Fluopyram

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  • Identifiers

    CAS number
    658066-35-4

    Molecular formula
    C16H11ClF6N2O

    SMILES
    C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F

    Safety labels

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 53.33%
    Cooling 28.33%
    Savory 26.77%
    Animal 22.55%
    Meaty 20.02%
    Sweet 19.92%
    Grape 18.88%
    Cooked 18.51%
    Bitter 18.34%
    Milky 18.29%

     

    Flavor
    Bitter 60.82%
    Odorless 44.47%
    Bland 26.96%
    Mild 24.08%
    Sweet-like 20.1%
    Nitrile 19.2%
    Scallion 18.41%
    Very strong 18.15%
    Cedarleaf 18.12%
    Taco 17.98%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.5

    pKa est.
    4.09 (weak acid)

    Molecular weight
    396.71 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    410°C

    Flash point

    • 143.8 ˚C est.

  • Synonyms

    • Fluopyram
    • 658066-35-4
    • F0VT7K5302
    • N-{2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl}-alpha,alpha,alpha-trifluoro-o-toluamide
    • DTXSID9058151
    • CHEBI:83070
    • N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide
    • N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]ethyl}-alpha,alpha,alpha-trifluoro-o-toluamide
    • RefChem:140867
    • DTXCID1031919
    • 619-797-7
    • Fluopyram [ISO]
    • N-[2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-2-(trifluoromethyl)benzamide
    • N-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl}-2-(trifluoromethyl)benzamide
    • MFCD17166960
    • N-[2-[3-Chloro-5-(trifluoromethyl)-2-pyridyl]ethyl]-2-(trifluoromethyl)benzamide
    • N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide
    • n-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-2-trifluoromethylbenzamide
    • UNII-F0VT7K5302
    • N-(2-(3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL)ETHYL)-2-(TRIFLUOROMETHYL)BENZAMIDE
    • Fluopyram (Standard)
    • AE C656948
    • Fluopyram 100 microg/mL in Acetonitrile
    • C16H11ClF6N2O
    • SCHEMBL67230
    • CHEMBL2286755
    • SCHEMBL29353266
    • MSK21315
    • AKOS027323805
    • EBC-249092
    • HY-119459R
    • DA-53246
    • FF101744
    • MS-26696
    • SY272473
    • HY-119459
    • CS-0068436
    • NS00001768
    • Fluopyram, PESTANAL(R), analytical standard
    • G13912
    • A902453
    • EN300-20367994
    • Q15632704
    • Benzamide, N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-2-(trifluoromethyl)-
    • N-(2-(3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDYL)ETHYL)-.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-O-TOLUAMIDE
    • 658066-35-4

  • Applications

    Fluopyram (CAS 658066-35-4) is an SDHI fungicide active ingredient used in agriculture to control fungal diseases on a broad range of crops. Typical use forms include foliar sprays and soil treatments to provide systemic protection, and it is also used in seed-treatment formulations for treated seeds; it can be applied to both greenhouse and field crops. Fluopyram is commonly formulated in combination products with other fungicides, and its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 67.94
    methanol 115.13
    isopropanol 32.53
    water 0.03
    ethyl acetate 79.4
    n-propanol 44.98
    acetone 147.2
    n-butanol 33.81
    acetonitrile 52.45
    DMF 375.15
    toluene 55.54
    isobutanol 24.21
    1,4-dioxane 133.61
    methyl acetate 123.54
    THF 383.15
    2-butanone 124.6
    n-pentanol 21.51
    sec-butanol 36.93
    n-hexane 0.51
    ethylene glycol 14.53
    NMP 348.83
    cyclohexane 0.84
    DMSO 417.21
    n-butyl acetate 37.4
    n-octanol 8.77
    chloroform 74.44
    n-propyl acetate 44.47
    acetic acid 77.04
    dichloromethane 125.82
    cyclohexanone 100.09
    propylene glycol 15.7
    isopropyl acetate 38.87
    DMAc 394.33
    2-ethoxyethanol 99.14
    isopentanol 24.07
    n-heptane 1.05
    ethyl formate 49.68
    1,2-dichloroethane 81.9
    n-hexanol 21.41
    2-methoxyethanol 206.47
    isobutyl acetate 11.85
    tetrachloromethane 4.66
    n-pentyl acetate 34.81
    transcutol 153.19
    n-heptanol 14.77
    ethylbenzene 16.17
    MIBK 30.61
    2-propoxyethanol 98.47
    tert-butanol 30.19
    MTBE 40.94
    2-butoxyethanol 54.08
    propionic acid 42.83
    o-xylene 30.03
    formic acid 57.37
    diethyl ether 56.98
    m-xylene 22.05
    p-xylene 14.86
    chlorobenzene 23.01
    dimethyl carbonate 71.88
    n-octane 0.44
    formamide 150.26
    cyclopentanone 186.86
    2-pentanone 77.67
    anisole 66.41
    cyclopentyl methyl ether 76.06
    gamma-butyrolactone 218.94
    1-methoxy-2-propanol 115.36
    pyridine 168.91
    3-pentanone 67.34
    furfural 191.01
    n-dodecane 0.41
    diethylene glycol 65.73
    diisopropyl ether 8.77
    tert-amyl alcohol 37.97
    acetylacetone 105.43
    n-hexadecane 0.48
    acetophenone 66.28
    methyl propionate 98.32
    isopentyl acetate 24.21
    trichloroethylene 162.3
    n-nonanol 9.81
    cyclohexanol 24.28
    benzyl alcohol 46.18
    2-ethylhexanol 11.5
    isooctanol 9.96
    dipropyl ether 24.18
    1,2-dichlorobenzene 23.43
    ethyl lactate 29.3
    propylene carbonate 65.79
    n-methylformamide 158.07
    2-pentanol 20.4
    n-pentane 1.0
    1-propoxy-2-propanol 53.22
    1-methoxy-2-propyl acetate 62.84
    2-(2-methoxypropoxy) propanol 51.61
    mesitylene 8.39
    ε-caprolactone 99.55
    p-cymene 10.09
    epichlorohydrin 302.99
    1,1,1-trichloroethane 33.87
    2-aminoethanol 32.78
    morpholine-4-carbaldehyde 279.18
    sulfolane 256.21
    2,2,4-trimethylpentane 0.75
    2-methyltetrahydrofuran 148.4
    n-hexyl acetate 33.78
    isooctane 0.35
    2-(2-butoxyethoxy)ethanol 71.14
    sec-butyl acetate 23.25
    tert-butyl acetate 40.82
    decalin 0.69
    glycerin 29.87
    diglyme 159.11
    acrylic acid 49.82
    isopropyl myristate 11.35
    n-butyric acid 45.37
    acetyl acetate 45.87
    di(2-ethylhexyl) phthalate 18.0
    ethyl propionate 45.88
    nitromethane 250.06
    1,2-diethoxyethane 54.76
    benzonitrile 34.5
    trioctyl phosphate 10.0
    1-bromopropane 33.94
    gamma-valerolactone 253.42
    n-decanol 7.35
    triethyl phosphate 17.27
    4-methyl-2-pentanol 9.55
    propionitrile 38.88
    vinylene carbonate 61.97
    1,1,2-trichlorotrifluoroethane 141.58
    DMS 48.49
    cumene 8.05
    2-octanol 8.78
    2-hexanone 44.72
    octyl acetate 19.36
    limonene 13.38
    1,2-dimethoxyethane 169.39
    ethyl orthosilicate 15.78
    tributyl phosphate 10.78
    diacetone alcohol 56.8
    N,N-dimethylaniline 38.56
    acrylonitrile 68.22
    aniline 55.0
    1,3-propanediol 45.12
    bromobenzene 23.32
    dibromomethane 60.11
    1,1,2,2-tetrachloroethane 105.05
    2-methyl-cyclohexyl acetate 26.44
    tetrabutyl urea 23.21
    diisobutyl methanol 6.13
    2-phenylethanol 44.17
    styrene 21.71
    dioctyl adipate 24.02
    dimethyl sulfate 123.76
    ethyl butyrate 32.27
    methyl lactate 61.38
    butyl lactate 27.84
    diethyl carbonate 24.01
    propanediol butyl ether 31.52
    triethyl orthoformate 23.69
    p-tert-butyltoluene 9.12
    methyl 4-tert-butylbenzoate 52.69
    morpholine 191.15
    tert-butylamine 13.26
    n-dodecanol 5.05
    dimethoxymethane 248.82
    ethylene carbonate 41.86
    cyrene 70.75
    2-ethoxyethyl acetate 74.11
    2-ethylhexyl acetate 19.36
    1,2,4-trichlorobenzene 35.81
    4-methylpyridine 134.35
    dibutyl ether 11.35
    2,6-dimethyl-4-heptanol 6.13
    DEF 125.37
    dimethyl isosorbide 103.34
    tetrachloroethylene 61.14
    eugenol 53.27
    triacetin 51.64
    span 80 37.49
    1,4-butanediol 14.32
    1,1-dichloroethane 43.19
    2-methyl-1-pentanol 19.06
    methyl formate 121.73
    2-methyl-1-butanol 30.47
    n-decane 0.67
    butyronitrile 29.69
    3,7-dimethyl-1-octanol 8.23
    1-chlorooctane 4.66
    1-chlorotetradecane 1.91
    n-nonane 0.53
    undecane 0.52
    tert-butylcyclohexane 0.59
    cyclooctane 0.34
    cyclopentanol 34.49
    tetrahydropyran 78.01
    tert-amyl methyl ether 42.78
    2,5,8-trioxanonane 108.79
    1-hexene 5.17
    2-isopropoxyethanol 46.74
    2,2,2-trifluoroethanol 29.48
    methyl butyrate 53.96

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction