Ganoderic acid epsilon

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  • Identifiers

    CAS number
    294674-05-8

    Molecular formula
    C30H44O7

    SMILES
    C[C@H](C[C@@H](/C=C(\C)/C(=O)O)O)[C@H]1CC(=O)[C@@]2([C@@]1(CC(=O)C3=C2[C@H](C[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 57.07%
    Odorless 41.1%
    Dry 30.12%
    Mint 28.83%
    Cedar 28.31%
    Amber 27.66%
    Cooling 26.76%
    Sweet 26.49%
    Spicy 26.33%
    Balsamic 25.39%

     

    Flavor
    Bitter 87.12%
    Odorless 26.98%
    Bland 23.8%
    Cedarleaf 22.08%
    Sweet-like 21.13%
    Parsley 19.96%
    Ripe apricot 19.77%
    Heather 19.69%
    Broom 19.52%
    Leaves 19.44%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    4.73 (weak acid)

    Molecular weight
    516.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    491°C

    Flash point

    • 293.12 ˚C est.

  • Synonyms

    • Ganoderic acid epsilon
    • (E,4S,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-Dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-4-hydroxy-2-methylhept-2-enoic acid
    • (E,4S,6R)-6-((3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta(a)phenanthren-17-yl)-4-hydroxy-2-methylhept-2-enoic acid
    • RefChem:142458
    • 294674-05-8
    • Ganoderic acid |A
    • Lanosta-8,24-dien-26-oic acid, 3,7,23-trihydroxy-11,15-dioxo-, (3beta,7beta,23S,24E)-
    • Ganoderic acid ??
    • (+)-Ganoderic acid Imicro
    • orb1690632
    • SCHEMBL29934570
    • CHEBI:168657
    • DTXSID701315063
    • HY-N9350
    • AKOS040758023
    • MS-29595
    • CS-0159498
    • G18170
    • (23S,24E)-3beta,7beta,23-Trihydroxy-11,15-dioxolanosta-8,24-dien-26-oic acid
    • Lanosta-8,24-dien-26-oic acid, 3,7,23-trihydroxy-11,15-dioxo-, (3|A,7|A,23S,24E)-
    • (E,4S,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-4-hydroxy-2-methyl-hept-2-enoic acid
    • 294674-05-8

  • Applications

    Ganoderic acid epsilon, CAS 294674-05-8, is a triterpenoid derived from Ganoderma species and is primarily used in research as a reference compound and as an intermediate for the synthesis of related triterpenoids. In industry, it commonly serves as a chromatographic analytical reference and as a precursor for the synthesis of ganoderic derivatives. Represented application areas include cosmetics/personal care formulation research, pharmaceutical lead discovery research, and phytochemical evaluation for functional nutrition products in a research context. It may also be used as an analytical standard for profiling Ganoderma-derived triterpenoids, with use subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 31.22
    methanol 57.39
    isopropanol 13.05
    water 0.05
    ethyl acetate 3.56
    n-propanol 18.13
    acetone 18.06
    n-butanol 7.92
    acetonitrile 4.06
    DMF 101.29
    toluene 1.17
    isobutanol 6.31
    1,4-dioxane 31.91
    methyl acetate 5.85
    THF 101.07
    2-butanone 10.49
    n-pentanol 5.41
    sec-butanol 4.26
    n-hexane 0.09
    ethylene glycol 8.17
    NMP 49.02
    cyclohexane 0.1
    DMSO 100.87
    n-butyl acetate 2.66
    n-octanol 1.36
    chloroform 11.37
    n-propyl acetate 2.7
    acetic acid 25.23
    dichloromethane 7.56
    cyclohexanone 14.89
    propylene glycol 10.51
    isopropyl acetate 2.3
    DMAc 54.24
    2-ethoxyethanol 28.19
    isopentanol 3.52
    n-heptane 0.05
    ethyl formate 4.95
    1,2-dichloroethane 4.79
    n-hexanol 4.03
    2-methoxyethanol 67.61
    isobutyl acetate 1.55
    tetrachloromethane 1.26
    n-pentyl acetate 3.15
    transcutol 15.11
    n-heptanol 2.7
    ethylbenzene 0.61
    MIBK 2.84
    2-propoxyethanol 33.99
    tert-butanol 5.6
    MTBE 1.84
    2-butoxyethanol 14.45
    propionic acid 7.02
    o-xylene 0.61
    formic acid 20.44
    diethyl ether 3.57
    m-xylene 0.66
    p-xylene 0.77
    chlorobenzene 1.55
    dimethyl carbonate 6.16
    n-octane 0.03
    formamide 23.99
    cyclopentanone 35.93
    2-pentanone 5.86
    anisole 2.55
    cyclopentyl methyl ether 6.43
    gamma-butyrolactone 31.99
    1-methoxy-2-propanol 33.92
    pyridine 16.09
    3-pentanone 3.99
    furfural 18.86
    n-dodecane 0.02
    diethylene glycol 29.91
    diisopropyl ether 0.42
    tert-amyl alcohol 2.77
    acetylacetone 8.17
    n-hexadecane 0.02
    acetophenone 3.39
    methyl propionate 6.05
    isopentyl acetate 2.26
    trichloroethylene 10.27
    n-nonanol 1.42
    cyclohexanol 2.61
    benzyl alcohol 5.37
    2-ethylhexanol 0.99
    isooctanol 1.61
    dipropyl ether 1.44
    1,2-dichlorobenzene 1.29
    ethyl lactate 3.14
    propylene carbonate 6.92
    n-methylformamide 38.17
    2-pentanol 1.95
    n-pentane 0.08
    1-propoxy-2-propanol 12.21
    1-methoxy-2-propyl acetate 6.37
    2-(2-methoxypropoxy) propanol 6.1
    mesitylene 0.33
    ε-caprolactone 10.68
    p-cymene 0.31
    epichlorohydrin 36.31
    1,1,1-trichloroethane 2.4
    2-aminoethanol 20.8
    morpholine-4-carbaldehyde 59.07
    sulfolane 42.65
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 13.22
    n-hexyl acetate 3.13
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 9.89
    sec-butyl acetate 1.26
    tert-butyl acetate 2.26
    decalin 0.05
    glycerin 19.46
    diglyme 18.3
    acrylic acid 9.11
    isopropyl myristate 0.62
    n-butyric acid 7.35
    acetyl acetate 2.58
    di(2-ethylhexyl) phthalate 1.84
    ethyl propionate 2.09
    nitromethane 30.5
    1,2-diethoxyethane 3.75
    benzonitrile 2.99
    trioctyl phosphate 1.2
    1-bromopropane 1.77
    gamma-valerolactone 64.83
    n-decanol 0.72
    triethyl phosphate 1.16
    4-methyl-2-pentanol 1.05
    propionitrile 3.74
    vinylene carbonate 8.0
    1,1,2-trichlorotrifluoroethane 25.65
    DMS 3.35
    cumene 0.38
    2-octanol 1.02
    2-hexanone 4.23
    octyl acetate 1.22
    limonene 0.39
    1,2-dimethoxyethane 29.95
    ethyl orthosilicate 1.09
    tributyl phosphate 0.99
    diacetone alcohol 6.48
    N,N-dimethylaniline 1.9
    acrylonitrile 6.34
    aniline 3.45
    1,3-propanediol 29.03
    bromobenzene 1.13
    dibromomethane 4.02
    1,1,2,2-tetrachloroethane 8.46
    2-methyl-cyclohexyl acetate 1.87
    tetrabutyl urea 1.87
    diisobutyl methanol 0.44
    2-phenylethanol 5.24
    styrene 0.67
    dioctyl adipate 1.56
    dimethyl sulfate 11.68
    ethyl butyrate 1.59
    methyl lactate 8.6
    butyl lactate 4.0
    diethyl carbonate 1.11
    propanediol butyl ether 10.47
    triethyl orthoformate 1.69
    p-tert-butyltoluene 0.28
    methyl 4-tert-butylbenzoate 4.18
    morpholine 47.09
    tert-butylamine 1.2
    n-dodecanol 0.37
    dimethoxymethane 47.49
    ethylene carbonate 6.12
    cyrene 11.86
    2-ethoxyethyl acetate 6.78
    2-ethylhexyl acetate 1.54
    1,2,4-trichlorobenzene 2.11
    4-methylpyridine 8.43
    dibutyl ether 0.66
    2,6-dimethyl-4-heptanol 0.44
    DEF 8.37
    dimethyl isosorbide 10.9
    tetrachloroethylene 6.26
    eugenol 5.73
    triacetin 3.74
    span 80 5.65
    1,4-butanediol 9.87
    1,1-dichloroethane 3.25
    2-methyl-1-pentanol 2.54
    methyl formate 21.4
    2-methyl-1-butanol 3.3
    n-decane 0.05
    butyronitrile 3.07
    3,7-dimethyl-1-octanol 0.79
    1-chlorooctane 0.32
    1-chlorotetradecane 0.08
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.05
    cyclooctane 0.03
    cyclopentanol 8.07
    tetrahydropyran 11.45
    tert-amyl methyl ether 1.29
    2,5,8-trioxanonane 10.19
    1-hexene 0.46
    2-isopropoxyethanol 10.23
    2,2,2-trifluoroethanol 7.48
    methyl butyrate 3.13

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction