Glucamine

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  • Identifiers

    CAS number
    488-43-7

    Molecular formula
    C6H15NO5

    SMILES
    C([C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)N

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 71.39%
    Sweet 46.38%
    Fishy 25.64%
    Alcoholic 21.39%
    Cooling 18.54%
    Savory 17.41%
    Bitter 15.86%
    Clean 14.7%
    Oily 14.61%
    Buttery 13.39%

     

    Flavor
    Odorless 73.49%
    Sweet 54.29%
    Sweet-like 33.02%
    Bland 22.4%
    Mild 22.15%
    Very slight 22.03%
    Very mild 21.57%
    Bitter 19.84%
    Cauliflower 19.24%
    Soup 19.14%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -3.4

    pKa est.
    5.36 (weak acid)

    Molecular weight
    181.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    686°C

    Flash point

    • 229.65 ˚C est.

  • Synonyms

    • 488-43-7
    • GLUCAMINE
    • 1-Amino-1-deoxy-D-glucitol
    • 5QN16UUF80
    • DTXSID901032334
    • RefChem:663086
    • GlyTouCan:G24280RP
    • DTXCID101517338
    • G24280RP
    • 207-677-3
    • D-Glucamine
    • (2R,3R,4R,5S)-6-Aminohexane-1,2,3,4,5-pentaol
    • (2R,3R,4R,5S)-6-aminohexane-1,2,3,4,5-pentol
    • 1-Amino-1-deoxy-D-sorbitol
    • 1-Amino-1-deoxysorbitol
    • 1-amino-1-deoxyglucitol
    • D-Glucamine (>75%)
    • MFCD00077776
    • Glycamine
    • C6H15NO5
    • D-Glucitol, 1-amino-1-deoxy-
    • UNII-5QN16UUF80
    • D-glucamin
    • D-Glucoamine
    • EINECS 207-677-3
    • 1-amino-desoxysorbitol
    • D-Glucamine, 98%
    • GLUCAMINE [MI]
    • 1-amino-1-deoxy-glucitol
    • EC 207-677-3
    • SCHEMBL2361
    • 1-Amino-1-deoxy-glucosamine
    • 1-Amino-1-deoxy-L-sorbitol
    • D-Glucamine (>75per cent)
    • 1-amino-1-desoxy-D-glucitol
    • orb2941981
    • SDOFMBGMRVAJNF-SLPGGIOYSA-
    • CHEBI:231253
    • 1-Amino-1-deoxy-D-sorbitol, 98%
    • AKOS016010317
    • HY-W016445
    • MG06629
    • SY075846
    • G0252
    • NS00100246
    • D90737
    • F046819
    • Q27262753
    • InChI=1/C6H15NO5/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,8-12H,1-2,7H2/t3-,4+,5+,6+/m0/s1
    • 488-43-7

  • Applications

    Glucamine (CAS 488-43-7) is a versatile amino sugar derivative that serves as a building block in chemical synthesis. In industrial manufacturing, it is commonly evaluated as an intermediate for pharmaceutical and agrochemical compounds. It can function as a functional monomer or crosslinking/functionalization agent in polymers and specialty resins. In coatings and inks, glucamine may act as a chelating agent or stabilizer, aiding pigment dispersion and formulation stability. In cosmetics and personal care, it is sometimes used as a formulation aid or textural/compatibility-enhancing additive. In cleaning formulations, it may participate as a chelating or stabilizing component that improves detergent performance and reduces metal-catalyzed degradation. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.21
    methanol 1.67
    isopropanol 0.09
    water 791.6
    ethyl acetate 0.11
    n-propanol 0.16
    acetone 0.09
    n-butanol 0.11
    acetonitrile 0.14
    DMF 11.05
    toluene 0.03
    isobutanol 0.1
    1,4-dioxane 0.51
    methyl acetate 0.08
    THF 0.24
    2-butanone 0.09
    n-pentanol 0.06
    sec-butanol 0.13
    n-hexane 0.02
    ethylene glycol 26.89
    NMP 24.46
    cyclohexane 0.15
    DMSO 48.19
    n-butyl acetate 0.08
    n-octanol 0.1
    chloroform 0.03
    n-propyl acetate 0.05
    acetic acid 2.98
    dichloromethane 0.04
    cyclohexanone 0.46
    propylene glycol 6.17
    isopropyl acetate 0.07
    DMAc 8.6
    2-ethoxyethanol 1.28
    isopentanol 0.08
    n-heptane 0.12
    ethyl formate 0.12
    1,2-dichloroethane 0.06
    n-hexanol 0.18
    2-methoxyethanol 4.1
    isobutyl acetate 0.02
    tetrachloromethane 0.05
    n-pentyl acetate 0.06
    transcutol 1.47
    n-heptanol 0.19
    ethylbenzene 0.03
    MIBK 0.07
    2-propoxyethanol 1.21
    tert-butanol 0.13
    MTBE 0.04
    2-butoxyethanol 0.78
    propionic acid 0.88
    o-xylene 0.09
    formic acid 116.67
    diethyl ether 0.06
    m-xylene 0.06
    p-xylene 0.04
    chlorobenzene 0.02
    dimethyl carbonate 0.5
    n-octane 0.04
    formamide 38.39
    cyclopentanone 0.54
    2-pentanone 0.1
    anisole 0.05
    cyclopentyl methyl ether 0.28
    gamma-butyrolactone 0.93
    1-methoxy-2-propanol 1.92
    pyridine 0.19
    3-pentanone 0.16
    furfural 1.53
    n-dodecane 0.02
    diethylene glycol 7.73
    diisopropyl ether 0.04
    tert-amyl alcohol 0.19
    acetylacetone 0.27
    n-hexadecane 0.02
    acetophenone 0.14
    methyl propionate 0.31
    isopentyl acetate 0.06
    trichloroethylene 0.07
    n-nonanol 0.1
    cyclohexanol 0.46
    benzyl alcohol 0.18
    2-ethylhexanol 0.14
    isooctanol 0.14
    dipropyl ether 0.15
    1,2-dichlorobenzene 0.03
    ethyl lactate 0.46
    propylene carbonate 0.36
    n-methylformamide 4.21
    2-pentanol 0.09
    n-pentane 0.03
    1-propoxy-2-propanol 0.81
    1-methoxy-2-propyl acetate 0.37
    2-(2-methoxypropoxy) propanol 0.69
    mesitylene 0.07
    ε-caprolactone 0.58
    p-cymene 0.09
    epichlorohydrin 0.21
    1,1,1-trichloroethane 0.02
    2-aminoethanol 7.66
    morpholine-4-carbaldehyde 11.04
    sulfolane 11.5
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 0.17
    n-hexyl acetate 0.07
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 0.91
    sec-butyl acetate 0.03
    tert-butyl acetate 0.1
    decalin 0.04
    glycerin 55.01
    diglyme 1.63
    acrylic acid 2.33
    isopropyl myristate 0.03
    n-butyric acid 0.47
    acetyl acetate 0.13
    di(2-ethylhexyl) phthalate 0.1
    ethyl propionate 0.09
    nitromethane 2.19
    1,2-diethoxyethane 0.11
    benzonitrile 0.07
    trioctyl phosphate 0.1
    1-bromopropane 0.02
    gamma-valerolactone 1.82
    n-decanol 0.08
    triethyl phosphate 0.2
    4-methyl-2-pentanol 0.07
    propionitrile 0.07
    vinylene carbonate 0.36
    1,1,2-trichlorotrifluoroethane 4.6
    DMS 0.18
    cumene 0.04
    2-octanol 0.1
    2-hexanone 0.04
    octyl acetate 0.05
    limonene 0.15
    1,2-dimethoxyethane 0.54
    ethyl orthosilicate 0.18
    tributyl phosphate 0.08
    diacetone alcohol 0.64
    N,N-dimethylaniline 0.15
    acrylonitrile 0.18
    aniline 0.12
    1,3-propanediol 3.01
    bromobenzene 0.01
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.11
    2-methyl-cyclohexyl acetate 0.11
    tetrabutyl urea 0.19
    diisobutyl methanol 0.13
    2-phenylethanol 0.21
    styrene 0.02
    dioctyl adipate 0.07
    dimethyl sulfate 2.76
    ethyl butyrate 0.11
    methyl lactate 2.41
    butyl lactate 0.28
    diethyl carbonate 0.07
    propanediol butyl ether 1.13
    triethyl orthoformate 0.17
    p-tert-butyltoluene 0.09
    methyl 4-tert-butylbenzoate 0.37
    morpholine 0.85
    tert-butylamine 0.06
    n-dodecanol 0.06
    dimethoxymethane 0.94
    ethylene carbonate 0.27
    cyrene 3.21
    2-ethoxyethyl acetate 0.11
    2-ethylhexyl acetate 0.06
    1,2,4-trichlorobenzene 0.05
    4-methylpyridine 0.1
    dibutyl ether 0.05
    2,6-dimethyl-4-heptanol 0.13
    DEF 1.15
    dimethyl isosorbide 1.39
    tetrachloroethylene 0.17
    eugenol 0.5
    triacetin 0.23
    span 80 0.88
    1,4-butanediol 1.35
    1,1-dichloroethane 0.01
    2-methyl-1-pentanol 0.06
    methyl formate 1.34
    2-methyl-1-butanol 0.12
    n-decane 0.03
    butyronitrile 0.05
    3,7-dimethyl-1-octanol 0.07
    1-chlorooctane 0.03
    1-chlorotetradecane 0.02
    n-nonane 0.03
    undecane 0.02
    tert-butylcyclohexane 0.02
    cyclooctane 0.1
    cyclopentanol 0.53
    tetrahydropyran 0.16
    tert-amyl methyl ether 0.09
    2,5,8-trioxanonane 1.58
    1-hexene 0.02
    2-isopropoxyethanol 0.46
    2,2,2-trifluoroethanol 6.86
    methyl butyrate 0.11

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction