Ginsenoside Rg6

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  • Identifiers

    CAS number
    147419-93-0

    Molecular formula
    C42H70O12

    SMILES
    C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2O[C@H]3C[C@@]4([C@H](C[C@H]([C@H]5[C@]4(CC[C@@H]5C(=C)CCC=C(C)C)C)O)[C@@]6([C@@H]3C([C@H](CC6)O)(C)C)C)C)CO)O)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Woody 49.38%
    Odorless 43.0%
    Spicy 38.39%
    Sweet 33.15%
    Balsamic 27.29%
    Mint 27.24%
    Amber 27.03%
    Cooling 25.45%
    Sandalwood 25.1%
    Dry 24.58%

     

    Flavor
    Bitter 50.96%
    Herbal 26.05%
    Fatty 24.18%
    Odorless 24.07%
    Sweet 24.05%
    Sweet-like 23.23%
    Minty 22.93%
    Cedarleaf 22.67%
    Fresh 21.58%
    Mentholic 21.24%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.6

    pKa est.
    4.58 (weak acid)

    Molecular weight
    767.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    1091°C

    Flash point

    • 222.14 ˚C est.

  • Synonyms

    • Ginsenoside Rg6
    • 147419-93-0
    • (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-(6-methylhepta-1,5-dien-2-yl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
    • DTXSID001316941
    • (2S,3R,4R,5R,6S)-2-((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-(6-methylhepta-1,5-dien-2-yl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-6-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl)oxy-6-methyloxane-3,4,5-triol
    • RefChem:143226
    • DTXCID601746762
    • MFCD25371996
    • orb1684960
    • CHEMBL4208939
    • SCHEMBL23960301
    • CHEBI:176312
    • HY-N0907
    • AKOS037514880
    • CS-3849
    • EBC-618465
    • OG31926
    • (2S,3R,4R,5R,6S)-2-{[(2R,3R,4S,5S,6R)-2-{[(1S,3aR,3bR,5S,5aR,7S,9aR,9bR,11R,11aR)-7,11-dihydroxy-3a,3b,6,6,9a-pentamethyl-1-(6-methylhepta-1,5-dien-2-yl)-hexadecahydro-1H-cyclopenta[a]phenanthren-5-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy}-6-methyloxane-3,4,5-triol
    • DA-53559
    • MS-31385
    • (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-(5-methyl-1-methylene-hex-4-enyl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-3-yl]oxy-6-methyl-tetrahydropyran-3,4,5-triol
    • 3beta,12beta-Dihydroxydammara-20,24-dien-6alpha-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
    • 147419-93-0

  • Applications

    Ginsenoside Rg6 (CAS 147419-93-0) is a dammarane-type saponin derived from Panax ginseng that is used in several real-world applications across cosmetics, pharmaceuticals, nutraceuticals, and analytical chemistry. In cosmetics and personal care, it is explored as an active component in ginseng-based skin care formulations. In pharmaceutical research, Rg6 is evaluated as a bioactive saponin and is used in early-stage studies and in vitro assays to understand mechanisms of action. In nutraceuticals, it may be included as part of ginseng-derived extracts or dietary supplement ingredients, subject to regulatory limits. In analytical chemistry and quality control of ginseng products, Rg6 serves as a reference standard for quantifying ginsenosides by LC-MS or related methods. These applications reflect its role as a natural product constituent rather than a standalone formulated additive; usage depends on regulatory status and formulation considerations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.72
    methanol 31.74
    isopropanol 1.41
    water 0.07
    ethyl acetate 2.72
    n-propanol 2.98
    acetone 5.85
    n-butanol 1.39
    acetonitrile 1.5
    DMF 43.14
    toluene 0.71
    isobutanol 1.17
    1,4-dioxane 11.58
    methyl acetate 3.12
    THF 24.57
    2-butanone 3.74
    n-pentanol 1.15
    sec-butanol 0.88
    n-hexane 0.03
    ethylene glycol 5.08
    NMP 43.57
    cyclohexane 0.05
    DMSO 54.34
    n-butyl acetate 1.45
    n-octanol 1.16
    chloroform 6.69
    n-propyl acetate 1.43
    acetic acid 37.61
    dichloromethane 5.86
    cyclohexanone 5.59
    propylene glycol 5.6
    isopropyl acetate 1.69
    DMAc 33.17
    2-ethoxyethanol 13.66
    isopentanol 0.83
    n-heptane 0.05
    ethyl formate 3.67
    1,2-dichloroethane 2.52
    n-hexanol 1.04
    2-methoxyethanol 31.36
    isobutyl acetate 0.89
    tetrachloromethane 0.72
    n-pentyl acetate 2.91
    transcutol 22.25
    n-heptanol 1.55
    ethylbenzene 0.3
    MIBK 1.57
    2-propoxyethanol 15.66
    tert-butanol 1.01
    MTBE 0.78
    2-butoxyethanol 10.86
    propionic acid 5.1
    o-xylene 0.46
    formic acid 35.44
    diethyl ether 1.33
    m-xylene 0.49
    p-xylene 0.34
    chlorobenzene 0.99
    dimethyl carbonate 5.82
    n-octane 0.03
    formamide 22.94
    cyclopentanone 13.56
    2-pentanone 2.66
    anisole 1.79
    cyclopentyl methyl ether 3.22
    gamma-butyrolactone 18.86
    1-methoxy-2-propanol 14.93
    pyridine 6.9
    3-pentanone 2.06
    furfural 22.23
    n-dodecane 0.02
    diethylene glycol 16.97
    diisopropyl ether 0.25
    tert-amyl alcohol 0.83
    acetylacetone 7.74
    n-hexadecane 0.02
    acetophenone 2.71
    methyl propionate 4.03
    isopentyl acetate 1.41
    trichloroethylene 8.95
    n-nonanol 1.22
    cyclohexanol 0.85
    benzyl alcohol 2.67
    2-ethylhexanol 0.5
    isooctanol 1.05
    dipropyl ether 0.98
    1,2-dichlorobenzene 1.08
    ethyl lactate 2.69
    propylene carbonate 6.57
    n-methylformamide 20.74
    2-pentanol 0.55
    n-pentane 0.04
    1-propoxy-2-propanol 6.54
    1-methoxy-2-propyl acetate 5.81
    2-(2-methoxypropoxy) propanol 6.91
    mesitylene 0.26
    ε-caprolactone 6.88
    p-cymene 0.3
    epichlorohydrin 19.41
    1,1,1-trichloroethane 1.43
    2-aminoethanol 8.75
    morpholine-4-carbaldehyde 45.55
    sulfolane 41.62
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 3.96
    n-hexyl acetate 2.84
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 10.43
    sec-butyl acetate 0.81
    tert-butyl acetate 1.94
    decalin 0.03
    glycerin 17.08
    diglyme 21.49
    acrylic acid 10.18
    isopropyl myristate 0.58
    n-butyric acid 5.34
    acetyl acetate 3.57
    di(2-ethylhexyl) phthalate 1.63
    ethyl propionate 1.41
    nitromethane 37.86
    1,2-diethoxyethane 3.07
    benzonitrile 1.52
    trioctyl phosphate 1.02
    1-bromopropane 0.64
    gamma-valerolactone 45.69
    n-decanol 0.61
    triethyl phosphate 1.08
    4-methyl-2-pentanol 0.41
    propionitrile 1.13
    vinylene carbonate 8.32
    1,1,2-trichlorotrifluoroethane 35.37
    DMS 3.27
    cumene 0.22
    2-octanol 0.68
    2-hexanone 1.48
    octyl acetate 1.17
    limonene 0.38
    1,2-dimethoxyethane 13.45
    ethyl orthosilicate 0.99
    tributyl phosphate 0.83
    diacetone alcohol 5.13
    N,N-dimethylaniline 1.34
    acrylonitrile 2.78
    aniline 1.61
    1,3-propanediol 8.55
    bromobenzene 0.85
    dibromomethane 2.34
    1,1,2,2-tetrachloroethane 5.6
    2-methyl-cyclohexyl acetate 1.48
    tetrabutyl urea 1.39
    diisobutyl methanol 0.29
    2-phenylethanol 2.65
    styrene 0.36
    dioctyl adipate 1.59
    dimethyl sulfate 14.89
    ethyl butyrate 1.26
    methyl lactate 9.25
    butyl lactate 4.14
    diethyl carbonate 0.88
    propanediol butyl ether 10.31
    triethyl orthoformate 1.51
    p-tert-butyltoluene 0.31
    methyl 4-tert-butylbenzoate 5.4
    morpholine 13.81
    tert-butylamine 0.27
    n-dodecanol 0.32
    dimethoxymethane 23.93
    ethylene carbonate 5.0
    cyrene 13.62
    2-ethoxyethyl acetate 7.64
    2-ethylhexyl acetate 0.99
    1,2,4-trichlorobenzene 1.96
    4-methylpyridine 3.36
    dibutyl ether 0.51
    2,6-dimethyl-4-heptanol 0.29
    DEF 5.29
    dimethyl isosorbide 12.56
    tetrachloroethylene 4.41
    eugenol 6.03
    triacetin 6.78
    span 80 6.61
    1,4-butanediol 2.99
    1,1-dichloroethane 1.33
    2-methyl-1-pentanol 0.72
    methyl formate 16.61
    2-methyl-1-butanol 0.89
    n-decane 0.04
    butyronitrile 0.88
    3,7-dimethyl-1-octanol 0.67
    1-chlorooctane 0.3
    1-chlorotetradecane 0.07
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.03
    cyclooctane 0.03
    cyclopentanol 1.84
    tetrahydropyran 3.04
    tert-amyl methyl ether 0.76
    2,5,8-trioxanonane 12.57
    1-hexene 0.12
    2-isopropoxyethanol 5.36
    2,2,2-trifluoroethanol 12.37
    methyl butyrate 1.95

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction