Ganoderic acid eta

Overview IFRA Request a quote

  • Identifiers

    CAS number
    294674-12-7

    Molecular formula
    C30H44O8

    SMILES
    C[C@H](C[C@@H](/C=C(\C)/C(=O)O)O)[C@H]1CC(=O)[C@@]2([C@@]1([C@@H](C(=O)C3=C2[C@H](C[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)O)C)C

    Safety labels

  • Odor profile

    Fragrance
    Odorless 47.1%
    Woody 47.04%
    Sweet 31.48%
    Mint 29.19%
    Cooling 28.72%
    Dry 25.62%
    Spicy 25.08%
    Balsamic 23.27%
    Camphoreous 23.22%
    Warm 21.75%

     

    Flavor
    Bitter 88.41%
    Odorless 28.86%
    Bland 25.05%
    Sweet-like 22.03%
    Cedarleaf 21.52%
    Parsley 19.58%
    Ripe apricot 19.36%
    Leaves 19.24%
    Heather 19.12%
    Lovage 19.04%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    4.5 (weak acid)

    Molecular weight
    532.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    569°C

    Flash point

    • 295.96 ˚C est.

  • Synonyms

    • Ganoderic acid eta
    • 294674-12-7
    • (E,4S,6R)-4-hydroxy-2-methyl-6-[(3S,5R,7S,10S,12S,13R,14R,17R)-3,7,12-trihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-2-enoic acid
    • (E,4S,6R)-4-hydroxy-2-methyl-6-((3S,5R,7S,10S,12S,13R,14R,17R)-3,7,12-trihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta(a)phenanthren-17-yl)hept-2-enoic acid
    • RefChem:142459
    • Ganoderic acid I.
    • CHEBI:183579
    • DTXSID201316561
    • (23S,24E)-3beta,7beta,12beta,23-Tetrahydroxy-11,15-dioxolanosta-8,24-dien-26-oic acid
    • 294674-12-7

  • Applications

    Ganoderic acid eta (CAS 294674-12-7) is a lanostane-type triterpenoid isolated from Ganoderma lucidum and is used as a reference compound, an intermediate, and a research subject in natural products chemistry. In practical settings, typical applications include: serving as a precursor for the synthesis of related ganoderic and other triterpenoids; evaluated in pharmaceutical discovery as a lead or building block for natural product-based exploration of bioactivity; used in cosmetics and personal care formulations in purified form or as part of extracts with activity; present in nutraceuticals or dietary supplements derived from Ganoderma extracts; and used as an analytical marker for quality control of Ganoderma extracts using HPLC or GC.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 35.14
    methanol 70.62
    isopropanol 15.61
    water 0.11
    ethyl acetate 4.91
    n-propanol 18.44
    acetone 27.08
    n-butanol 8.85
    acetonitrile 5.11
    DMF 98.99
    toluene 1.48
    isobutanol 6.97
    1,4-dioxane 38.27
    methyl acetate 7.91
    THF 110.58
    2-butanone 13.12
    n-pentanol 6.04
    sec-butanol 5.29
    n-hexane 0.13
    ethylene glycol 13.96
    NMP 55.61
    cyclohexane 0.17
    DMSO 143.53
    n-butyl acetate 3.15
    n-octanol 1.85
    chloroform 9.67
    n-propyl acetate 3.09
    acetic acid 38.64
    dichloromethane 7.32
    cyclohexanone 18.13
    propylene glycol 14.03
    isopropyl acetate 3.06
    DMAc 59.7
    2-ethoxyethanol 31.87
    isopentanol 4.01
    n-heptane 0.08
    ethyl formate 6.59
    1,2-dichloroethane 5.59
    n-hexanol 4.6
    2-methoxyethanol 77.72
    isobutyl acetate 1.62
    tetrachloromethane 1.52
    n-pentyl acetate 3.94
    transcutol 17.1
    n-heptanol 3.51
    ethylbenzene 0.72
    MIBK 3.31
    2-propoxyethanol 33.18
    tert-butanol 7.51
    MTBE 2.63
    2-butoxyethanol 15.66
    propionic acid 9.22
    o-xylene 0.78
    formic acid 30.67
    diethyl ether 4.77
    m-xylene 0.81
    p-xylene 0.89
    chlorobenzene 1.71
    dimethyl carbonate 8.54
    n-octane 0.06
    formamide 33.76
    cyclopentanone 41.03
    2-pentanone 7.62
    anisole 2.83
    cyclopentyl methyl ether 8.2
    gamma-butyrolactone 37.0
    1-methoxy-2-propanol 36.52
    pyridine 17.24
    3-pentanone 5.11
    furfural 21.33
    n-dodecane 0.03
    diethylene glycol 34.71
    diisopropyl ether 0.62
    tert-amyl alcohol 3.72
    acetylacetone 11.21
    n-hexadecane 0.04
    acetophenone 3.65
    methyl propionate 7.66
    isopentyl acetate 2.45
    trichloroethylene 10.42
    n-nonanol 1.93
    cyclohexanol 3.54
    benzyl alcohol 5.67
    2-ethylhexanol 1.18
    isooctanol 1.95
    dipropyl ether 1.79
    1,2-dichlorobenzene 1.35
    ethyl lactate 3.65
    propylene carbonate 8.34
    n-methylformamide 42.79
    2-pentanol 2.45
    n-pentane 0.13
    1-propoxy-2-propanol 12.44
    1-methoxy-2-propyl acetate 7.16
    2-(2-methoxypropoxy) propanol 6.83
    mesitylene 0.41
    ε-caprolactone 13.31
    p-cymene 0.38
    epichlorohydrin 39.06
    1,1,1-trichloroethane 2.65
    2-aminoethanol 24.27
    morpholine-4-carbaldehyde 64.87
    sulfolane 52.73
    2,2,4-trimethylpentane 0.05
    2-methyltetrahydrofuran 15.73
    n-hexyl acetate 3.78
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 11.29
    sec-butyl acetate 1.45
    tert-butyl acetate 2.92
    decalin 0.08
    glycerin 27.31
    diglyme 20.42
    acrylic acid 12.78
    isopropyl myristate 0.83
    n-butyric acid 9.03
    acetyl acetate 3.6
    di(2-ethylhexyl) phthalate 2.01
    ethyl propionate 2.47
    nitromethane 41.68
    1,2-diethoxyethane 4.8
    benzonitrile 3.01
    trioctyl phosphate 1.51
    1-bromopropane 2.01
    gamma-valerolactone 74.55
    n-decanol 1.02
    triethyl phosphate 1.34
    4-methyl-2-pentanol 1.3
    propionitrile 4.14
    vinylene carbonate 9.15
    1,1,2-trichlorotrifluoroethane 29.96
    DMS 4.22
    cumene 0.45
    2-octanol 1.4
    2-hexanone 4.7
    octyl acetate 1.64
    limonene 0.5
    1,2-dimethoxyethane 32.59
    ethyl orthosilicate 1.26
    tributyl phosphate 1.19
    diacetone alcohol 8.08
    N,N-dimethylaniline 2.15
    acrylonitrile 7.03
    aniline 3.98
    1,3-propanediol 34.13
    bromobenzene 1.18
    dibromomethane 4.15
    1,1,2,2-tetrachloroethane 8.71
    2-methyl-cyclohexyl acetate 2.03
    tetrabutyl urea 2.25
    diisobutyl methanol 0.54
    2-phenylethanol 5.47
    styrene 0.77
    dioctyl adipate 1.87
    dimethyl sulfate 15.12
    ethyl butyrate 1.86
    methyl lactate 10.99
    butyl lactate 4.59
    diethyl carbonate 1.29
    propanediol butyl ether 11.87
    triethyl orthoformate 1.94
    p-tert-butyltoluene 0.36
    methyl 4-tert-butylbenzoate 4.63
    morpholine 50.74
    tert-butylamine 1.68
    n-dodecanol 0.54
    dimethoxymethane 51.09
    ethylene carbonate 7.41
    cyrene 12.69
    2-ethoxyethyl acetate 8.16
    2-ethylhexyl acetate 1.7
    1,2,4-trichlorobenzene 2.18
    4-methylpyridine 8.79
    dibutyl ether 0.88
    2,6-dimethyl-4-heptanol 0.54
    DEF 10.54
    dimethyl isosorbide 11.64
    tetrachloroethylene 6.93
    eugenol 6.03
    triacetin 4.38
    span 80 6.58
    1,4-butanediol 12.16
    1,1-dichloroethane 3.59
    2-methyl-1-pentanol 2.85
    methyl formate 27.98
    2-methyl-1-butanol 3.79
    n-decane 0.08
    butyronitrile 3.39
    3,7-dimethyl-1-octanol 0.97
    1-chlorooctane 0.46
    1-chlorotetradecane 0.12
    n-nonane 0.07
    undecane 0.05
    tert-butylcyclohexane 0.06
    cyclooctane 0.06
    cyclopentanol 10.1
    tetrahydropyran 13.9
    tert-amyl methyl ether 1.78
    2,5,8-trioxanonane 11.62
    1-hexene 0.58
    2-isopropoxyethanol 11.81
    2,2,2-trifluoroethanol 11.45
    methyl butyrate 3.68

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction