Ganoderic Acid A

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  • Identifiers

    CAS number
    81907-62-2

    Molecular formula
    C30H44O7

    SMILES
    C[C@H](CC(=O)C[C@@H](C)C(=O)O)[C@H]1C[C@@H]([C@@]2([C@@]1(CC(=O)C3=C2[C@H](C[C@@H]4[C@@]3(CCC(=O)C4(C)C)C)O)C)C)O

    Safety labels

  • Odor profile

    Fragrance
    Woody 58.78%
    Odorless 43.14%
    Dry 29.69%
    Cedar 29.05%
    Cooling 28.64%
    Mint 27.68%
    Amber 27.67%
    Spicy 25.42%
    Camphoreous 22.33%
    Balsamic 22.09%

     

    Flavor
    Bitter 85.35%
    Odorless 25.99%
    Bland 23.88%
    Cedarleaf 22.26%
    Sweet-like 21.15%
    Ripe apricot 20.01%
    Parsley 19.86%
    Red fruit 19.68%
    Leaves 19.61%
    Heather 19.57%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    4.61 (weak acid)

    Molecular weight
    516.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    328°C

    Flash point

    • 290.63 ˚C est.

  • Synonyms

    • Ganoderic acid A
    • 81907-62-2
    • 548G37DF65
    • (2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
    • DTXSID80903984
    • Lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7beta,15alpha,25R)-
    • (2R,6R)-6-((5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta(a)phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid
    • RefChem:37018
    • DTXCID401331919
    • (25R)-3,11,23-trioxo-7beta,15alpha-dihydroxy-lanost-8-ene-26-oic acid
    • Ganoderic-acid-A
    • C30H44O7
    • MFCD26131275
    • (2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxo-heptanoic acid
    • Lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7.beta.,15.alpha.,25R)-
    • CHEMBL602899
    • UNII-548G37DF65
    • (7ss,15a,25R)-7,15-Dihydroxy-3,11,23-trioxo-lanost-8-en-26-oic Acid; Ganoderic acid A
    • Ganoderic acid A CRS
    • Ganoderic acid A (Standard)
    • GANODERIC ACID A [MI]
    • SCHEMBL26959617
    • HY-N1447R
    • CHEBI:168262
    • DYOKDAQBNHPJFD-JNTBEZBXSA-N
    • GANODERIC ACID A [USP-RS]
    • HY-N1447
    • MSK000860
    • CS-5856
    • EBC-509179
    • FG63152
    • (2R,6R)-6-[(1R,3S,3aR,4S,5aR,9aS,11aR)-3,4-dihydroxy-3a,6,6,9a,11a-pentamethyl-7,10-dioxo-1H,2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9H,9aH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-4-oxoheptanoic acid
    • Q3604527
    • (25R)-7beta,15alpha-Dihydroxy-3,11,23-trioxolanost-8-en-26-oic acid
    • GANODERIC ACID A (CONSTITUENT OF GANODERMA LUCIDUM FRUITING BODY) [DSC]
    • Lanost-8-en-26-oic acid\, 7\,15-dihydroxy-3\,11\,23-trioxo-\, (7beta\,15alpha\,25R)-
    • 81907-62-2

  • Applications

    Ganoderic Acid A (CAS 81907-62-2) is a natural lanostane-type triterpenoid isolated from Ganoderma lucidum and is primarily handled as a research chemical and reference standard in industrial workflows; in cosmetics and personal care, it is explored as a bioactive ingredient to support formulation development; in pharmaceutical research, it is studied as a lead structure or scaffold for the discovery and development of triterpenoid derivatives; in chemical synthesis, it can serve as an intermediate for making more complex ganoderic derivatives; in analytical and quality-control workflows, it is used as a reference standard for analytical methods and the characterization of Ganoderma extracts; in agricultural research, it is considered in bioactivity screening as a potential candidate for crop-protection studies.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 30.79
    methanol 55.01
    isopropanol 13.42
    water 0.06
    ethyl acetate 3.65
    n-propanol 18.94
    acetone 19.73
    n-butanol 8.04
    acetonitrile 5.21
    DMF 114.7
    toluene 1.1
    isobutanol 6.64
    1,4-dioxane 33.25
    methyl acetate 6.32
    THF 90.21
    2-butanone 10.79
    n-pentanol 5.34
    sec-butanol 4.2
    n-hexane 0.07
    ethylene glycol 9.22
    NMP 53.81
    cyclohexane 0.08
    DMSO 100.68
    n-butyl acetate 2.71
    n-octanol 1.28
    chloroform 12.94
    n-propyl acetate 2.92
    acetic acid 27.61
    dichloromethane 8.64
    cyclohexanone 15.34
    propylene glycol 10.98
    isopropyl acetate 2.33
    DMAc 59.21
    2-ethoxyethanol 29.74
    isopentanol 3.48
    n-heptane 0.03
    ethyl formate 5.36
    1,2-dichloroethane 5.09
    n-hexanol 3.66
    2-methoxyethanol 69.65
    isobutyl acetate 1.67
    tetrachloromethane 1.27
    n-pentyl acetate 3.16
    transcutol 16.71
    n-heptanol 2.46
    ethylbenzene 0.59
    MIBK 2.82
    2-propoxyethanol 35.66
    tert-butanol 5.68
    MTBE 1.66
    2-butoxyethanol 14.91
    propionic acid 7.78
    o-xylene 0.56
    formic acid 21.89
    diethyl ether 3.49
    m-xylene 0.59
    p-xylene 0.8
    chlorobenzene 1.7
    dimethyl carbonate 6.49
    n-octane 0.03
    formamide 27.3
    cyclopentanone 37.44
    2-pentanone 5.77
    anisole 2.76
    cyclopentyl methyl ether 5.78
    gamma-butyrolactone 36.15
    1-methoxy-2-propanol 34.1
    pyridine 17.74
    3-pentanone 3.87
    furfural 22.72
    n-dodecane 0.02
    diethylene glycol 32.11
    diisopropyl ether 0.36
    tert-amyl alcohol 2.61
    acetylacetone 8.53
    n-hexadecane 0.02
    acetophenone 3.76
    methyl propionate 6.25
    isopentyl acetate 2.27
    trichloroethylene 11.46
    n-nonanol 1.34
    cyclohexanol 2.44
    benzyl alcohol 5.8
    2-ethylhexanol 0.89
    isooctanol 1.46
    dipropyl ether 1.3
    1,2-dichlorobenzene 1.45
    ethyl lactate 3.47
    propylene carbonate 8.06
    n-methylformamide 44.68
    2-pentanol 1.83
    n-pentane 0.06
    1-propoxy-2-propanol 12.64
    1-methoxy-2-propyl acetate 6.63
    2-(2-methoxypropoxy) propanol 6.53
    mesitylene 0.3
    ε-caprolactone 11.4
    p-cymene 0.27
    epichlorohydrin 38.27
    1,1,1-trichloroethane 2.51
    2-aminoethanol 22.12
    morpholine-4-carbaldehyde 67.12
    sulfolane 45.9
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 12.41
    n-hexyl acetate 3.22
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 10.31
    sec-butyl acetate 1.31
    tert-butyl acetate 2.2
    decalin 0.05
    glycerin 20.75
    diglyme 20.01
    acrylic acid 10.04
    isopropyl myristate 0.61
    n-butyric acid 7.89
    acetyl acetate 2.85
    di(2-ethylhexyl) phthalate 2.03
    ethyl propionate 2.28
    nitromethane 36.63
    1,2-diethoxyethane 3.86
    benzonitrile 3.48
    trioctyl phosphate 1.17
    1-bromopropane 1.71
    gamma-valerolactone 72.79
    n-decanol 0.67
    triethyl phosphate 1.19
    4-methyl-2-pentanol 0.96
    propionitrile 4.4
    vinylene carbonate 9.33
    1,1,2-trichlorotrifluoroethane 29.07
    DMS 3.75
    cumene 0.36
    2-octanol 0.93
    2-hexanone 4.3
    octyl acetate 1.19
    limonene 0.34
    1,2-dimethoxyethane 31.98
    ethyl orthosilicate 1.09
    tributyl phosphate 1.02
    diacetone alcohol 6.58
    N,N-dimethylaniline 1.93
    acrylonitrile 7.71
    aniline 3.46
    1,3-propanediol 30.43
    bromobenzene 1.23
    dibromomethane 4.29
    1,1,2,2-tetrachloroethane 9.26
    2-methyl-cyclohexyl acetate 1.96
    tetrabutyl urea 1.96
    diisobutyl methanol 0.41
    2-phenylethanol 5.43
    styrene 0.66
    dioctyl adipate 1.65
    dimethyl sulfate 12.59
    ethyl butyrate 1.67
    methyl lactate 9.12
    butyl lactate 4.35
    diethyl carbonate 1.17
    propanediol butyl ether 11.1
    triethyl orthoformate 1.69
    p-tert-butyltoluene 0.25
    methyl 4-tert-butylbenzoate 4.45
    morpholine 47.99
    tert-butylamine 1.16
    n-dodecanol 0.33
    dimethoxymethane 48.86
    ethylene carbonate 7.01
    cyrene 12.96
    2-ethoxyethyl acetate 7.17
    2-ethylhexyl acetate 1.55
    1,2,4-trichlorobenzene 2.41
    4-methylpyridine 9.35
    dibutyl ether 0.65
    2,6-dimethyl-4-heptanol 0.41
    DEF 8.73
    dimethyl isosorbide 11.72
    tetrachloroethylene 6.37
    eugenol 6.21
    triacetin 4.32
    span 80 5.79
    1,4-butanediol 10.75
    1,1-dichloroethane 3.52
    2-methyl-1-pentanol 2.43
    methyl formate 24.08
    2-methyl-1-butanol 3.3
    n-decane 0.04
    butyronitrile 3.55
    3,7-dimethyl-1-octanol 0.75
    1-chlorooctane 0.29
    1-chlorotetradecane 0.07
    n-nonane 0.03
    undecane 0.02
    tert-butylcyclohexane 0.04
    cyclooctane 0.03
    cyclopentanol 7.8
    tetrahydropyran 11.2
    tert-amyl methyl ether 1.16
    2,5,8-trioxanonane 11.02
    1-hexene 0.4
    2-isopropoxyethanol 11.01
    2,2,2-trifluoroethanol 9.32
    methyl butyrate 3.34

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction