Ginsenoside F2

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  • Identifiers

    CAS number
    62025-49-4

    Molecular formula
    C42H72O13

    SMILES
    CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)C)O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 54.42%
    Odorless 39.34%
    Sweet 39.16%
    Spicy 34.21%
    Amber 34.07%
    Balsamic 32.83%
    Mint 31.26%
    Sandalwood 30.19%
    Dry 28.88%
    Cooling 28.3%

     

    Flavor
    Bitter 41.47%
    Sweet 34.66%
    Herbal 28.47%
    Odorless 25.93%
    Pine 25.11%
    Woody 24.97%
    Balsam 24.75%
    Sweet-like 23.77%
    Fatty 23.25%
    Earthy 22.6%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.0

    pKa est.
    4.43 (weak acid)

    Molecular weight
    785.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    1055°C

    Flash point

    • 255.79 ˚C est.

  • Synonyms

    • ginsenoside F2
    • 62025-49-4
    • ginsenoside-F2
    • CHEBI:77145
    • DTXSID20432763
    • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((2S)-6-methyl-2-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyhept-5-en-2-yl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-yl)oxy)oxane-3,4,5-triol
    • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
    • RefChem:143211
    • DTXCID90383591
    • 20(S)-Ginsenoside F2
    • MFCD06410948
    • 20-(S)-Ginsenoside F2
    • CHEMBL1095007
    • 20(S)-Ginsenoside-F2
    • GinsenosideF2
    • (3ss,12ss)-12-Hydroxydammar-24-ene-3,20-diyl bis-ss-D-glucopyranoside
    • Sg(S)-ginsenoside f2
    • (20S)-ginsenoside F2
    • orb1303570
    • SCHEMBL17576511
    • BDBM50317538
    • s9044
    • AKOS037514666
    • CCG-270474
    • EBC-616288
    • OG13740
    • (2S,3R,4S,5S,6R)-2-{[(2S)-2-[(1S,3aR,3bR,5aR,7S,9aR,9bR,11R,11aR)-11-hydroxy-3a,3b,6,6,9a-pentamethyl-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-6-methylhept-5-en-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
    • DA-73724
    • MS-31437
    • HY-125848
    • CS-0009605
    • C20779
    • 025S494
    • Q27146699
    • 3beta,20-bis(beta-D-glucopyranosyloxy)dammar-24-en-12beta-ol
    • 3beta-(beta-D-Glucopyranosyloxy)-12beta-hydroxydammar-24-en-20-yl beta-D-glucopyranoside
    • (2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-17-[(1S)-1,5-dimethyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hex-4-enyl]-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
    • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R, 17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S, 5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2, 3,5,6,7,9,11,12,13,15,16, 17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
    • (3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl beta-D-glucopyranoside
    • 62025-49-4

  • Applications

    Ginsenoside F2 (CAS 62025-49-4) is primarily considered in formulations as a cosmetic active ingredient and skin-conditioning component, with potential surfactant-like behavior that can aid mild emulsification in personal-care products. It is also studied as a natural surfactant or formulation aid for cleaning and household products, where its glycoside structure can modulate surface activity. In pharmaceutical and nutraceutical research, it is evaluated as a bioactive saponin for extract-based formulations and as a component in research-grade formulations. For coatings and inks, F2 may serve as a surface-active additive to influence wetting and dispersion of natural polymer systems. In polymer/plastics contexts, it is explored as a plant-derived glycoside additive that can interact with polymers, subject to regulatory and formulation limits. Availability and use are contingent on regulatory status and supplier quality.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.22
    methanol 19.95
    isopropanol 0.93
    water 0.1
    ethyl acetate 3.03
    n-propanol 1.97
    acetone 6.33
    n-butanol 0.88
    acetonitrile 1.76
    DMF 37.36
    toluene 1.02
    isobutanol 0.8
    1,4-dioxane 12.43
    methyl acetate 3.36
    THF 28.78
    2-butanone 3.85
    n-pentanol 0.88
    sec-butanol 0.62
    n-hexane 0.05
    ethylene glycol 3.7
    NMP 50.08
    cyclohexane 0.09
    DMSO 49.39
    n-butyl acetate 1.51
    n-octanol 1.08
    chloroform 6.19
    n-propyl acetate 1.55
    acetic acid 30.79
    dichloromethane 5.45
    cyclohexanone 6.44
    propylene glycol 3.33
    isopropyl acetate 1.98
    DMAc 36.65
    2-ethoxyethanol 10.6
    isopentanol 0.58
    n-heptane 0.07
    ethyl formate 3.24
    1,2-dichloroethane 2.63
    n-hexanol 0.83
    2-methoxyethanol 21.86
    isobutyl acetate 0.95
    tetrachloromethane 0.88
    n-pentyl acetate 2.79
    transcutol 17.35
    n-heptanol 1.39
    ethylbenzene 0.43
    MIBK 1.64
    2-propoxyethanol 12.33
    tert-butanol 0.79
    MTBE 0.86
    2-butoxyethanol 9.14
    propionic acid 4.35
    o-xylene 0.65
    formic acid 25.79
    diethyl ether 1.35
    m-xylene 0.73
    p-xylene 0.53
    chlorobenzene 1.29
    dimethyl carbonate 6.95
    n-octane 0.04
    formamide 20.21
    cyclopentanone 15.5
    2-pentanone 2.85
    anisole 2.04
    cyclopentyl methyl ether 4.44
    gamma-butyrolactone 20.97
    1-methoxy-2-propanol 10.82
    pyridine 7.84
    3-pentanone 2.47
    furfural 20.08
    n-dodecane 0.03
    diethylene glycol 12.86
    diisopropyl ether 0.32
    tert-amyl alcohol 0.65
    acetylacetone 9.0
    n-hexadecane 0.03
    acetophenone 3.11
    methyl propionate 4.45
    isopentyl acetate 1.39
    trichloroethylene 8.58
    n-nonanol 1.15
    cyclohexanol 0.83
    benzyl alcohol 2.61
    2-ethylhexanol 0.49
    isooctanol 0.94
    dipropyl ether 1.1
    1,2-dichlorobenzene 1.36
    ethyl lactate 2.56
    propylene carbonate 7.06
    n-methylformamide 16.88
    2-pentanol 0.41
    n-pentane 0.05
    1-propoxy-2-propanol 5.39
    1-methoxy-2-propyl acetate 5.82
    2-(2-methoxypropoxy) propanol 5.73
    mesitylene 0.39
    ε-caprolactone 7.34
    p-cymene 0.39
    epichlorohydrin 17.71
    1,1,1-trichloroethane 1.61
    2-aminoethanol 6.01
    morpholine-4-carbaldehyde 45.62
    sulfolane 44.63
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 4.61
    n-hexyl acetate 2.79
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 8.6
    sec-butyl acetate 0.94
    tert-butyl acetate 2.22
    decalin 0.05
    glycerin 10.63
    diglyme 17.95
    acrylic acid 8.66
    isopropyl myristate 0.65
    n-butyric acid 4.28
    acetyl acetate 4.6
    di(2-ethylhexyl) phthalate 1.46
    ethyl propionate 1.55
    nitromethane 36.1
    1,2-diethoxyethane 3.24
    benzonitrile 1.62
    trioctyl phosphate 0.94
    1-bromopropane 0.68
    gamma-valerolactone 43.06
    n-decanol 0.61
    triethyl phosphate 1.16
    4-methyl-2-pentanol 0.34
    propionitrile 1.12
    vinylene carbonate 8.55
    1,1,2-trichlorotrifluoroethane 29.01
    DMS 3.53
    cumene 0.3
    2-octanol 0.62
    2-hexanone 1.64
    octyl acetate 1.24
    limonene 0.48
    1,2-dimethoxyethane 11.56
    ethyl orthosilicate 1.05
    tributyl phosphate 0.77
    diacetone alcohol 4.64
    N,N-dimethylaniline 1.72
    acrylonitrile 2.81
    aniline 1.72
    1,3-propanediol 5.28
    bromobenzene 1.16
    dibromomethane 2.37
    1,1,2,2-tetrachloroethane 5.56
    2-methyl-cyclohexyl acetate 1.62
    tetrabutyl urea 1.44
    diisobutyl methanol 0.3
    2-phenylethanol 2.65
    styrene 0.5
    dioctyl adipate 1.58
    dimethyl sulfate 16.05
    ethyl butyrate 1.45
    methyl lactate 7.98
    butyl lactate 3.48
    diethyl carbonate 0.96
    propanediol butyl ether 7.98
    triethyl orthoformate 1.62
    p-tert-butyltoluene 0.4
    methyl 4-tert-butylbenzoate 5.29
    morpholine 13.32
    tert-butylamine 0.25
    n-dodecanol 0.33
    dimethoxymethane 22.06
    ethylene carbonate 5.37
    cyrene 12.02
    2-ethoxyethyl acetate 7.19
    2-ethylhexyl acetate 1.09
    1,2,4-trichlorobenzene 2.23
    4-methylpyridine 3.74
    dibutyl ether 0.59
    2,6-dimethyl-4-heptanol 0.3
    DEF 5.82
    dimethyl isosorbide 11.55
    tetrachloroethylene 4.72
    eugenol 5.41
    triacetin 6.46
    span 80 5.44
    1,4-butanediol 2.17
    1,1-dichloroethane 1.41
    2-methyl-1-pentanol 0.57
    methyl formate 14.66
    2-methyl-1-butanol 0.6
    n-decane 0.07
    butyronitrile 0.79
    3,7-dimethyl-1-octanol 0.61
    1-chlorooctane 0.34
    1-chlorotetradecane 0.09
    n-nonane 0.05
    undecane 0.04
    tert-butylcyclohexane 0.04
    cyclooctane 0.05
    cyclopentanol 1.82
    tetrahydropyran 3.51
    tert-amyl methyl ether 0.81
    2,5,8-trioxanonane 10.7
    1-hexene 0.16
    2-isopropoxyethanol 4.51
    2,2,2-trifluoroethanol 11.18
    methyl butyrate 2.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction