Ganoderiol E

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  • Identifiers

    CAS number
    114567-46-3

    Molecular formula
    C30H48O4

    SMILES
    C[C@H](CCC=C(CO)CO)[C@H]1CC[C@@]2([C@@]1(CCC3=C2C(=O)C[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 88.96%
    Sandalwood 58.01%
    Amber 57.9%
    Cedar 47.25%
    Dry 46.85%
    Musk 42.49%
    Balsamic 38.2%
    Vetiver 37.27%
    Powdery 36.87%
    Animal 29.49%

     

    Flavor
    Woody 60.12%
    Bitter 38.1%
    Balsam 34.53%
    Sweet 31.94%
    Herbal 30.7%
    Pine 28.16%
    Camphor 26.76%
    Spicy 25.96%
    Wood 23.54%
    Sandalwood 22.79%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.5

    pKa est.
    7.03 (neutral)

    Molecular weight
    472.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    135°C

    Flash point

    • 270.98 ˚C est.

  • Synonyms

    • Ganoderiol E
    • 114567-46-3
    • RefChem:142481
    • DTXSID501317932
    • 3beta,26,27-Trihydroxylanosta-8,24-dien-7-one
    • 114567-46-3

  • Applications

    Ganoderiol E (CAS 114567-46-3) is a lanostane-type triterpenoid isolated from Ganoderma species. In practical applications, it is commonly considered a potential bioactive ingredient in cosmetics and personal care due to its reported antioxidant and anti-inflammatory activity, and it is also evaluated as a natural-product-derived scaffold in pharmaceutical discovery and lead optimization. In analytical and natural-products chemistry, it can serve as a reference material or starting point for structure-activity studies and for quality-control references in natural product libraries. The compound may be used by researchers in the natural-products supply chain as a chemical standard or for semi-synthetic work, with use typically subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 9.37
    methanol 8.84
    isopropanol 6.55
    water 0.01
    ethyl acetate 3.14
    n-propanol 9.76
    acetone 6.69
    n-butanol 6.8
    acetonitrile 1.39
    DMF 33.69
    toluene 2.65
    isobutanol 4.98
    1,4-dioxane 15.15
    methyl acetate 3.1
    THF 26.36
    2-butanone 6.62
    n-pentanol 4.36
    sec-butanol 2.58
    n-hexane 0.13
    ethylene glycol 1.18
    NMP 19.85
    cyclohexane 0.15
    DMSO 13.89
    n-butyl acetate 3.68
    n-octanol 2.36
    chloroform 11.69
    n-propyl acetate 2.72
    acetic acid 6.16
    dichloromethane 5.89
    cyclohexanone 10.49
    propylene glycol 2.44
    isopropyl acetate 3.38
    DMAc 25.38
    2-ethoxyethanol 12.94
    isopentanol 4.13
    n-heptane 0.12
    ethyl formate 2.43
    1,2-dichloroethane 3.75
    n-hexanol 4.99
    2-methoxyethanol 22.35
    isobutyl acetate 2.72
    tetrachloromethane 1.83
    n-pentyl acetate 6.21
    transcutol 23.57
    n-heptanol 4.52
    ethylbenzene 1.4
    MIBK 4.46
    2-propoxyethanol 27.82
    tert-butanol 3.98
    MTBE 2.54
    2-butoxyethanol 18.32
    propionic acid 3.76
    o-xylene 1.57
    formic acid 2.94
    diethyl ether 3.31
    m-xylene 1.94
    p-xylene 1.57
    chlorobenzene 2.96
    dimethyl carbonate 4.08
    n-octane 0.06
    formamide 4.0
    cyclopentanone 14.68
    2-pentanone 5.48
    anisole 4.59
    cyclopentyl methyl ether 5.64
    gamma-butyrolactone 11.54
    1-methoxy-2-propanol 21.31
    pyridine 10.73
    3-pentanone 4.02
    furfural 10.94
    n-dodecane 0.03
    diethylene glycol 14.21
    diisopropyl ether 0.83
    tert-amyl alcohol 2.16
    acetylacetone 7.09
    n-hexadecane 0.04
    acetophenone 5.08
    methyl propionate 4.53
    isopentyl acetate 4.5
    trichloroethylene 9.8
    n-nonanol 2.77
    cyclohexanol 2.65
    benzyl alcohol 5.89
    2-ethylhexanol 2.0
    isooctanol 3.39
    dipropyl ether 2.44
    1,2-dichlorobenzene 2.93
    ethyl lactate 3.23
    propylene carbonate 4.9
    n-methylformamide 8.8
    2-pentanol 2.2
    n-pentane 0.13
    1-propoxy-2-propanol 15.55
    1-methoxy-2-propyl acetate 9.7
    2-(2-methoxypropoxy) propanol 9.79
    mesitylene 1.02
    ε-caprolactone 8.62
    p-cymene 1.08
    epichlorohydrin 14.1
    1,1,1-trichloroethane 3.26
    2-aminoethanol 5.11
    morpholine-4-carbaldehyde 27.09
    sulfolane 15.67
    2,2,4-trimethylpentane 0.1
    2-methyltetrahydrofuran 5.78
    n-hexyl acetate 5.7
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 14.61
    sec-butyl acetate 1.99
    tert-butyl acetate 4.15
    decalin 0.13
    glycerin 5.27
    diglyme 25.31
    acrylic acid 3.86
    isopropyl myristate 1.43
    n-butyric acid 6.27
    acetyl acetate 2.97
    di(2-ethylhexyl) phthalate 3.71
    ethyl propionate 2.48
    nitromethane 8.04
    1,2-diethoxyethane 5.12
    benzonitrile 3.51
    trioctyl phosphate 2.33
    1-bromopropane 1.72
    gamma-valerolactone 28.98
    n-decanol 1.35
    triethyl phosphate 2.18
    4-methyl-2-pentanol 1.89
    propionitrile 2.48
    vinylene carbonate 6.11
    1,1,2-trichlorotrifluoroethane 14.29
    DMS 4.92
    cumene 1.01
    2-octanol 1.87
    2-hexanone 3.99
    octyl acetate 2.27
    limonene 1.17
    1,2-dimethoxyethane 15.95
    ethyl orthosilicate 2.37
    tributyl phosphate 1.84
    diacetone alcohol 7.46
    N,N-dimethylaniline 3.54
    acrylonitrile 3.53
    aniline 4.42
    1,3-propanediol 9.86
    bromobenzene 2.56
    dibromomethane 3.79
    1,1,2,2-tetrachloroethane 8.28
    2-methyl-cyclohexyl acetate 3.89
    tetrabutyl urea 3.2
    diisobutyl methanol 1.19
    2-phenylethanol 7.71
    styrene 1.42
    dioctyl adipate 3.2
    dimethyl sulfate 7.07
    ethyl butyrate 2.77
    methyl lactate 5.79
    butyl lactate 7.62
    diethyl carbonate 1.8
    propanediol butyl ether 12.05
    triethyl orthoformate 3.3
    p-tert-butyltoluene 1.08
    methyl 4-tert-butylbenzoate 9.17
    morpholine 20.69
    tert-butylamine 1.51
    n-dodecanol 0.66
    dimethoxymethane 23.73
    ethylene carbonate 4.74
    cyrene 11.16
    2-ethoxyethyl acetate 10.99
    2-ethylhexyl acetate 3.24
    1,2,4-trichlorobenzene 4.39
    4-methylpyridine 7.52
    dibutyl ether 1.21
    2,6-dimethyl-4-heptanol 1.19
    DEF 6.4
    dimethyl isosorbide 15.46
    tetrachloroethylene 6.4
    eugenol 11.43
    triacetin 6.9
    span 80 8.66
    1,4-butanediol 3.6
    1,1-dichloroethane 2.92
    2-methyl-1-pentanol 2.81
    methyl formate 4.87
    2-methyl-1-butanol 3.4
    n-decane 0.09
    butyronitrile 2.47
    3,7-dimethyl-1-octanol 1.83
    1-chlorooctane 0.61
    1-chlorotetradecane 0.13
    n-nonane 0.08
    undecane 0.05
    tert-butylcyclohexane 0.13
    cyclooctane 0.07
    cyclopentanol 3.94
    tetrahydropyran 7.01
    tert-amyl methyl ether 1.76
    2,5,8-trioxanonane 14.44
    1-hexene 0.57
    2-isopropoxyethanol 8.06
    2,2,2-trifluoroethanol 2.87
    methyl butyrate 3.28

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction