Ginsenoside Rc

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  • Identifiers

    CAS number
    11021-14-0

    Molecular formula
    C53H90O22

    SMILES
    CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)C)O)C)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO[C@H]8[C@@H]([C@H]([C@@H](O8)CO)O)O)O)O)O)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 53.52%
    Sweet 37.98%
    Woody 37.7%
    Cooling 26.99%
    Spicy 26.73%
    Mint 26.12%
    Amber 23.75%
    Balsamic 23.69%
    Dry 21.78%
    Warm 21.64%

     

    Flavor
    Bitter 46.05%
    Sweet 39.71%
    Odorless 33.0%
    Fatty 30.68%
    Sweet-like 27.27%
    Bland 22.46%
    Cedarleaf 21.38%
    Mentholic 21.21%
    Patchouli 20.74%
    Old paper 20.64%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.9

    pKa est.
    4.15 (weak acid)

    Molecular weight
    1079.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    3329°C

    Flash point

    • 222.22 ˚C est.

  • Synonyms

    • Ginsenoside Rc
    • 11021-14-0
    • Panaxoside RC
    • ginsenoside-Rc
    • NSC 310104
    • 0K83B0L786
    • CHEBI:77154
    • DTXSID60911542
    • NSC-310104
    • RefChem:37153
    • DTXCID401776183
    • beta-D-Glucopyranoside, (3beta,12beta)-20-((6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-
    • 234-253-5
    • (2S,3R,4S,5S,6R)-2-((2R,3R,4S,5S,6R)-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-17-((2S)-2-((2S,3R,4S,5S,6R)-6-(((2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)oxymethyl)-3,4,5-trihydroxyoxan-2-yl)oxy-6-methylhept-5-en-2-yl)-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl)oxy-6-(hydroxymethyl)oxane-3,4,5-triol
    • MFCD00133368
    • GinsenosideRc
    • 20-[(6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranosyl)oxy]-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
    • UNII-0K83B0L786
    • 20-((6-O-alpha-L-Arabinofuranosyl-beta-D-glucopyranosyl)oxy)-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
    • EINECS 234-253-5
    • BRN 1677618
    • 20(S)-ginsenoside Rc
    • Ginsenoside Rc (Standard)
    • CHEMBL451702
    • orb1305117
    • SCHEMBL29350639
    • HY-N0042R
    • JDCPEKQWFDWQLI-LUQKBWBOSA-N
    • EX-A6779
    • HY-N0042
    • MSK40134
    • s9266
    • AKOS037514670
    • CCG-270633
    • CS-3837
    • EBC-615843
    • OG09295
    • NCGC00485983-01
    • AC-34659
    • AS-56539
    • NS00066757
    • 021G140
    • Q27146714
    • (3b,12b)-20-[(6-O-a-L-Arabinofuranosyl-b-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-(b-D-glucopyranosyl)-b-D-glucopyranos ide
    • (3beta,12beta)-20-{[6-O-(alpha-L-arabinofuranosyl)-beta-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
    • .BETA.-D-GLUCOPYRANOSIDE, (3.BETA.,12.BETA.)-20-((6-O-.ALPHA.-L-ARABINOFURANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)-12-HYDROXYDAMMAR-24-EN-3-YL 2-O-.BETA.-D-GLUCOPYRANOSYL-
    • 20(S)-protopanaxadiol-3-[O-beta-D-glucopyranosyl(1->2)-beta-D-glucopyranoside]-20-[O-alpha-L-arabinofuranosyl(1->6)-beta-D-glucopyranoside]
    • 20-[alpha-L-arabinofuranosyl-(1->2)-beta-D glucopyranosyloxy]-3beta-[beta-D-glucopyranosyl-(1->2)-beta-D glucopyranosyloxy]dammar-24-en-12beta-ol
    • GINSENOSIDE RC (CONSTITUENT OF AMERICAN GINSENG, ASIAN GINSENG, AND TIENCHI GINSENG) [DSC]
    • 11021-14-0

  • Applications

    Ginsenoside Rc (CAS 11021-14-0) is a triterpenoid saponin with practical applications across several industries, including cosmetics/personal care as a botanical ingredient in skin and hair formulations; pharmaceuticals/biomedical research as a natural product used for study and as a potential lead compound in formulation development; nutraceuticals/dietary supplements as a plant-derived component in extracts or supplement products; and household products/cleaning where it can function as a natural surfactant or emulsifier and contribute to formulation stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.81
    methanol 18.77
    isopropanol 0.53
    water 0.19
    ethyl acetate 2.09
    n-propanol 0.93
    acetone 4.88
    n-butanol 0.39
    acetonitrile 1.93
    DMF 48.48
    toluene 0.46
    isobutanol 0.38
    1,4-dioxane 7.81
    methyl acetate 2.73
    THF 12.84
    2-butanone 2.29
    n-pentanol 0.4
    sec-butanol 0.32
    n-hexane 0.02
    ethylene glycol 4.39
    NMP 44.84
    cyclohexane 0.04
    DMSO 56.97
    n-butyl acetate 0.97
    n-octanol 0.76
    chloroform 4.11
    n-propyl acetate 1.09
    acetic acid 29.79
    dichloromethane 4.2
    cyclohexanone 3.17
    propylene glycol 2.74
    isopropyl acetate 1.27
    DMAc 37.75
    2-ethoxyethanol 7.65
    isopentanol 0.25
    n-heptane 0.04
    ethyl formate 2.53
    1,2-dichloroethane 1.68
    n-hexanol 0.39
    2-methoxyethanol 15.67
    isobutyl acetate 0.59
    tetrachloromethane 0.46
    n-pentyl acetate 2.01
    transcutol 15.15
    n-heptanol 0.86
    ethylbenzene 0.22
    MIBK 0.9
    2-propoxyethanol 7.59
    tert-butanol 0.42
    MTBE 0.45
    2-butoxyethanol 6.46
    propionic acid 3.08
    o-xylene 0.36
    formic acid 43.03
    diethyl ether 0.73
    m-xylene 0.36
    p-xylene 0.3
    chlorobenzene 0.72
    dimethyl carbonate 7.34
    n-octane 0.03
    formamide 29.54
    cyclopentanone 8.34
    2-pentanone 1.53
    anisole 1.33
    cyclopentyl methyl ether 2.04
    gamma-butyrolactone 14.88
    1-methoxy-2-propanol 7.48
    pyridine 4.77
    3-pentanone 1.48
    furfural 19.83
    n-dodecane 0.02
    diethylene glycol 10.87
    diisopropyl ether 0.17
    tert-amyl alcohol 0.34
    acetylacetone 7.32
    n-hexadecane 0.02
    acetophenone 2.35
    methyl propionate 3.46
    isopentyl acetate 0.81
    trichloroethylene 6.77
    n-nonanol 0.79
    cyclohexanol 0.34
    benzyl alcohol 1.54
    2-ethylhexanol 0.24
    isooctanol 0.54
    dipropyl ether 0.72
    1,2-dichlorobenzene 0.92
    ethyl lactate 2.26
    propylene carbonate 5.5
    n-methylformamide 18.92
    2-pentanol 0.19
    n-pentane 0.02
    1-propoxy-2-propanol 3.78
    1-methoxy-2-propyl acetate 4.39
    2-(2-methoxypropoxy) propanol 4.97
    mesitylene 0.2
    ε-caprolactone 3.79
    p-cymene 0.24
    epichlorohydrin 11.94
    1,1,1-trichloroethane 1.02
    2-aminoethanol 4.52
    morpholine-4-carbaldehyde 42.48
    sulfolane 37.32
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 1.94
    n-hexyl acetate 2.0
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 7.21
    sec-butyl acetate 0.59
    tert-butyl acetate 1.35
    decalin 0.02
    glycerin 11.23
    diglyme 15.88
    acrylic acid 8.09
    isopropyl myristate 0.48
    n-butyric acid 2.27
    acetyl acetate 3.71
    di(2-ethylhexyl) phthalate 1.14
    ethyl propionate 1.13
    nitromethane 50.82
    1,2-diethoxyethane 2.36
    benzonitrile 1.37
    trioctyl phosphate 0.73
    1-bromopropane 0.34
    gamma-valerolactone 30.47
    n-decanol 0.44
    triethyl phosphate 0.91
    4-methyl-2-pentanol 0.16
    propionitrile 0.91
    vinylene carbonate 7.83
    1,1,2-trichlorotrifluoroethane 28.44
    DMS 3.1
    cumene 0.16
    2-octanol 0.41
    2-hexanone 0.98
    octyl acetate 0.95
    limonene 0.27
    1,2-dimethoxyethane 8.83
    ethyl orthosilicate 0.76
    tributyl phosphate 0.62
    diacetone alcohol 3.15
    N,N-dimethylaniline 1.2
    acrylonitrile 2.86
    aniline 0.91
    1,3-propanediol 2.93
    bromobenzene 0.64
    dibromomethane 1.43
    1,1,2,2-tetrachloroethane 3.91
    2-methyl-cyclohexyl acetate 0.98
    tetrabutyl urea 1.22
    diisobutyl methanol 0.16
    2-phenylethanol 1.52
    styrene 0.27
    dioctyl adipate 1.27
    dimethyl sulfate 18.93
    ethyl butyrate 0.99
    methyl lactate 7.59
    butyl lactate 2.79
    diethyl carbonate 0.74
    propanediol butyl ether 6.77
    triethyl orthoformate 1.21
    p-tert-butyltoluene 0.24
    methyl 4-tert-butylbenzoate 4.35
    morpholine 7.33
    tert-butylamine 0.13
    n-dodecanol 0.25
    dimethoxymethane 19.85
    ethylene carbonate 3.97
    cyrene 10.82
    2-ethoxyethyl acetate 6.05
    2-ethylhexyl acetate 0.64
    1,2,4-trichlorobenzene 1.49
    4-methylpyridine 2.35
    dibutyl ether 0.41
    2,6-dimethyl-4-heptanol 0.16
    DEF 4.25
    dimethyl isosorbide 10.29
    tetrachloroethylene 3.11
    eugenol 4.74
    triacetin 6.34
    span 80 4.49
    1,4-butanediol 1.53
    1,1-dichloroethane 0.9
    2-methyl-1-pentanol 0.25
    methyl formate 18.29
    2-methyl-1-butanol 0.25
    n-decane 0.05
    butyronitrile 0.52
    3,7-dimethyl-1-octanol 0.37
    1-chlorooctane 0.23
    1-chlorotetradecane 0.07
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.02
    cyclooctane 0.02
    cyclopentanol 0.79
    tetrahydropyran 1.52
    tert-amyl methyl ether 0.44
    2,5,8-trioxanonane 9.99
    1-hexene 0.07
    2-isopropoxyethanol 3.19
    2,2,2-trifluoroethanol 13.55
    methyl butyrate 1.37

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction