5'-monophosphate
    • guanosine monophosphate
    • Guanosine 5'-monophosphate
    • guanylic acid
    • 5'-Gmp
    • Guanosine 5'-phosphate
    • Guanidine monophosphate
    • guanylate
    • Guanosine 5'-monophosphoric acid
    • CHEBI:17345
    • guanosine-monophosphate
    • GMP
    • Guanosine 5' Monophosphate
    • guanosine-phosphate
    • Guanosine 5'-phosphoric acid
    • AI3-28539
    • CHEMBL283807
    • E 626
    • Guanosine 5'-(dihydrogen phosphate)
    • [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
    • 16597955EP
    • {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
    • 128952-18-1
    • 5GP
    • Acid, Guanylic
    • ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
    • [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen phosphate
    • {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
    • 5' Guanylic Acid
    • Acid, 5'-Guanylic
    • C10H14N5O8P
    • guanosine-5'-phosphate
    • Monophosphate, Guanosine
    • EINECS 201-598-8
    • guanylsaure
    • 5'-Monophosphate, Guanosine
    • 5'-GMP;5'-guanosine monophosphate
    • 1sgx
    • 2fxv
    • UNII-16597955EP
    • Xylo-GMP
    • (((2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)phosphonic acid
    • (((2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)phosphonic acid
    • ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
    • 1g9t
    • 1qk3
    • Guanosine 5'-phosphorate
    • Epitope ID:190357
    • [3h]guanosine monophosphate
    • SCHEMBL5854
    • 5'-Guanylic acid (Standard)
    • GTPL5123
    • INS NO.626
    • DTXSID9044295
    • SCHEMBL19222125
    • 5'-GUANYLIC ACID [MI]
    • HY-N5134R
    • 5'-Guanylic acid (8CI,9CI)
    • INS-626
    • 1w25
    • guanine riboside-5-phosphoric acid
    • HY-N5134
    • BDBM50010318
    • Guanosine-5'-(dihydrogen phosphate)
    • MFCD00057066
    • AKOS025311571
    • AKOS040744252
    • DB01972
    • Hyaluronic acid, dimethylsilylene ester
    • NG09355
    • 29593-02-0
    • CS-0032523
    • E-626
    • NS00015253
    • C00144
    • Q422473
    • Z2289798741
    • 38CABC90-82D3-4544-9566-34C06A477068
    • Guanosine-5'-monophosphate 1000 microg/mL in Acetonitrile:Water
    • ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyldihydrogenphosphate
    • [(2R,3S,4R,5R)-5-(2-amino-6-hydroxypurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
    • [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

  • Applications

    Guanosine monophosphate (CAS 85-32-5) is primarily used as a biochemical building block and nutritional source in biotech and pharmaceutical workflows; it serves as a substrate and intermediate for nucleotide synthesis, and as a component of cell culture media to support growth in nucleic-acid-based production processes; it is employed as a reagent in analytical and enzymatic assays and as a starting material for nucleotide-derived products in biotech manufacturing; it is also evaluated for use in fermentation nutrient streams and as a research reagent in nucleic acid science, with applications governed by formulation specifics and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.05
    methanol 0.14
    isopropanol 0.05
    water 3.18
    ethyl acetate 0.01
    n-propanol 0.08
    acetone 0.01
    n-butanol 0.06
    acetonitrile 0.03
    DMF 1.19
    toluene 0.0
    isobutanol 0.04
    1,4-dioxane 0.04
    methyl acetate 0.02
    THF 0.11
    2-butanone 0.04
    n-pentanol 0.03
    sec-butanol 0.07
    n-hexane 0.0
    ethylene glycol 0.93
    NMP 5.95
    cyclohexane 0.01
    DMSO 2.68
    n-butyl acetate 0.03
    n-octanol 0.03
    chloroform 0.0
    n-propyl acetate 0.01
    acetic acid 0.37
    dichloromethane 0.01
    cyclohexanone 0.09
    propylene glycol 0.87
    isopropyl acetate 0.0
    DMAc 1.8
    2-ethoxyethanol 0.41
    isopentanol 0.04
    n-heptane 0.01
    ethyl formate 0.03
    1,2-dichloroethane 0.01
    n-hexanol 0.05
    2-methoxyethanol 1.13
    isobutyl acetate 0.0
    tetrachloromethane 0.0
    n-pentyl acetate 0.02
    transcutol 0.29
    n-heptanol 0.07
    ethylbenzene 0.0
    MIBK 0.01
    2-propoxyethanol 0.52
    tert-butanol 0.04
    MTBE 0.01
    2-butoxyethanol 0.4
    propionic acid 0.17
    o-xylene 0.01
    formic acid 5.06
    diethyl ether 0.01
    m-xylene 0.0
    p-xylene 0.0
    chlorobenzene 0.0
    dimethyl carbonate 0.05
    n-octane 0.01
    formamide 3.78
    cyclopentanone 0.16
    2-pentanone 0.02
    anisole 0.01
    cyclopentyl methyl ether 0.04
    gamma-butyrolactone 0.21
    1-methoxy-2-propanol 0.56
    pyridine 0.05
    3-pentanone 0.03
    furfural 0.39
    n-dodecane 0.0
    diethylene glycol 1.38
    diisopropyl ether 0.0
    tert-amyl alcohol 0.06
    acetylacetone 0.01
    n-hexadecane 0.0
    acetophenone 0.02
    methyl propionate 0.03
    isopentyl acetate 0.02
    trichloroethylene 0.01
    n-nonanol 0.03
    cyclohexanol 0.07
    benzyl alcohol 0.02
    2-ethylhexanol 0.03
    isooctanol 0.04
    dipropyl ether 0.05
    1,2-dichlorobenzene 0.0
    ethyl lactate 0.12
    propylene carbonate 0.06
    n-methylformamide 0.66
    2-pentanol 0.03
    n-pentane 0.0
    1-propoxy-2-propanol 0.35
    1-methoxy-2-propyl acetate 0.04
    2-(2-methoxypropoxy) propanol 0.25
    mesitylene 0.0
    ε-caprolactone 0.1
    p-cymene 0.01
    epichlorohydrin 0.05
    1,1,1-trichloroethane 0.0
    2-aminoethanol 0.75
    morpholine-4-carbaldehyde 1.37
    sulfolane 1.75
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 0.05
    n-hexyl acetate 0.02
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 0.33
    sec-butyl acetate 0.01
    tert-butyl acetate 0.01
    decalin 0.0
    glycerin 6.13
    diglyme 0.52
    acrylic acid 0.36
    isopropyl myristate 0.01
    n-butyric acid 0.08
    acetyl acetate 0.0
    di(2-ethylhexyl) phthalate 0.02
    ethyl propionate 0.01
    nitromethane 0.34
    1,2-diethoxyethane 0.03
    benzonitrile 0.01
    trioctyl phosphate 0.03
    1-bromopropane 0.0
    gamma-valerolactone 0.46
    n-decanol 0.03
    triethyl phosphate 0.05
    4-methyl-2-pentanol 0.01
    propionitrile 0.03
    vinylene carbonate 0.05
    1,1,2-trichlorotrifluoroethane 0.72
    DMS 0.02
    cumene 0.0
    2-octanol 0.03
    2-hexanone 0.02
    octyl acetate 0.01
    limonene 0.01
    1,2-dimethoxyethane 0.28
    ethyl orthosilicate 0.04
    tributyl phosphate 0.02
    diacetone alcohol 0.08
    N,N-dimethylaniline 0.01
    acrylonitrile 0.06
    aniline 0.02
    1,3-propanediol 0.54
    bromobenzene 0.0
    dibromomethane 0.0
    1,1,2,2-tetrachloroethane 0.01
    2-methyl-cyclohexyl acetate 0.02
    tetrabutyl urea 0.08
    diisobutyl methanol 0.02
    2-phenylethanol 0.02
    styrene 0.0
    dioctyl adipate 0.01
    dimethyl sulfate 0.21
    ethyl butyrate 0.03
    methyl lactate 0.32
    butyl lactate 0.14
    diethyl carbonate 0.02
    propanediol butyl ether 0.4
    triethyl orthoformate 0.06
    p-tert-butyltoluene 0.01
    methyl 4-tert-butylbenzoate 0.06
    morpholine 0.13
    tert-butylamine 0.01
    n-dodecanol 0.02
    dimethoxymethane 0.17
    ethylene carbonate 0.04
    cyrene 0.63
    2-ethoxyethyl acetate 0.02
    2-ethylhexyl acetate 0.02
    1,2,4-trichlorobenzene 0.0
    4-methylpyridine 0.02
    dibutyl ether 0.02
    2,6-dimethyl-4-heptanol 0.02
    DEF 0.13
    dimethyl isosorbide 0.37
    tetrachloroethylene 0.01
    eugenol 0.13
    triacetin 0.03
    span 80 0.16
    1,4-butanediol 0.24
    1,1-dichloroethane 0.0
    2-methyl-1-pentanol 0.02
    methyl formate 0.23
    2-methyl-1-butanol 0.06
    n-decane 0.0
    butyronitrile 0.02
    3,7-dimethyl-1-octanol 0.01
    1-chlorooctane 0.01
    1-chlorotetradecane 0.0
    n-nonane 0.0
    undecane 0.0
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 0.15
    tetrahydropyran 0.03
    tert-amyl methyl ether 0.02
    2,5,8-trioxanonane 0.42
    1-hexene 0.01
    2-isopropoxyethanol 0.12
    2,2,2-trifluoroethanol 0.54
    methyl butyrate 0.03

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction