Galanolactone

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  • Identifiers

    CAS number
    115753-79-2

    Molecular formula
    C20H30O3

    SMILES
    C[C@]12CCCC([C@@H]1CCC3([C@@H]2C/C=C/4\CCOC4=O)CO3)(C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 75.09%
    Amber 47.67%
    Cedar 38.11%
    Dry 37.14%
    Musk 37.13%
    Powdery 33.38%
    Sandalwood 29.98%
    Tobacco 29.36%
    Spicy 29.04%
    Balsamic 28.82%

     

    Flavor
    Bitter 32.98%
    Woody 28.08%
    Herbal 25.77%
    Fresh 24.37%
    Spicy 23.35%
    Ripe apricot 22.34%
    Cedarleaf 22.14%
    Spice 21.87%
    Red fruit 21.61%
    Lovage 21.46%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.6

    pKa est.
    7.35 (neutral)

    Molecular weight
    318.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    429°C

    Flash point

    • 154.33 ˚C est.

  • Synonyms

    • Galanolactone
    • 115753-79-2
    • DTXSID701028278
    • 2(3H)-Furanone, dihydro-3-(2-(octahydro-5,5,8a-trimethylspiro(naphthalene-2(1H),2'-oxiran)-1-yl)ethylidene)-, (1R-(1alpha(E),2alpha,4abeta,8aalpha))-
    • RefChem:922011
    • DTXCID201513858
    • (3Z)-3-(2-(5,5,8a-trimethyl-octahydro-1H-spiro(naphthalene-2,2'-oxirane)-1-yl)ethylidene)oxolan-2-one
    • (3E)-3-[2-[(1R,4aS,8aS)-5,5,8a-trimethylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]ethylidene]oxolan-2-one
    • 4FX4852TYQ
    • UNII-4FX4852TYQ
    • F92893
    • (1R-(1alpha(E),2alpha,4abeta,8aalpha))-Dihydro-3-(2-(octahydro-5,5,8a-trimethylspiro(naphthalene-2(1H),2'-oxiran)-1-yl)ethylidene)-2(3H)-furanone
    • Dihydro-3-(2-(octahydro-5,5,8a-trimethylspiro(naphthalene-2(1H),2'-oxiran)-1-yl)ethylidene)-2(3H)-furanone (1R-(1alpha(E),2alpha,4abeta,8aalpha))-
    • 115753-79-2

  • Applications

    Galanolactone (CAS 115753-79-2) is primarily used as a fragrance ingredient in perfumery and cosmetics, delivering distinctive aroma notes and can function as an odorant and fixative in personal-care formulations. It is commonly evaluated for flavor/aroma applications in food and beverage contexts. The lactone can serve as a precursor or intermediate in the synthesis of more complex aroma compounds. It may also be incorporated into household and cleaning products as a fragrance component. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 50.51
    methanol 27.84
    isopropanol 42.83
    water 0.08
    ethyl acetate 157.28
    n-propanol 59.72
    acetone 123.68
    n-butanol 58.78
    acetonitrile 93.84
    DMF 151.37
    toluene 213.45
    isobutanol 42.59
    1,4-dioxane 185.85
    methyl acetate 105.4
    THF 343.02
    2-butanone 129.65
    n-pentanol 34.79
    sec-butanol 35.77
    n-hexane 2.93
    ethylene glycol 8.67
    NMP 166.1
    cyclohexane 11.0
    DMSO 70.32
    n-butyl acetate 82.92
    n-octanol 13.12
    chloroform 552.08
    n-propyl acetate 75.95
    acetic acid 86.28
    dichloromethane 387.68
    cyclohexanone 201.96
    propylene glycol 14.71
    isopropyl acetate 131.9
    DMAc 183.46
    2-ethoxyethanol 80.82
    isopentanol 53.53
    n-heptane 2.55
    ethyl formate 57.76
    1,2-dichloroethane 205.5
    n-hexanol 44.3
    2-methoxyethanol 123.2
    isobutyl acetate 62.07
    tetrachloromethane 49.64
    n-pentyl acetate 55.25
    transcutol 296.86
    n-heptanol 21.3
    ethylbenzene 53.75
    MIBK 105.53
    2-propoxyethanol 130.73
    tert-butanol 43.07
    MTBE 66.73
    2-butoxyethanol 73.14
    propionic acid 54.61
    o-xylene 82.64
    formic acid 29.39
    diethyl ether 103.77
    m-xylene 111.14
    p-xylene 59.54
    chlorobenzene 193.24
    dimethyl carbonate 87.65
    n-octane 0.77
    formamide 57.66
    cyclopentanone 232.98
    2-pentanone 136.36
    anisole 133.82
    cyclopentyl methyl ether 164.48
    gamma-butyrolactone 220.83
    1-methoxy-2-propanol 120.6
    pyridine 282.03
    3-pentanone 116.91
    furfural 232.99
    n-dodecane 0.71
    diethylene glycol 86.85
    diisopropyl ether 36.72
    tert-amyl alcohol 33.93
    acetylacetone 196.04
    n-hexadecane 0.9
    acetophenone 115.86
    methyl propionate 125.94
    isopentyl acetate 87.7
    trichloroethylene 498.46
    n-nonanol 15.95
    cyclohexanol 61.56
    benzyl alcohol 85.86
    2-ethylhexanol 27.84
    isooctanol 20.01
    dipropyl ether 42.65
    1,2-dichlorobenzene 166.27
    ethyl lactate 47.52
    propylene carbonate 130.81
    n-methylformamide 75.73
    2-pentanol 39.4
    n-pentane 4.68
    1-propoxy-2-propanol 86.74
    1-methoxy-2-propyl acetate 164.69
    2-(2-methoxypropoxy) propanol 79.94
    mesitylene 52.54
    ε-caprolactone 174.94
    p-cymene 28.78
    epichlorohydrin 349.29
    1,1,1-trichloroethane 193.78
    2-aminoethanol 26.49
    morpholine-4-carbaldehyde 212.17
    sulfolane 185.84
    2,2,4-trimethylpentane 3.28
    2-methyltetrahydrofuran 179.96
    n-hexyl acetate 60.31
    isooctane 3.16
    2-(2-butoxyethoxy)ethanol 101.18
    sec-butyl acetate 71.24
    tert-butyl acetate 123.9
    decalin 5.56
    glycerin 29.72
    diglyme 213.37
    acrylic acid 57.83
    isopropyl myristate 24.54
    n-butyric acid 104.57
    acetyl acetate 138.01
    di(2-ethylhexyl) phthalate 35.58
    ethyl propionate 84.87
    nitromethane 164.46
    1,2-diethoxyethane 90.67
    benzonitrile 125.77
    trioctyl phosphate 19.58
    1-bromopropane 102.85
    gamma-valerolactone 324.21
    n-decanol 10.99
    triethyl phosphate 39.99
    4-methyl-2-pentanol 32.46
    propionitrile 89.55
    vinylene carbonate 144.02
    1,1,2-trichlorotrifluoroethane 201.45
    DMS 93.73
    cumene 31.4
    2-octanol 10.68
    2-hexanone 67.17
    octyl acetate 30.26
    limonene 32.17
    1,2-dimethoxyethane 129.86
    ethyl orthosilicate 38.67
    tributyl phosphate 25.3
    diacetone alcohol 103.12
    N,N-dimethylaniline 71.39
    acrylonitrile 117.2
    aniline 157.04
    1,3-propanediol 52.15
    bromobenzene 218.93
    dibromomethane 226.84
    1,1,2,2-tetrachloroethane 336.64
    2-methyl-cyclohexyl acetate 62.92
    tetrabutyl urea 32.03
    diisobutyl methanol 19.45
    2-phenylethanol 96.06
    styrene 71.03
    dioctyl adipate 42.76
    dimethyl sulfate 111.5
    ethyl butyrate 72.51
    methyl lactate 67.57
    butyl lactate 48.38
    diethyl carbonate 54.24
    propanediol butyl ether 47.0
    triethyl orthoformate 57.84
    p-tert-butyltoluene 27.77
    methyl 4-tert-butylbenzoate 89.53
    morpholine 217.89
    tert-butylamine 29.26
    n-dodecanol 7.66
    dimethoxymethane 180.03
    ethylene carbonate 118.2
    cyrene 84.58
    2-ethoxyethyl acetate 116.15
    2-ethylhexyl acetate 69.12
    1,2,4-trichlorobenzene 205.25
    4-methylpyridine 261.91
    dibutyl ether 19.71
    2,6-dimethyl-4-heptanol 19.45
    DEF 122.63
    dimethyl isosorbide 148.39
    tetrachloroethylene 191.11
    eugenol 79.25
    triacetin 99.93
    span 80 56.21
    1,4-butanediol 18.29
    1,1-dichloroethane 197.22
    2-methyl-1-pentanol 34.48
    methyl formate 55.87
    2-methyl-1-butanol 45.4
    n-decane 1.38
    butyronitrile 85.46
    3,7-dimethyl-1-octanol 21.57
    1-chlorooctane 10.4
    1-chlorotetradecane 3.92
    n-nonane 1.06
    undecane 0.96
    tert-butylcyclohexane 4.42
    cyclooctane 4.1
    cyclopentanol 62.78
    tetrahydropyran 193.42
    tert-amyl methyl ether 53.64
    2,5,8-trioxanonane 133.63
    1-hexene 14.86
    2-isopropoxyethanol 62.77
    2,2,2-trifluoroethanol 50.04
    methyl butyrate 87.9

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction