ginkgolide-C
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Identifiers
Molecular formula
C20H24O11SMILES
CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5O)C(C)(C)C)C(C(=O)OC6O4)O)O
Safety labels
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Odor profile
Fragrance Odorless 68.52% Spicy 22.87% Sweet 22.07% Woody 20.49% Cooling 19.99% Mint 17.2% Milky 15.89% Savory 15.11% Burnt 14.82% Dry 14.73% Flavor Bitter 90.05% Bland 23.8% Sweet-like 22.96% Cedarleaf 22.07% Odorless 19.63% Parsley 19.39% Ripe apricot 19.37% Red fruit 19.26% Fenugreek 19.02% Lovage 19.01% Odor impact est.
Low -
Properties
XLogP3-AA
-1.4pKa est.
4.69 (weak acid)Molecular weight
440.4 g/molVapor pressure est.
- hPa @ 20°C
- hPa @ 25°C
Evaporation rate
ModerateBoiling point est.
2998°CMelting point expt.
- 280 °C
Flash point
- 213.0 ˚C est.
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Synonyms
- GINKGOKIDE C
- ginkgolide-C
- 1,7-Dihydroxy-ginkgolide A
- C20H24O11
- 1alpha,7beta-Dihydroxyginkgolide A
- Ginkgolide C (~90%)
- HMS5082O11
- NSC335757
- NSC-335757
- CID 24721502
- LS-14795
- DB-043165
- 1,7-Dihydroxy-(1alpha,7beta)-Ginkgolide A
- L001208
- Ginkgolide C
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Applications
ginkgolide-C is a natural diterpene lactone isolated from Ginkgo biloba; in practice, it is commonly used as a reference standard and quantitative analytical marker for quality control of Ginkgo biloba extracts (e.g., LC-MS/HPLC). It is also studied as a bioactive lead related to PAF receptor antagonism, so it appears in pharmaceutical and biomedical research as a model compound. Additionally, ginkgolide-C serves as a target compound in isolation and characterization workflows for Ginkgo constituents. It may be evaluated in cosmetic and personal care research as a plant-derived bioactive component and used as a reference in formulation feasibility studies. In academic settings, it functions as reference material for receptor-binding and structure-activity investigations.
gpt-5-nano
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Solubility @25˚C
Solvent Solubility (g/L) ethanol 31.46 methanol 80.74 isopropanol 17.33 water 3.95 ethyl acetate 30.35 n-propanol 19.5 acetone 65.32 n-butanol 17.19 acetonitrile 37.82 DMF 221.82 toluene 8.13 isobutanol 10.74 1,4-dioxane 64.35 methyl acetate 39.29 THF 143.43 2-butanone 39.9 n-pentanol 9.84 sec-butanol 11.05 n-hexane 0.43 ethylene glycol 41.49 NMP 289.34 cyclohexane 1.13 DMSO 299.13 n-butyl acetate 20.71 n-octanol 4.89 chloroform 45.17 n-propyl acetate 18.2 acetic acid 169.7 dichloromethane 46.53 cyclohexanone 71.35 propylene glycol 27.22 isopropyl acetate 18.83 DMAc 158.38 2-ethoxyethanol 53.1 isopentanol 10.71 n-heptane 0.57 ethyl formate 45.47 1,2-dichloroethane 32.03 n-hexanol 12.86 2-methoxyethanol 146.0 isobutyl acetate 8.88 tetrachloromethane 8.03 n-pentyl acetate 14.46 transcutol 27.18 n-heptanol 8.06 ethylbenzene 3.53 MIBK 16.22 2-propoxyethanol 75.49 tert-butanol 12.62 MTBE 5.69 2-butoxyethanol 35.12 propionic acid 43.86 o-xylene 5.05 formic acid 214.31 diethyl ether 11.58 m-xylene 5.27 p-xylene 4.15 chlorobenzene 11.26 dimethyl carbonate 58.78 n-octane 0.3 formamide 227.94 cyclopentanone 134.89 2-pentanone 32.42 anisole 8.68 cyclopentyl methyl ether 28.14 gamma-butyrolactone 200.99 1-methoxy-2-propanol 77.05 pyridine 55.24 3-pentanone 23.19 furfural 161.99 n-dodecane 0.22 diethylene glycol 97.89 diisopropyl ether 2.59 tert-amyl alcohol 8.88 acetylacetone 60.45 n-hexadecane 0.26 acetophenone 19.95 methyl propionate 42.65 isopentyl acetate 14.84 trichloroethylene 74.47 n-nonanol 4.89 cyclohexanol 16.33 benzyl alcohol 17.96 2-ethylhexanol 5.95 isooctanol 5.4 dipropyl ether 6.89 1,2-dichlorobenzene 12.24 ethyl lactate 22.95 propylene carbonate 83.71 n-methylformamide 150.3 2-pentanol 7.56 n-pentane 0.58 1-propoxy-2-propanol 34.13 1-methoxy-2-propyl acetate 34.84 2-(2-methoxypropoxy) propanol 18.53 mesitylene 2.79 ε-caprolactone 77.3 p-cymene 3.29 epichlorohydrin 137.51 1,1,1-trichloroethane 18.79 2-aminoethanol 41.23 morpholine-4-carbaldehyde 216.52 sulfolane 271.41 2,2,4-trimethylpentane 0.25 2-methyltetrahydrofuran 45.56 n-hexyl acetate 13.91 isooctane 0.18 2-(2-butoxyethoxy)ethanol 23.32 sec-butyl acetate 9.94 tert-butyl acetate 15.58 decalin 0.55 glycerin 94.31 diglyme 45.82 acrylic acid 71.98 isopropyl myristate 4.3 n-butyric acid 50.54 acetyl acetate 35.48 di(2-ethylhexyl) phthalate 8.51 ethyl propionate 16.67 nitromethane 260.11 1,2-diethoxyethane 10.0 benzonitrile 22.07 trioctyl phosphate 7.75 1-bromopropane 9.29 gamma-valerolactone 235.15 n-decanol 3.26 triethyl phosphate 10.3 4-methyl-2-pentanol 4.55 propionitrile 21.61 vinylene carbonate 90.27 1,1,2-trichlorotrifluoroethane 140.74 DMS 23.59 cumene 2.26 2-octanol 3.86 2-hexanone 17.21 octyl acetate 7.55 limonene 4.59 1,2-dimethoxyethane 59.33 ethyl orthosilicate 7.75 tributyl phosphate 7.1 diacetone alcohol 34.63 N,N-dimethylaniline 7.41 acrylonitrile 46.36 aniline 17.49 1,3-propanediol 58.85 bromobenzene 9.51 dibromomethane 24.36 1,1,2,2-tetrachloroethane 47.78 2-methyl-cyclohexyl acetate 13.86 tetrabutyl urea 11.48 diisobutyl methanol 2.93 2-phenylethanol 21.96 styrene 3.66 dioctyl adipate 8.78 dimethyl sulfate 118.98 ethyl butyrate 14.0 methyl lactate 65.63 butyl lactate 15.79 diethyl carbonate 11.23 propanediol butyl ether 20.93 triethyl orthoformate 10.52 p-tert-butyltoluene 2.93 methyl 4-tert-butylbenzoate 18.23 morpholine 82.04 tert-butylamine 3.83 n-dodecanol 2.17 dimethoxymethane 106.28 ethylene carbonate 67.41 cyrene 56.61 2-ethoxyethyl acetate 23.82 2-ethylhexyl acetate 11.76 1,2,4-trichlorobenzene 17.6 4-methylpyridine 38.08 dibutyl ether 2.99 2,6-dimethyl-4-heptanol 2.93 DEF 51.76 dimethyl isosorbide 42.75 tetrachloroethylene 38.57 eugenol 20.31 triacetin 20.46 span 80 18.43 1,4-butanediol 21.23 1,1-dichloroethane 18.94 2-methyl-1-pentanol 7.16 methyl formate 128.44 2-methyl-1-butanol 9.69 n-decane 0.4 butyronitrile 19.62 3,7-dimethyl-1-octanol 3.69 1-chlorooctane 1.99 1-chlorotetradecane 0.8 n-nonane 0.34 undecane 0.28 tert-butylcyclohexane 0.34 cyclooctane 0.49 cyclopentanol 30.72 tetrahydropyran 30.7 tert-amyl methyl ether 6.1 2,5,8-trioxanonane 28.84 1-hexene 1.78 2-isopropoxyethanol 25.81 2,2,2-trifluoroethanol 106.42 methyl butyrate 23.8 Scent© AI
| Maximum acceptable concentrations in the finished product (%) | |||
|---|---|---|---|
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Category 1
Products applied to the lips
|
No restriction |
Category 7A
Rinse-off products applied to the hair with some hand contact
|
No restriction |
|
Category 2
Products applied to the axillae
|
No restriction |
Category 7B
Leave-on products applied to the hair with some hand contact
|
No restriction |
|
Category 3
Products applied to the face/body using fingertips
|
No restriction |
Category 8
Products with significant anogenital exposure
|
No restriction |
|
Category 4
Products related to fine fragrance
|
No restriction |
Category 9
Products with body and hand exposure, primarily rinse off
|
No restriction |
|
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
|
No restriction |
Category 10A
Household care products with mostly hand contact
|
No restriction |
|
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
|
No restriction |
Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
|
No restriction |
|
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
|
No restriction |
Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
|
No restriction |
|
Category 5D
Baby Creams, baby Oils and baby talc
|
No restriction |
Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
|
No restriction |
|
Category 6
Products with oral and lip exposure
|
No restriction |
Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
|
No restriction |