Ganoderic Acid G

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  • Identifiers

    CAS number
    98665-22-6

    Molecular formula
    C30H44O8

    SMILES
    C[C@H](CC(=O)CC(C)C(=O)O)[C@H]1CC(=O)[C@@]2([C@@]1([C@@H](C(=O)C3=C2[C@H](C[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)O)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 48.91%
    Odorless 48.03%
    Cooling 30.22%
    Mint 27.66%
    Dry 25.72%
    Spicy 24.04%
    Cedar 22.78%
    Sweet 21.68%
    Amber 21.42%
    Camphoreous 21.3%

     

    Flavor
    Bitter 87.05%
    Odorless 28.6%
    Bland 25.36%
    Sweet-like 22.19%
    Cedarleaf 21.53%
    Parsley 19.55%
    Ripe apricot 19.51%
    Leaves 19.31%
    Heather 19.16%
    Red fruit 19.15%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.7

    pKa est.
    4.32 (weak acid)

    Molecular weight
    532.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    306°C

    Flash point

    • 291.81 ˚C est.

  • Synonyms

    • Ganoderic Acid G
    • 98665-22-6
    • EZ7U8EY503
    • UNII-EZ7U8EY503
    • (6R)-2-methyl-4-oxo-6-[(3S,5R,7S,10S,12S,13R,14R,17R)-3,7,12-trihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]heptanoic acid
    • (3beta,7beta,12beta)-3,7,12-trihydroxy-11,15,23-trioxolanost-8-en-26-oic acid
    • Lanost-8-en-26-oic acid, 3,7,12-trihydroxy-11,15,23-trioxo-, (3beta,7beta,12beta)-
    • 2-Methyl-4-oxo-6-(3,7,12-trihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta(a)phenanthren-17-yl)heptanoic acid
    • (3.BETA.,7.BETA.,12.BETA.)-3,7,12-TRIHYDROXY-11,15,23-TRIOXOLANOST-8-EN-26-OIC ACID
    • LANOST-8-EN-26-OIC ACID, 3,7,12-TRIHYDROXY-11,15,23-TRIOXO-, (3.BETA.,7.BETA.,12.BETA.)-
    • (6R)-2-methyl-4-oxo-6-((3S,5R,7S,10S,12S,13R,14R,17R)-3,7,12-trihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta(a)phenanthren-17-yl)heptanoic acid
    • RefChem:142461
    • 2-methyl-4-oxo-6-(3,7,12-trihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl)heptanoic acid
    • ganoderate G
    • orb1303402
    • SCHEMBL18274647
    • HY-N2458
    • AKOS040757689
    • EBC-617049
    • (6R)-6-[(1R,3aR,4S,5aR,7S,9aS,11S,11aR)-4,7,11-trihydroxy-3a,6,6,9a,11a-pentamethyl-3,10-dioxo-1H,2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9H,9aH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-4-oxoheptanoic acid
    • DA-63688
    • MS-29851
    • CS-0022686
    • (3|A,7|A,12|A)-3,7,12-Trihydroxy-11,15,23-trioxolanost-8-en-26-oic acid; (6R)-2-methyl-4-oxo-6-((3S,5R,7S,10S,12S,13R,14R,17R)-3,7,12-trihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)heptanoic acid
    • 98665-22-6

  • Applications

    Ganoderic Acid G, CAS 98665-22-6, is a triterpenoid derived from Ganoderma species. In industry, it is primarily encountered in research contexts and Ganoderma-derived preparations; potential applications include: (1) cosmetics/personal care as a bioactive ingredient in skin and hair care formulations (subject to regulatory limits); (2) nutraceuticals/dietary supplements where it may be present in Ganoderma extracts and used as a marker constituent for quality control; (3) pharmaceutical and biomedical research as a pharmacologically active natural product scaffold for lead discovery and mechanistic studies; (4) analytical/quality-control workflows for Ganoderma-derived materials, where it serves as a reference marker in HPLC/LC-MS profiling; (5) natural product chemistry research, including isolation, characterization, and synthetic modification of ganoderic acid scaffolds for library development.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 47.0
    methanol 85.19
    isopropanol 23.09
    water 0.12
    ethyl acetate 6.53
    n-propanol 26.19
    acetone 37.16
    n-butanol 12.49
    acetonitrile 7.63
    DMF 136.75
    toluene 1.8
    isobutanol 10.3
    1,4-dioxane 53.56
    methyl acetate 10.93
    THF 144.14
    2-butanone 17.57
    n-pentanol 8.42
    sec-butanol 7.77
    n-hexane 0.14
    ethylene glycol 18.19
    NMP 74.34
    cyclohexane 0.2
    DMSO 182.58
    n-butyl acetate 4.27
    n-octanol 2.32
    chloroform 13.88
    n-propyl acetate 4.42
    acetic acid 53.62
    dichloromethane 10.28
    cyclohexanone 24.86
    propylene glycol 19.48
    isopropyl acetate 4.1
    DMAc 81.99
    2-ethoxyethanol 44.21
    isopentanol 5.74
    n-heptane 0.08
    ethyl formate 8.87
    1,2-dichloroethane 7.68
    n-hexanol 5.92
    2-methoxyethanol 102.95
    isobutyl acetate 2.31
    tetrachloromethane 1.98
    n-pentyl acetate 5.05
    transcutol 24.6
    n-heptanol 4.26
    ethylbenzene 0.92
    MIBK 4.47
    2-propoxyethanol 45.49
    tert-butanol 10.96
    MTBE 3.42
    2-butoxyethanol 20.96
    propionic acid 12.99
    o-xylene 0.96
    formic acid 38.06
    diethyl ether 6.35
    m-xylene 0.95
    p-xylene 1.16
    chlorobenzene 2.34
    dimethyl carbonate 11.1
    n-octane 0.07
    formamide 43.71
    cyclopentanone 56.14
    2-pentanone 10.05
    anisole 3.89
    cyclopentyl methyl ether 10.33
    gamma-butyrolactone 52.72
    1-methoxy-2-propanol 50.3
    pyridine 23.4
    3-pentanone 6.63
    furfural 30.78
    n-dodecane 0.03
    diethylene glycol 46.68
    diisopropyl ether 0.75
    tert-amyl alcohol 5.17
    acetylacetone 14.8
    n-hexadecane 0.04
    acetophenone 5.01
    methyl propionate 10.07
    isopentyl acetate 3.36
    trichloroethylene 14.11
    n-nonanol 2.44
    cyclohexanol 4.84
    benzyl alcohol 7.94
    2-ethylhexanol 1.47
    isooctanol 2.38
    dipropyl ether 2.22
    1,2-dichlorobenzene 1.81
    ethyl lactate 5.12
    propylene carbonate 12.02
    n-methylformamide 57.91
    2-pentanol 3.39
    n-pentane 0.15
    1-propoxy-2-propanol 17.15
    1-methoxy-2-propyl acetate 9.62
    2-(2-methoxypropoxy) propanol 9.2
    mesitylene 0.49
    ε-caprolactone 18.51
    p-cymene 0.45
    epichlorohydrin 54.12
    1,1,1-trichloroethane 3.74
    2-aminoethanol 33.14
    morpholine-4-carbaldehyde 90.91
    sulfolane 72.04
    2,2,4-trimethylpentane 0.05
    2-methyltetrahydrofuran 21.31
    n-hexyl acetate 5.02
    isooctane 0.04
    2-(2-butoxyethoxy)ethanol 15.65
    sec-butyl acetate 2.01
    tert-butyl acetate 3.78
    decalin 0.09
    glycerin 36.24
    diglyme 28.29
    acrylic acid 17.0
    isopropyl myristate 1.09
    n-butyric acid 12.85
    acetyl acetate 4.91
    di(2-ethylhexyl) phthalate 2.75
    ethyl propionate 3.45
    nitromethane 58.35
    1,2-diethoxyethane 6.53
    benzonitrile 4.37
    trioctyl phosphate 1.92
    1-bromopropane 2.76
    gamma-valerolactone 101.75
    n-decanol 1.28
    triethyl phosphate 1.75
    4-methyl-2-pentanol 1.67
    propionitrile 5.88
    vinylene carbonate 13.17
    1,1,2-trichlorotrifluoroethane 40.47
    DMS 5.8
    cumene 0.56
    2-octanol 1.73
    2-hexanone 6.41
    octyl acetate 2.11
    limonene 0.6
    1,2-dimethoxyethane 45.47
    ethyl orthosilicate 1.64
    tributyl phosphate 1.61
    diacetone alcohol 10.62
    N,N-dimethylaniline 2.87
    acrylonitrile 9.85
    aniline 5.34
    1,3-propanediol 46.79
    bromobenzene 1.63
    dibromomethane 5.71
    1,1,2,2-tetrachloroethane 12.12
    2-methyl-cyclohexyl acetate 2.74
    tetrabutyl urea 3.03
    diisobutyl methanol 0.68
    2-phenylethanol 7.4
    styrene 1.02
    dioctyl adipate 2.56
    dimethyl sulfate 20.14
    ethyl butyrate 2.5
    methyl lactate 14.53
    butyl lactate 6.16
    diethyl carbonate 1.77
    propanediol butyl ether 16.35
    triethyl orthoformate 2.53
    p-tert-butyltoluene 0.43
    methyl 4-tert-butylbenzoate 6.02
    morpholine 70.59
    tert-butylamine 2.36
    n-dodecanol 0.66
    dimethoxymethane 68.53
    ethylene carbonate 10.85
    cyrene 17.42
    2-ethoxyethyl acetate 10.77
    2-ethylhexyl acetate 2.26
    1,2,4-trichlorobenzene 3.05
    4-methylpyridine 12.65
    dibutyl ether 1.14
    2,6-dimethyl-4-heptanol 0.68
    DEF 14.16
    dimethyl isosorbide 15.63
    tetrachloroethylene 8.89
    eugenol 7.98
    triacetin 6.02
    span 80 8.82
    1,4-butanediol 17.14
    1,1-dichloroethane 5.12
    2-methyl-1-pentanol 3.96
    methyl formate 37.25
    2-methyl-1-butanol 5.35
    n-decane 0.09
    butyronitrile 4.95
    3,7-dimethyl-1-octanol 1.28
    1-chlorooctane 0.55
    1-chlorotetradecane 0.14
    n-nonane 0.08
    undecane 0.05
    tert-butylcyclohexane 0.07
    cyclooctane 0.06
    cyclopentanol 13.98
    tetrahydropyran 19.25
    tert-amyl methyl ether 2.28
    2,5,8-trioxanonane 15.76
    1-hexene 0.72
    2-isopropoxyethanol 16.84
    2,2,2-trifluoroethanol 16.39
    methyl butyrate 5.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction