Formothion

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  • Identifiers

    CAS number
    2540-82-1

    Molecular formula
    C6H12NO4PS2

    SMILES
    CN(C=O)C(=O)CSP(=S)(OC)OC

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sulfurous 51.21%
    Meaty 39.29%
    Savory 38.93%
    Roasted 38.48%
    Onion 36.2%
    Odorless 33.2%
    Cooked 31.88%
    Cheesy 25.74%
    Fresh 25.19%
    Garlic 24.81%

     

    Flavor
    Cooked 35.48%
    Roasted 28.5%
    Cabbage 26.39%
    Onion 23.5%
    Odorless 22.09%
    Sulfury 21.75%
    Taco 21.59%
    Nutty 21.45%
    Bitter 20.9%
    Sulfurous 20.74%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.5

    pKa est.
    3.98 (weak acid)

    Molecular weight
    257.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Melting point expt.

    • 77 °F (EPA, 1998)
    • 25-26 °C

    Boiling point

    • Decomposes on distillation

    Flash point

    • 127.78 ˚C est.

    Solubility expt.

    • Completely miscible with common organic solvents, e.g. alcohols, ethers, ketones, chloroform, benzene, toluene, xylene; slightly soluble in hexane; very slightly soluble in ligroin and paraffin oil.
    • MISCIBLE WITH ... DIETHYL ETHER
    • In water, 2.6X10+3 mg/L at 24 °C

  • Synonyms

    • FORMOTHION
    • 2540-82-1
    • Anthio
    • Toprose
    • Aflix
    • Antio
    • Anthio 25
    • Spencer S-6900
    • Afliz [Sandoz]
    • Sandoz S-6900
    • Formothion 25 EC
    • Afliz
    • OMS-968
    • Caswell No. 366C
    • Formothion [BSI:ISO]
    • SAN 244 I
    • SAN 6913 I
    • SAN 7107 I
    • VEL 4284
    • CCRIS 5213
    • ENT 27,257
    • HSDB 1587
    • CP 53926
    • J-38
    • EINECS 219-818-6
    • UNII-7O9EWV477R
    • S 6900
    • EPA Pesticide Chemical Code 366400
    • BRN 5942199
    • 7O9EWV477R
    • CHEBI:82126
    • AI3-27257
    • S-(N-Formyl-N-methylcarbamoylmethyl) O,O-dimethyl phosphorodithioate
    • FORMOTHION [MI]
    • Phosphorodithioic acid, S-(2-(formylmethylamino)-2-oxoethyl) O,O-dimethyl ester
    • FORMOTHION [ISO]
    • FORMOTHION [HSDB]
    • N-Formyl-N-methylcarbamoylmethyl O,O-dimethyl phosphorodithioate
    • O,O-Dimethyl dithiophosphorylacetic acid N-methyl-N-formylamide
    • O,O-Dimethyl S-(N-methyl-N-formylcarbamoylmethyl)phosphorodithioate
    • S-(Formyl(methyl)carbamoylmethyl) O,O-dimethyl phosphorodithioate
    • O,O-Dimethyl S-(N-formyl-N-methylcarbamoylmethyl) phosphorodithioate
    • S-(2-(Formylmethylamino)-2-oxoethyl) O,O-dimethyl phosphorodithioate
    • S-(2-(Formylmethylamino)-2-oxoethyl) O,O-dimethylphosphorodithioate
    • S-(N-Formyl-N-methylcarbamoylmethyl) dimethyl phosphorothiolothionate
    • O,O-Dimethyl phosphorodithioate N-formyl-2-mercapto-N-methylacetamide S-ester
    • 2-Dimethoxyphosphinothioylthio-N-formyl-N-methylacetamide
    • Acetamide, N-formyl-2-mercapto-N-methyl-, S-ester with O,O-dimethyl phosphorodithioate
    • Phosphorodithioic acid, O,O-dimethyl ester, N-formyl-2-mercapto-N-methylacetamide S-ester
    • 2-dimethoxyphosphinothioylsulfanyl-N-formyl-N-methylacetamide
    • DTXSID4041991
    • Afliz (Sandoz)
    • O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-aza-butyl)-dithiofosfaat [Dutch]
    • O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-aza-butyl)-dithiophosphat [German]
    • O,O-Dimetil-S-(N-formil-N-metil-carbamoil-metil)-ditiofosfato [Italian]
    • O,O-Dimethyl phosphorodithioate S-ester with N-formyl-2-mercapto-N-methylacetamide
    • O,O-Dimethyl-S-(N-methyl-N-formyl-carbamoylmethyl)-dithiophosphat [German]
    • Phosphorodithioic acid S-(2-(formylmethylamino)-2-oxoethyl) O,O-dimethyl ester
    • Phosphorodithioic acid, S-[2-(formylmethylamino)-2-oxoethyl] O,O-dimethyl ester
    • O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-aza-butyl)-dithiofosfaat
    • O,O-Dimetil-S-(N-formil-N-metil-carbamoil-metil)-ditiofosfato
    • Anthio 25;ENT 27257;CP 53926
    • O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-aza-butyl)-dithiophosphat
    • O,O-Dimethyl-s-(N-methyl-N-formyl-carbamoylmethyl)-dithiophosphat
    • phosphorodithioic acid O,O-dimethyl ester S-ester with N-formyl-2-mercapto-N-methylacetamide
    • Phosphorodithioic acid, O,O-dimethyl ester, S-ester with N-formyl-2-mercapto-N-methyl-acetamide
    • Phosphorodithioic acid, O,O-dimethyl ester, S-ester with N-formyl-2-mercapto-N-methylacetamide
    • O,O-Dimetil-S-(N-formil-N-metilcarbamoilmetil)ditiofosfato
    • O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-azabutyl)dithiofosfaat
    • O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-azabutyl)dithiophosphat
    • O,O-Dimethyl-S-(N-methyl-N-formylcarbamoylmethyl)dithiophosphat
    • Formotion
    • O,O-dimethyl-S-(N-methyl-N-formyl-carbamoylmethyl)-dithiophosphat (German)
    • O,O-DIMETHYL-S-(3-METHYL-2,4-DIOXO-3-AZA-BUTYL)-DITHIOFOSFAAT (DUTCH)
    • O,O-DIMETHYL-S-(3-METHYL-2,4-DIOXO-3-AZA-BUTYL)-DITHIOPHOSPHAT (GERMAN)
    • O,O-DIMETIL-S-(N-FORMIL-N-METIL-CARBAMOIL-METIL)-DITIOFOSFATO (ITALIAN)
    • Formotion (Spanish)
    • FORMITHION
    • Spencer S6900
    • Sandoz S6900
    • Formothion 100 microg/mL in Acetonitrile
    • ANTHIO 33
    • SCHEMBL116325
    • CHEMBL449733
    • OMS968
    • DTXCID2021991
    • ENT 27257
    • S-[2-(Formylmethylamino)-2-oxoethyl] O,O-dimethyl dithiophosphate
    • AKOS015898765
    • NS00004887
    • C18988
    • 2DimethoxyphosphinothioylthioNformylNmethylacetamide
    • O,ODimethylS(3methyl2,4dioxo3azabutyl)dithiofosfaat
    • O,ODimetilS(NformilNmetilcarbamoilmetil)ditiofosfato
    • Q5470249
    • O,ODimethylS(3methyl2,4dioxo3azabutyl)dithiophosphat
    • O,ODimethylS(NmethylNformylcarbamoylmethyl)dithiophosphat
    • NFormylNmethylcarbamoylmethyl O,Odimethyl phosphorodithioate
    • O,ODimethyl dithiophosphorylacetic acid NmethylNformylamide
    • O,ODimethyl S(NformylNmethylcarbamoylmethyl) phosphorodithioate
    • O,ODimethyl S(NmethylNformylcarbamoylmethyl)phosphorodithioate
    • S(2(Formylmethylamino)2oxoethyl) O,Odimethyl phosphorodithioate
    • S(2(Formylmethylamino)2oxoethyl) O,Odimethylphosphorodithioate
    • S(Formyl(methyl)carbamoylmethyl) O,Odimethyl phosphorodithioate
    • S(NFormylNmethylcarbamoylmethyl) dimethyl phosphorothiolothionate
    • S(NFormylNmethylcarbamoylmethyl) O,Odimethyl phosphorodithioate
    • O,O-dimethyl S-(N-methyl-N-formylcarbamoylmethyl) phosphorodithioate
    • N-FORMYL-N-METHYLCARBAMOYLMETHYL O,O-DIMETHYL PHOSPHORODI-THIOATE
    • O,ODimethyl phosphorodithioate Nformyl2mercaptoNmethylacetamide Sester
    • O,ODimethyl phosphorodithioate Sester with Nformyl2mercaptoNmethylacetamide
    • Phosphorodithioic acid, S(2(formylmethylamino)2oxoethyl) O,Odimethyl ester
    • S-(2-[Formyl(methyl)amino]-2-oxoethyl) O,O-dimethyl dithiophosphate #
    • Acetamide, Nformyl2mercaptoNmethyl, Sester with O,Odimethyl phosphorodithioate
    • Phosphorodithioic acid, O,Odimethyl ester, Nformyl2mercaptoNmethylacetamide Sester
    • 219-818-6
    • PHOSPHORODITHIOIC ACID, O,O-DIMETHYL ESTER, N-FORMYL-2-MERCAPTO-N-METHYL-ACETAMIDE S-ESTER

  • Applications

    Formothion (CAS 2540-82-1) is an organophosphate insecticide used primarily in agriculture to control pests on a range of crops, including fruits, vegetables, cereals, and ornamentals. It is typically formulated as emulsifiable concentrates (EC) or granules (GR) for field or greenhouse applications and may be used in post-harvest protection programs to mitigate stored-product insects. As with many organophosphorus pesticides, its use is evaluated in formulation development and residue studies. Application should comply with local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.69
    methanol 24.32
    isopropanol 6.49
    water 6.92
    ethyl acetate 20.69
    n-propanol 7.9
    acetone 27.62
    n-butanol 5.59
    acetonitrile 33.09
    DMF 211.26
    toluene 4.04
    isobutanol 5.17
    1,4-dioxane 50.57
    methyl acetate 35.13
    THF 62.41
    2-butanone 21.73
    n-pentanol 4.22
    sec-butanol 6.21
    n-hexane 0.11
    ethylene glycol 13.98
    NMP 260.21
    cyclohexane 0.85
    DMSO 126.24
    n-butyl acetate 10.44
    n-octanol 3.19
    chloroform 45.95
    n-propyl acetate 12.03
    acetic acid 62.62
    dichloromethane 47.08
    cyclohexanone 43.44
    propylene glycol 7.95
    isopropyl acetate 12.52
    DMAc 206.92
    2-ethoxyethanol 33.97
    isopentanol 5.13
    n-heptane 0.34
    ethyl formate 31.05
    1,2-dichloroethane 24.08
    n-hexanol 4.21
    2-methoxyethanol 70.6
    isobutyl acetate 6.52
    tetrachloromethane 5.38
    n-pentyl acetate 7.73
    transcutol 46.41
    n-heptanol 3.75
    ethylbenzene 2.32
    MIBK 9.6
    2-propoxyethanol 26.33
    tert-butanol 10.47
    MTBE 8.39
    2-butoxyethanol 16.64
    propionic acid 20.37
    o-xylene 5.4
    formic acid 95.05
    diethyl ether 7.7
    m-xylene 2.98
    p-xylene 3.62
    chlorobenzene 11.55
    dimethyl carbonate 29.09
    n-octane 0.21
    formamide 156.71
    cyclopentanone 70.11
    2-pentanone 14.51
    anisole 17.85
    cyclopentyl methyl ether 18.1
    gamma-butyrolactone 101.36
    1-methoxy-2-propanol 32.77
    pyridine 40.28
    3-pentanone 14.04
    furfural 159.41
    n-dodecane 0.21
    diethylene glycol 36.49
    diisopropyl ether 2.06
    tert-amyl alcohol 9.54
    acetylacetone 34.99
    n-hexadecane 0.25
    acetophenone 28.39
    methyl propionate 24.71
    isopentyl acetate 10.41
    trichloroethylene 69.66
    n-nonanol 3.51
    cyclohexanol 8.57
    benzyl alcohol 16.05
    2-ethylhexanol 3.7
    isooctanol 3.28
    dipropyl ether 4.83
    1,2-dichlorobenzene 18.32
    ethyl lactate 15.24
    propylene carbonate 51.74
    n-methylformamide 87.46
    2-pentanol 3.53
    n-pentane 0.21
    1-propoxy-2-propanol 16.68
    1-methoxy-2-propyl acetate 23.86
    2-(2-methoxypropoxy) propanol 24.54
    mesitylene 2.32
    ε-caprolactone 45.04
    p-cymene 3.25
    epichlorohydrin 87.02
    1,1,1-trichloroethane 20.52
    2-aminoethanol 17.2
    morpholine-4-carbaldehyde 193.7
    sulfolane 145.52
    2,2,4-trimethylpentane 0.27
    2-methyltetrahydrofuran 32.42
    n-hexyl acetate 8.9
    isooctane 0.14
    2-(2-butoxyethoxy)ethanol 23.23
    sec-butyl acetate 7.44
    tert-butyl acetate 15.86
    decalin 0.46
    glycerin 27.87
    diglyme 60.11
    acrylic acid 32.34
    isopropyl myristate 4.27
    n-butyric acid 19.04
    acetyl acetate 23.85
    di(2-ethylhexyl) phthalate 8.06
    ethyl propionate 12.83
    nitromethane 207.67
    1,2-diethoxyethane 12.43
    benzonitrile 20.17
    trioctyl phosphate 4.79
    1-bromopropane 4.9
    gamma-valerolactone 143.24
    n-decanol 2.63
    triethyl phosphate 13.81
    4-methyl-2-pentanol 2.59
    propionitrile 15.9
    vinylene carbonate 59.86
    1,1,2-trichlorotrifluoroethane 109.76
    DMS 18.71
    cumene 1.97
    2-octanol 2.49
    2-hexanone 9.48
    octyl acetate 5.72
    limonene 4.49
    1,2-dimethoxyethane 60.96
    ethyl orthosilicate 11.08
    tributyl phosphate 6.31
    diacetone alcohol 24.63
    N,N-dimethylaniline 15.47
    acrylonitrile 33.29
    aniline 13.55
    1,3-propanediol 19.56
    bromobenzene 8.95
    dibromomethane 16.37
    1,1,2,2-tetrachloroethane 52.49
    2-methyl-cyclohexyl acetate 14.19
    tetrabutyl urea 10.78
    diisobutyl methanol 2.85
    2-phenylethanol 13.21
    styrene 3.19
    dioctyl adipate 9.45
    dimethyl sulfate 74.08
    ethyl butyrate 12.19
    methyl lactate 28.33
    butyl lactate 10.24
    diethyl carbonate 12.47
    propanediol butyl ether 12.49
    triethyl orthoformate 12.0
    p-tert-butyltoluene 3.19
    methyl 4-tert-butylbenzoate 22.97
    morpholine 60.7
    tert-butylamine 4.6
    n-dodecanol 2.01
    dimethoxymethane 58.94
    ethylene carbonate 38.95
    cyrene 52.12
    2-ethoxyethyl acetate 17.45
    2-ethylhexyl acetate 8.15
    1,2,4-trichlorobenzene 28.19
    4-methylpyridine 33.99
    dibutyl ether 3.22
    2,6-dimethyl-4-heptanol 2.85
    DEF 43.18
    dimethyl isosorbide 58.69
    tetrachloroethylene 33.78
    eugenol 25.06
    triacetin 22.24
    span 80 15.11
    1,4-butanediol 8.04
    1,1-dichloroethane 14.18
    2-methyl-1-pentanol 4.2
    methyl formate 74.04
    2-methyl-1-butanol 5.26
    n-decane 0.33
    butyronitrile 11.24
    3,7-dimethyl-1-octanol 3.68
    1-chlorooctane 1.57
    1-chlorotetradecane 0.83
    n-nonane 0.26
    undecane 0.25
    tert-butylcyclohexane 0.37
    cyclooctane 0.31
    cyclopentanol 13.67
    tetrahydropyran 18.45
    tert-amyl methyl ether 8.48
    2,5,8-trioxanonane 47.23
    1-hexene 0.56
    2-isopropoxyethanol 17.89
    2,2,2-trifluoroethanol 62.59
    methyl butyrate 18.84

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction