Glyceryl 1-monopropionate

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  • Identifiers

    CAS number
    624-47-5

    Molecular formula
    C6H12O4

    SMILES
    CCC(=O)OCC(CO)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 60.85%
    Buttery 39.84%
    Caramellic 39.52%
    Ethereal 38.73%
    Odorless 34.47%
    Winey 31.33%
    Oily 28.74%
    Sweet 27.12%
    Milky 26.02%
    Fatty 25.29%

     

    Flavor
    Sweet 54.96%
    Fruity 49.51%
    Odorless 45.75%
    Creamy 36.02%
    Bitter 32.15%
    Buttery 30.98%
    Musty 29.53%
    Waxy 29.04%
    Fruit 28.58%
    Mild 28.07%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.5

    pKa est.
    7.4 (neutral)

    Molecular weight
    148.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    280°C

    Flash point

    • 133.14 ˚C est.

  • Synonyms

    • 2,3-dihydroxypropyl propanoate
    • glyceryl 1-monopropionate
    • 1-MONOPROPIONIN
    • NSC-35011
    • PROPIONIN, 1-MONO-
    • 1-O-PROPANOYLGLYCEROL
    • AALUCPRYHRPMAG-UHFFFAOYSA-
    • GLYCEROL 1-MONOPROPIONATE
    • DTXSID60949688
    • V1056EB2A8
    • 1,2,3-Propanetriol, 1-propanoate
    • GLYCEROL .ALPHA.-MONOPROPIONATE
    • RefChem:663497
    • DTXCID601506027
    • DTXCID801377870
    • GLYCEROL ALPHA-MONOPROPIONATE
    • 873-553-6
    • DTXSID201020986
    • InChI=1/C6H12O4/c1-2-6(9)10-4-5(8)3-7/h5,7-8H,2-4H2,1H3
    • 2,3-Dihydroxypropyl propionate
    • Glycerol propionate
    • Alpha-monopropionin
    • 624-47-5
    • 26894-50-8
    • 1,2,3-PROPANETRIOL 1-PROPANOATE
    • Glycerol 1-propanoate
    • propionin
    • glyceryl monopropionate
    • 1-Mono propionin
    • EINECS 248-091-8
    • glycerol monopropionate
    • 1-Monopropionin, 8CI
    • SCHEMBL374426
    • SCHEMBL1381508
    • SCHEMBL1408649
    • SCHEMBL11473185
    • SCHEMBL11847401
    • UNII-C4122110QD
    • MAG 3:0
    • 2,3-Dihydroxypropyl propionate #
    • CHEBI:173631
    • NSC35011
    • MG 3:0
    • C4122110QD
    • EN300-7655326
    • Q27291388
    • 624-47-5

  • Applications

    Glyceryl 1-monopropionate (CAS 624-47-5) is the propionate ester of glycerol and is used across industries as an additive, processing aid, and intermediate. In polymer and coating formulations, it can act as a plasticizer and softener for certain systems; in fragrance and cosmetic applications, it is commonly employed as a solvent and processing aid for fragrance ingredients and active components, and may function as an emulsifier or co-surfactant in cosmetic formulations. It can serve as an intermediate in the synthesis of propionate esters and related fragrance ingredients. In cleaning formulations, it may be used as a solvent or formulation aid. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 623.83
    methanol 1680.96
    isopropanol 345.01
    water 729.12
    ethyl acetate 62.23
    n-propanol 346.36
    acetone 312.85
    n-butanol 251.23
    acetonitrile 198.11
    DMF 1676.33
    toluene 12.17
    isobutanol 207.44
    1,4-dioxane 350.7
    methyl acetate 99.42
    THF 303.05
    2-butanone 117.51
    n-pentanol 141.15
    sec-butanol 207.17
    n-hexane 4.67
    ethylene glycol 642.45
    NMP 749.53
    cyclohexane 15.13
    DMSO 2315.66
    n-butyl acetate 41.07
    n-octanol 45.45
    chloroform 51.78
    n-propyl acetate 53.99
    acetic acid 1053.17
    dichloromethane 109.97
    cyclohexanone 188.02
    propylene glycol 418.66
    isopropyl acetate 35.62
    DMAc 940.19
    2-ethoxyethanol 459.14
    isopentanol 169.86
    n-heptane 5.94
    ethyl formate 191.18
    1,2-dichloroethane 88.53
    n-hexanol 68.09
    2-methoxyethanol 926.91
    isobutyl acetate 26.3
    tetrachloromethane 11.69
    n-pentyl acetate 30.18
    transcutol 464.05
    n-heptanol 40.6
    ethylbenzene 13.18
    MIBK 49.25
    2-propoxyethanol 177.48
    tert-butanol 400.14
    MTBE 99.05
    2-butoxyethanol 119.07
    propionic acid 317.79
    o-xylene 22.71
    formic acid 1672.01
    diethyl ether 58.09
    m-xylene 14.43
    p-xylene 21.43
    chlorobenzene 22.67
    dimethyl carbonate 57.29
    n-octane 3.01
    formamide 1569.09
    cyclopentanone 247.73
    2-pentanone 80.78
    anisole 57.48
    cyclopentyl methyl ether 77.5
    gamma-butyrolactone 327.07
    1-methoxy-2-propanol 382.26
    pyridine 126.62
    3-pentanone 50.49
    furfural 393.78
    n-dodecane 2.65
    diethylene glycol 303.49
    diisopropyl ether 15.36
    tert-amyl alcohol 257.47
    acetylacetone 106.96
    n-hexadecane 2.83
    acetophenone 73.09
    methyl propionate 76.68
    isopentyl acetate 38.02
    trichloroethylene 109.08
    n-nonanol 37.4
    cyclohexanol 147.69
    benzyl alcohol 96.13
    2-ethylhexanol 37.86
    isooctanol 33.56
    dipropyl ether 30.74
    1,2-dichlorobenzene 28.0
    ethyl lactate 68.52
    propylene carbonate 141.73
    n-methylformamide 841.4
    2-pentanol 101.6
    n-pentane 6.89
    1-propoxy-2-propanol 105.76
    1-methoxy-2-propyl acetate 52.93
    2-(2-methoxypropoxy) propanol 120.8
    mesitylene 13.3
    ε-caprolactone 171.73
    p-cymene 13.21
    epichlorohydrin 261.57
    1,1,1-trichloroethane 27.77
    2-aminoethanol 687.47
    morpholine-4-carbaldehyde 619.87
    sulfolane 575.58
    2,2,4-trimethylpentane 5.48
    2-methyltetrahydrofuran 169.47
    n-hexyl acetate 46.09
    isooctane 2.85
    2-(2-butoxyethoxy)ethanol 158.15
    sec-butyl acetate 25.82
    tert-butyl acetate 45.32
    decalin 5.79
    glycerin 633.54
    diglyme 321.46
    acrylic acid 372.05
    isopropyl myristate 18.91
    n-butyric acid 263.99
    acetyl acetate 50.04
    di(2-ethylhexyl) phthalate 36.32
    ethyl propionate 40.31
    nitromethane 1005.54
    1,2-diethoxyethane 69.37
    benzonitrile 76.62
    trioctyl phosphate 27.04
    1-bromopropane 30.4
    gamma-valerolactone 409.15
    n-decanol 27.85
    triethyl phosphate 31.07
    4-methyl-2-pentanol 48.02
    propionitrile 100.05
    vinylene carbonate 155.82
    1,1,2-trichlorotrifluoroethane 333.28
    DMS 43.29
    cumene 12.97
    2-octanol 24.32
    2-hexanone 54.69
    octyl acetate 27.92
    limonene 21.21
    1,2-dimethoxyethane 504.77
    ethyl orthosilicate 28.8
    tributyl phosphate 31.12
    diacetone alcohol 128.35
    N,N-dimethylaniline 59.12
    acrylonitrile 176.65
    aniline 62.94
    1,3-propanediol 643.1
    bromobenzene 15.24
    dibromomethane 51.61
    1,1,2,2-tetrachloroethane 95.0
    2-methyl-cyclohexyl acetate 37.89
    tetrabutyl urea 52.1
    diisobutyl methanol 25.12
    2-phenylethanol 51.74
    styrene 17.07
    dioctyl adipate 44.4
    dimethyl sulfate 153.83
    ethyl butyrate 39.12
    methyl lactate 122.79
    butyl lactate 54.43
    diethyl carbonate 30.12
    propanediol butyl ether 152.23
    triethyl orthoformate 35.34
    p-tert-butyltoluene 12.56
    methyl 4-tert-butylbenzoate 70.61
    morpholine 446.6
    tert-butylamine 162.21
    n-dodecanol 21.54
    dimethoxymethane 303.49
    ethylene carbonate 120.68
    cyrene 157.28
    2-ethoxyethyl acetate 49.83
    2-ethylhexyl acetate 25.95
    1,2,4-trichlorobenzene 38.18
    4-methylpyridine 109.95
    dibutyl ether 27.28
    2,6-dimethyl-4-heptanol 25.12
    DEF 259.83
    dimethyl isosorbide 144.14
    tetrachloroethylene 74.57
    eugenol 83.49
    triacetin 72.34
    span 80 95.26
    1,4-butanediol 305.78
    1,1-dichloroethane 38.05
    2-methyl-1-pentanol 111.1
    methyl formate 529.76
    2-methyl-1-butanol 169.48
    n-decane 3.71
    butyronitrile 112.62
    3,7-dimethyl-1-octanol 41.95
    1-chlorooctane 12.7
    1-chlorotetradecane 5.98
    n-nonane 3.66
    undecane 3.04
    tert-butylcyclohexane 4.65
    cyclooctane 5.23
    cyclopentanol 220.06
    tetrahydropyran 143.73
    tert-amyl methyl ether 74.45
    2,5,8-trioxanonane 224.51
    1-hexene 14.01
    2-isopropoxyethanol 189.39
    2,2,2-trifluoroethanol 366.23
    methyl butyrate 88.34

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction