Garciduol C

Overview IFRA Request a quote

  • Identifiers

    CAS number
    182127-82-8

    Molecular formula
    C27H18O9

    SMILES
    COC1=C(C(=C(C(=C1)O)C(=O)C2=CC=CC=C2)O)C3=CC(=C(C4=C3OC5=C(C4=O)C=CC=C5O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 55.84%
    Phenolic 51.94%
    Burnt 32.28%
    Spicy 26.51%
    Balsamic 26.04%
    Smoky 24.5%
    Medicinal 23.08%
    Fruity 22.2%
    Bitter 21.94%
    Dry 21.55%

     

    Flavor
    Bitter 96.94%
    Odorless 27.07%
    Bland 22.05%
    Sweet-like 19.96%
    Cedarleaf 19.54%
    Lovage 19.03%
    Nitrile 18.88%
    Very strong 18.87%
    Parsley 18.61%
    Indole 18.53%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.2

    pKa est.
    9.27 (weak base)

    Molecular weight
    486.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1694°C

    Flash point

    • 306.2 ˚C est.

  • Synonyms

    • Garciduol C
    • 4-(3-benzoyl-2,4-dihydroxy-6-methoxyphenyl)-1,2,5-trihydroxy-9H-xanthen-9-one
    • 4-(3-benzoyl-2,4-dihydroxy-6-methoxyphenyl)-1,2,5-trihydroxyxanthen-9-one
    • RefChem:142632
    • CHEBI:192466
    • DTXSID601140039
    • 182127-82-8
    • 182127-82-8

  • Applications

    Garciduol C (CAS 182127-82-8) is a polyphenolic benzophenone-like compound primarily encountered as a specialty intermediate in organic synthesis; in practical applications, it is often evaluated as an antioxidant additive and stabilizer for cosmetics/personal care formulations and for polymeric materials and coatings to enhance oxidative resistance. It can also serve as a chemical building block in the synthesis of related aromatic compounds used in fragrance chemistry and may be explored for use in specialty coatings or inks as a functional additive, subject to formulation constraints and regulatory requirements.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 17.13
    methanol 12.34
    isopropanol 10.82
    water 0.02
    ethyl acetate 9.85
    n-propanol 15.49
    acetone 25.58
    n-butanol 8.01
    acetonitrile 4.17
    DMF 70.5
    toluene 1.86
    isobutanol 6.57
    1,4-dioxane 25.97
    methyl acetate 14.84
    THF 97.33
    2-butanone 31.15
    n-pentanol 4.89
    sec-butanol 10.68
    n-hexane 0.1
    ethylene glycol 12.51
    NMP 65.65
    cyclohexane 0.2
    DMSO 221.99
    n-butyl acetate 3.7
    n-octanol 2.38
    chloroform 2.86
    n-propyl acetate 4.67
    acetic acid 28.44
    dichloromethane 3.41
    cyclohexanone 28.83
    propylene glycol 12.32
    isopropyl acetate 5.04
    DMAc 84.56
    2-ethoxyethanol 21.57
    isopentanol 4.27
    n-heptane 0.11
    ethyl formate 7.74
    1,2-dichloroethane 4.47
    n-hexanol 3.25
    2-methoxyethanol 53.31
    isobutyl acetate 1.67
    tetrachloromethane 0.43
    n-pentyl acetate 3.88
    transcutol 13.74
    n-heptanol 2.56
    ethylbenzene 0.66
    MIBK 4.13
    2-propoxyethanol 19.75
    tert-butanol 6.81
    MTBE 3.13
    2-butoxyethanol 8.96
    propionic acid 15.99
    o-xylene 0.97
    formic acid 18.56
    diethyl ether 6.05
    m-xylene 0.75
    p-xylene 0.73
    chlorobenzene 1.0
    dimethyl carbonate 10.9
    n-octane 0.09
    formamide 28.15
    cyclopentanone 57.46
    2-pentanone 14.13
    anisole 2.27
    cyclopentyl methyl ether 10.29
    gamma-butyrolactone 52.84
    1-methoxy-2-propanol 30.47
    pyridine 19.93
    3-pentanone 10.48
    furfural 20.74
    n-dodecane 0.1
    diethylene glycol 20.16
    diisopropyl ether 0.71
    tert-amyl alcohol 6.79
    acetylacetone 14.54
    n-hexadecane 0.12
    acetophenone 4.06
    methyl propionate 15.92
    isopentyl acetate 2.43
    trichloroethylene 7.26
    n-nonanol 2.64
    cyclohexanol 7.3
    benzyl alcohol 4.39
    2-ethylhexanol 1.4
    isooctanol 1.64
    dipropyl ether 2.86
    1,2-dichlorobenzene 0.73
    ethyl lactate 5.12
    propylene carbonate 9.92
    n-methylformamide 35.01
    2-pentanol 4.2
    n-pentane 0.14
    1-propoxy-2-propanol 11.0
    1-methoxy-2-propyl acetate 7.87
    2-(2-methoxypropoxy) propanol 6.93
    mesitylene 0.31
    ε-caprolactone 21.82
    p-cymene 0.45
    epichlorohydrin 38.65
    1,1,1-trichloroethane 1.54
    2-aminoethanol 16.91
    morpholine-4-carbaldehyde 47.01
    sulfolane 86.67
    2,2,4-trimethylpentane 0.06
    2-methyltetrahydrofuran 21.86
    n-hexyl acetate 3.95
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 9.67
    sec-butyl acetate 2.48
    tert-butyl acetate 4.13
    decalin 0.08
    glycerin 28.71
    diglyme 14.07
    acrylic acid 16.97
    isopropyl myristate 1.75
    n-butyric acid 12.08
    acetyl acetate 4.17
    di(2-ethylhexyl) phthalate 1.84
    ethyl propionate 4.73
    nitromethane 43.44
    1,2-diethoxyethane 4.9
    benzonitrile 2.59
    trioctyl phosphate 2.02
    1-bromopropane 2.44
    gamma-valerolactone 75.18
    n-decanol 1.97
    triethyl phosphate 1.78
    4-methyl-2-pentanol 1.51
    propionitrile 5.99
    vinylene carbonate 8.01
    1,1,2-trichlorotrifluoroethane 31.91
    DMS 4.77
    cumene 0.34
    2-octanol 1.82
    2-hexanone 6.98
    octyl acetate 2.74
    limonene 0.79
    1,2-dimethoxyethane 21.27
    ethyl orthosilicate 1.51
    tributyl phosphate 1.82
    diacetone alcohol 12.16
    N,N-dimethylaniline 1.66
    acrylonitrile 9.21
    aniline 4.95
    1,3-propanediol 22.01
    bromobenzene 0.64
    dibromomethane 2.06
    1,1,2,2-tetrachloroethane 6.82
    2-methyl-cyclohexyl acetate 2.35
    tetrabutyl urea 3.42
    diisobutyl methanol 0.78
    2-phenylethanol 3.79
    styrene 0.72
    dioctyl adipate 2.85
    dimethyl sulfate 20.7
    ethyl butyrate 2.83
    methyl lactate 17.21
    butyl lactate 4.62
    diethyl carbonate 1.72
    propanediol butyl ether 7.75
    triethyl orthoformate 2.47
    p-tert-butyltoluene 0.41
    methyl 4-tert-butylbenzoate 4.01
    morpholine 44.91
    tert-butylamine 1.79
    n-dodecanol 1.44
    dimethoxymethane 34.39
    ethylene carbonate 7.54
    cyrene 10.57
    2-ethoxyethyl acetate 6.54
    2-ethylhexyl acetate 1.89
    1,2,4-trichlorobenzene 1.51
    4-methylpyridine 9.25
    dibutyl ether 2.0
    2,6-dimethyl-4-heptanol 0.78
    DEF 17.97
    dimethyl isosorbide 9.87
    tetrachloroethylene 4.38
    eugenol 4.77
    triacetin 4.69
    span 80 6.25
    1,4-butanediol 6.62
    1,1-dichloroethane 2.7
    2-methyl-1-pentanol 2.87
    methyl formate 22.12
    2-methyl-1-butanol 5.28
    n-decane 0.18
    butyronitrile 4.11
    3,7-dimethyl-1-octanol 1.39
    1-chlorooctane 0.79
    1-chlorotetradecane 0.36
    n-nonane 0.14
    undecane 0.13
    tert-butylcyclohexane 0.05
    cyclooctane 0.08
    cyclopentanol 14.34
    tetrahydropyran 17.87
    tert-amyl methyl ether 3.32
    2,5,8-trioxanonane 11.23
    1-hexene 0.69
    2-isopropoxyethanol 9.82
    2,2,2-trifluoroethanol 9.87
    methyl butyrate 6.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction