Fluoroethane

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  • Identifiers

    CAS number
    353-36-6

    Molecular formula
    C2H5F

    SMILES
    CCF

    Safety labels

    Flammable
    Flammable

    Compressed Gas
    Compressed Gas

  • Odor profile

    Fragrance
    Ethereal 54.57%
    Alcoholic 52.16%
    Sweet 50.91%
    Solvent 50.72%
    Fermented 47.74%
    Musty 39.32%
    Fishy 39.29%
    Cheesy 36.43%
    Oily 35.74%
    Gassy 34.42%

     

    Flavor
    Fishy 48.61%
    Onion 32.51%
    Sulfurous 30.52%
    Fruity 30.21%
    Meaty 29.66%
    Ammoniacal 28.98%
    Ammonia 27.32%
    Gassy 25.45%
    Garlic 24.85%
    Egg 24.37%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.9

    pKa est.
    7.79 (neutral)

    Molecular weight
    48.06 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    -37°C

    Flash point

    • -63.96 ˚C est.

  • Synonyms

    • FLUOROETHANE
    • Ethyl fluoride
    • Ethane, fluoro-
    • 353-36-6
    • Monofluoroethane
    • HFC-161
    • C2H5F
    • UNII-XO7SPI984C
    • EINECS 206-531-6
    • XO7SPI984C
    • UN2453
    • BRN 1730748
    • R 161
    • 2C-EF
    • DTXSID2059857
    • HFA-161
    • UN 2453
    • F-161
    • R-161
    • HFC 161
    • CH2CH2F
    • fluoranylethane
    • ethane, fluoro
    • Refrigerant 161
    • 1-Fluoroethane #
    • MFCD00039284
    • Refrigerant gas R161
    • FCH2CH2
    • HFC161
    • REFRIGERANT GAS R-161
    • DTXCID3038981
    • DTXSID40200047
    • AKOS006228785
    • Ethyl fluoride or Refrigerant gas R161
    • NS00042107
    • A822739
    • Q3074512
    • Ethyl fluoride or Refrigerant gas R161 [UN2453] [Flammable gas]
    • 206-531-6

  • Applications

    Fluoroethane, also known as ethyl fluoride, CAS 353-36-6, is used primarily as a fast-evaporating solvent in niche fluorinated chemistry, serving as a reaction medium and cleaning solvent for precision equipment. It is commonly evaluated as a fluorine-containing building block or intermediate in the synthesis of fluorinated organics and specialty polymers. In coatings, inks and adhesives, it can function as a low-boiling co-solvent or formulation aid to improve flow, leveling and dry-out characteristics. It may also be used as a solvent for electronics cleaning and degreasing of metal parts and assemblies in electronics and aerospace contexts. Use is typically restricted to specific process needs and governed by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 918.38
    methanol 1604.08
    isopropanol 636.51
    water 263.37
    ethyl acetate 294.57
    n-propanol 554.94
    acetone 858.77
    n-butanol 423.51
    acetonitrile 1087.93
    DMF 1233.15
    toluene 104.23
    isobutanol 368.53
    1,4-dioxane 539.9
    methyl acetate 430.96
    THF 522.94
    2-butanone 414.19
    n-pentanol 232.73
    sec-butanol 412.92
    n-hexane 66.93
    ethylene glycol 577.46
    NMP 913.2
    cyclohexane 91.12
    DMSO 956.63
    n-butyl acetate 138.8
    n-octanol 162.02
    chloroform 1043.43
    n-propyl acetate 157.11
    acetic acid 2095.21
    dichloromethane 959.3
    cyclohexanone 447.76
    propylene glycol 424.61
    isopropyl acetate 137.26
    DMAc 824.03
    2-ethoxyethanol 395.82
    isopentanol 261.89
    n-heptane 46.27
    ethyl formate 321.19
    1,2-dichloroethane 436.11
    n-hexanol 177.89
    2-methoxyethanol 852.13
    isobutyl acetate 79.71
    tetrachloromethane 208.29
    n-pentyl acetate 119.26
    transcutol 949.61
    n-heptanol 95.22
    ethylbenzene 66.3
    MIBK 115.4
    2-propoxyethanol 322.31
    tert-butanol 526.43
    MTBE 222.93
    2-butoxyethanol 180.69
    propionic acid 683.08
    o-xylene 92.83
    formic acid 1108.58
    diethyl ether 264.15
    m-xylene 74.39
    p-xylene 94.94
    chlorobenzene 218.15
    dimethyl carbonate 136.45
    n-octane 20.12
    formamide 1056.01
    cyclopentanone 545.78
    2-pentanone 264.03
    anisole 172.07
    cyclopentyl methyl ether 222.49
    gamma-butyrolactone 670.03
    1-methoxy-2-propanol 482.03
    pyridine 520.53
    3-pentanone 216.66
    furfural 721.79
    n-dodecane 17.42
    diethylene glycol 411.61
    diisopropyl ether 56.47
    tert-amyl alcohol 366.44
    acetylacetone 311.29
    n-hexadecane 18.26
    acetophenone 176.08
    methyl propionate 285.27
    isopentyl acetate 111.2
    trichloroethylene 851.6
    n-nonanol 126.95
    cyclohexanol 337.88
    benzyl alcohol 208.5
    2-ethylhexanol 104.19
    isooctanol 73.35
    dipropyl ether 113.43
    1,2-dichlorobenzene 209.55
    ethyl lactate 123.35
    propylene carbonate 286.55
    n-methylformamide 807.97
    2-pentanol 236.04
    n-pentane 73.48
    1-propoxy-2-propanol 209.38
    1-methoxy-2-propyl acetate 134.87
    2-(2-methoxypropoxy) propanol 223.92
    mesitylene 48.65
    ε-caprolactone 374.51
    p-cymene 51.43
    epichlorohydrin 500.42
    1,1,1-trichloroethane 385.33
    2-aminoethanol 658.1
    morpholine-4-carbaldehyde 759.26
    sulfolane 661.81
    2,2,4-trimethylpentane 30.69
    2-methyltetrahydrofuran 365.31
    n-hexyl acetate 207.01
    isooctane 16.47
    2-(2-butoxyethoxy)ethanol 287.64
    sec-butyl acetate 85.57
    tert-butyl acetate 120.5
    decalin 30.46
    glycerin 582.19
    diglyme 455.67
    acrylic acid 813.18
    isopropyl myristate 72.96
    n-butyric acid 555.43
    acetyl acetate 227.52
    di(2-ethylhexyl) phthalate 85.05
    ethyl propionate 151.05
    nitromethane 1692.49
    1,2-diethoxyethane 211.58
    benzonitrile 317.61
    trioctyl phosphate 58.33
    1-bromopropane 239.17
    gamma-valerolactone 671.41
    n-decanol 86.8
    triethyl phosphate 69.47
    4-methyl-2-pentanol 99.74
    propionitrile 452.96
    vinylene carbonate 328.75
    1,1,2-trichlorotrifluoroethane 633.95
    DMS 189.06
    cumene 50.75
    2-octanol 80.97
    2-hexanone 153.88
    octyl acetate 98.72
    limonene 80.86
    1,2-dimethoxyethane 491.33
    ethyl orthosilicate 63.49
    tributyl phosphate 82.42
    diacetone alcohol 201.07
    N,N-dimethylaniline 123.81
    acrylonitrile 710.22
    aniline 247.32
    1,3-propanediol 621.51
    bromobenzene 181.4
    dibromomethane 554.07
    1,1,2,2-tetrachloroethane 580.32
    2-methyl-cyclohexyl acetate 90.25
    tetrabutyl urea 117.54
    diisobutyl methanol 60.87
    2-phenylethanol 143.84
    styrene 102.5
    dioctyl adipate 122.16
    dimethyl sulfate 237.16
    ethyl butyrate 118.27
    methyl lactate 229.07
    butyl lactate 127.81
    diethyl carbonate 90.78
    propanediol butyl ether 268.27
    triethyl orthoformate 82.94
    p-tert-butyltoluene 47.71
    methyl 4-tert-butylbenzoate 152.02
    morpholine 644.46
    tert-butylamine 335.27
    n-dodecanol 64.87
    dimethoxymethane 372.77
    ethylene carbonate 239.76
    cyrene 162.52
    2-ethoxyethyl acetate 167.96
    2-ethylhexyl acetate 85.19
    1,2,4-trichlorobenzene 250.52
    4-methylpyridine 403.61
    dibutyl ether 132.25
    2,6-dimethyl-4-heptanol 60.87
    DEF 396.52
    dimethyl isosorbide 236.07
    tetrachloroethylene 505.08
    eugenol 174.81
    triacetin 237.6
    span 80 217.12
    1,4-butanediol 249.96
    1,1-dichloroethane 473.95
    2-methyl-1-pentanol 163.01
    methyl formate 530.34
    2-methyl-1-butanol 287.44
    n-decane 29.08
    butyronitrile 374.21
    3,7-dimethyl-1-octanol 130.02
    1-chlorooctane 87.09
    1-chlorotetradecane 35.05
    n-nonane 30.94
    undecane 21.28
    tert-butylcyclohexane 29.21
    cyclooctane 23.64
    cyclopentanol 426.62
    tetrahydropyran 389.8
    tert-amyl methyl ether 160.71
    2,5,8-trioxanonane 334.55
    1-hexene 145.24
    2-isopropoxyethanol 213.63
    2,2,2-trifluoroethanol 604.87
    methyl butyrate 209.98

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction