Ganoderic Acid B

Overview IFRA Request a quote

  • Identifiers

    CAS number
    81907-61-1

    Molecular formula
    C30H44O7

    SMILES
    C[C@H](CC(=O)C[C@@H](C)C(=O)O)[C@H]1CC(=O)[C@@]2([C@@]1(CC(=O)C3=C2[C@H](C[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 59.97%
    Odorless 41.17%
    Dry 30.49%
    Cedar 29.97%
    Amber 28.2%
    Cooling 27.88%
    Mint 27.41%
    Spicy 25.64%
    Camphoreous 22.14%
    Warm 21.76%

     

    Flavor
    Bitter 85.26%
    Odorless 26.16%
    Bland 23.83%
    Cedarleaf 22.1%
    Sweet-like 21.21%
    Ripe apricot 20.0%
    Parsley 19.92%
    Heather 19.75%
    Red fruit 19.7%
    Leaves 19.56%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    4.55 (weak acid)

    Molecular weight
    516.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    258°C

    Flash point

    • 288.43 ˚C est.

  • Synonyms

    • Ganoderic acid B
    • 81907-61-1
    • AV74TFJ3IS
    • DTXSID20903983
    • RefChem:37482
    • DTXCID701331918
    • (25R)-11,15,23-trioxo-3beta,7beta-dihydroxy-lanost-8-ene-26-oic acid
    • UNII-AV74TFJ3IS
    • (2R,6R)-6-((3S,5R,7S,10S,13R,14R,17R)-3,7-Dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid
    • MFCD09752803
    • (2r,6r)-6-[(3s,5r,7s,10s,13r,14r,17r)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxo-heptanoic acid
    • (2R,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
    • Lanost-8-en-26-oic acid, 3,7-dihydroxy-3,11,23-trioxo-, (7beta,15alpha,25R)-
    • Ganoderic acid B (Standard)
    • GANODERIC ACID B [MI]
    • orb1297578
    • SCHEMBL28713293
    • HY-N2006R
    • CHEBI:168663
    • HY-N2006
    • EX-A10720
    • MSK000861
    • AKOS027338661
    • EBC-515413
    • FG74113
    • (2R,6R)-6-[(1R,3aR,4S,5aR,7S,9aS,11aR)-4,7-dihydroxy-3a,6,6,9a,11a-pentamethyl-3,10-dioxo-1H,2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9H,9aH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-4-oxoheptanoic acid
    • AC-34452
    • DA-53498
    • MS-29597
    • CS-0018326
    • 907G611
    • Q27274134
    • (25R)-3beta,7beta-Dihydroxy-11,15,23-trioxolanost-8-en-26-oic acid
    • GANODERIC ACID B (CONSTITUENT OF GANODERMA LUCIDUM FRUITING BODY) [DSC]
    • Lanost-8-en-26-oic acid, 3,7-dihydroxy-3,11,23-trioxo-, (7.beta.,15.alpha.,25R)-
    • Ganoderic acid BLanost-8-en-26-oic acid, 3,7-dihydroxy-3,11,23-trioxo-, (7beta,15alpha,25R)-
    • LANOST-8-EN-26-OIC ACID, 3,7-DIHYDROXY-11,15,23-TRIOXO-, (3.BETA.,7.BETA.,25R)-
    • 81907-61-1

  • Applications

    Ganoderic Acid B (CAS 81907-61-1) is a triterpenoid isolated from Ganoderma lucidum. In industry, it is primarily used as an analytical reference material and a research ingredient for natural product studies, while its potential as a lead compound for natural product–derived pharmaceutical development is being explored. Real-world applications focus on: supporting lead- and SAR-oriented research and biological activity profiling of the ganoderic acids; being considered as a bioactive constituent in cosmetic/personal care formulations based on Ganoderma extracts; being evaluated for inclusion in nutraceutical or functional food ingredients derived from mushroom extracts; and serving as a reference standard in LC-MS/NMR analysis of natural products. These uses are typically in research and development or analytical contexts and are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 41.36
    methanol 65.67
    isopropanol 19.63
    water 0.05
    ethyl acetate 5.15
    n-propanol 26.6
    acetone 26.04
    n-butanol 11.85
    acetonitrile 6.5
    DMF 142.25
    toluene 1.54
    isobutanol 9.65
    1,4-dioxane 45.0
    methyl acetate 8.62
    THF 129.93
    2-butanone 15.37
    n-pentanol 7.87
    sec-butanol 6.38
    n-hexane 0.1
    ethylene glycol 10.65
    NMP 69.2
    cyclohexane 0.12
    DMSO 123.52
    n-butyl acetate 3.82
    n-octanol 1.71
    chloroform 17.67
    n-propyl acetate 4.03
    acetic acid 35.73
    dichloromethane 11.45
    cyclohexanone 21.22
    propylene glycol 14.34
    isopropyl acetate 3.31
    DMAc 77.53
    2-ethoxyethanol 38.73
    isopentanol 5.14
    n-heptane 0.05
    ethyl formate 7.09
    1,2-dichloroethane 6.97
    n-hexanol 5.21
    2-methoxyethanol 88.43
    isobutyl acetate 2.33
    tetrachloromethane 1.71
    n-pentyl acetate 4.17
    transcutol 21.77
    n-heptanol 3.28
    ethylbenzene 0.82
    MIBK 3.94
    2-propoxyethanol 46.43
    tert-butanol 8.17
    MTBE 2.49
    2-butoxyethanol 19.09
    propionic acid 10.34
    o-xylene 0.78
    formic acid 24.99
    diethyl ether 5.07
    m-xylene 0.82
    p-xylene 1.08
    chlorobenzene 2.35
    dimethyl carbonate 8.48
    n-octane 0.04
    formamide 31.25
    cyclopentanone 50.81
    2-pentanone 8.27
    anisole 3.73
    cyclopentyl methyl ether 8.6
    gamma-butyrolactone 48.28
    1-methoxy-2-propanol 46.94
    pyridine 23.44
    3-pentanone 5.45
    furfural 28.52
    n-dodecane 0.02
    diethylene glycol 39.62
    diisopropyl ether 0.53
    tert-amyl alcohol 3.83
    acetylacetone 11.33
    n-hexadecane 0.02
    acetophenone 4.93
    methyl propionate 8.67
    isopentyl acetate 3.21
    trichloroethylene 15.43
    n-nonanol 1.79
    cyclohexanol 3.65
    benzyl alcohol 7.82
    2-ethylhexanol 1.26
    isooctanol 1.96
    dipropyl ether 1.84
    1,2-dichlorobenzene 1.95
    ethyl lactate 4.57
    propylene carbonate 10.82
    n-methylformamide 54.03
    2-pentanol 2.78
    n-pentane 0.09
    1-propoxy-2-propanol 16.85
    1-methoxy-2-propyl acetate 9.04
    2-(2-methoxypropoxy) propanol 8.51
    mesitylene 0.41
    ε-caprolactone 16.02
    p-cymene 0.38
    epichlorohydrin 52.36
    1,1,1-trichloroethane 3.66
    2-aminoethanol 27.94
    morpholine-4-carbaldehyde 85.21
    sulfolane 59.13
    2,2,4-trimethylpentane 0.04
    2-methyltetrahydrofuran 18.58
    n-hexyl acetate 4.26
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 13.66
    sec-butyl acetate 1.86
    tert-butyl acetate 3.04
    decalin 0.07
    glycerin 25.56
    diglyme 25.62
    acrylic acid 12.81
    isopropyl myristate 0.84
    n-butyric acid 11.11
    acetyl acetate 3.74
    di(2-ethylhexyl) phthalate 2.61
    ethyl propionate 3.1
    nitromethane 44.3
    1,2-diethoxyethane 5.21
    benzonitrile 4.58
    trioctyl phosphate 1.57
    1-bromopropane 2.51
    gamma-valerolactone 94.28
    n-decanol 0.9
    triethyl phosphate 1.59
    4-methyl-2-pentanol 1.4
    propionitrile 5.84
    vinylene carbonate 12.21
    1,1,2-trichlorotrifluoroethane 35.78
    DMS 4.84
    cumene 0.5
    2-octanol 1.25
    2-hexanone 6.05
    octyl acetate 1.63
    limonene 0.48
    1,2-dimethoxyethane 42.04
    ethyl orthosilicate 1.46
    tributyl phosphate 1.37
    diacetone alcohol 8.88
    N,N-dimethylaniline 2.62
    acrylonitrile 9.73
    aniline 4.88
    1,3-propanediol 39.78
    bromobenzene 1.72
    dibromomethane 5.94
    1,1,2,2-tetrachloroethane 12.84
    2-methyl-cyclohexyl acetate 2.64
    tetrabutyl urea 2.59
    diisobutyl methanol 0.57
    2-phenylethanol 7.26
    styrene 0.94
    dioctyl adipate 2.23
    dimethyl sulfate 16.09
    ethyl butyrate 2.28
    methyl lactate 12.0
    butyl lactate 5.64
    diethyl carbonate 1.6
    propanediol butyl ether 14.25
    triethyl orthoformate 2.27
    p-tert-butyltoluene 0.35
    methyl 4-tert-butylbenzoate 5.63
    morpholine 66.79
    tert-butylamine 1.73
    n-dodecanol 0.45
    dimethoxymethane 63.79
    ethylene carbonate 9.41
    cyrene 16.57
    2-ethoxyethyl acetate 9.16
    2-ethylhexyl acetate 2.17
    1,2,4-trichlorobenzene 3.25
    4-methylpyridine 12.74
    dibutyl ether 0.88
    2,6-dimethyl-4-heptanol 0.57
    DEF 12.01
    dimethyl isosorbide 15.0
    tetrachloroethylene 8.45
    eugenol 7.81
    triacetin 5.39
    span 80 7.56
    1,4-butanediol 14.0
    1,1-dichloroethane 5.08
    2-methyl-1-pentanol 3.56
    methyl formate 29.5
    2-methyl-1-butanol 4.89
    n-decane 0.05
    butyronitrile 4.94
    3,7-dimethyl-1-octanol 1.02
    1-chlorooctane 0.39
    1-chlorotetradecane 0.09
    n-nonane 0.05
    undecane 0.03
    tert-butylcyclohexane 0.06
    cyclooctane 0.04
    cyclopentanol 11.65
    tetrahydropyran 16.74
    tert-amyl methyl ether 1.72
    2,5,8-trioxanonane 14.2
    1-hexene 0.6
    2-isopropoxyethanol 14.93
    2,2,2-trifluoroethanol 11.32
    methyl butyrate 4.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction