Glyzarin

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  • Identifiers

    CAS number
    62820-28-4

    Molecular formula
    C18H14O4

    SMILES
    CC1=C(C(=O)C2=C(O1)C(=C(C=C2)O)C(=O)C)C3=CC=CC=C3

    Safety labels

  • Odor profile

    Fragrance
    Sweet 47.76%
    Phenolic 46.68%
    Fruity 37.28%
    Floral 36.69%
    Powdery 33.98%
    Burnt 30.72%
    Balsamic 30.7%
    Bitter 29.65%
    Spicy 29.45%
    Dry 28.39%

     

    Flavor
    Bitter 84.05%
    Odorless 21.63%
    Very strong 20.28%
    Lovage 20.25%
    Nitrile 19.99%
    Cedarleaf 19.94%
    Parsley 19.87%
    Broom 19.82%
    Indole 19.82%
    Heather 19.75%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    7.78 (neutral)

    Molecular weight
    294.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    719°C

    Melting point expt.

    • 207 - 208 °C

    Flash point

    • 205.62 ˚C est.

  • Synonyms

    • Glyzarin
    • UNII-IBR4B1Q1E5
    • IBR4B1Q1E5
    • 4H-1-Benzopyran-4-one, 8-acetyl-7-hydroxy-2-methyl-3-phenyl-
    • RefChem:37957
    • 62820-28-4
    • CHEBI:174784
    • DTXSID901194085
    • LMPK12050004
    • 8-Acetyl-7-hydroxy-2-methylisoflavone
    • 2-methyl-7-hydroxy-8-acetyl-isoflavone
    • 8-acetyl-7-hydroxy-2-methyl-3-phenylchromen-4-one
    • Q27280653
    • 8-Acetyl-7-hydroxy-2-methyl-3-phenyl-4H-1-benzopyran-4-one
    • 8-Acetyl-7-hydroxy-2-methyl-3-phenyl-4H-1-benzopyran-4-one, 9CI
    • 62820-28-4

  • Applications

    Glyzarin (CAS 62820-28-4) is commonly evaluated for use in various industrial formulations as an intermediate, solvent, fixative, stabilizer, or odorant component. Potential applications span perfumery/fragrance and cosmetics/personal care as a fragrance carrier or stabilizer; household products as a solvent or formulation additive; industrial manufacturing as a chemical intermediate and processing aid; polymers/plastics as a stabilizer or plasticizer; coatings/inks as a solvent or additive; and cleaning formulations as a solvent-compatible component, with use subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.98
    methanol 3.32
    isopropanol 1.98
    water 0.0
    ethyl acetate 5.35
    n-propanol 3.26
    acetone 14.85
    n-butanol 2.89
    acetonitrile 5.75
    DMF 84.66
    toluene 2.99
    isobutanol 2.89
    1,4-dioxane 31.7
    methyl acetate 9.14
    THF 96.8
    2-butanone 11.86
    n-pentanol 4.01
    sec-butanol 2.18
    n-hexane 0.07
    ethylene glycol 2.19
    NMP 87.51
    cyclohexane 0.09
    DMSO 96.29
    n-butyl acetate 7.75
    n-octanol 3.09
    chloroform 9.25
    n-propyl acetate 9.24
    acetic acid 10.4
    dichloromethane 18.81
    cyclohexanone 31.46
    propylene glycol 2.59
    isopropyl acetate 4.29
    DMAc 62.91
    2-ethoxyethanol 14.67
    isopentanol 3.29
    n-heptane 0.11
    ethyl formate 6.39
    1,2-dichloroethane 15.35
    n-hexanol 3.08
    2-methoxyethanol 29.44
    isobutyl acetate 7.38
    tetrachloromethane 0.37
    n-pentyl acetate 8.07
    transcutol 45.83
    n-heptanol 3.17
    ethylbenzene 1.87
    MIBK 7.15
    2-propoxyethanol 21.62
    tert-butanol 3.29
    MTBE 2.18
    2-butoxyethanol 11.84
    propionic acid 6.23
    o-xylene 1.51
    formic acid 3.89
    diethyl ether 2.23
    m-xylene 1.84
    p-xylene 3.02
    chlorobenzene 5.49
    dimethyl carbonate 8.88
    n-octane 0.08
    formamide 9.89
    cyclopentanone 62.3
    2-pentanone 8.34
    anisole 7.25
    cyclopentyl methyl ether 14.91
    gamma-butyrolactone 70.82
    1-methoxy-2-propanol 17.32
    pyridine 26.07
    3-pentanone 5.84
    furfural 54.47
    n-dodecane 0.16
    diethylene glycol 22.76
    diisopropyl ether 0.69
    tert-amyl alcohol 2.76
    acetylacetone 19.3
    n-hexadecane 0.2
    acetophenone 11.28
    methyl propionate 8.89
    isopentyl acetate 8.56
    trichloroethylene 34.89
    n-nonanol 3.64
    cyclohexanol 4.4
    benzyl alcohol 10.33
    2-ethylhexanol 3.19
    isooctanol 3.29
    dipropyl ether 3.48
    1,2-dichlorobenzene 5.55
    ethyl lactate 7.51
    propylene carbonate 21.23
    n-methylformamide 18.66
    2-pentanol 1.41
    n-pentane 0.03
    1-propoxy-2-propanol 13.15
    1-methoxy-2-propyl acetate 13.91
    2-(2-methoxypropoxy) propanol 16.74
    mesitylene 0.96
    ε-caprolactone 24.87
    p-cymene 1.93
    epichlorohydrin 90.38
    1,1,1-trichloroethane 4.75
    2-aminoethanol 4.08
    morpholine-4-carbaldehyde 80.53
    sulfolane 107.13
    2,2,4-trimethylpentane 0.08
    2-methyltetrahydrofuran 24.99
    n-hexyl acetate 9.56
    isooctane 0.06
    2-(2-butoxyethoxy)ethanol 20.73
    sec-butyl acetate 5.4
    tert-butyl acetate 6.6
    decalin 0.22
    glycerin 9.08
    diglyme 41.58
    acrylic acid 8.71
    isopropyl myristate 4.39
    n-butyric acid 6.65
    acetyl acetate 5.2
    di(2-ethylhexyl) phthalate 7.51
    ethyl propionate 7.14
    nitromethane 33.97
    1,2-diethoxyethane 12.0
    benzonitrile 11.13
    trioctyl phosphate 4.48
    1-bromopropane 3.41
    gamma-valerolactone 92.64
    n-decanol 2.86
    triethyl phosphate 5.56
    4-methyl-2-pentanol 1.57
    propionitrile 5.38
    vinylene carbonate 20.67
    1,1,2-trichlorotrifluoroethane 40.39
    DMS 13.9
    cumene 1.6
    2-octanol 2.34
    2-hexanone 11.41
    octyl acetate 5.72
    limonene 2.42
    1,2-dimethoxyethane 36.6
    ethyl orthosilicate 5.19
    tributyl phosphate 5.64
    diacetone alcohol 13.84
    N,N-dimethylaniline 6.03
    acrylonitrile 11.26
    aniline 6.71
    1,3-propanediol 7.17
    bromobenzene 4.72
    dibromomethane 7.4
    1,1,2,2-tetrachloroethane 20.92
    2-methyl-cyclohexyl acetate 9.37
    tetrabutyl urea 9.33
    diisobutyl methanol 2.32
    2-phenylethanol 9.83
    styrene 2.06
    dioctyl adipate 8.68
    dimethyl sulfate 24.79
    ethyl butyrate 6.61
    methyl lactate 10.27
    butyl lactate 8.44
    diethyl carbonate 5.03
    propanediol butyl ether 10.2
    triethyl orthoformate 6.69
    p-tert-butyltoluene 1.66
    methyl 4-tert-butylbenzoate 12.97
    morpholine 38.1
    tert-butylamine 1.19
    n-dodecanol 2.17
    dimethoxymethane 31.64
    ethylene carbonate 14.45
    cyrene 26.0
    2-ethoxyethyl acetate 15.39
    2-ethylhexyl acetate 6.9
    1,2,4-trichlorobenzene 9.18
    4-methylpyridine 19.49
    dibutyl ether 4.16
    2,6-dimethyl-4-heptanol 2.32
    DEF 15.12
    dimethyl isosorbide 40.02
    tetrachloroethylene 8.71
    eugenol 16.63
    triacetin 13.95
    span 80 12.31
    1,4-butanediol 3.79
    1,1-dichloroethane 5.56
    2-methyl-1-pentanol 4.52
    methyl formate 17.81
    2-methyl-1-butanol 3.1
    n-decane 0.23
    butyronitrile 5.21
    3,7-dimethyl-1-octanol 3.49
    1-chlorooctane 1.72
    1-chlorotetradecane 0.83
    n-nonane 0.17
    undecane 0.19
    tert-butylcyclohexane 0.22
    cyclooctane 0.04
    cyclopentanol 8.57
    tetrahydropyran 14.32
    tert-amyl methyl ether 2.53
    2,5,8-trioxanonane 30.61
    1-hexene 0.71
    2-isopropoxyethanol 10.04
    2,2,2-trifluoroethanol 4.22
    methyl butyrate 10.99

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction