Ganodermanontriol

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  • Identifiers

    CAS number
    106518-63-2

    Molecular formula
    C30H48O4

    SMILES
    C[C@H](CC[C@@H]([C@@](C)(CO)O)O)[C@H]1CC[C@@]2([C@@]1(CC=C3C2=CC[C@@H]4[C@@]3(CCC(=O)C4(C)C)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 84.78%
    Amber 56.72%
    Sandalwood 52.12%
    Musk 46.08%
    Dry 44.77%
    Cedar 43.34%
    Vetiver 35.99%
    Powdery 34.56%
    Balsamic 33.06%
    Animal 30.05%

     

    Flavor
    Woody 54.72%
    Bitter 37.27%
    Sweet 35.1%
    Balsam 32.42%
    Pine 31.39%
    Herbal 29.18%
    Camphor 27.23%
    Mild 23.25%
    Sandalwood 23.02%
    Wood 22.91%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.8

    pKa est.
    7.11 (neutral)

    Molecular weight
    472.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    145°C

    Flash point

    • 266.69 ˚C est.

  • Synonyms

    • Ganodermanontriol
    • 106518-63-2
    • (+)-Ganodermanontriol
    • 6NB33MKR8F
    • (5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R,5S,6R)-5,6,7-trihydroxy-6-methylheptan-2-yl]-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
    • DTXSID10910025
    • GNDT Triterpene
    • (5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-((2R,5S,6R)-5,6,7-trihydroxy-6-methylheptan-2-yl)-1,2,5,6,12,15,16,17-octahydrocyclopenta(a)phenanthren-3-one
    • RefChem:142516
    • DTXCID301764319
    • 3-oxo-lanosta-7,9(11)-dien-24S,25R,26-triol
    • 26-Hydroxyganodermanondiol
    • CHEMBL1915763
    • C30H48O4
    • (24S,25R)-24,25,26-Trihydroxylanosta-7,9(11)-dien-3-one
    • orb1709637
    • Lanosta-7,9(11)-dien-3-one, 24,25,26-trihydroxy-, (24S,25R)-
    • SCHEMBL29479877
    • CHEBI:68858
    • HY-N1506
    • BDBM50356923
    • AKOS040733229
    • CS-0017049
    • Q27137215
    • Lanosta-7\,9(11)-dien-3-one\, 24\,25\,26-trihydroxy-\, (24S\,25R)-
    • (5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-((2R,5S,6R)-5,6,7-trihydroxy-6-methylheptan-2-yl)-4,5,6,10,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
    • (5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(1R,4S,5R)-4,5,6-trihydroxy-1,5-dimethyl-hexyl]-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
    • 106518-63-2

  • Applications

    Ganodermanontriol (CAS 106518-63-2) is a lanostane-type triterpenoid isolated from Ganoderma species. In product development contexts, it is commonly evaluated as a bioactive natural product with potential immunomodulatory and anti-inflammatory activity. Potential applications include cosmetics and personal care as a skin-active ingredient or formulation additive; in pharmaceutical research as a lead compound or reference for immunomodulatory effects; applications in functional foods or nutraceuticals; and use in chemical synthesis as an intermediate for related triterpenoids.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.1
    methanol 10.54
    isopropanol 5.55
    water 0.01
    ethyl acetate 2.79
    n-propanol 9.32
    acetone 5.66
    n-butanol 6.0
    acetonitrile 1.18
    DMF 33.05
    toluene 2.41
    isobutanol 4.4
    1,4-dioxane 18.37
    methyl acetate 2.72
    THF 29.74
    2-butanone 5.27
    n-pentanol 4.29
    sec-butanol 2.55
    n-hexane 0.16
    ethylene glycol 1.13
    NMP 17.38
    cyclohexane 0.15
    DMSO 12.73
    n-butyl acetate 2.85
    n-octanol 2.8
    chloroform 9.86
    n-propyl acetate 2.38
    acetic acid 6.51
    dichloromethane 5.25
    cyclohexanone 8.02
    propylene glycol 2.74
    isopropyl acetate 2.98
    DMAc 22.99
    2-ethoxyethanol 15.65
    isopentanol 3.81
    n-heptane 0.14
    ethyl formate 2.09
    1,2-dichloroethane 2.88
    n-hexanol 4.61
    2-methoxyethanol 25.89
    isobutyl acetate 2.33
    tetrachloromethane 1.42
    n-pentyl acetate 5.79
    transcutol 35.57
    n-heptanol 5.0
    ethylbenzene 1.36
    MIBK 3.91
    2-propoxyethanol 31.2
    tert-butanol 3.58
    MTBE 2.79
    2-butoxyethanol 20.93
    propionic acid 3.42
    o-xylene 1.51
    formic acid 3.24
    diethyl ether 3.53
    m-xylene 1.81
    p-xylene 1.41
    chlorobenzene 2.36
    dimethyl carbonate 3.9
    n-octane 0.08
    formamide 4.1
    cyclopentanone 11.66
    2-pentanone 4.54
    anisole 5.12
    cyclopentyl methyl ether 5.86
    gamma-butyrolactone 10.28
    1-methoxy-2-propanol 23.71
    pyridine 10.23
    3-pentanone 3.14
    furfural 10.6
    n-dodecane 0.04
    diethylene glycol 15.16
    diisopropyl ether 0.92
    tert-amyl alcohol 2.15
    acetylacetone 6.58
    n-hexadecane 0.05
    acetophenone 4.69
    methyl propionate 4.05
    isopentyl acetate 3.67
    trichloroethylene 8.31
    n-nonanol 3.31
    cyclohexanol 2.2
    benzyl alcohol 5.78
    2-ethylhexanol 1.84
    isooctanol 3.71
    dipropyl ether 2.62
    1,2-dichlorobenzene 2.43
    ethyl lactate 3.03
    propylene carbonate 3.98
    n-methylformamide 8.58
    2-pentanol 2.11
    n-pentane 0.15
    1-propoxy-2-propanol 16.58
    1-methoxy-2-propyl acetate 8.97
    2-(2-methoxypropoxy) propanol 11.69
    mesitylene 1.0
    ε-caprolactone 7.63
    p-cymene 0.99
    epichlorohydrin 13.8
    1,1,1-trichloroethane 2.35
    2-aminoethanol 5.25
    morpholine-4-carbaldehyde 31.42
    sulfolane 13.87
    2,2,4-trimethylpentane 0.11
    2-methyltetrahydrofuran 5.84
    n-hexyl acetate 5.98
    isooctane 0.11
    2-(2-butoxyethoxy)ethanol 18.44
    sec-butyl acetate 1.78
    tert-butyl acetate 4.16
    decalin 0.15
    glycerin 5.72
    diglyme 30.91
    acrylic acid 3.55
    isopropyl myristate 1.48
    n-butyric acid 5.71
    acetyl acetate 2.77
    di(2-ethylhexyl) phthalate 3.57
    ethyl propionate 2.16
    nitromethane 7.68
    1,2-diethoxyethane 6.38
    benzonitrile 2.87
    trioctyl phosphate 2.16
    1-bromopropane 1.39
    gamma-valerolactone 29.67
    n-decanol 1.61
    triethyl phosphate 1.85
    4-methyl-2-pentanol 1.85
    propionitrile 1.82
    vinylene carbonate 5.11
    1,1,2-trichlorotrifluoroethane 13.91
    DMS 4.55
    cumene 0.99
    2-octanol 2.12
    2-hexanone 3.45
    octyl acetate 2.35
    limonene 1.08
    1,2-dimethoxyethane 19.05
    ethyl orthosilicate 2.16
    tributyl phosphate 1.69
    diacetone alcohol 7.41
    N,N-dimethylaniline 4.15
    acrylonitrile 2.67
    aniline 3.95
    1,3-propanediol 9.66
    bromobenzene 2.1
    dibromomethane 3.14
    1,1,2,2-tetrachloroethane 6.73
    2-methyl-cyclohexyl acetate 3.45
    tetrabutyl urea 2.86
    diisobutyl methanol 1.2
    2-phenylethanol 7.08
    styrene 1.45
    dioctyl adipate 3.28
    dimethyl sulfate 6.45
    ethyl butyrate 2.31
    methyl lactate 5.59
    butyl lactate 7.27
    diethyl carbonate 1.46
    propanediol butyl ether 14.64
    triethyl orthoformate 3.16
    p-tert-butyltoluene 1.06
    methyl 4-tert-butylbenzoate 9.38
    morpholine 24.5
    tert-butylamine 1.39
    n-dodecanol 0.78
    dimethoxymethane 27.54
    ethylene carbonate 3.94
    cyrene 11.69
    2-ethoxyethyl acetate 11.64
    2-ethylhexyl acetate 2.56
    1,2,4-trichlorobenzene 3.58
    4-methylpyridine 6.41
    dibutyl ether 1.47
    2,6-dimethyl-4-heptanol 1.2
    DEF 5.96
    dimethyl isosorbide 16.51
    tetrachloroethylene 5.49
    eugenol 11.7
    triacetin 7.48
    span 80 10.14
    1,4-butanediol 3.42
    1,1-dichloroethane 2.12
    2-methyl-1-pentanol 2.77
    methyl formate 4.58
    2-methyl-1-butanol 3.13
    n-decane 0.12
    butyronitrile 1.92
    3,7-dimethyl-1-octanol 2.08
    1-chlorooctane 0.69
    1-chlorotetradecane 0.15
    n-nonane 0.1
    undecane 0.06
    tert-butylcyclohexane 0.16
    cyclooctane 0.09
    cyclopentanol 3.18
    tetrahydropyran 7.34
    tert-amyl methyl ether 1.99
    2,5,8-trioxanonane 17.07
    1-hexene 0.6
    2-isopropoxyethanol 9.61
    2,2,2-trifluoroethanol 2.55
    methyl butyrate 2.74

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction