Guanidine ferulamide

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  • Identifiers

    CAS number
    292821-68-2

    Molecular formula
    C11H13N3O3

    SMILES
    COC1=C(C=CC(=C1)/C=C/C(=O)N=C(N)N)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 48.38%
    Meaty 38.95%
    Savory 36.75%
    Roasted 28.04%
    Cooked 26.15%
    Spicy 23.13%
    Burnt 22.38%
    Milky 21.32%
    Pungent 20.37%
    Bitter 19.95%

     

    Flavor
    Bitter 48.91%
    Odorless 41.77%
    Mild 24.6%
    Very mild 22.24%
    Nitrile 20.53%
    Bland 20.42%
    Bread crust 20.28%
    Taco 20.09%
    Orange flower 20.02%
    Roasted peanuts 19.5%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.9

    pKa est.
    9.47 (weak base)

    Molecular weight
    235.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    609°C

    Flash point

    • 182.15 ˚C est.

  • Synonyms

    • Guanidine ferulamide
    • O8LSL6YBW5
    • 2-Propenamide, N-(aminoiminomethyl)-3-(4-hydroxy-3-methoxyphenyl)-
    • 292821-68-2
    • UNII-O8LSL6YBW5
    • Guanidine ferulamide [INCI]
    • Q27285488
    • 292821-68-2

  • Applications

    Guanidine ferulamide (CAS 292821-68-2) is a guanidine-containing ferulamide derivative that is commonly used as a building block or intermediate in the synthesis of guanidine-containing compounds for pharmaceutical and specialty-chemical applications. In cosmetics and personal care, the ferulic acid moiety suggests potential antioxidant or stabilizing roles, and the compound may be evaluated for antioxidant or UV-stabilizing activity in ferulic-acid–based formulations. In industrial contexts, it can function as a functional additive or coupling/crosslinking agent in polymers and coatings, enabling incorporation of basic guanidine functionality. It may also act as a chelating or metal-binding component in formulation systems and serve as a research reagent in polymer science and materials development. Its ultimate use is subject to local regulations and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.64
    methanol 6.0
    isopropanol 1.04
    water 0.62
    ethyl acetate 0.69
    n-propanol 1.67
    acetone 1.17
    n-butanol 1.19
    acetonitrile 0.99
    DMF 39.31
    toluene 0.14
    isobutanol 0.87
    1,4-dioxane 0.51
    methyl acetate 0.93
    THF 7.6
    2-butanone 1.7
    n-pentanol 1.02
    sec-butanol 0.92
    n-hexane 0.06
    ethylene glycol 4.76
    NMP 25.01
    cyclohexane 0.02
    DMSO 135.38
    n-butyl acetate 0.75
    n-octanol 0.46
    chloroform 0.72
    n-propyl acetate 0.71
    acetic acid 6.11
    dichloromethane 0.69
    cyclohexanone 2.52
    propylene glycol 5.17
    isopropyl acetate 0.47
    DMAc 54.13
    2-ethoxyethanol 9.42
    isopentanol 0.91
    n-heptane 0.05
    ethyl formate 1.88
    1,2-dichloroethane 0.54
    n-hexanol 0.89
    2-methoxyethanol 20.3
    isobutyl acetate 0.43
    tetrachloromethane 0.19
    n-pentyl acetate 0.51
    transcutol 7.3
    n-heptanol 0.71
    ethylbenzene 0.16
    MIBK 0.88
    2-propoxyethanol 8.43
    tert-butanol 1.18
    MTBE 0.28
    2-butoxyethanol 3.99
    propionic acid 2.47
    o-xylene 0.2
    formic acid 20.59
    diethyl ether 0.29
    m-xylene 0.17
    p-xylene 0.24
    chlorobenzene 0.21
    dimethyl carbonate 2.32
    n-octane 0.03
    formamide 24.07
    cyclopentanone 5.98
    2-pentanone 1.19
    anisole 0.68
    cyclopentyl methyl ether 1.08
    gamma-butyrolactone 7.65
    1-methoxy-2-propanol 9.89
    pyridine 1.44
    3-pentanone 0.99
    furfural 10.41
    n-dodecane 0.02
    diethylene glycol 13.87
    diisopropyl ether 0.09
    tert-amyl alcohol 1.07
    acetylacetone 1.77
    n-hexadecane 0.03
    acetophenone 1.51
    methyl propionate 1.79
    isopentyl acetate 0.86
    trichloroethylene 1.48
    n-nonanol 0.55
    cyclohexanol 0.63
    benzyl alcohol 1.57
    2-ethylhexanol 0.55
    isooctanol 0.58
    dipropyl ether 0.62
    1,2-dichlorobenzene 0.36
    ethyl lactate 2.9
    propylene carbonate 3.08
    n-methylformamide 14.05
    2-pentanol 0.46
    n-pentane 0.03
    1-propoxy-2-propanol 4.57
    1-methoxy-2-propyl acetate 2.14
    2-(2-methoxypropoxy) propanol 5.5
    mesitylene 0.12
    ε-caprolactone 2.57
    p-cymene 0.21
    epichlorohydrin 5.41
    1,1,1-trichloroethane 0.37
    2-aminoethanol 6.98
    morpholine-4-carbaldehyde 14.18
    sulfolane 25.85
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 1.24
    n-hexyl acetate 0.71
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 5.55
    sec-butyl acetate 0.39
    tert-butyl acetate 0.7
    decalin 0.03
    glycerin 16.68
    diglyme 9.2
    acrylic acid 3.78
    isopropyl myristate 0.4
    n-butyric acid 2.74
    acetyl acetate 0.51
    di(2-ethylhexyl) phthalate 1.15
    ethyl propionate 0.88
    nitromethane 10.4
    1,2-diethoxyethane 0.85
    benzonitrile 1.05
    trioctyl phosphate 0.81
    1-bromopropane 0.33
    gamma-valerolactone 11.29
    n-decanol 0.43
    triethyl phosphate 1.29
    4-methyl-2-pentanol 0.37
    propionitrile 1.07
    vinylene carbonate 2.96
    1,1,2-trichlorotrifluoroethane 16.11
    DMS 1.2
    cumene 0.16
    2-octanol 0.33
    2-hexanone 1.1
    octyl acetate 0.59
    limonene 0.25
    1,2-dimethoxyethane 8.44
    ethyl orthosilicate 1.02
    tributyl phosphate 0.95
    diacetone alcohol 3.58
    N,N-dimethylaniline 0.99
    acrylonitrile 2.26
    aniline 0.81
    1,3-propanediol 6.92
    bromobenzene 0.15
    dibromomethane 0.45
    1,1,2,2-tetrachloroethane 1.53
    2-methyl-cyclohexyl acetate 1.15
    tetrabutyl urea 1.74
    diisobutyl methanol 0.34
    2-phenylethanol 1.35
    styrene 0.15
    dioctyl adipate 1.05
    dimethyl sulfate 8.24
    ethyl butyrate 0.94
    methyl lactate 6.4
    butyl lactate 1.9
    diethyl carbonate 0.88
    propanediol butyl ether 3.82
    triethyl orthoformate 1.06
    p-tert-butyltoluene 0.2
    methyl 4-tert-butylbenzoate 2.72
    morpholine 1.98
    tert-butylamine 0.35
    n-dodecanol 0.33
    dimethoxymethane 8.61
    ethylene carbonate 1.77
    cyrene 7.59
    2-ethoxyethyl acetate 1.01
    2-ethylhexyl acetate 0.56
    1,2,4-trichlorobenzene 0.55
    4-methylpyridine 1.37
    dibutyl ether 0.33
    2,6-dimethyl-4-heptanol 0.34
    DEF 3.61
    dimethyl isosorbide 7.89
    tetrachloroethylene 1.07
    eugenol 3.72
    triacetin 1.56
    span 80 3.08
    1,4-butanediol 3.01
    1,1-dichloroethane 0.33
    2-methyl-1-pentanol 0.88
    methyl formate 8.91
    2-methyl-1-butanol 0.95
    n-decane 0.04
    butyronitrile 1.05
    3,7-dimethyl-1-octanol 0.48
    1-chlorooctane 0.13
    1-chlorotetradecane 0.07
    n-nonane 0.03
    undecane 0.03
    tert-butylcyclohexane 0.03
    cyclooctane 0.01
    cyclopentanol 1.27
    tetrahydropyran 0.38
    tert-amyl methyl ether 0.43
    2,5,8-trioxanonane 8.23
    1-hexene 0.24
    2-isopropoxyethanol 3.6
    2,2,2-trifluoroethanol 5.04
    methyl butyrate 1.56

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction