Ganoderenic Acid A

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  • Identifiers

    CAS number
    100665-40-5

    Molecular formula
    C30H42O7

    SMILES
    CC(CC(=O)/C=C(\C)/[C@H]1C[C@@H]([C@@]2([C@@]1(CC(=O)C3=C2[C@H](C[C@@H]4[C@@]3(CCC(=O)C4(C)C)C)O)C)C)O)C(=O)O

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  • Odor profile

    Fragrance
    Woody 59.18%
    Odorless 35.01%
    Dry 31.58%
    Cedar 29.24%
    Mint 29.1%
    Amber 26.24%
    Spicy 25.43%
    Camphoreous 24.97%
    Sweet 24.84%
    Tobacco 24.79%

     

    Flavor
    Bitter 84.13%
    Odorless 25.62%
    Bland 22.39%
    Cedarleaf 21.7%
    Sweet-like 20.57%
    Ripe apricot 19.95%
    Parsley 19.87%
    Leaves 19.78%
    Red fruit 19.67%
    Heather 19.67%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    4.43 (weak acid)

    Molecular weight
    514.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    429°C

    Flash point

    • 290.13 ˚C est.

  • Synonyms

    • Ganoderenic Acid A
    • 100665-40-5
    • DTXSID301316083
    • RefChem:922075
    • DTXCID401745956
    • (E)-6-((5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta(a)phenanthren-17-yl)-2-methyl-4-oxohept-5-enoic acid
    • (Z)-6-((5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta(a)phenanthren-17-yl)-2-methyl-4-oxohept-5-enoic acid
    • CHEMBL1922171
    • SCHEMBL29369725
    • BDBM50359036
    • 907G622
    • 100665-40-5

  • Applications

    Ganoderenic Acid A (CAS 100665-40-5) is a lanostane-type triterpenoid isolated from Ganoderma lucidum. In practical terms, it is commonly used as a bioactive natural product lead in pharmaceutical R&D, as an analytical reference standard for quality control of Ganoderma extracts and related formulations, and as an intermediate or starting point in the synthesis of related lanostane-type triterpenoids. It is also evaluated in cosmetic and personal care research as a potential bioactive ingredient, and may feature in nutraceutical or functional foods studies, with use governed by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 23.97
    methanol 42.01
    isopropanol 10.6
    water 0.04
    ethyl acetate 3.1
    n-propanol 15.82
    acetone 16.16
    n-butanol 6.73
    acetonitrile 4.66
    DMF 100.51
    toluene 0.96
    isobutanol 5.63
    1,4-dioxane 28.17
    methyl acetate 5.69
    THF 74.31
    2-butanone 9.69
    n-pentanol 4.5
    sec-butanol 3.58
    n-hexane 0.06
    ethylene glycol 6.84
    NMP 46.81
    cyclohexane 0.07
    DMSO 83.46
    n-butyl acetate 2.27
    n-octanol 1.11
    chloroform 12.64
    n-propyl acetate 2.55
    acetic acid 21.36
    dichloromethane 8.31
    cyclohexanone 13.18
    propylene glycol 8.38
    isopropyl acetate 1.92
    DMAc 52.34
    2-ethoxyethanol 24.9
    isopentanol 2.89
    n-heptane 0.03
    ethyl formate 4.51
    1,2-dichloroethane 4.55
    n-hexanol 3.04
    2-methoxyethanol 56.57
    isobutyl acetate 1.49
    tetrachloromethane 1.11
    n-pentyl acetate 2.64
    transcutol 13.09
    n-heptanol 2.11
    ethylbenzene 0.52
    MIBK 2.4
    2-propoxyethanol 29.19
    tert-butanol 4.52
    MTBE 1.39
    2-butoxyethanol 12.31
    propionic acid 6.77
    o-xylene 0.49
    formic acid 17.05
    diethyl ether 2.93
    m-xylene 0.49
    p-xylene 0.72
    chlorobenzene 1.46
    dimethyl carbonate 5.76
    n-octane 0.02
    formamide 22.44
    cyclopentanone 31.67
    2-pentanone 4.95
    anisole 2.5
    cyclopentyl methyl ether 4.85
    gamma-butyrolactone 29.45
    1-methoxy-2-propanol 28.27
    pyridine 15.83
    3-pentanone 3.41
    furfural 18.99
    n-dodecane 0.01
    diethylene glycol 25.63
    diisopropyl ether 0.3
    tert-amyl alcohol 2.24
    acetylacetone 6.81
    n-hexadecane 0.02
    acetophenone 3.32
    methyl propionate 5.44
    isopentyl acetate 1.9
    trichloroethylene 10.7
    n-nonanol 1.18
    cyclohexanol 2.03
    benzyl alcohol 4.98
    2-ethylhexanol 0.77
    isooctanol 1.25
    dipropyl ether 1.15
    1,2-dichlorobenzene 1.28
    ethyl lactate 2.98
    propylene carbonate 6.53
    n-methylformamide 38.41
    2-pentanol 1.5
    n-pentane 0.05
    1-propoxy-2-propanol 10.46
    1-methoxy-2-propyl acetate 5.32
    2-(2-methoxypropoxy) propanol 5.4
    mesitylene 0.24
    ε-caprolactone 9.67
    p-cymene 0.23
    epichlorohydrin 32.45
    1,1,1-trichloroethane 2.27
    2-aminoethanol 16.83
    morpholine-4-carbaldehyde 57.13
    sulfolane 38.78
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 10.55
    n-hexyl acetate 2.7
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 8.22
    sec-butyl acetate 1.15
    tert-butyl acetate 1.84
    decalin 0.04
    glycerin 16.04
    diglyme 16.34
    acrylic acid 8.56
    isopropyl myristate 0.53
    n-butyric acid 6.51
    acetyl acetate 2.33
    di(2-ethylhexyl) phthalate 1.72
    ethyl propionate 2.08
    nitromethane 31.37
    1,2-diethoxyethane 3.15
    benzonitrile 3.09
    trioctyl phosphate 0.99
    1-bromopropane 1.58
    gamma-valerolactone 61.09
    n-decanol 0.59
    triethyl phosphate 1.04
    4-methyl-2-pentanol 0.79
    propionitrile 4.12
    vinylene carbonate 7.86
    1,1,2-trichlorotrifluoroethane 24.65
    DMS 3.16
    cumene 0.32
    2-octanol 0.82
    2-hexanone 3.92
    octyl acetate 1.02
    limonene 0.28
    1,2-dimethoxyethane 27.98
    ethyl orthosilicate 0.95
    tributyl phosphate 0.86
    diacetone alcohol 5.36
    N,N-dimethylaniline 1.77
    acrylonitrile 7.12
    aniline 2.97
    1,3-propanediol 23.81
    bromobenzene 1.1
    dibromomethane 4.1
    1,1,2,2-tetrachloroethane 8.61
    2-methyl-cyclohexyl acetate 1.7
    tetrabutyl urea 1.71
    diisobutyl methanol 0.35
    2-phenylethanol 4.44
    styrene 0.61
    dioctyl adipate 1.42
    dimethyl sulfate 10.88
    ethyl butyrate 1.44
    methyl lactate 7.73
    butyl lactate 3.66
    diethyl carbonate 1.03
    propanediol butyl ether 8.87
    triethyl orthoformate 1.48
    p-tert-butyltoluene 0.21
    methyl 4-tert-butylbenzoate 3.72
    morpholine 40.93
    tert-butylamine 0.94
    n-dodecanol 0.29
    dimethoxymethane 41.46
    ethylene carbonate 5.87
    cyrene 11.11
    2-ethoxyethyl acetate 5.88
    2-ethylhexyl acetate 1.32
    1,2,4-trichlorobenzene 2.11
    4-methylpyridine 8.21
    dibutyl ether 0.57
    2,6-dimethyl-4-heptanol 0.35
    DEF 7.67
    dimethyl isosorbide 9.59
    tetrachloroethylene 5.72
    eugenol 5.13
    triacetin 3.54
    span 80 4.7
    1,4-butanediol 8.43
    1,1-dichloroethane 3.29
    2-methyl-1-pentanol 2.12
    methyl formate 19.98
    2-methyl-1-butanol 2.82
    n-decane 0.03
    butyronitrile 3.19
    3,7-dimethyl-1-octanol 0.63
    1-chlorooctane 0.26
    1-chlorotetradecane 0.06
    n-nonane 0.03
    undecane 0.02
    tert-butylcyclohexane 0.03
    cyclooctane 0.02
    cyclopentanol 6.41
    tetrahydropyran 9.74
    tert-amyl methyl ether 1.01
    2,5,8-trioxanonane 9.02
    1-hexene 0.37
    2-isopropoxyethanol 9.06
    2,2,2-trifluoroethanol 7.17
    methyl butyrate 3.01

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction