Glycol oleate

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  • Identifiers

    CAS number
    4500-01-0

    Molecular formula
    C20H38O3

    SMILES
    CCCCCCCC/C=C\CCCCCCCC(=O)OCCO

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fatty 74.09%
    Waxy 64.64%
    Oily 56.28%
    Sweet 31.98%
    Odorless 29.54%
    Creamy 27.5%
    Buttery 24.84%
    Dairy 23.82%
    Milky 20.98%
    Fruity 19.17%

     

    Flavor
    Waxy 59.34%
    Fatty 44.01%
    Oily 39.02%
    Mild 35.26%
    Soapy 32.86%
    Faint 30.18%
    Creamy 28.54%
    Fruity 26.22%
    Fat 25.25%
    Bland 24.08%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.9

    pKa est.
    7.11 (neutral)

    Molecular weight
    326.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    390°C

    Flash point

    • 190.38 ˚C est.

  • Synonyms

    • 2-Hydroxyethyl oleate
    • Glycol oleate
    • 4500-01-0
    • Ethylene glycol monooleate
    • Glycol monooleate
    • 9-Octadecenoic acid (Z)-, 2-hydroxyethyl ester
    • Oleic acid, 2-hydroxyethyl ester
    • 9Z5UXZ64XA
    • 9-Octadecenoic acid (9Z)-, 2-hydroxyethyl ester
    • AEC GLYCOL OLEATE
    • EINECS 224-806-9
    • 9-Octadecenoic acid, 2-hydroxyethyl ester
    • 2-Hydroxyethyl 9-octadecenoate
    • (Z)-9-OCTADECENOIC ACID-2-HYDROXYETHYL ESTER
    • RefChem:663896
    • GLYCOL OLEATE [INCI]
    • 224-806-9
    • 2-hydroxyethyl (Z)-octadec-9-enoate
    • Poly(ethylene glycol) monooleate
    • 9004-96-0
    • 2-hydroxyethyl (9Z)-octadec-9-enoate
    • Cithrol A
    • UNII-9Z5UXZ64XA
    • ethyleneglycol monooleate
    • DSSTox_CID_7713
    • DSSTox_RID_78546
    • DSSTox_GSID_27713
    • SCHEMBL93861
    • SCHEMBL3323202
    • CHEMBL3182752
    • DTXSID0063498
    • Tox21_303475
    • 2-Hydroxyethyl (9Z)-9-octadecenoate #
    • NCGC00257333-01
    • CAS-9004-96-0
    • NS00013716
    • D08973
    • F71263
    • Q27273405
    • 4500-01-0

  • Applications

    Glycol oleate, CAS 4500-01-0, is an ester of oleic acid with ethylene glycol and is primarily used as a nonionic surfactant and emollient in cosmetics and personal care, helping to blend oil- and water-based ingredients, stabilize emulsions, and provide a smooth skin feel and conditioning for hair. It also serves as a secondary surfactant and solvent in household cleaning formulations, improving wetting, dispersion, and fragrance delivery. In industrial manufacturing, glycol oleate can function as a processing aid and lubricant, or as a plasticizer-compatible ester in coating, paint, and polymer systems. It is occasionally evaluated as a solvent component in fragrance formulations or other formulation contexts requiring a glycol ester solvent.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 57.96
    methanol 71.51
    isopropanol 63.13
    water 0.02
    ethyl acetate 221.33
    n-propanol 66.6
    acetone 166.29
    n-butanol 82.74
    acetonitrile 51.62
    DMF 212.19
    toluene 68.23
    isobutanol 64.23
    1,4-dioxane 240.14
    methyl acetate 124.91
    THF 625.93
    2-butanone 192.45
    n-pentanol 77.02
    sec-butanol 82.11
    n-hexane 17.48
    ethylene glycol 3.97
    NMP 391.55
    cyclohexane 89.35
    DMSO 503.48
    n-butyl acetate 232.87
    n-octanol 65.29
    chloroform 418.87
    n-propyl acetate 289.71
    acetic acid 73.53
    dichloromethane 495.99
    cyclohexanone 546.96
    propylene glycol 14.49
    isopropyl acetate 219.73
    DMAc 435.27
    2-ethoxyethanol 175.94
    isopentanol 119.07
    n-heptane 18.06
    ethyl formate 86.54
    1,2-dichloroethane 405.58
    n-hexanol 64.72
    2-methoxyethanol 166.57
    isobutyl acetate 182.26
    tetrachloromethane 93.74
    n-pentyl acetate 304.95
    transcutol 962.1
    n-heptanol 62.02
    ethylbenzene 62.23
    MIBK 241.41
    2-propoxyethanol 164.2
    tert-butanol 139.53
    MTBE 207.58
    2-butoxyethanol 172.8
    propionic acid 65.9
    o-xylene 71.02
    formic acid 14.8
    diethyl ether 159.99
    m-xylene 63.02
    p-xylene 83.26
    chlorobenzene 116.43
    dimethyl carbonate 44.81
    n-octane 9.88
    formamide 34.02
    cyclopentanone 475.4
    2-pentanone 250.1
    anisole 148.13
    cyclopentyl methyl ether 306.66
    gamma-butyrolactone 380.82
    1-methoxy-2-propanol 180.46
    pyridine 207.94
    3-pentanone 177.96
    furfural 287.72
    n-dodecane 6.42
    diethylene glycol 64.89
    diisopropyl ether 73.6
    tert-amyl alcohol 147.75
    acetylacetone 300.53
    n-hexadecane 7.77
    acetophenone 190.24
    methyl propionate 143.92
    isopentyl acetate 235.17
    trichloroethylene 576.0
    n-nonanol 65.85
    cyclohexanol 165.11
    benzyl alcohol 89.2
    2-ethylhexanol 74.32
    isooctanol 71.15
    dipropyl ether 153.76
    1,2-dichlorobenzene 155.58
    ethyl lactate 90.67
    propylene carbonate 215.2
    n-methylformamide 64.01
    2-pentanol 75.4
    n-pentane 12.35
    1-propoxy-2-propanol 177.94
    1-methoxy-2-propyl acetate 236.67
    2-(2-methoxypropoxy) propanol 167.67
    mesitylene 54.36
    ε-caprolactone 444.52
    p-cymene 51.68
    epichlorohydrin 509.38
    1,1,1-trichloroethane 363.24
    2-aminoethanol 19.52
    morpholine-4-carbaldehyde 331.54
    sulfolane 673.62
    2,2,4-trimethylpentane 17.24
    2-methyltetrahydrofuran 420.53
    n-hexyl acetate 276.15
    isooctane 10.25
    2-(2-butoxyethoxy)ethanol 249.89
    sec-butyl acetate 212.95
    tert-butyl acetate 311.53
    decalin 34.37
    glycerin 27.49
    diglyme 578.29
    acrylic acid 40.56
    isopropyl myristate 86.53
    n-butyric acid 184.54
    acetyl acetate 136.65
    di(2-ethylhexyl) phthalate 70.06
    ethyl propionate 212.33
    nitromethane 185.11
    1,2-diethoxyethane 340.2
    benzonitrile 109.34
    trioctyl phosphate 52.87
    1-bromopropane 211.19
    gamma-valerolactone 602.64
    n-decanol 42.09
    triethyl phosphate 110.28
    4-methyl-2-pentanol 65.87
    propionitrile 69.05
    vinylene carbonate 150.57
    1,1,2-trichlorotrifluoroethane 315.42
    DMS 127.52
    cumene 51.15
    2-octanol 57.34
    2-hexanone 244.97
    octyl acetate 103.84
    limonene 98.33
    1,2-dimethoxyethane 414.19
    ethyl orthosilicate 117.79
    tributyl phosphate 75.13
    diacetone alcohol 275.72
    N,N-dimethylaniline 111.94
    acrylonitrile 64.71
    aniline 75.47
    1,3-propanediol 51.46
    bromobenzene 142.64
    dibromomethane 315.52
    1,1,2,2-tetrachloroethane 601.41
    2-methyl-cyclohexyl acetate 189.82
    tetrabutyl urea 119.26
    diisobutyl methanol 61.45
    2-phenylethanol 84.19
    styrene 71.15
    dioctyl adipate 152.44
    dimethyl sulfate 117.58
    ethyl butyrate 222.98
    methyl lactate 63.27
    butyl lactate 174.54
    diethyl carbonate 116.54
    propanediol butyl ether 136.97
    triethyl orthoformate 174.66
    p-tert-butyltoluene 49.52
    methyl 4-tert-butylbenzoate 197.3
    morpholine 360.69
    tert-butylamine 86.28
    n-dodecanol 29.7
    dimethoxymethane 182.45
    ethylene carbonate 146.61
    cyrene 173.07
    2-ethoxyethyl acetate 333.43
    2-ethylhexyl acetate 189.21
    1,2,4-trichlorobenzene 182.57
    4-methylpyridine 206.45
    dibutyl ether 178.96
    2,6-dimethyl-4-heptanol 61.45
    DEF 305.38
    dimethyl isosorbide 359.06
    tetrachloroethylene 362.14
    eugenol 156.85
    triacetin 280.08
    span 80 155.42
    1,4-butanediol 22.73
    1,1-dichloroethane 278.32
    2-methyl-1-pentanol 104.07
    methyl formate 42.98
    2-methyl-1-butanol 99.3
    n-decane 14.5
    butyronitrile 104.13
    3,7-dimethyl-1-octanol 81.19
    1-chlorooctane 72.18
    1-chlorotetradecane 22.02
    n-nonane 13.98
    undecane 8.97
    tert-butylcyclohexane 23.76
    cyclooctane 20.18
    cyclopentanol 135.58
    tetrahydropyran 409.81
    tert-amyl methyl ether 182.64
    2,5,8-trioxanonane 331.72
    1-hexene 57.07
    2-isopropoxyethanol 156.69
    2,2,2-trifluoroethanol 30.8
    methyl butyrate 319.25

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction