Ganoderic Acid F

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  • Identifiers

    CAS number
    98665-15-7

    Molecular formula
    C32H42O9

    SMILES
    C[C@H](CC(=O)CC(C)C(=O)O)[C@H]1CC(=O)[C@@]2([C@@]1([C@@H](C(=O)C3=C2C(=O)C[C@@H]4[C@@]3(CCC(=O)C4(C)C)C)OC(=O)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 48.53%
    Odorless 41.86%
    Dry 27.12%
    Cedar 24.47%
    Mint 24.16%
    Cooling 21.56%
    Tobacco 21.19%
    Amber 18.84%
    Spicy 18.46%
    Camphoreous 17.97%

     

    Flavor
    Bitter 79.31%
    Odorless 25.89%
    Bland 21.94%
    Cedarleaf 20.73%
    Sweet-like 20.04%
    Ripe apricot 19.79%
    Broom 19.74%
    Parsley 19.71%
    Heather 19.66%
    Fenugreek 19.46%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    3.39 (weak acid)

    Molecular weight
    570.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    294°C

    Flash point

    • 279.03 ˚C est.

  • Synonyms

    • ganoderic acid F
    • 98665-15-7
    • CLQ52DLW7V
    • (12beta)-12-(acetyloxy)-3,7,11,15,23-pentaoxolanost-8-en-26-oic acid
    • (6R)-6-[(5R,10S,12S,13R,14R,17R)-12-acetyloxy-4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,5,6,12,16,17-hexahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
    • DTXSID501316734
    • (6R)-6-((5R,10S,12S,13R,14R,17R)-12-Acetoxy-4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,5,6,12,16,17-hexahydro-1H-cyclopenta(a)phenanthren-17-yl)-2-methyl-4-oxo-heptanoic acid
    • Lanost-8-en-26-oic acid, 12-(acetyloxy)-3,7,11,15,23-pentaoxo-, (12beta)-
    • (6R)-6-((5R,10S,12S,13R,14R,17R)-12-acetyloxy-4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,5,6,12,16,17-hexahydro-1H-cyclopenta(a)phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid
    • RefChem:142460
    • DTXCID401746566
    • UNII-CLQ52DLW7V
    • MFCD09264655
    • C32H42O9
    • Ganoderate F
    • 12-acetoxyganoderic acid F
    • Ganoderic acid F (Standard)
    • CHEMBL453981
    • orb1309642
    • SCHEMBL2159013
    • GTPL13595
    • HY-N6036R
    • CHEBI:142258
    • HY-N6036
    • BDBM50021403
    • AKOS040733227
    • EBC-617076
    • FG74431
    • compound 19 [PMID: 24974349]
    • (6R)-6-[(1R,3aR,5aR,9aS,11S,11aR)-11-(acetyloxy)-3a,6,6,9a,11a-pentamethyl-3,4,7,10-tetraoxo-1H,2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9H,9aH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-4-oxoheptanoic acid
    • DA-53501
    • MS-30306
    • SY409892
    • CS-0032212
    • 12beta-(Acetyloxy)-3,7,11,15,23-pentaoxolanost-8-en-26-oic acid
    • (12.BETA.)-12-(ACETYLOXY)-3,7,11,15,23-PENTAOXOLANOST-8-EN-26-OIC ACID
    • LANOST-8-EN-26-OIC ACID, 12-(ACETYLOXY)-3,7,11,15,23-PENTAOXO-, (12.BETA.)-
    • (6R)-6-((5R,10S,12S,13R,14R,17R)-12-Acetoxy-4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxoheptanoic Acid
    • 98665-15-7

  • Applications

    Ganoderic Acid F (CAS 98665-15-7) is a lanostane-type triterpenoid isolated from Ganoderma lucidum and is often considered as an intermediate and structural scaffold for the synthesis of ganoderic acid derivatives. In research and development, it may be used as an analytical reference standard and as a starting point for preparing derivatives to study structure, physical-chemical properties, and synthetic transformations. Practical applications include: supporting natural product chemistry and precursor synthesis for ganoderic acid derivatives; potentially serving as a bioactive component in cosmetics and personal-care formulations in extract or purified form; potentially appearing as a constituent in functional food/nutraceutical formulations derived from mushroom extracts; and supporting quality control and component identification in analytical systems such as HPLC/GC-MS, while providing a research framework for pharmaceutical and biomaterials development.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 72.27
    methanol 65.77
    isopropanol 67.84
    water 0.09
    ethyl acetate 36.03
    n-propanol 76.82
    acetone 106.01
    n-butanol 51.87
    acetonitrile 30.33
    DMF 255.91
    toluene 13.61
    isobutanol 43.78
    1,4-dioxane 159.14
    methyl acetate 54.43
    THF 367.78
    2-butanone 90.37
    n-pentanol 39.24
    sec-butanol 46.46
    n-hexane 0.7
    ethylene glycol 15.84
    NMP 265.82
    cyclohexane 1.18
    DMSO 267.3
    n-butyl acetate 21.03
    n-octanol 7.93
    chloroform 98.69
    n-propyl acetate 24.77
    acetic acid 135.57
    dichloromethane 71.94
    cyclohexanone 122.72
    propylene glycol 29.46
    isopropyl acetate 23.02
    DMAc 265.92
    2-ethoxyethanol 107.56
    isopentanol 29.86
    n-heptane 0.27
    ethyl formate 35.29
    1,2-dichloroethane 46.41
    n-hexanol 21.8
    2-methoxyethanol 179.82
    isobutyl acetate 13.7
    tetrachloromethane 10.77
    n-pentyl acetate 18.98
    transcutol 74.62
    n-heptanol 12.37
    ethylbenzene 6.05
    MIBK 21.61
    2-propoxyethanol 104.36
    tert-butanol 38.89
    MTBE 19.77
    2-butoxyethanol 51.3
    propionic acid 58.68
    o-xylene 6.58
    formic acid 51.26
    diethyl ether 32.28
    m-xylene 5.07
    p-xylene 7.6
    chlorobenzene 18.19
    dimethyl carbonate 40.32
    n-octane 0.19
    formamide 65.91
    cyclopentanone 190.84
    2-pentanone 52.35
    anisole 21.72
    cyclopentyl methyl ether 48.1
    gamma-butyrolactone 196.09
    1-methoxy-2-propanol 127.56
    pyridine 102.28
    3-pentanone 38.68
    furfural 108.16
    n-dodecane 0.14
    diethylene glycol 71.48
    diisopropyl ether 3.72
    tert-amyl alcohol 31.48
    acetylacetone 54.99
    n-hexadecane 0.17
    acetophenone 25.87
    methyl propionate 48.37
    isopentyl acetate 18.01
    trichloroethylene 92.51
    n-nonanol 8.69
    cyclohexanol 32.35
    benzyl alcohol 36.1
    2-ethylhexanol 7.22
    isooctanol 8.05
    dipropyl ether 9.79
    1,2-dichlorobenzene 13.97
    ethyl lactate 19.31
    propylene carbonate 58.98
    n-methylformamide 105.93
    2-pentanol 21.03
    n-pentane 0.78
    1-propoxy-2-propanol 48.38
    1-methoxy-2-propyl acetate 35.42
    2-(2-methoxypropoxy) propanol 30.71
    mesitylene 2.22
    ε-caprolactone 105.82
    p-cymene 2.16
    epichlorohydrin 199.36
    1,1,1-trichloroethane 32.32
    2-aminoethanol 42.61
    morpholine-4-carbaldehyde 254.04
    sulfolane 243.84
    2,2,4-trimethylpentane 0.33
    2-methyltetrahydrofuran 119.1
    n-hexyl acetate 21.21
    isooctane 0.17
    2-(2-butoxyethoxy)ethanol 45.84
    sec-butyl acetate 13.61
    tert-butyl acetate 17.96
    decalin 0.62
    glycerin 52.02
    diglyme 78.47
    acrylic acid 60.64
    isopropyl myristate 5.32
    n-butyric acid 68.31
    acetyl acetate 27.09
    di(2-ethylhexyl) phthalate 11.15
    ethyl propionate 20.63
    nitromethane 155.15
    1,2-diethoxyethane 24.24
    benzonitrile 22.2
    trioctyl phosphate 7.4
    1-bromopropane 24.32
    gamma-valerolactone 288.22
    n-decanol 5.04
    triethyl phosphate 8.34
    4-methyl-2-pentanol 8.11
    propionitrile 31.53
    vinylene carbonate 58.75
    1,1,2-trichlorotrifluoroethane 124.06
    DMS 22.65
    cumene 3.2
    2-octanol 6.18
    2-hexanone 36.66
    octyl acetate 9.89
    limonene 3.17
    1,2-dimethoxyethane 119.87
    ethyl orthosilicate 7.9
    tributyl phosphate 7.28
    diacetone alcohol 39.33
    N,N-dimethylaniline 14.32
    acrylonitrile 40.58
    aniline 31.9
    1,3-propanediol 81.53
    bromobenzene 14.03
    dibromomethane 44.33
    1,1,2,2-tetrachloroethane 78.07
    2-methyl-cyclohexyl acetate 14.45
    tetrabutyl urea 13.13
    diisobutyl methanol 2.8
    2-phenylethanol 27.97
    styrene 7.69
    dioctyl adipate 12.39
    dimethyl sulfate 73.72
    ethyl butyrate 13.56
    methyl lactate 44.41
    butyl lactate 20.41
    diethyl carbonate 9.67
    propanediol butyl ether 39.11
    triethyl orthoformate 11.72
    p-tert-butyltoluene 2.03
    methyl 4-tert-butylbenzoate 21.16
    morpholine 229.8
    tert-butylamine 10.97
    n-dodecanol 2.9
    dimethoxymethane 137.91
    ethylene carbonate 50.86
    cyrene 60.84
    2-ethoxyethyl acetate 35.45
    2-ethylhexyl acetate 12.91
    1,2,4-trichlorobenzene 25.01
    4-methylpyridine 72.41
    dibutyl ether 5.88
    2,6-dimethyl-4-heptanol 2.8
    DEF 65.91
    dimethyl isosorbide 48.95
    tetrachloroethylene 43.07
    eugenol 24.62
    triacetin 22.8
    span 80 28.08
    1,4-butanediol 33.28
    1,1-dichloroethane 42.0
    2-methyl-1-pentanol 25.06
    methyl formate 73.62
    2-methyl-1-butanol 32.48
    n-decane 0.32
    butyronitrile 27.96
    3,7-dimethyl-1-octanol 5.31
    1-chlorooctane 2.5
    1-chlorotetradecane 0.75
    n-nonane 0.26
    undecane 0.2
    tert-butylcyclohexane 0.42
    cyclooctane 0.25
    cyclopentanol 73.56
    tetrahydropyran 105.45
    tert-amyl methyl ether 14.84
    2,5,8-trioxanonane 48.03
    1-hexene 4.83
    2-isopropoxyethanol 56.05
    2,2,2-trifluoroethanol 49.38
    methyl butyrate 30.07

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction