Ginsenoside Ra2

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  • Identifiers

    CAS number
    83459-42-1

    Molecular formula
    C58H98O26

    SMILES
    CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)C)O)C)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO[C@H]8[C@@H]([C@H]([C@@H](O8)CO)O)O[C@H]9[C@@H]([C@H]([C@@H](CO9)O)O)O)O)O)O)C

    Safety labels

  • Odor profile

    Fragrance
    Odorless 56.24%
    Sweet 38.98%
    Woody 35.04%
    Cooling 26.03%
    Spicy 25.18%
    Mint 24.14%
    Balsamic 22.07%
    Amber 21.61%
    Warm 20.82%
    Dry 20.38%

     

    Flavor
    Bitter 46.79%
    Sweet 41.19%
    Odorless 34.38%
    Fatty 32.46%
    Sweet-like 28.05%
    Bland 23.16%
    Cedarleaf 21.16%
    Mentholic 21.07%
    Metallic 20.78%
    Cauliflower 20.59%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.6

    pKa est.
    4.06 (weak acid)

    Molecular weight
    1211.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    3609°C

    Flash point

    • 194.31 ˚C est.

  • Synonyms

    • Ginsenoside Ra2
    • 83459-42-1
    • RefChem:143219
    • orb1684576
    • SCHEMBL29400806
    • DTXSID901317134
    • HY-N4260
    • MSK185094
    • AKOS040760423
    • DA-63763
    • MS-32052
    • CS-0032559
    • 12beta-Hydroxy-20-{[beta-D-xylopyranosyl-(1->2)-alpha-L-arabinofuranosyl-(1->6)-beta-D-glucopyranosyl]oxy}dammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
    • 83459-42-1

  • Applications

    Ginsenoside Ra2 (CAS 83459-42-1), a saponin component of Panax ginseng, finds use as a bioactive ingredient in cosmetics and personal care formulations, where it may contribute to skin-beneficial properties when included in botanical extracts. It is commonly studied in pharmaceutical and pharmacological research as part of ginseng-derived extracts, serving as a reference compound or active constituent in drug discovery and formulation development. In nutraceutical and functional food contexts, Ra2-containing extracts are evaluated as dietary supplement constituents. Because ginsenosides are natural amphiphilic molecules with surface-active properties, Ra2 may serve as a natural surfactant or emulsifier in cleaning and household products or in formulation processes. Some research explores agricultural applications, including as a plant defense elicitor or biostimulant to support sustainable crop management. Subject to local regulations and formulation limits, Ra2-containing materials may be used within appropriate product categories.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.44
    methanol 16.94
    isopropanol 0.43
    water 0.21
    ethyl acetate 1.75
    n-propanol 0.75
    acetone 3.97
    n-butanol 0.31
    acetonitrile 1.76
    DMF 47.62
    toluene 0.41
    isobutanol 0.3
    1,4-dioxane 6.79
    methyl acetate 2.43
    THF 10.2
    2-butanone 1.94
    n-pentanol 0.32
    sec-butanol 0.26
    n-hexane 0.02
    ethylene glycol 4.03
    NMP 43.58
    cyclohexane 0.03
    DMSO 49.37
    n-butyl acetate 0.82
    n-octanol 0.66
    chloroform 3.38
    n-propyl acetate 0.96
    acetic acid 25.11
    dichloromethane 3.53
    cyclohexanone 2.64
    propylene glycol 2.48
    isopropyl acetate 1.06
    DMAc 36.62
    2-ethoxyethanol 6.63
    isopentanol 0.2
    n-heptane 0.04
    ethyl formate 2.13
    1,2-dichloroethane 1.39
    n-hexanol 0.31
    2-methoxyethanol 13.65
    isobutyl acetate 0.51
    tetrachloromethane 0.36
    n-pentyl acetate 1.77
    transcutol 14.43
    n-heptanol 0.72
    ethylbenzene 0.19
    MIBK 0.74
    2-propoxyethanol 6.58
    tert-butanol 0.34
    MTBE 0.37
    2-butoxyethanol 5.76
    propionic acid 2.63
    o-xylene 0.33
    formic acid 44.61
    diethyl ether 0.6
    m-xylene 0.33
    p-xylene 0.27
    chlorobenzene 0.61
    dimethyl carbonate 7.28
    n-octane 0.03
    formamide 29.51
    cyclopentanone 6.85
    2-pentanone 1.26
    anisole 1.19
    cyclopentyl methyl ether 1.7
    gamma-butyrolactone 13.09
    1-methoxy-2-propanol 6.6
    pyridine 4.28
    3-pentanone 1.27
    furfural 19.05
    n-dodecane 0.02
    diethylene glycol 9.9
    diisopropyl ether 0.14
    tert-amyl alcohol 0.28
    acetylacetone 6.4
    n-hexadecane 0.02
    acetophenone 2.16
    methyl propionate 3.09
    isopentyl acetate 0.67
    trichloroethylene 5.93
    n-nonanol 0.69
    cyclohexanol 0.28
    benzyl alcohol 1.34
    2-ethylhexanol 0.2
    isooctanol 0.45
    dipropyl ether 0.64
    1,2-dichlorobenzene 0.79
    ethyl lactate 2.15
    propylene carbonate 4.78
    n-methylformamide 18.03
    2-pentanol 0.15
    n-pentane 0.02
    1-propoxy-2-propanol 3.39
    1-methoxy-2-propyl acetate 3.98
    2-(2-methoxypropoxy) propanol 4.71
    mesitylene 0.18
    ε-caprolactone 3.19
    p-cymene 0.21
    epichlorohydrin 10.06
    1,1,1-trichloroethane 0.83
    2-aminoethanol 3.86
    morpholine-4-carbaldehyde 41.69
    sulfolane 33.51
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 1.57
    n-hexyl acetate 1.75
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 6.76
    sec-butyl acetate 0.5
    tert-butyl acetate 1.15
    decalin 0.02
    glycerin 10.7
    diglyme 15.23
    acrylic acid 7.31
    isopropyl myristate 0.42
    n-butyric acid 1.83
    acetyl acetate 3.2
    di(2-ethylhexyl) phthalate 1.05
    ethyl propionate 1.0
    nitromethane 48.4
    1,2-diethoxyethane 2.13
    benzonitrile 1.2
    trioctyl phosphate 0.66
    1-bromopropane 0.27
    gamma-valerolactone 26.51
    n-decanol 0.39
    triethyl phosphate 0.85
    4-methyl-2-pentanol 0.12
    propionitrile 0.8
    vinylene carbonate 7.05
    1,1,2-trichlorotrifluoroethane 27.04
    DMS 2.9
    cumene 0.14
    2-octanol 0.35
    2-hexanone 0.81
    octyl acetate 0.86
    limonene 0.24
    1,2-dimethoxyethane 7.96
    ethyl orthosilicate 0.7
    tributyl phosphate 0.56
    diacetone alcohol 2.73
    N,N-dimethylaniline 1.11
    acrylonitrile 2.62
    aniline 0.8
    1,3-propanediol 2.39
    bromobenzene 0.55
    dibromomethane 1.16
    1,1,2,2-tetrachloroethane 3.36
    2-methyl-cyclohexyl acetate 0.86
    tetrabutyl urea 1.14
    diisobutyl methanol 0.14
    2-phenylethanol 1.3
    styrene 0.25
    dioctyl adipate 1.17
    dimethyl sulfate 19.15
    ethyl butyrate 0.87
    methyl lactate 7.23
    butyl lactate 2.56
    diethyl carbonate 0.67
    propanediol butyl ether 6.29
    triethyl orthoformate 1.13
    p-tert-butyltoluene 0.22
    methyl 4-tert-butylbenzoate 4.12
    morpholine 6.36
    tert-butylamine 0.1
    n-dodecanol 0.22
    dimethoxymethane 18.44
    ethylene carbonate 3.47
    cyrene 10.61
    2-ethoxyethyl acetate 5.48
    2-ethylhexyl acetate 0.53
    1,2,4-trichlorobenzene 1.3
    4-methylpyridine 2.05
    dibutyl ether 0.36
    2,6-dimethyl-4-heptanol 0.14
    DEF 3.83
    dimethyl isosorbide 10.17
    tetrachloroethylene 2.63
    eugenol 4.56
    triacetin 6.07
    span 80 4.3
    1,4-butanediol 1.31
    1,1-dichloroethane 0.73
    2-methyl-1-pentanol 0.2
    methyl formate 17.56
    2-methyl-1-butanol 0.2
    n-decane 0.04
    butyronitrile 0.43
    3,7-dimethyl-1-octanol 0.32
    1-chlorooctane 0.2
    1-chlorotetradecane 0.06
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.02
    cyclooctane 0.02
    cyclopentanol 0.65
    tetrahydropyran 1.24
    tert-amyl methyl ether 0.38
    2,5,8-trioxanonane 9.65
    1-hexene 0.06
    2-isopropoxyethanol 2.79
    2,2,2-trifluoroethanol 12.33
    methyl butyrate 1.19

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction