Glyceryl monoacetate

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  • Identifiers

    CAS number
    106-61-6

    Molecular formula
    C5H10O4

    SMILES
    CC(=O)OCC(CO)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 54.49%
    Odorless 44.63%
    Ethereal 39.29%
    Buttery 32.84%
    Caramellic 31.94%
    Alcoholic 28.29%
    Sweet 25.74%
    Winey 25.27%
    Milky 24.09%
    Solvent 21.64%

     

    Flavor
    Odorless 52.05%
    Sweet 48.02%
    Fruity 46.49%
    Bitter 34.65%
    Creamy 34.33%
    Buttery 33.04%
    Mild 30.93%
    Fruit 28.12%
    Sweet-like 26.61%
    Musty 26.48%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.0

    pKa est.
    7.51 (neutral)

    Molecular weight
    134.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • FP: -78 °C

    Boiling point

    • 316 °F at 16.5 mmHg (NTP, 1992)
    • 129-131 °C @ 3 MM HG

    Flash point

    • 136.33 ˚C est.
    • greater than 201.2 °F (NTP, 1992)

    Solubility expt.

    • greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)
    • SOL IN WATER, ALCOHOL, SLIGHTLY IN ETHER; INSOL IN BENZENE

  • Synonyms

    • 2,3-Dihydroxypropyl acetate
    • 1-Monoacetin
    • Monoacetin
    • 106-61-6
    • Acetin
    • 26446-35-5
    • Glycerol monoacetate
    • Glyceryl monoacetate
    • Acetoglyceride
    • Glyceryl acetate
    • ACETIN, 1-MONO-
    • Monoacetyl glycerine
    • Glycerol acetate
    • 1,2,3-Propanetriol, 1-acetate
    • Acetin, mono-
    • Glycerol 1-monoacetate
    • Glyceryl 1-monoacetate
    • Glyceryl 1-acetate
    • Monacetin
    • Glycerine 1-acetate
    • 1,2,3-Propanetriol, acetate
    • Acetic acid, monoglyceride
    • Mono-acetin
    • alpha-Monoacetin
    • .alpha.-Monoacetin
    • Acetyl monoglyceride
    • Glycerin monoacetate
    • Glycerine monoacetate
    • 1335-58-6
    • Glycerol alpha-monoacetate
    • Glycerol 1-acetate
    • Glycerol .alpha.-monoacetate
    • NSC 35010
    • CCRIS 5881
    • HSDB 4285
    • 1,2,3,-Propanetriol monoacetate
    • (+-)-2,3-Dihydroxypropyl acetate
    • 93713-40-7
    • EINECS 203-415-7
    • EINECS 247-704-6
    • 1NA86SF2H2
    • AI3-24158
    • EINECS 215-637-1
    • NSC-35010
    • 1-MONOACETIN [USP IMPURITY]
    • (+/-)-2,3-DIHYDROXYPROPYL ACETATE
    • Glycerol, 1-acetate
    • 1-MONOACETIN (USP IMPURITY)
    • Glycerol 1-Acetate (Technical grade)
    • MONOACETOGLYCERIDE
    • UNII-1NA86SF2H2
    • UNII-84IK99H5ZH
    • alphaMonoacetin
    • Acetin, mono
    • Acetin, 1mono
    • Glycerine 1acetate
    • Glycerol, 1acetate
    • Monoacetin-technical
    • acetyl glyceryl ether
    • Glycerol 1monoacetate
    • Glyceryl 1monoacetate
    • Glycerol alphamonoacetate
    • 1-MONO-ACETIN
    • MONOACETIN [HSDB]
    • 2,3Dihydroxypropyl acetate
    • WLN: Q1YQ1OV1
    • EASTMAN 9-45
    • SCHEMBL33457
    • 1,2,3-Propanetriol,acetate
    • 1,3-Propanetriol, 1-acetate
    • Acetic acid, monoglyceraldehyde
    • 84IK99H5ZH
    • GLYCERYL ACETATE [INCI]
    • 1,2,3,Propanetriol monoacetate
    • 1,2,3Propanetriol, monoacetate
    • DTXSID4041579
    • DTXSID5024396
    • MAG 2:0
    • DTXCID901323290
    • Glycerine 1-acetate; 1-Monoacetin
    • NSC35010
    • MFCD00036185
    • MG 2:0
    • AKOS027320964
    • SB84223
    • (.+/-.)-2,3-Dihydroxypropyl acetate
    • acetic acid 2,3-dihydroxy-propyl ester
    • 1,2,3-Propanetriol, 1-acetate (9CI)
    • AS-44339
    • FD167339
    • FM159268
    • Monoacetin (contains Di-,Tri-, Glycerol)
    • NS00020920
    • A10893
    • A902062
    • Q27252646
    • 203-415-7

  • Applications

    Glyceryl monoacetate, CAS 106-61-6, is used primarily as an emollient and solvent in cosmetics and personal care; as a plasticizer and solvent for polymer and coating systems such as vinyl and cellulose derivatives, improving flexibility and processability; as a processing aid and plasticizer in inks and adhesives; serves as an intermediate in the synthesis of glyceride esters and other acyl glycerol derivatives; may function as a carrier for fragrance ingredients or aroma components in fragrance applications; all uses are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 153.82
    methanol 398.92
    isopropanol 84.95
    water 1270.04
    ethyl acetate 13.97
    n-propanol 85.51
    acetone 56.51
    n-butanol 61.12
    acetonitrile 43.76
    DMF 864.97
    toluene 2.97
    isobutanol 50.9
    1,4-dioxane 116.4
    methyl acetate 23.92
    THF 83.91
    2-butanone 24.54
    n-pentanol 31.06
    sec-butanol 51.59
    n-hexane 1.89
    ethylene glycol 350.44
    NMP 419.39
    cyclohexane 4.94
    DMSO 732.71
    n-butyl acetate 6.36
    n-octanol 15.45
    chloroform 11.18
    n-propyl acetate 9.06
    acetic acid 196.12
    dichloromethane 24.09
    cyclohexanone 49.42
    propylene glycol 217.81
    isopropyl acetate 8.13
    DMAc 542.72
    2-ethoxyethanol 138.67
    isopentanol 36.97
    n-heptane 2.78
    ethyl formate 59.91
    1,2-dichloroethane 20.25
    n-hexanol 17.06
    2-methoxyethanol 351.2
    isobutyl acetate 5.2
    tetrachloromethane 3.26
    n-pentyl acetate 6.29
    transcutol 108.51
    n-heptanol 12.98
    ethylbenzene 3.64
    MIBK 10.38
    2-propoxyethanol 61.53
    tert-butanol 85.76
    MTBE 20.4
    2-butoxyethanol 40.75
    propionic acid 89.99
    o-xylene 7.7
    formic acid 574.44
    diethyl ether 13.0
    m-xylene 4.38
    p-xylene 5.26
    chlorobenzene 4.83
    dimethyl carbonate 23.31
    n-octane 1.33
    formamide 454.6
    cyclopentanone 64.57
    2-pentanone 16.03
    anisole 15.88
    cyclopentyl methyl ether 22.61
    gamma-butyrolactone 96.6
    1-methoxy-2-propanol 146.52
    pyridine 29.57
    3-pentanone 13.73
    furfural 142.9
    n-dodecane 1.15
    diethylene glycol 132.29
    diisopropyl ether 3.95
    tert-amyl alcohol 57.94
    acetylacetone 24.32
    n-hexadecane 1.22
    acetophenone 18.86
    methyl propionate 23.69
    isopentyl acetate 6.49
    trichloroethylene 22.38
    n-nonanol 13.27
    cyclohexanol 44.76
    benzyl alcohol 28.72
    2-ethylhexanol 10.16
    isooctanol 10.44
    dipropyl ether 9.64
    1,2-dichlorobenzene 7.52
    ethyl lactate 26.13
    propylene carbonate 42.07
    n-methylformamide 339.07
    2-pentanol 22.99
    n-pentane 2.6
    1-propoxy-2-propanol 35.19
    1-methoxy-2-propyl acetate 14.46
    2-(2-methoxypropoxy) propanol 50.51
    mesitylene 4.38
    ε-caprolactone 47.86
    p-cymene 4.45
    epichlorohydrin 68.06
    1,1,1-trichloroethane 5.98
    2-aminoethanol 305.77
    morpholine-4-carbaldehyde 329.8
    sulfolane 199.85
    2,2,4-trimethylpentane 1.67
    2-methyltetrahydrofuran 39.29
    n-hexyl acetate 11.2
    isooctane 0.93
    2-(2-butoxyethoxy)ethanol 58.12
    sec-butyl acetate 5.38
    tert-butyl acetate 9.71
    decalin 2.02
    glycerin 413.71
    diglyme 114.21
    acrylic acid 120.04
    isopropyl myristate 5.57
    n-butyric acid 60.95
    acetyl acetate 10.85
    di(2-ethylhexyl) phthalate 13.28
    ethyl propionate 11.78
    nitromethane 207.2
    1,2-diethoxyethane 15.38
    benzonitrile 18.0
    trioctyl phosphate 9.32
    1-bromopropane 7.59
    gamma-valerolactone 148.51
    n-decanol 10.21
    triethyl phosphate 11.39
    4-methyl-2-pentanol 12.14
    propionitrile 25.86
    vinylene carbonate 51.28
    1,1,2-trichlorotrifluoroethane 125.98
    DMS 12.52
    cumene 4.15
    2-octanol 7.7
    2-hexanone 10.41
    octyl acetate 8.3
    limonene 7.0
    1,2-dimethoxyethane 159.3
    ethyl orthosilicate 10.46
    tributyl phosphate 9.45
    diacetone alcohol 34.69
    N,N-dimethylaniline 22.63
    acrylonitrile 48.95
    aniline 18.14
    1,3-propanediol 239.36
    bromobenzene 3.19
    dibromomethane 12.11
    1,1,2,2-tetrachloroethane 22.31
    2-methyl-cyclohexyl acetate 10.58
    tetrabutyl urea 19.07
    diisobutyl methanol 7.43
    2-phenylethanol 14.93
    styrene 3.83
    dioctyl adipate 13.1
    dimethyl sulfate 66.9
    ethyl butyrate 9.5
    methyl lactate 65.0
    butyl lactate 16.26
    diethyl carbonate 8.06
    propanediol butyl ether 53.72
    triethyl orthoformate 10.79
    p-tert-butyltoluene 4.3
    methyl 4-tert-butylbenzoate 25.72
    morpholine 150.58
    tert-butylamine 36.93
    n-dodecanol 8.19
    dimethoxymethane 127.86
    ethylene carbonate 36.86
    cyrene 76.53
    2-ethoxyethyl acetate 11.05
    2-ethylhexyl acetate 5.02
    1,2,4-trichlorobenzene 9.29
    4-methylpyridine 28.32
    dibutyl ether 7.65
    2,6-dimethyl-4-heptanol 7.43
    DEF 92.76
    dimethyl isosorbide 56.25
    tetrachloroethylene 15.73
    eugenol 34.62
    triacetin 19.67
    span 80 39.63
    1,4-butanediol 106.77
    1,1-dichloroethane 8.82
    2-methyl-1-pentanol 23.72
    methyl formate 196.76
    2-methyl-1-butanol 40.22
    n-decane 1.63
    butyronitrile 27.11
    3,7-dimethyl-1-octanol 12.86
    1-chlorooctane 4.22
    1-chlorotetradecane 2.3
    n-nonane 1.6
    undecane 1.31
    tert-butylcyclohexane 1.58
    cyclooctane 2.13
    cyclopentanol 66.26
    tetrahydropyran 36.71
    tert-amyl methyl ether 18.56
    2,5,8-trioxanonane 94.88
    1-hexene 3.91
    2-isopropoxyethanol 55.12
    2,2,2-trifluoroethanol 121.56
    methyl butyrate 21.1

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction