Glechomafuran

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  • Identifiers

    CAS number
    38146-67-7

    Molecular formula
    C15H20O3

    SMILES
    CC1=COC2=C1CC3C(O3)(CCC4C(C2)(O4)C)C

    Safety labels

  • Odor profile

    Fragrance
    Earthy 39.92%
    Green 36.82%
    Fresh 36.76%
    Woody 35.84%
    Herbal 31.6%
    Sweet 31.55%
    Mint 30.58%
    Floral 29.79%
    Musty 25.51%
    Citrus 23.8%

     

    Flavor
    Earthy 45.85%
    Roasted 33.68%
    Green 33.09%
    Nutty 31.36%
    Musty 29.82%
    Earth 29.32%
    Bitter 27.39%
    Potato 26.58%
    Vegetable 26.33%
    Coffee 24.41%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    5.07 (weak acid)

    Molecular weight
    248.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    380°C

    Melting point expt.

    • 115 °C

    Flash point

    • 133.8 ˚C est.

  • Synonyms

    • GLECHOMAFURAN
    • 38146-67-7
    • NSC 380468
    • Bisoxireno(4,5:8,9)cyclodeca(1,2-b)furan, 1a,2,6,6a,7a,8,9,9a-octahydro-1a,5,7a-trimethyl-, (1aR-(1aR*,6aR*,7aR*,9aR*))-
    • 5,10,15-trimethyl-4,9,13-trioxatetracyclo[10.3.0.03,5.08,10]pentadeca-1(12),14-diene
    • 5,10,15-trimethyl-4,9,13-trioxatetracyclo[10.3.0.0^{3,5}.0^{8,10}]pentadeca-1(12),14-diene
    • 5,10,15-trimethyl-4,9,13-trioxatetracyclo(10.3.0.03,5.08,10)pentadeca-1(12),14-diene
    • 5,10,15-trimethyl-4,9,13-trioxatetracyclo(10.3.0.0^(3,5).0^(8,10))pentadeca-1(12),14-diene
    • RefChem:143322
    • FNQFNSGVMLMZNV-LXTVHRRPSA-N
    • NSC380468
    • Alexandrofuran
    • CHEMBL1999338
    • SCHEMBL29934821
    • DTXSID50959079
    • CHEBI:231295
    • NSC-380468
    • NCGC00385934-01
    • NCI60_003596
    • 1a,5,7a-Trimethyl-1a,2,6,6a,7a,8,9,9a-octahydrobisoxireno[4,5:8,9]cyclodeca[1,2-b]furan
    • 38146-67-7

  • Applications

    Glechomafuran (CAS 38146-67-7) may be used as an intermediate and processing aid in organic synthesis across several industries. In fragrance and flavor development, it can serve as a precursor for aroma compounds or as a component in fragrance formulations; in cosmetics and personal care, it is evaluated as a potential fragrance ingredient or fixative; in coatings and inks, it may function as a co-solvent or reactive diluent to adjust viscosity and drying characteristics; in polymers and plastics, it can act as a monomer modifier or processing aid; and in pharmaceutical or agrochemical research, it is often used as a synthetic building block for more complex molecules.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 80.53
    methanol 122.63
    isopropanol 58.91
    water 2.17
    ethyl acetate 85.64
    n-propanol 70.4
    acetone 110.42
    n-butanol 64.57
    acetonitrile 105.59
    DMF 118.24
    toluene 102.8
    isobutanol 55.0
    1,4-dioxane 273.59
    methyl acetate 112.43
    THF 235.76
    2-butanone 112.31
    n-pentanol 60.77
    sec-butanol 42.71
    n-hexane 2.35
    ethylene glycol 40.59
    NMP 85.79
    cyclohexane 10.55
    DMSO 127.19
    n-butyl acetate 74.23
    n-octanol 39.85
    chloroform 395.18
    n-propyl acetate 81.14
    acetic acid 86.55
    dichloromethane 305.74
    cyclohexanone 143.79
    propylene glycol 43.0
    isopropyl acetate 60.86
    DMAc 165.72
    2-ethoxyethanol 143.55
    isopentanol 60.75
    n-heptane 3.6
    ethyl formate 86.67
    1,2-dichloroethane 121.35
    n-hexanol 58.04
    2-methoxyethanol 172.18
    isobutyl acetate 72.89
    tetrachloromethane 35.64
    n-pentyl acetate 56.75
    transcutol 317.33
    n-heptanol 40.43
    ethylbenzene 53.52
    MIBK 59.91
    2-propoxyethanol 153.42
    tert-butanol 57.05
    MTBE 45.64
    2-butoxyethanol 97.84
    propionic acid 64.85
    o-xylene 53.86
    formic acid 54.54
    diethyl ether 51.82
    m-xylene 53.95
    p-xylene 78.22
    chlorobenzene 110.94
    dimethyl carbonate 55.19
    n-octane 2.37
    formamide 86.25
    cyclopentanone 150.62
    2-pentanone 76.0
    anisole 118.75
    cyclopentyl methyl ether 74.42
    gamma-butyrolactone 142.01
    1-methoxy-2-propanol 113.55
    pyridine 244.7
    3-pentanone 64.73
    furfural 187.95
    n-dodecane 3.37
    diethylene glycol 145.18
    diisopropyl ether 17.64
    tert-amyl alcohol 37.2
    acetylacetone 99.52
    n-hexadecane 4.01
    acetophenone 115.64
    methyl propionate 75.72
    isopentyl acetate 79.8
    trichloroethylene 270.49
    n-nonanol 41.67
    cyclohexanol 56.82
    benzyl alcohol 118.78
    2-ethylhexanol 39.45
    isooctanol 34.91
    dipropyl ether 36.59
    1,2-dichlorobenzene 90.65
    ethyl lactate 50.55
    propylene carbonate 93.49
    n-methylformamide 84.96
    2-pentanol 33.18
    n-pentane 2.95
    1-propoxy-2-propanol 89.49
    1-methoxy-2-propyl acetate 97.8
    2-(2-methoxypropoxy) propanol 103.61
    mesitylene 29.37
    ε-caprolactone 121.67
    p-cymene 29.87
    epichlorohydrin 192.56
    1,1,1-trichloroethane 103.13
    2-aminoethanol 63.08
    morpholine-4-carbaldehyde 187.3
    sulfolane 109.97
    2,2,4-trimethylpentane 2.78
    2-methyltetrahydrofuran 121.61
    n-hexyl acetate 74.59
    isooctane 2.31
    2-(2-butoxyethoxy)ethanol 137.3
    sec-butyl acetate 59.76
    tert-butyl acetate 52.86
    decalin 7.1
    glycerin 58.76
    diglyme 241.0
    acrylic acid 68.53
    isopropyl myristate 37.53
    n-butyric acid 77.31
    acetyl acetate 74.73
    di(2-ethylhexyl) phthalate 50.62
    ethyl propionate 63.61
    nitromethane 140.78
    1,2-diethoxyethane 106.9
    benzonitrile 137.57
    trioctyl phosphate 31.39
    1-bromopropane 58.5
    gamma-valerolactone 230.89
    n-decanol 31.96
    triethyl phosphate 40.01
    4-methyl-2-pentanol 28.79
    propionitrile 94.2
    vinylene carbonate 122.28
    1,1,2-trichlorotrifluoroethane 142.74
    DMS 79.65
    cumene 36.17
    2-octanol 25.73
    2-hexanone 79.36
    octyl acetate 45.22
    limonene 30.5
    1,2-dimethoxyethane 237.45
    ethyl orthosilicate 39.8
    tributyl phosphate 37.03
    diacetone alcohol 62.99
    N,N-dimethylaniline 75.58
    acrylonitrile 120.86
    aniline 107.63
    1,3-propanediol 86.45
    bromobenzene 115.34
    dibromomethane 162.3
    1,1,2,2-tetrachloroethane 201.32
    2-methyl-cyclohexyl acetate 69.57
    tetrabutyl urea 48.92
    diisobutyl methanol 24.19
    2-phenylethanol 108.53
    styrene 66.55
    dioctyl adipate 56.75
    dimethyl sulfate 57.11
    ethyl butyrate 61.66
    methyl lactate 51.33
    butyl lactate 54.61
    diethyl carbonate 54.52
    propanediol butyl ether 85.91
    triethyl orthoformate 54.04
    p-tert-butyltoluene 26.16
    methyl 4-tert-butylbenzoate 70.81
    morpholine 234.64
    tert-butylamine 30.67
    n-dodecanol 25.04
    dimethoxymethane 134.56
    ethylene carbonate 104.02
    cyrene 102.97
    2-ethoxyethyl acetate 100.08
    2-ethylhexyl acetate 65.88
    1,2,4-trichlorobenzene 116.62
    4-methylpyridine 188.88
    dibutyl ether 39.82
    2,6-dimethyl-4-heptanol 24.19
    DEF 75.78
    dimethyl isosorbide 140.35
    tetrachloroethylene 121.56
    eugenol 85.29
    triacetin 91.09
    span 80 78.19
    1,4-butanediol 56.01
    1,1-dichloroethane 108.63
    2-methyl-1-pentanol 57.12
    methyl formate 75.51
    2-methyl-1-butanol 49.78
    n-decane 5.06
    butyronitrile 81.81
    3,7-dimethyl-1-octanol 42.41
    1-chlorooctane 22.18
    1-chlorotetradecane 11.42
    n-nonane 3.88
    undecane 4.0
    tert-butylcyclohexane 5.4
    cyclooctane 3.91
    cyclopentanol 58.88
    tetrahydropyran 153.32
    tert-amyl methyl ether 33.19
    2,5,8-trioxanonane 178.33
    1-hexene 14.83
    2-isopropoxyethanol 97.91
    2,2,2-trifluoroethanol 44.55
    methyl butyrate 84.09

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction