Glycine, N-(2-hydroxyethyl)-N-[2-[(1-oxododecyl)amino]ethyl]-, monosodium salt

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  • Identifiers

    CAS number
    66161-62-4

    Molecular formula
    C18H35N2NaO4

    SMILES
    CCCCCCCCCCCC(=O)NCCN(CCO)CC(=O)[O-].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 43.74%
    Savory 36.5%
    Fishy 34.14%
    Meaty 29.27%
    Cooling 28.71%
    Oily 24.46%
    Animal 23.77%
    Fatty 20.67%
    Waxy 20.36%
    Sweet 20.26%

     

    Flavor
    Odorless 46.63%
    Bland 37.49%
    Mild 33.39%
    Faint 22.47%
    Slightly waxy 20.68%
    Sweet-like 20.67%
    Bitter 20.59%
    Bay oil 20.3%
    Cultured dairy 19.69%
    Cedarleaf 19.51%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.39 (weak acid)

    Molecular weight
    366.5 g/mol

    Flash point

    • 233.4 ˚C est.

  • Synonyms

    • 66161-62-4
    • Glycine, N-(2-hydroxyethyl)-N-[2-[(1-oxododecyl)amino]ethyl]-, monosodium salt
    • SLK428451L
    • Glycine, N-(2-hydroxyethyl)-N-(2-((1-oxododecyl)amino)ethyl)-, monosodium salt
    • Glycine, N-(2-hydroxyethyl)-N-(2-((1-oxododecyl)amino)ethyl)-, sodium salt (1:1)
    • sodium;2-[2-(dodecanoylamino)ethyl-(2-hydroxyethyl)amino]acetate
    • UNII-SLK428451L
    • EINECS 266-197-2
    • COLATERIC SLAA
    • MIRANOL HMA
    • AMPHOSOL 1L
    • STEINAPON AM 2L
    • MACKAM 1L
    • JEETERIC LMM-30
    • EMPIGEN CDL 30
    • CRODATERIC LA 30
    • MACKAM HPL-28
    • MIRANOL ULTRA L-32
    • SCHEMBL1664566
    • DTXSID8070417
    • 2-Laurylamido-N-hydroxyethyl-N-(sodium carboxymethyl)ethylamine
    • Sodium N-(2-hydroxyethyl)-N-(2-((1-oxododecyl)amino)ethyl)glycinate
    • Sodium [(2-dodecanamidoethyl)(2-hydroxyethyl)amino]acetate
    • GLYCINE, N-2-HYDROXYETHYL-N-2-LAURAMIDOETHYL-, SODIUM SALT
    • Glycine, N-(2-hydroxyethyl)-N-[2-[(1-oxododecyl)amino]ethyl]-, sodium salt
    • Glycine,N-(2-hydroxyethyl)-N-[2-[(1-oxododecyl)amino]ethyl]-,sodium salt(1:1)
    • N-(2-Hydroxyethyl)-N-[2-[(1-oxododecyl)amino]ethyl]-glycine monosodium salt
    • 66161-62-4

  • Applications

    Glycine, N-(2-hydroxyethyl)-N-[2-[(1-oxododecyl)amino]ethyl]-, monosodium salt (CAS 66161-62-4) is a glycine-derived monosodium salt that functions as an amphoteric surfactant. In real-world formulations, it may be used as an amphoteric surfactant and conditioning/cleansing agent in cosmetics and personal care products; as a dispersant, emulsifier, and foam stabilizer in household and industrial cleaners; as a wetting agent and pigment dispersant in coatings and inks; as a processing aid or stabilizer in polymer and plastics processing; and as an adjuvant in agricultural formulations to improve spray coverage and uniformity of actives. It may also serve as an intermediate in the synthesis of other specialty surfactants and conditioning ingredients. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 26.3
    methanol 146.36
    isopropanol 7.68
    water 10.69
    ethyl acetate 9.49
    n-propanol 16.34
    acetone 18.37
    n-butanol 10.61
    acetonitrile 6.22
    DMF 122.45
    toluene 4.36
    isobutanol 10.1
    1,4-dioxane 17.81
    methyl acetate 9.4
    THF 44.16
    2-butanone 12.97
    n-pentanol 11.17
    sec-butanol 7.99
    n-hexane 0.31
    ethylene glycol 32.98
    NMP 265.1
    cyclohexane 0.77
    DMSO 295.3
    n-butyl acetate 7.84
    n-octanol 5.43
    chloroform 13.76
    n-propyl acetate 10.13
    acetic acid 116.2
    dichloromethane 19.25
    cyclohexanone 57.02
    propylene glycol 37.36
    isopropyl acetate 9.2
    DMAc 200.57
    2-ethoxyethanol 55.46
    isopentanol 9.64
    n-heptane 0.32
    ethyl formate 14.24
    1,2-dichloroethane 15.47
    n-hexanol 5.76
    2-methoxyethanol 97.97
    isobutyl acetate 7.21
    tetrachloromethane 3.53
    n-pentyl acetate 11.4
    transcutol 159.96
    n-heptanol 6.76
    ethylbenzene 3.29
    MIBK 10.32
    2-propoxyethanol 36.01
    tert-butanol 10.71
    MTBE 3.75
    2-butoxyethanol 30.89
    propionic acid 38.15
    o-xylene 6.61
    formic acid 188.23
    diethyl ether 2.38
    m-xylene 5.76
    p-xylene 4.83
    chlorobenzene 6.3
    dimethyl carbonate 11.2
    n-octane 0.26
    formamide 181.82
    cyclopentanone 64.63
    2-pentanone 11.42
    anisole 7.22
    cyclopentyl methyl ether 18.04
    gamma-butyrolactone 93.23
    1-methoxy-2-propanol 51.18
    pyridine 21.8
    3-pentanone 9.87
    furfural 91.43
    n-dodecane 0.24
    diethylene glycol 53.13
    diisopropyl ether 1.44
    tert-amyl alcohol 11.13
    acetylacetone 28.99
    n-hexadecane 0.27
    acetophenone 18.61
    methyl propionate 14.0
    isopentyl acetate 8.73
    trichloroethylene 28.84
    n-nonanol 5.54
    cyclohexanol 18.31
    benzyl alcohol 17.72
    2-ethylhexanol 4.27
    isooctanol 5.98
    dipropyl ether 3.32
    1,2-dichlorobenzene 8.76
    ethyl lactate 18.64
    propylene carbonate 44.11
    n-methylformamide 64.71
    2-pentanol 4.6
    n-pentane 0.23
    1-propoxy-2-propanol 22.76
    1-methoxy-2-propyl acetate 21.0
    2-(2-methoxypropoxy) propanol 33.69
    mesitylene 4.12
    ε-caprolactone 57.25
    p-cymene 3.1
    epichlorohydrin 49.31
    1,1,1-trichloroethane 9.2
    2-aminoethanol 61.69
    morpholine-4-carbaldehyde 128.58
    sulfolane 224.84
    2,2,4-trimethylpentane 0.41
    2-methyltetrahydrofuran 19.68
    n-hexyl acetate 11.94
    isooctane 0.23
    2-(2-butoxyethoxy)ethanol 47.03
    sec-butyl acetate 7.24
    tert-butyl acetate 13.82
    decalin 0.77
    glycerin 94.12
    diglyme 78.08
    acrylic acid 47.32
    isopropyl myristate 4.45
    n-butyric acid 38.88
    acetyl acetate 12.95
    di(2-ethylhexyl) phthalate 11.19
    ethyl propionate 9.18
    nitromethane 95.51
    1,2-diethoxyethane 13.5
    benzonitrile 12.6
    trioctyl phosphate 6.84
    1-bromopropane 3.93
    gamma-valerolactone 131.8
    n-decanol 3.82
    triethyl phosphate 9.45
    4-methyl-2-pentanol 4.11
    propionitrile 5.95
    vinylene carbonate 37.63
    1,1,2-trichlorotrifluoroethane 103.06
    DMS 17.8
    cumene 3.26
    2-octanol 3.97
    2-hexanone 10.13
    octyl acetate 6.61
    limonene 4.06
    1,2-dimethoxyethane 40.32
    ethyl orthosilicate 8.79
    tributyl phosphate 8.66
    diacetone alcohol 34.17
    N,N-dimethylaniline 9.53
    acrylonitrile 12.24
    aniline 12.35
    1,3-propanediol 51.51
    bromobenzene 5.24
    dibromomethane 9.47
    1,1,2,2-tetrachloroethane 27.83
    2-methyl-cyclohexyl acetate 12.37
    tetrabutyl urea 14.39
    diisobutyl methanol 2.89
    2-phenylethanol 12.19
    styrene 3.16
    dioctyl adipate 12.53
    dimethyl sulfate 41.25
    ethyl butyrate 8.27
    methyl lactate 32.15
    butyl lactate 22.5
    diethyl carbonate 6.29
    propanediol butyl ether 39.38
    triethyl orthoformate 9.41
    p-tert-butyltoluene 3.05
    methyl 4-tert-butylbenzoate 28.45
    morpholine 35.29
    tert-butylamine 3.36
    n-dodecanol 2.71
    dimethoxymethane 29.85
    ethylene carbonate 30.16
    cyrene 56.54
    2-ethoxyethyl acetate 21.7
    2-ethylhexyl acetate 6.99
    1,2,4-trichlorobenzene 12.61
    4-methylpyridine 18.53
    dibutyl ether 3.52
    2,6-dimethyl-4-heptanol 2.89
    DEF 32.37
    dimethyl isosorbide 57.9
    tetrachloroethylene 22.8
    eugenol 29.71
    triacetin 34.29
    span 80 29.83
    1,4-butanediol 26.08
    1,1-dichloroethane 6.81
    2-methyl-1-pentanol 10.64
    methyl formate 37.8
    2-methyl-1-butanol 10.47
    n-decane 0.4
    butyronitrile 6.19
    3,7-dimethyl-1-octanol 4.98
    1-chlorooctane 2.08
    1-chlorotetradecane 0.9
    n-nonane 0.33
    undecane 0.3
    tert-butylcyclohexane 0.57
    cyclooctane 0.38
    cyclopentanol 24.07
    tetrahydropyran 11.38
    tert-amyl methyl ether 5.21
    2,5,8-trioxanonane 57.79
    1-hexene 1.27
    2-isopropoxyethanol 28.46
    2,2,2-trifluoroethanol 59.59
    methyl butyrate 14.77

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction