Furanodienon

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  • Identifiers

    CAS number
    24268-41-5

    Molecular formula
    C15H18O2

    SMILES
    C/C/1=C/C(=O)C2=C(C/C(=C\CC1)/C)OC=C2C

  • Odor profile

    Mint 52.4%
    Sweet 46.9%
    Herbal 46.3%
    Fruity 45.19%
    Tobacco 44.26%
    Spicy 43.61%
    Coumarinic 37.05%
    Woody 35.22%
    Phenolic 35.12%
    Hay 35.07%

    Scent© AI

  • Properties

    XLogP3-AA
    2.9

    Molecular weight
    230.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    420°C

    Flash point est.
    155.02 ˚C

  • Synonyms

    • Furanodienon
    • Furanodienone
    • 24268-41-5
    • 88010-63-3
    • (5Z,9Z)-3,6,10-trimethyl-8,11-dihydro-7H-cyclodeca[b]furan-4-one
    • (5Z,9Z)-3,6,10-Trimethyl-7,8-dihydrocyclodeca[b]furan-4(11H)-one
    • DH78SKJ88K
    • UNII-DH78SKJ88K
    • CHEMBL509404
    • (5E,9E)-3,6,10-Trimethyl-7,8-dihydrocyclodeca[b]furan-4(11H)-one
    • XVOHELPNOXGRBQ-LXQMTTSMSA-N
    • HY-N12454
    • DA-53441
    • DA-63637
    • CS-0907017

  • Applications

    Furanodienone (CAS 24268-41-5) is a natural furanosesquiterpenoid and a characteristic constituent of myrrh (Commiphora spp.), used mainly in research: as a reference standard in HPLC/GC-MS for qualitative and quantitative profiling and standardization of myrrh materials and extracts; as a scaffold for semisynthesis and activity optimization of sesquiterpene derivatives; as a bioactive probe in mechanism-focused assays (anti-inflammatory, antimicrobial, anticancer) given reports of NF-kB inhibition, mitochondrial-pathway apoptosis, and modulation of oxidative stress; in ADME/PK, metabolism, and biomarker studies; to build spectral libraries and authentication criteria (NMR, MS, UV); and occasionally in agro/biochemical evaluations for lab-scale antimicrobial or insect-affecting potential, although direct commercial applications remain limited.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 117.53
    methanol 134.23
    isopropanol 92.42
    water 0.23
    ethyl acetate 98.01
    n-propanol 130.96
    acetone 139.36
    n-butanol 136.85
    acetonitrile 84.96
    DMF 378.6
    toluene 198.91
    isobutanol 118.04
    1,4-dioxane 343.85
    methyl acetate 124.38
    THF 458.08
    2-butanone 165.51
    n-pentanol 126.01
    sec-butanol 111.21
    n-hexane 9.89
    ethylene glycol 27.16
    NMP 369.13
    cyclohexane 37.9
    DMSO 149.72
    n-butyl acetate 123.85
    n-octanol 87.11
    chloroform 745.42
    n-propyl acetate 96.79
    acetic acid 108.06
    dichloromethane 519.22
    cyclohexanone 331.62
    propylene glycol 58.91
    isopropyl acetate 70.3
    DMAc 288.75
    2-ethoxyethanol 122.75
    isopentanol 125.04
    n-heptane 12.48
    ethyl formate 121.49
    1,2-dichloroethane 231.51
    n-hexanol 155.52
    2-methoxyethanol 187.75
    isobutyl acetate 87.73
    tetrachloromethane 71.24
    n-pentyl acetate 105.31
    transcutol 342.89
    n-heptanol 90.04
    ethylbenzene 98.3
    MIBK 90.76
    2-propoxyethanol 198.19
    tert-butanol 102.26
    MTBE 71.67
    2-butoxyethanol 139.45
    propionic acid 101.67
    o-xylene 101.17
    formic acid 34.37
    diethyl ether 69.14
    m-xylene 115.48
    p-xylene 133.97
    chlorobenzene 231.36
    dimethyl carbonate 62.8
    n-octane 7.75
    formamide 60.68
    cyclopentanone 325.83
    2-pentanone 122.94
    anisole 150.06
    cyclopentyl methyl ether 175.12
    gamma-butyrolactone 299.38
    1-methoxy-2-propanol 142.96
    pyridine 374.58
    3-pentanone 102.9
    furfural 323.05
    n-dodecane 9.93
    diethylene glycol 136.14
    diisopropyl ether 29.39
    tert-amyl alcohol 99.06
    acetylacetone 115.79
    n-hexadecane 11.63
    acetophenone 156.16
    methyl propionate 104.04
    isopentyl acetate 123.68
    trichloroethylene 532.88
    n-nonanol 81.77
    cyclohexanol 180.1
    benzyl alcohol 182.0
    2-ethylhexanol 100.57
    isooctanol 74.59
    dipropyl ether 65.83
    1,2-dichlorobenzene 180.87
    ethyl lactate 70.07
    propylene carbonate 210.04
    n-methylformamide 129.97
    2-pentanol 81.31
    n-pentane 10.08
    1-propoxy-2-propanol 137.08
    1-methoxy-2-propyl acetate 120.36
    2-(2-methoxypropoxy) propanol 144.1
    mesitylene 61.23
    ε-caprolactone 259.13
    p-cymene 63.29
    epichlorohydrin 346.35
    1,1,1-trichloroethane 216.91
    2-aminoethanol 71.16
    morpholine-4-carbaldehyde 323.83
    sulfolane 282.76
    2,2,4-trimethylpentane 10.05
    2-methyltetrahydrofuran 266.35
    n-hexyl acetate 145.11
    isooctane 7.38
    2-(2-butoxyethoxy)ethanol 179.38
    sec-butyl acetate 74.69
    tert-butyl acetate 78.13
    decalin 23.7
    glycerin 76.63
    diglyme 253.77
    acrylic acid 96.25
    isopropyl myristate 70.24
    n-butyric acid 152.52
    acetyl acetate 75.53
    di(2-ethylhexyl) phthalate 95.05
    ethyl propionate 78.87
    nitromethane 146.13
    1,2-diethoxyethane 122.25
    benzonitrile 213.09
    trioctyl phosphate 62.9
    1-bromopropane 146.28
    gamma-valerolactone 400.06
    n-decanol 64.84
    triethyl phosphate 62.93
    4-methyl-2-pentanol 56.36
    propionitrile 109.22
    vinylene carbonate 210.36
    1,1,2-trichlorotrifluoroethane 238.05
    DMS 116.51
    cumene 67.5
    2-octanol 65.46
    2-hexanone 120.06
    octyl acetate 91.05
    limonene 81.39
    1,2-dimethoxyethane 214.89
    ethyl orthosilicate 62.3
    tributyl phosphate 70.41
    diacetone alcohol 108.45
    N,N-dimethylaniline 114.22
    acrylonitrile 139.7
    aniline 200.62
    1,3-propanediol 106.54
    bromobenzene 250.99
    dibromomethane 339.94
    1,1,2,2-tetrachloroethane 409.65
    2-methyl-cyclohexyl acetate 116.79
    tetrabutyl urea 97.12
    diisobutyl methanol 48.87
    2-phenylethanol 182.15
    styrene 118.2
    dioctyl adipate 105.4
    dimethyl sulfate 81.2
    ethyl butyrate 91.5
    methyl lactate 71.71
    butyl lactate 99.52
    diethyl carbonate 75.17
    propanediol butyl ether 140.4
    triethyl orthoformate 78.77
    p-tert-butyltoluene 58.31
    methyl 4-tert-butylbenzoate 128.19
    morpholine 376.54
    tert-butylamine 68.71
    n-dodecanol 51.88
    dimethoxymethane 173.17
    ethylene carbonate 163.16
    cyrene 177.19
    2-ethoxyethyl acetate 138.71
    2-ethylhexyl acetate 106.83
    1,2,4-trichlorobenzene 232.35
    4-methylpyridine 357.93
    dibutyl ether 72.6
    2,6-dimethyl-4-heptanol 48.87
    DEF 152.01
    dimethyl isosorbide 228.69
    tetrachloroethylene 251.37
    eugenol 143.11
    triacetin 129.37
    span 80 150.57
    1,4-butanediol 67.05
    1,1-dichloroethane 227.74
    2-methyl-1-pentanol 135.15
    methyl formate 113.84
    2-methyl-1-butanol 133.12
    n-decane 14.4
    butyronitrile 138.42
    3,7-dimethyl-1-octanol 80.48
    1-chlorooctane 60.57
    1-chlorotetradecane 30.92
    n-nonane 12.24
    undecane 11.6
    tert-butylcyclohexane 18.68
    cyclooctane 10.95
    cyclopentanol 176.44
    tetrahydropyran 287.77
    tert-amyl methyl ether 68.76
    2,5,8-trioxanonane 203.22
    1-hexene 51.74
    2-isopropoxyethanol 106.01
    2,2,2-trifluoroethanol 42.92
    methyl butyrate 116.98

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Myrrh gum (headspace) 8016-37-3 Commiphora myrrha (Nees) Engler, fam. Burseraceae 0.4%
Curcuma aeruginosa (Malaysia) 1 Curcuma aeruginosa Roxb., fam. Zingiberaceae 2.3%
Curcuma aromatica (India) 2a leaf Curcuma aromatica Salisb., fam. Zingiberaceae 1.5%