Glycyl tyrosine

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  • Identifiers

    CAS number
    39630-46-1

    Molecular formula
    C11H18N2O6

    SMILES
    C1=CC(=CC=C1C[C@@H](C(=O)O)NC(=O)CN)O.O.O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 72.4%
    Savory 36.58%
    Meaty 24.07%
    Bitter 23.7%
    Sweet 23.23%
    Cooling 21.4%
    Cooked 20.81%
    Milky 20.71%
    Cocoa 16.35%
    Fishy 15.64%

     

    Flavor
    Odorless 64.63%
    Bitter 54.63%
    Mild 36.63%
    Bland 31.07%
    Very mild 23.83%
    Sweet-like 22.92%
    Yeast 21.64%
    Faint 21.45%
    Nitrile 20.78%
    Orange flower 19.59%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.69 (neutral)

    Molecular weight
    274.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    423°C

    Flash point

    • 252.42 ˚C est.

  • Synonyms

    • Glycyl tyrosine
    • 39630-46-1
    • GLYCYL-L-TYROSINE DIHYDRATE
    • L-Tyrosine, glycyl-, dihydrate
    • L-Tyrosine, N-glycyl-, dihydrate
    • UNII-269373P3AW
    • 269373P3AW
    • GLYCYL-TYROSINE DIHYDRATE
    • DTXSID40192736
    • RefChem:143948
    • GLYCYL TYROSINE [INCI]
    • DTXCID80115227
    • Glycyltyrosine dihydrate
    • (2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid;dihydrate
    • (S)-2-(2-Aminoacetamido)-3-(4-hydroxyphenyl)propanoic acid dihydrate
    • n-glycyl-l-tyrosine dihydrate
    • glycyl-l-tyrosin-dihydrat
    • SCHEMBL7103036
    • CHEBI:177941
    • Glycyl-L-tyrosine--water (1/2)
    • HY-W009592A
    • MFCD00673328
    • AKOS030573951
    • CS-15980
    • PD196695
    • CS-0081927
    • D74430
    • F604259
    • Q27254069
    • (2S)-2-[(Aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid dihydrate
    • 39630-46-1

  • Applications

    Glycyl tyrosine (CAS 39630-46-1) is a dipeptide of glycine and tyrosine with several practical applications: as an intermediate in peptide synthesis for pharmaceuticals and biotech; as an analytical standard or assay reagent for peptide analysis by HPLC/LC-MS and proteomics; as a substrate or model compound in enzymology and protease assays; as a building block for peptide libraries and drug discovery; and as a potential cosmetic peptide ingredient for skin-care formulations, used within formulation guidelines.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.2
    methanol 1.17
    isopropanol 0.21
    water 13.38
    ethyl acetate 0.69
    n-propanol 0.12
    acetone 0.48
    n-butanol 0.16
    acetonitrile 0.23
    DMF 36.38
    toluene 0.18
    isobutanol 0.12
    1,4-dioxane 1.59
    methyl acetate 0.38
    THF 2.21
    2-butanone 0.34
    n-pentanol 0.2
    sec-butanol 0.22
    n-hexane 0.05
    ethylene glycol 6.69
    NMP 38.89
    cyclohexane 0.06
    DMSO 29.11
    n-butyl acetate 0.41
    n-octanol 0.14
    chloroform 0.04
    n-propyl acetate 0.36
    acetic acid 8.72
    dichloromethane 0.05
    cyclohexanone 1.48
    propylene glycol 3.51
    isopropyl acetate 0.54
    DMAc 60.74
    2-ethoxyethanol 7.17
    isopentanol 0.29
    n-heptane 0.09
    ethyl formate 0.95
    1,2-dichloroethane 0.08
    n-hexanol 0.42
    2-methoxyethanol 14.47
    isobutyl acetate 0.17
    tetrachloromethane 0.05
    n-pentyl acetate 0.22
    transcutol 6.82
    n-heptanol 0.35
    ethylbenzene 0.19
    MIBK 0.47
    2-propoxyethanol 5.07
    tert-butanol 0.94
    MTBE 0.32
    2-butoxyethanol 2.39
    propionic acid 1.01
    o-xylene 0.33
    formic acid 64.51
    diethyl ether 0.2
    m-xylene 0.22
    p-xylene 0.28
    chlorobenzene 0.07
    dimethyl carbonate 2.05
    n-octane 0.05
    formamide 47.1
    cyclopentanone 2.03
    2-pentanone 0.43
    anisole 0.55
    cyclopentyl methyl ether 0.99
    gamma-butyrolactone 4.16
    1-methoxy-2-propanol 6.74
    pyridine 0.79
    3-pentanone 0.47
    furfural 9.33
    n-dodecane 0.02
    diethylene glycol 17.86
    diisopropyl ether 0.16
    tert-amyl alcohol 0.8
    acetylacetone 2.48
    n-hexadecane 0.03
    acetophenone 1.15
    methyl propionate 0.97
    isopentyl acetate 0.5
    trichloroethylene 0.14
    n-nonanol 0.19
    cyclohexanol 0.56
    benzyl alcohol 0.95
    2-ethylhexanol 0.31
    isooctanol 0.31
    dipropyl ether 0.58
    1,2-dichlorobenzene 0.13
    ethyl lactate 1.84
    propylene carbonate 2.49
    n-methylformamide 7.21
    2-pentanol 0.2
    n-pentane 0.03
    1-propoxy-2-propanol 2.57
    1-methoxy-2-propyl acetate 2.21
    2-(2-methoxypropoxy) propanol 4.4
    mesitylene 0.2
    ε-caprolactone 1.85
    p-cymene 0.22
    epichlorohydrin 1.06
    1,1,1-trichloroethane 0.05
    2-aminoethanol 4.41
    morpholine-4-carbaldehyde 29.17
    sulfolane 16.54
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 0.79
    n-hexyl acetate 0.24
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 4.68
    sec-butyl acetate 0.29
    tert-butyl acetate 0.84
    decalin 0.05
    glycerin 27.66
    diglyme 8.88
    acrylic acid 2.53
    isopropyl myristate 0.18
    n-butyric acid 1.4
    acetyl acetate 0.84
    di(2-ethylhexyl) phthalate 0.59
    ethyl propionate 0.6
    nitromethane 9.02
    1,2-diethoxyethane 0.75
    benzonitrile 0.4
    trioctyl phosphate 0.34
    1-bromopropane 0.04
    gamma-valerolactone 10.56
    n-decanol 0.19
    triethyl phosphate 0.94
    4-methyl-2-pentanol 0.25
    propionitrile 0.17
    vinylene carbonate 1.9
    1,1,2-trichlorotrifluoroethane 8.68
    DMS 0.81
    cumene 0.18
    2-octanol 0.18
    2-hexanone 0.35
    octyl acetate 0.25
    limonene 0.26
    1,2-dimethoxyethane 7.36
    ethyl orthosilicate 0.85
    tributyl phosphate 0.39
    diacetone alcohol 3.72
    N,N-dimethylaniline 0.99
    acrylonitrile 0.44
    aniline 0.59
    1,3-propanediol 3.59
    bromobenzene 0.05
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.21
    2-methyl-cyclohexyl acetate 0.71
    tetrabutyl urea 1.01
    diisobutyl methanol 0.32
    2-phenylethanol 0.89
    styrene 0.16
    dioctyl adipate 0.43
    dimethyl sulfate 7.03
    ethyl butyrate 0.66
    methyl lactate 5.7
    butyl lactate 0.86
    diethyl carbonate 0.6
    propanediol butyl ether 2.46
    triethyl orthoformate 0.97
    p-tert-butyltoluene 0.22
    methyl 4-tert-butylbenzoate 2.03
    morpholine 2.26
    tert-butylamine 0.29
    n-dodecanol 0.17
    dimethoxymethane 5.27
    ethylene carbonate 1.3
    cyrene 9.29
    2-ethoxyethyl acetate 0.6
    2-ethylhexyl acetate 0.34
    1,2,4-trichlorobenzene 0.2
    4-methylpyridine 0.82
    dibutyl ether 0.18
    2,6-dimethyl-4-heptanol 0.32
    DEF 3.79
    dimethyl isosorbide 7.71
    tetrachloroethylene 0.24
    eugenol 2.91
    triacetin 1.18
    span 80 2.52
    1,4-butanediol 2.2
    1,1-dichloroethane 0.03
    2-methyl-1-pentanol 0.35
    methyl formate 5.49
    2-methyl-1-butanol 0.26
    n-decane 0.04
    butyronitrile 0.17
    3,7-dimethyl-1-octanol 0.19
    1-chlorooctane 0.06
    1-chlorotetradecane 0.04
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.03
    cyclooctane 0.04
    cyclopentanol 0.69
    tetrahydropyran 0.4
    tert-amyl methyl ether 0.48
    2,5,8-trioxanonane 9.29
    1-hexene 0.11
    2-isopropoxyethanol 2.75
    2,2,2-trifluoroethanol 6.48
    methyl butyrate 0.87

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction