Fonofos

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  • Identifiers

    CAS number
    944-22-9

    Molecular formula
    C10H15OPS2

    SMILES
    CCOP(=S)(CC)SC1=CC=CC=C1

    Safety labels

    Acute Toxic
    Acute Toxic

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Sulfurous 68.68%
    Meaty 55.17%
    Roasted 50.21%
    Fruity 45.33%
    Onion 43.29%
    Savory 38.85%
    Garlic 35.26%
    Cooked 33.98%
    Alliaceous 33.79%
    Tropical 33.67%

     

    Flavor
    Sulfurous 48.46%
    Onion 41.5%
    Sulfury 40.76%
    Meaty 37.93%
    Roasted 35.21%
    Garlic 31.48%
    Cabbage 29.52%
    Alliaceous 27.47%
    Green 26.95%
    Metallic 26.82%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.9

    pKa est.
    3.66 (weak acid)

    Molecular weight
    246.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 30 °C

    Boiling point

    • 266 °F at 0.1 mmHg (EPA, 1998)
    • 130 °C @ 0.1 mm Hg
    • at 0.013kPa: 130 °C
    • 266 °F at 0.1 mmHg

    Flash point

    • 149.32 ˚C est.
    • greater than 201 °F (NIOSH, 2024)
    • >200 °F, 93 °C
    • 94 °C c.c.
    • >201 °F

    Solubility expt.

    • 0.001 % (NIOSH, 2024)
    • Miscible with ... acetone, ethanol, kerosene, methyl isobutyl ketone, xylene.
    • Miscible with organic solvents.
    • In water, 15.7 mg/l @ 20 °C
    • Solubility in water: none
    • 0.001%

  • Synonyms

    • Fonofos
    • Dyfonate
    • 944-22-9
    • DYPHONATE
    • Difonate
    • Difonatul
    • Fonophos
    • Doubledown
    • Fonofos [ISO]
    • Stauffer N 2790
    • (+-)-Fonofos
    • Caswell No. 454B
    • Dyfonate Tillam 1-4E
    • O-Ethyl S-phenyl ethylphosphonodithioate
    • Dyfonat
    • HSDB 1717
    • OMS 410
    • Ethylphosphonodithioic acid O-ethyl S-phenyl ester
    • EINECS 213-408-0
    • Phosphonodithioic acid, ethyl-, O-ethyl S-phenyl ester
    • UNII-P4VT8081QO
    • Dyfonate 10G
    • (+-)-O-Ethyl S-phenyl ethylphosphonodithioate
    • ENT 25,796
    • EPA Pesticide Chemical Code 041701
    • O-Ethyl S-phenyl ethyldithiophosphonate
    • BRN 1958949
    • P4VT8081QO
    • DTXSID2024113
    • CHEBI:38689
    • AI3-25796
    • O-Ethyl S-phenyl ethylphosphonothiolothionate
    • FONOFOS [MI]
    • N-2788
    • O-Aethyl-S-phenyl-aethyl-dithiophosphonat
    • DTXCID104113
    • ethoxy-ethyl-phenylsulfanyl-sulfanylidene-lambda5-phosphane
    • O-Ethyl S-phenyl ethylphosphonrothiolothionate
    • 994-22-9
    • N 2790
    • O-ETHYL S-PHENYL P-ETHYLPHOSPHONODITHIOATE
    • (.+/-.)-O-Ethyl S-phenyl ethylphosphonodithioate
    • Stauffer N2790
    • (RS)-(O-ETHYL S-PHENYL ETHYLPHOSPHONODITHIOATE)
    • Stauffer N-2790
    • O-Ethyl-S-phenyl ethylphosphonodithioate
    • dyfonate/fonofos
    • N-2790
    • Fonofos (ACGIH)
    • O-Aethyl-S-phenyl-aethyl-dithiophosphonat [German]
    • O-Ethyl-S-phenyl ethylphosphorothioate
    • Dyfonate Tillam 14E
    • DYFONATE 20G
    • DYPHONATE [HSDB]
    • SCHEMBL74085
    • (.+-.)-FONOFOS
    • CHEMBL3187845
    • OAethylSphenylaethyldithiophosphonat
    • AAA94422
    • OEthyl Sphenyl ethyldithiophosphonate
    • OEthylSphenyl ethylphosphonodithioate
    • Tox21_200009
    • Fonofos 10 microg/mL in Cyclohexane
    • Fonofos 1000 microg/mL in Methanol
    • AKOS015902803
    • Fonofos 100 microg/mL in Acetonitrile
    • O-Ethyl S-phenylethylphosphonodithioate
    • USEPA/OPP Pesticide Code: 041701
    • NCGC00248489-01
    • NCGC00257563-01
    • O-ethyl S-phenyl ethylphosphonodithiolate
    • CAS-944-22-9
    • OEthyl Sphenyl ethylphosphonothiolothionate
    • DB-057499
    • N2788
    • N2790
    • NS00008243
    • o-ethyl s-phenyl (rs)-ethylphosphonodithioate
    • C18987
    • Ethylphosphonodithioic acid Oethyl Sphenyl ester
    • (+)OEthyl Sphenyl ethylphosphonodithioate (8CI)
    • Phosphonodithioic acid, ethyl, Oethyl Sphenyl ester
    • Q2080990
    • (+)OEthyl Sphenyl ethylphosphonodithioate (8CI)(9CI)
    • ethoxy-ethyl-phenylsulfanyl-sulfanylidene-?5-phosphane
    • (+/-)-O-ETHYL S-PHENYL ETHYLPHOSPHONODITHIOATE
    • 213-408-0

  • Applications

    Fonofos (CAS 944-22-9) is an organophosphate insecticide used in agriculture to protect crops from pests, typically applied as soil granules or foliar/emulsifiable formulations to control pests residing in the soil and on the plant, and used on crops such as corn and vegetables to safeguard yields.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 483.19
    methanol 594.11
    isopropanol 306.31
    water 1.33
    ethyl acetate 514.83
    n-propanol 389.69
    acetone 935.74
    n-butanol 336.36
    acetonitrile 573.97
    DMF 2139.57
    toluene 454.55
    isobutanol 260.45
    1,4-dioxane 1581.13
    methyl acetate 618.26
    THF 1674.79
    2-butanone 655.78
    n-pentanol 268.61
    sec-butanol 257.49
    n-hexane 28.73
    ethylene glycol 199.3
    NMP 1410.82
    cyclohexane 158.57
    DMSO 1650.52
    n-butyl acetate 517.35
    n-octanol 201.05
    chloroform 2201.61
    n-propyl acetate 402.87
    acetic acid 597.27
    dichloromethane 1975.2
    cyclohexanone 1309.94
    propylene glycol 217.38
    isopropyl acetate 316.02
    DMAc 1283.34
    2-ethoxyethanol 548.42
    isopentanol 237.95
    n-heptane 66.16
    ethyl formate 513.99
    1,2-dichloroethane 1187.82
    n-hexanol 310.86
    2-methoxyethanol 856.41
    isobutyl acetate 288.77
    tetrachloromethane 308.16
    n-pentyl acetate 381.97
    transcutol 981.11
    n-heptanol 186.22
    ethylbenzene 183.84
    MIBK 311.1
    2-propoxyethanol 623.12
    tert-butanol 333.04
    MTBE 354.19
    2-butoxyethanol 361.5
    propionic acid 381.46
    o-xylene 244.1
    formic acid 222.88
    diethyl ether 442.88
    m-xylene 243.44
    p-xylene 217.61
    chlorobenzene 692.6
    dimethyl carbonate 342.55
    n-octane 35.87
    formamide 404.91
    cyclopentanone 1393.08
    2-pentanone 485.47
    anisole 493.29
    cyclopentyl methyl ether 652.67
    gamma-butyrolactone 1348.08
    1-methoxy-2-propanol 516.39
    pyridine 1180.55
    3-pentanone 455.96
    furfural 1506.76
    n-dodecane 33.22
    diethylene glycol 550.24
    diisopropyl ether 137.17
    tert-amyl alcohol 266.87
    acetylacetone 733.54
    n-hexadecane 38.07
    acetophenone 492.68
    methyl propionate 468.31
    isopentyl acetate 438.01
    trichloroethylene 2130.03
    n-nonanol 180.48
    cyclohexanol 454.78
    benzyl alcohol 407.49
    2-ethylhexanol 219.46
    isooctanol 157.46
    dipropyl ether 310.99
    1,2-dichlorobenzene 638.11
    ethyl lactate 221.77
    propylene carbonate 740.03
    n-methylformamide 723.21
    2-pentanol 189.81
    n-pentane 45.66
    1-propoxy-2-propanol 416.56
    1-methoxy-2-propyl acetate 515.83
    2-(2-methoxypropoxy) propanol 333.02
    mesitylene 170.88
    ε-caprolactone 945.73
    p-cymene 175.95
    epichlorohydrin 1422.49
    1,1,1-trichloroethane 929.77
    2-aminoethanol 272.9
    morpholine-4-carbaldehyde 1700.18
    sulfolane 1538.44
    2,2,4-trimethylpentane 32.44
    2-methyltetrahydrofuran 925.15
    n-hexyl acetate 426.63
    isooctane 26.29
    2-(2-butoxyethoxy)ethanol 441.67
    sec-butyl acetate 253.8
    tert-butyl acetate 366.96
    decalin 65.66
    glycerin 340.44
    diglyme 914.95
    acrylic acid 398.97
    isopropyl myristate 197.15
    n-butyric acid 494.43
    acetyl acetate 445.42
    di(2-ethylhexyl) phthalate 210.17
    ethyl propionate 311.2
    nitromethane 1348.15
    1,2-diethoxyethane 548.1
    benzonitrile 649.47
    trioctyl phosphate 154.59
    1-bromopropane 524.91
    gamma-valerolactone 2046.19
    n-decanol 142.63
    triethyl phosphate 222.7
    4-methyl-2-pentanol 126.19
    propionitrile 453.67
    vinylene carbonate 872.59
    1,1,2-trichlorotrifluoroethane 1001.83
    DMS 421.3
    cumene 135.45
    2-octanol 151.9
    2-hexanone 401.47
    octyl acetate 240.16
    limonene 263.48
    1,2-dimethoxyethane 1045.42
    ethyl orthosilicate 213.76
    tributyl phosphate 193.0
    diacetone alcohol 383.7
    N,N-dimethylaniline 336.25
    acrylonitrile 568.24
    aniline 484.18
    1,3-propanediol 382.81
    bromobenzene 776.25
    dibromomethane 1170.64
    1,1,2,2-tetrachloroethane 1599.43
    2-methyl-cyclohexyl acetate 366.19
    tetrabutyl urea 278.01
    diisobutyl methanol 145.11
    2-phenylethanol 401.84
    styrene 277.67
    dioctyl adipate 276.94
    dimethyl sulfate 567.27
    ethyl butyrate 364.26
    methyl lactate 296.76
    butyl lactate 300.66
    diethyl carbonate 279.84
    propanediol butyl ether 355.27
    triethyl orthoformate 298.52
    p-tert-butyltoluene 170.51
    methyl 4-tert-butylbenzoate 378.57
    morpholine 1343.72
    tert-butylamine 191.47
    n-dodecanol 118.57
    dimethoxymethane 905.79
    ethylene carbonate 721.05
    cyrene 499.63
    2-ethoxyethyl acetate 533.67
    2-ethylhexyl acetate 401.08
    1,2,4-trichlorobenzene 730.69
    4-methylpyridine 999.72
    dibutyl ether 270.91
    2,6-dimethyl-4-heptanol 145.11
    DEF 704.42
    dimethyl isosorbide 678.69
    tetrachloroethylene 981.99
    eugenol 390.68
    triacetin 432.72
    span 80 335.08
    1,4-butanediol 202.88
    1,1-dichloroethane 879.3
    2-methyl-1-pentanol 222.98
    methyl formate 708.04
    2-methyl-1-butanol 242.31
    n-decane 51.6
    butyronitrile 476.2
    3,7-dimethyl-1-octanol 182.07
    1-chlorooctane 184.21
    1-chlorotetradecane 90.29
    n-nonane 48.75
    undecane 39.91
    tert-butylcyclohexane 51.66
    cyclooctane 55.57
    cyclopentanol 469.61
    tetrahydropyran 1089.66
    tert-amyl methyl ether 276.66
    2,5,8-trioxanonane 636.65
    1-hexene 119.97
    2-isopropoxyethanol 361.55
    2,2,2-trifluoroethanol 268.62
    methyl butyrate 434.87

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction