gamma-Curcumene

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  • Identifiers

    CAS number
    28976-68-3

    Molecular formula
    C15H24

    SMILES
    CC1=CC=C(CC1)[C@H](C)CCC=C(C)C

    Retention indicies (RI)

    • DB5: 1476.0
    • Carbowax: 1683.0

  • Odor profile

    Woody 69.76%
    Herbal 55.71%
    Sweet 54.59%
    Citrus 54.24%
    Spicy 51.95%
    Floral 51.18%
    Balsamic 50.39%
    Tropical 46.69%
    Fresh 45.7%
    Terpenic 44.82%

    Scent© AI

  • Properties

    XLogP3-AA
    4.7

    Molecular weight
    204.35 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    264°C

    Flash point est.
    104.72 ˚C

  • Synonyms

    • gamma-Curcumene
    • 28976-68-3
    • T89VH793AF
    • UNII-T89VH793AF
    • CHEBI:63696
    • 1,3-Cyclohexadiene, 1-(1,5-dimethyl-4-hexenyl)-4-methyl-, (R)-
    • 1-((1R)-1,5-Dimethyl-4-hexen-1-yl)-4-methyl-1,3-cyclohexadiene
    • 1,3-Cyclohexadiene, 1-((1R)-1,5-dimethyl-4-hexen-1-yl)-4-methyl-
    • 2-Heptene, 2-methyl-6-(4-methyl-1,3-cyclohexadien-1-yl)-, (R)-(-)-
    • 1-methyl-4-[(2R)-6-methylhept-5-en-2-yl]cyclohexa-1,3-diene
    • 1-methyl-4-((2R)-6-methylhept-5-en-2-yl)cyclohexa-1,3-diene
    • I(3)-Curcumene
    • NGIVKZGKEPRIGG-CQSZACIVSA-N
    • DTXSID901318194
    • C20179
    • Q27132733
    • (R)-1-Methyl-4-(6-methylhept-5-en-2-yl)cyclohexa-1,3-diene

  • Applications

    Gamma-curcumene (CAS 28976-68-3) is a sesquiterpene hydrocarbon found in turmeric and other Zingiberaceae essential oils, used mainly as a natural flavor and fragrance ingredient for its warm, spicy–woody note in perfumes, cosmetics, and personal care, and as a food flavoring where permitted; it is also employed in R&D as a GC–MS reference/chemotaxonomic marker for essential-oil quality control and botanical authentication, and is being investigated for bioactivities (antimicrobial, antioxidant, anti-inflammatory) and for insect-repellent/insecticidal potential of γ‑curcumene‑rich oils to develop natural preservatives and biopesticide formulations, while direct therapeutic use remains largely preclinical and must comply with fragrance/food-safety regulations, and with purity, dosage, and oxidation-stability controls.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 170.97
    methanol 60.71
    isopropanol 166.39
    water 0.01
    ethyl acetate 725.96
    n-propanol 177.9
    acetone 261.43
    n-butanol 281.81
    acetonitrile 117.74
    DMF 101.97
    toluene 950.99
    isobutanol 136.69
    1,4-dioxane 1064.48
    methyl acetate 290.44
    THF 1450.27
    2-butanone 434.71
    n-pentanol 197.41
    sec-butanol 222.38
    n-hexane 641.51
    ethylene glycol 4.48
    NMP 152.43
    cyclohexane 766.6
    DMSO 105.61
    n-butyl acetate 1360.16
    n-octanol 176.76
    chloroform 861.04
    n-propyl acetate 395.15
    acetic acid 49.47
    dichloromethane 693.98
    cyclohexanone 610.68
    propylene glycol 18.52
    isopropyl acetate 599.61
    DMAc 205.08
    2-ethoxyethanol 159.07
    isopentanol 300.93
    n-heptane 686.04
    ethyl formate 111.82
    1,2-dichloroethane 530.77
    n-hexanol 573.87
    2-methoxyethanol 175.68
    isobutyl acetate 334.76
    tetrachloromethane 189.89
    n-pentyl acetate 388.89
    transcutol 1581.3
    n-heptanol 190.91
    ethylbenzene 467.29
    MIBK 431.44
    2-propoxyethanol 471.06
    tert-butanol 299.02
    MTBE 1198.74
    2-butoxyethanol 219.5
    propionic acid 61.98
    o-xylene 434.55
    formic acid 5.2
    diethyl ether 1569.67
    m-xylene 556.81
    p-xylene 444.42
    chlorobenzene 376.51
    dimethyl carbonate 62.07
    n-octane 156.49
    formamide 9.83
    cyclopentanone 423.04
    2-pentanone 539.73
    anisole 547.2
    cyclopentyl methyl ether 909.93
    gamma-butyrolactone 245.94
    1-methoxy-2-propanol 208.35
    pyridine 661.92
    3-pentanone 466.0
    furfural 195.44
    n-dodecane 73.18
    diethylene glycol 103.3
    diisopropyl ether 716.91
    tert-amyl alcohol 321.53
    acetylacetone 390.71
    n-hexadecane 88.37
    acetophenone 292.92
    methyl propionate 293.1
    isopentyl acetate 1181.47
    trichloroethylene 713.22
    n-nonanol 192.35
    cyclohexanol 318.48
    benzyl alcohol 150.08
    2-ethylhexanol 630.03
    isooctanol 182.12
    dipropyl ether 2064.27
    1,2-dichlorobenzene 319.05
    ethyl lactate 73.61
    propylene carbonate 187.09
    n-methylformamide 31.01
    2-pentanol 293.96
    n-pentane 413.45
    1-propoxy-2-propanol 583.42
    1-methoxy-2-propyl acetate 837.46
    2-(2-methoxypropoxy) propanol 365.97
    mesitylene 377.84
    ε-caprolactone 489.07
    p-cymene 395.92
    epichlorohydrin 515.38
    1,1,1-trichloroethane 643.72
    2-aminoethanol 19.73
    morpholine-4-carbaldehyde 278.74
    sulfolane 219.22
    2,2,4-trimethylpentane 176.8
    2-methyltetrahydrofuran 1311.82
    n-hexyl acetate 545.3
    isooctane 158.5
    2-(2-butoxyethoxy)ethanol 446.83
    sec-butyl acetate 439.54
    tert-butyl acetate 747.67
    decalin 295.54
    glycerin 20.36
    diglyme 914.65
    acrylic acid 29.7
    isopropyl myristate 314.7
    n-butyric acid 220.84
    acetyl acetate 298.62
    di(2-ethylhexyl) phthalate 181.7
    ethyl propionate 377.03
    nitromethane 80.93
    1,2-diethoxyethane 1925.81
    benzonitrile 211.08
    trioctyl phosphate 111.83
    1-bromopropane 822.5
    gamma-valerolactone 418.16
    n-decanol 148.88
    triethyl phosphate 246.13
    4-methyl-2-pentanol 214.75
    propionitrile 189.87
    vinylene carbonate 134.12
    1,1,2-trichlorotrifluoroethane 155.41
    DMS 246.45
    cumene 310.45
    2-octanol 143.4
    2-hexanone 463.82
    octyl acetate 306.75
    limonene 701.14
    1,2-dimethoxyethane 627.81
    ethyl orthosilicate 312.07
    tributyl phosphate 161.69
    diacetone alcohol 331.81
    N,N-dimethylaniline 354.34
    acrylonitrile 106.23
    aniline 311.81
    1,3-propanediol 63.01
    bromobenzene 541.24
    dibromomethane 622.87
    1,1,2,2-tetrachloroethane 667.37
    2-methyl-cyclohexyl acetate 573.76
    tetrabutyl urea 203.34
    diisobutyl methanol 364.82
    2-phenylethanol 328.87
    styrene 476.54
    dioctyl adipate 352.97
    dimethyl sulfate 63.08
    ethyl butyrate 955.65
    methyl lactate 52.76
    butyl lactate 147.27
    diethyl carbonate 422.29
    propanediol butyl ether 124.78
    triethyl orthoformate 648.56
    p-tert-butyltoluene 411.5
    methyl 4-tert-butylbenzoate 321.91
    morpholine 980.57
    tert-butylamine 340.64
    n-dodecanol 126.27
    dimethoxymethane 295.22
    ethylene carbonate 145.4
    cyrene 146.9
    2-ethoxyethyl acetate 513.94
    2-ethylhexyl acetate 1111.82
    1,2,4-trichlorobenzene 355.84
    4-methylpyridine 647.81
    dibutyl ether 1039.19
    2,6-dimethyl-4-heptanol 364.82
    DEF 413.65
    dimethyl isosorbide 649.91
    tetrachloroethylene 367.83
    eugenol 199.9
    triacetin 329.74
    span 80 281.76
    1,4-butanediol 18.65
    1,1-dichloroethane 519.24
    2-methyl-1-pentanol 267.87
    methyl formate 23.86
    2-methyl-1-butanol 261.82
    n-decane 145.75
    butyronitrile 327.08
    3,7-dimethyl-1-octanol 283.2
    1-chlorooctane 354.03
    1-chlorotetradecane 148.7
    n-nonane 161.78
    undecane 96.62
    tert-butylcyclohexane 267.95
    cyclooctane 377.67
    cyclopentanol 165.45
    tetrahydropyran 1787.16
    tert-amyl methyl ether 899.68
    2,5,8-trioxanonane 621.47
    1-hexene 1017.13
    2-isopropoxyethanol 170.92
    2,2,2-trifluoroethanol 10.23
    methyl butyrate 386.15

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Helichrysum italicum (Yugoslavia) 8023-95-8 Helichrysum italicum (Roth) G. Don (H. angustifolium D.C.), fam.Asteraceae 10.4%
Senecio Senecio glaucus ssp. coronopifolius (Maire Alexander), fam. Asteraceae 1.5%
Populus deltoides Populus deltoides Bartr. (P. deltoides Marsh.), fam. Salicaceae 6.4%
Sandalwood, indian (India) 2 8006-87-9 Santalum album L., fam. Santalaceae 0.04%
Santolina chamaecyparisus (France) 3 84961-58-0 Santolina chamaecyparisus L., fam. Asteraceae (Compositae) 1.81%
Cedrus atlantica (Morocco) Cedrus atlantica Man., fam. Cupressaceae 0.4%
Peucedanum zenkeri (Cameroon) 1a Peucedanum zenkeri Engl., fam. Apiaceae (Umbelliferae) 0.7%
Peucedanum zenkeri (Cameroon) 1b Peucedanum zenkeri Engl., fam. Apiaceae (Umbelliferae) 0.5%
Phoebe 1 Phoebe porosa Mez. (syn. Oreodaphne porosa Nees et Mart.), fam. Lauraceae 0.8%
Helichrysum italicum 1a 8023-95-8 Helichrysum italicum (Roth) G. Don ssp. italicum, fam. Asteraceae 15.98%
Helichrysum italicum 1b 8023-95-8 Helichrysum italicum ssp. microphyllum (Willd.) Nyman, fam. Asteraceae 0.02%
Helichrysum italicum (Croatia) 1b 8023-95-8 Helichrysum italicum (Roth) G. Don, fam. Asteraceae (Compositae) 9.12%
Helichrysum italicum (Croatia) 1a 8023-95-8 Helichrysum italicum (Roth) G. Don, fam. Asteraceae (Compositae) 10.0%
Lime (Mexican, West Indian, Key) (Peru) 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 0.11%
Lime (Mexican, West Indian, Key) (Ivory Coast) 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 0.09%
Cubeb (India) 8007-87-2 Piper cubeba L., fam. Piperaceae 0.01%
Turmeric (China) 1a rhizome 8024-37-1 Curcuma longa L. (C. domestica Val.), fam. Zingiberaceae 2.17%
Turmeric (China) 3 8024-37-1 Curcuma longa L. (C. domestica Val.), fam. Zingiberaceae 0.04%
Tejpat leaf (cinnamaldehyde-type) 2 Cinnamomum tamala (Ham.) Nees et Eberm., fam. Lauraceae 0.67%
Helichrysum litoreum (Italy) 1a flower Helichrysum litoreum Guss., fam. Asteraceae (Compositae) 5.6%
Helichrysum litoreum (Italy) 1b stem Helichrysum litoreum Guss., fam. Asteraceae (Compositae) 0.05%
Helichrysum italicum (France-Corsica) 8025-95-8 Helichyrsum italicum (Roth) G. Don ssp.italicum, fam. Asteraceae (Compos.) 11.7%
Santolina insularis (Italy) 1a CO2-extract Santolina insularis L., fam. Asteraceae (Compositae) 4.6%
Santolina insularis (Italy) 1b hydrodistilled Santolina insularis L., fam. Asteraceae (Compositae) 1.0%
Inula verbascifolia ssp. methanea Inula verbascifolia ssp methanea (Hausskn.) Turin, fam. Asteraceae 1.3%
Salvia argentea (Greece) Salvia argentea L., fam. Lamiaceae (Labiatae) 0.05%
Eugenia klappenbachiana (Brazil) Eugenia klappenbachiana Mattos et D. Legrand, fam. Myrtaceae 2.9%
Coespeletia moritziana leaf (Venezuela) Coespeletia moritziana (Sch. Bip. ex Wedd.) Cuatr., fam. Asteraceae 0.05%
Coespeletia spicata leaf (Venezuela) Coespeletia spicata (Sch. Bip. ex Wedd.) Cuatr., fam. Asteraceae 0.35%